Thomas Badet
@tbadet.bsky.social
74 followers 66 following 4 posts
Junior researcher at the university of Neuchâtel - fungi enthousiast
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tbadet.bsky.social
🔥 Exciting news! The first Symposium on Repeat-Induced Point mutations is happening June 30 – July 1 at the University of Neuchâtel🇨🇭!

🔹 Want to join? Register here > forms.gle/XWTd4gJAXZSx...

🚨 Limited spots available! So first come, first served!

🔹 More info > crolllab.github.io/ripm2025/
RIPM 2025
Symposium on Repeat-induced Point Mutation research, 30.6 - 1.7, Neuchatel, Switzerland
crolllab.github.io
Reposted by Thomas Badet
jromeijn.bsky.social
The first paper of my PhD is now available as a preprint! 🎉

Transposable elements (TEs) don't just jump within fungal genomes, they also move extensively between species. In this study, we screened over 1,300 fungal genomes and found a conservative estimate of 5,500+ horizontal transfer events.
www.biorxiv.org
Reposted by Thomas Badet
ccilelorrain.bsky.social
Excited to share the first PhD preprint of @iglavincheska.bsky.social — now on bioRxiv!
We explored the 3D genome of Zymo and found:
🧬 Rabl-like conformation
🧩 Accessory chr tethered to core centromeres
🏰 Self-interacting domains and boundaries with insulator motifs
www.biorxiv.org/content/10.1...
tbadet.bsky.social
🚨 Don't forget to register! 🚨

ℹ️ Deadline is set to May 23rd.

🔥 Many slots are still available.
tbadet.bsky.social
🔥 Exciting news! The first Symposium on Repeat-Induced Point mutations is happening June 30 – July 1 at the University of Neuchâtel🇨🇭!

🔹 Want to join? Register here > forms.gle/XWTd4gJAXZSx...

🚨 Limited spots available! So first come, first served!

🔹 More info > crolllab.github.io/ripm2025/
RIPM 2025
Symposium on Repeat-induced Point Mutation research, 30.6 - 1.7, Neuchatel, Switzerland
crolllab.github.io
tbadet.bsky.social
And shoutout to the other members of the organising committee @oggenfussursula.bsky.social and @danielcroll.bsky.social
tbadet.bsky.social
🔥 The event will bring together molecular biologists, evolutionary geneticists, and bioinformaticians to explore RIP’s role in transposable element control, genome integrity, and fungal adaptation.

Looking forward to seeing you in Neuchâtel! 🏔️ #RIPM2025 #FungalGenomics #EvolutionaryBiology
tbadet.bsky.social
🔥 Exciting news! The first Symposium on Repeat-Induced Point mutations is happening June 30 – July 1 at the University of Neuchâtel🇨🇭!

🔹 Want to join? Register here > forms.gle/XWTd4gJAXZSx...

🚨 Limited spots available! So first come, first served!

🔹 More info > crolllab.github.io/ripm2025/
RIPM 2025
Symposium on Repeat-induced Point Mutation research, 30.6 - 1.7, Neuchatel, Switzerland
crolllab.github.io
Reposted by Thomas Badet
danielcroll.bsky.social
@guidopuccetti.bsky.social, Gabriel Scalliet and I are excited to share our latest work.

Resistance in agriculture emerges fast, but we fail to grasp how the myriad mutations in pathogen populations contribute to this.

Please check out and share our latest preprint: www.biorxiv.org/content/10.1...
Reposted by Thomas Badet
fungage-lab.bsky.social
We did it! We caught Starship #transposons moving between #fungal species in the lab, including between species separated by ~100my. We think Starships are a mediator of HGT in fungi, akin to conjugative elements in bacteria. Check out the preprint. www.biorxiv.org/content/10.1...
Illustration depicting the ways in which fungi can exchange genetic material with each other. Starship mediated HGT is confirmed experimentally in this preprint.
Reposted by Thomas Badet
ccilelorrain.bsky.social
Great talk @iglavincheska.bsky.social, exploring the impact of DNA methylation variation on the 3D genome structure of Zymoseptoria tritici!
#ecfg17
Reposted by Thomas Badet
francoissabot.bsky.social
Do you want to annotate your #pangenome graph and its embedded genome ? Then GrAnnoT is for you !
🖥️🧬 🧪

In the present paper, our PhD student Nina Marthe developed a Python tool, a user friendly one, that allows to
1/5

www.biorxiv.org/content/10.1...
www.biorxiv.org
Reposted by Thomas Badet
fungage-lab.bsky.social
Interested in #fungal accessory chromosomes or toxin/antidote genes? Check out our new preprint! We show that the Spok gene family in Fusarium include active toxin/antidote genes. We present a model for how these genes influence the evolution of fungal genomes. www.biorxiv.org/content/10.1...
Illustration of FuSpok killing a cell which has lost an accessory chromosome. Core chromosome in blue, accessory chromosome in red. Black circle: FuSpok. Green circle: antidote function. Red triangle: toxin function.
Reposted by Thomas Badet
drjorhodes.com
This looks a fascinating read!
danielcroll.bsky.social
@tbadet.bsky.social and I have a preprint out on transposon silencing in fungi!

Genome size evolution is fascinating and showcases the dynamic nature of transposon activation.

What we understand less are the dynamics of transposon defense systems encoded by the genomes.

doi.org/10.1101/2025...
Fungal phylogeny highlighting genome size changes Summary of genome size variation among groups
Reposted by Thomas Badet
piosierra.bsky.social
TEs at work.
Very interesting results.
danielcroll.bsky.social
@tbadet.bsky.social and I have a preprint out on transposon silencing in fungi!

Genome size evolution is fascinating and showcases the dynamic nature of transposon activation.

What we understand less are the dynamics of transposon defense systems encoded by the genomes.

doi.org/10.1101/2025...
Fungal phylogeny highlighting genome size changes Summary of genome size variation among groups
Reposted by Thomas Badet
danielcroll.bsky.social
@tbadet.bsky.social and I have a preprint out on transposon silencing in fungi!

Genome size evolution is fascinating and showcases the dynamic nature of transposon activation.

What we understand less are the dynamics of transposon defense systems encoded by the genomes.

doi.org/10.1101/2025...
Fungal phylogeny highlighting genome size changes Summary of genome size variation among groups
Reposted by Thomas Badet
biorxiv-evobio.bsky.social
A systematic screen for genetic factors underpinning transposon defense systems across the fungal kingdom https://www.biorxiv.org/content/10.1101/2025.01.10.632494v1