This scientist is revealing the immune system in our nasal passages. With a focus on the upper airway, Sydney Ramirez is working toward better diagnoses, vaccines.
www.statnews.com/2025/10/16/s...
#STATWunderkinds

Well, this is exciting! An autoimmune mechanism for the horrible disease ALS has been identified, for the first time. #ImmunoSky
🧪
www.nature.com/articles/s41...

David Baltimore, for much of the past three decades, has been one of my most helpful, thoughtful sources. I wrote an obit about his remarkable career, and I included a few of my interactions with him. www.science.org/content/arti...

These kind of analyses and tech only improves our flu vaccine strain selection, hopefully leading to overall higher vaccine effectiveness.

Inclusion of #dementia in the WHO’s and UN’s discussions about non-communicable diseases could drastically change attitudes worldwide and could improve access to care and support for people living with the condition and their carers, writes Paola Barbarino in Nature. 🧪

After 8 months of peer review, our manuscript was published today @nature.com showing that bovine H5N1 viruses bind poorly to human-type sialic acid receptors. We now know that the virus is only 1 HA substitution away from efficiently binding human receptors.

www.nature.com/articles/s41...

H5N1 strain-specific antibodies are higher in older individuals and correlate more with birth year than with age, suggesting that younger individuals are potentially more likely to benefit from H5N1 vaccination, according to a paper in Nature Medicine. https://go.nature.com/4hFLOa5 🧪

Couldn’t be happier to see this out. It was a fun collaboration with the talented @cobey.bsky.social lab. Access to vital clinical resources and powerful tech at Penn allowed us look at Ab levels in this cohort to help answer these questions.

Today @natmedicine.bsky.social published our study showing the older individuals born prior to 1968 have more antibodies that cross-react to #H5N1 relative to younger individuals. If H5N1 causes a pandemic, children will likely be the most susceptible. 1/2

www.nature.com/articles/s41...

Very close to my heart. The power of vaccines and basic research merging to help patients. We need more of it!

Dementia risk, higher than thought, requires a national strategy: Policies and industries that promote healthy aging are imperative www.statnews.com/2025/01/18/d... #AlzheimersDisease #dementia #healthcare

Research published Tuesday is the first to connect the dots between a common herpes virus, head injury, and Alzheimer's.

Immunofocusing on the conserved fusion peptide of HIV envelope glycoprotein in rhesus macaques https://www.biorxiv.org/content/10.1101/2024.11.27.625755v1

📢Hot off the press! Our latest work studying #influenza broadly neutralizing antibody development in humanized mice. Huge thanks to everyone involved in the study🙏 #NIAID #VRC #Ragon #Scripps www.cell.com/cell-reports...

This #glycotime work by @virusesimmunity.bsky.social is intriguing; terminal GlcNAc is a viral epitope recognized by Abs that keep endogenous retroviruses at bay. Must be something about the context of that GlcNAc, would love to see some followup structural biology.

www.science.org/doi/10.1126/...

Last week, a teenager in British Columbia contracted H5N1, the first human case acquired in Canada. The BC CDC and and Canadian Food Inspection Agency have released sequences from this infected person and domestic and wild birds sampled in BC, which we've just added to Nextstrain. A thread: