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Reposted by Katy Brown

denzquix @denzquix.bsky.social · 16d

I translated "Jeff Jet: Abenteuer InfoHighway" as "Jeff Jet: Adventure on the InfoHighway" archive.org/details/jeff... - a German promotional adventure game for Hewlett Packard from 1995.

Title screen for "Jeff Jet: Adventure on the InfoHighway".

Screenshot from "Jeff Jet: Adventure on the InfoHighway". In front of a green room that seems to be built out of giant circuit board pieces, there are close-up pictures of Jeff Jet and an NPC wearing glasses and a red sweater. A line of dialog is visible between them: "Good day to you!".

Screenshot from "Jeff Jet: Adventure on the InfoHighway". The two main characters, Jeff and Donna, are standing near a road tunnel with a closed barrier gate in front of it and a guard standing by. There is a large truck loaded with gigantic ones and zeroes. The mouse cursor is hovering over these ones and zeroes, and the word "Bits" appears next to it.

Screenshot from "Jeff Jet: Adventure on the InfoHighway". One of the main characters, Donna, stands in the middle of a large desert tent with visible patches and holes. A small office area has been set up behind her, with a woman sitting at a desk with a computer on it. There is an empty chair with a green coat lying on it in the foreground facing the desk. At the bottom of the screen, there is a row of inventory items. The mouse cursor is over one of them, a red and green magnet, with the word "Magnet" shown next to it.

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Katy Brown @thekatybrown.bsky.social · Jul 23

Come to the BOKR session at 2:20 and see Charlotte Tumescheit @schnamo.bsky.social give a super interesting talk about improving prediction of molecular properties by incorporating ontologies. #ISMBECCB2025

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Katy Brown @thekatybrown.bsky.social · Jul 23

Someone needs to implement an LLM to help select which talks to go to at #ISMBECCB2025

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Katy Brown @thekatybrown.bsky.social · Jul 22

Come and see me in the ice rink if you want to plot phylogenies in matplotlib! Poster 206. GitHub.com/KatyBrown/plot_phylo #ISMBECCB2025

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Katy Brown @thekatybrown.bsky.social · Jul 21

You ring the doorbell on Oncology, just show any card, they won't check, then go down two floors in the lift, around the corner and then up one floor, once you get outside climb over the fence, scrabble up the verge, sign in as a visitor and you're there.

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Katy Brown @thekatybrown.bsky.social · Jul 21

It's the same in the UK. They specialise in roads which look like they link together but there's a huge fence or mysterious ditch blocking the way, or they've joined two buildings across the gap but not added a door to let people through.

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Reposted by Katy Brown

mmarchin.bsky.social @mmarchin.bsky.social · Jul 21

I reformatted the #ISMBECCB2025 schedule a bit - in case anyone else wants to use it this way - ordered by day and start time:

csv: drive.google.com/file/d/1JyhT...

xlsx:
docs.google.com/spreadsheets...

ISMBECCB_2025_All_Detailed_Schedule.csv

drive.google.com

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Katy Brown @thekatybrown.bsky.social · Jul 21

Thank you! This is amazing.

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Katy Brown @thekatybrown.bsky.social · Jul 21

Excited for the ISMB/ECCB conference! I have two posters A520 today about an endogenous and exogenous virus I found in nematodes - and B206 tomorrow about my tool plot_phylo for drawing phylogenies in matplotlib. #ISMBECCB2025

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Katy Brown @thekatybrown.bsky.social · Jul 9

And the same colour!

Katy Brown @thekatybrown.bsky.social · Jul 9

Is it so much to ask for all my bullet points to be 1. the same size and 2. in a straight line?

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Katy Brown @thekatybrown.bsky.social · Jun 27

I could do my job in half the time if we just picked a column delimiter and stuck with it and then no-one can use that symbol for anything else. Let's not use * to both delimit columns and represent a stop codon, or use a random number of spaces, or put "_" in our sequence IDs. 🖥️🧪

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Reposted by Katy Brown

PLOS Biology @plosbiology.org · Jun 24

From student to researcher, a #career in #science can come with a high price tag. @drcraigmc.bsky.social explores how wealth shapes opportunity in #STEM and proposes structural changes to support #equity and inclusion. 🧪
plos.io/4edGlY4

Too poor to science: How wealth determines who succeeds in STEM

From student to researcher, a career in science can come with a high price tag. This Perspective explores how persistent financial barriers limit who can succeed in science, revealing how wealth shape...

plos.io

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Reposted by Katy Brown

Dr Phoenix CS Andrews @thatdocphoenix.com · Jun 23

There should be a ban on broadcasters using footage of “anonymous” (heads cropped out) larger people - who could nevertheless recognise themselves based on knowing their own bodies and clothes - to illustrate stories about obesity, fat or weight loss

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Katy Brown @thekatybrown.bsky.social · Jun 23

Are you interested in using AI to decode RNA? Have a look at this brilliant new review from my friend @schnamo.bsky.social and her colleagues.

Charlotte Tumescheit @schnamo.bsky.social · Jun 23

New Review Paper Alert! Are you interested in how to use AI to decode RNA? Check it out here
www.nature.com/articles/s41...
@jannahastings.bsky.social @vincentjung.bsky.social

Decoding the interactions and functions of non-coding RNA with artificial intelligence - Nature Reviews Molecular Cell Biology

Studying RNA function is constrained by limitations of traditional methods. This Roadmap discusses how artificial intelligence (AI) can enhance the study of how non-coding regions of mRNA regulate its...

www.nature.com

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Katy Brown @thekatybrown.bsky.social · Jun 4

Just a reminder to please fill out this form if you’d be interest in an EVE / ERV meeting 📋🥳

Katy Brown @thekatybrown.bsky.social · May 27

I'm thinking of organising a meeting on endogenous viral elements (RNA, DNA and retroviral) - if you'd potentially be interested, please fill out the form here - forms.gle/wrCiWMw4yXZe... - so I can gauge interest. Please RT or share with anyone maybe interested! 🧪🧬🖥️🦠 #virology #bioinformatics

EVE Meeting Expression of Interest

forms.gle

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Reposted by Katy Brown

Sean Eddy @cryptogenomicon.bsky.social · May 22

NIH funding supporting the HMMER and Infernal software projects has been terminated. NIH states that our work, as well as all other federally funded research at Harvard, is of no benefit to the US.

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Katy Brown @thekatybrown.bsky.social · May 28

@ariskatzourakis.bsky.social @robjgifford.bsky.social @lequimelab.eu @emma-harding.bsky.social

Katy Brown @thekatybrown.bsky.social · May 27

I'm thinking of organising a meeting on endogenous viral elements (RNA, DNA and retroviral) - if you'd potentially be interested, please fill out the form here - forms.gle/wrCiWMw4yXZe... - so I can gauge interest. Please RT or share with anyone maybe interested! 🧪🧬🖥️🦠 #virology #bioinformatics

EVE Meeting Expression of Interest

forms.gle

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Katy Brown @thekatybrown.bsky.social · May 27

I'm thinking of organising a meeting on endogenous viral elements (RNA, DNA and retroviral) - if you'd potentially be interested, please fill out the form here - forms.gle/wrCiWMw4yXZe... - so I can gauge interest. Please RT or share with anyone maybe interested! 🧪🧬🖥️🦠 #virology #bioinformatics

EVE Meeting Expression of Interest

forms.gle

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Reposted by Katy Brown

denzquix @denzquix.bsky.social · May 16

"Action in Hollywood" is one of several promotional games released in the 1990s for Bi-Fi Rolls, a salami-based snack originating in Germany and sold across Europe.

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Reposted by Katy Brown

denzquix @denzquix.bsky.social · May 16

I translated "Bi-Fi: Action in Hollywood" (1994) for MS-DOS, one of the more ambitious and fully-developed promotional games of the era. Huge thanks to @sonneveld.bsky.social for helping me with the technical aspects on this one. archive.org/details/bifi...

A scene from "Bi-Fi: Action in Hollywood". On a sci-fi set, the main character Lukas is talking to a man whose bottom half is trapped in a small hatch. There is a conversation menu with three options: "What are you doing in there?" "Want me to heave you out of there?" "How can I help?"

A scene from "Bi-Fi: Action in Hollywood". Lukas is standing in the doorway of the studio cafeteria. A couple of people are seated on the tables. The mouse cursor is hovering over a Bi-Fi Roll in the player's inventory and the action line reads "Eat Bi-Fi Roll".

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Katy Brown @thekatybrown.bsky.social · May 11

Excited for #RdRpSummit2025 and #ViBioM2025! Just starting off now in Lisbon.

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Reposted by Katy Brown

RdRp Summit @rdrpsummit.bsky.social · May 11

Here we go! The #RdRpSummit2025 is live!
@ingrida.bsky.social

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Reposted by Katy Brown

denzquix @denzquix.bsky.social · Apr 29

v1.0 of "King's Quest 1: Rubber Tree Edition" is up! Apply the mod here: denzquix.github.io/agi-patch/ You will need the files from the non-enhanced DOS version. The patched files will run in ScummVM under the "Fan AGI" option, or in DOSBox if you include other files from the original game folder.

denzquix @denzquix.bsky.social · Nov 14

Current project: a mod for King's Quest 1 (AGI) which adds >UNDO and circumvents softlocks, titled King's Quest: Rubber Tree Edition. A pre-release version was recently featured on stream by the inimitable @emmxyzzy.bsky.social

An edited demo clip of the King's Quest 1 "Rubber Tree Edition" mod, showing Graham falling from a giant beanstalk while climbing it, but the player types "undo" while he plummets, which instantly places him safely back where he fell from.

A screenshot of the intro screen for the Rubber Tree Edition mod for King's Quest 1. It reads:

Let it be Known that this Rendition of "KING'S QUEST" is an Unsanctioned MODIFICATION, concocted by THE ORDER OF THE RUBBER TREE. Acolytes of this elusive Sect do Conspire from the Shadows, manipulating Events to avert so-called UNWINNABLE SITUATIONS; Furthermore, they claim the right to overrule DEATH ITSELF via the use of the arcane incantation "UNDO". Those who Abide by this Sacrilegious "NERFING" do so at the Risk to their very Souls. Rubber Tree Edition version 1.0 Beta 2.

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Reposted by Katy Brown

Martin Steinegger 🇺🇦 @martinsteinegger.bsky.social · Apr 25

Visit our posters at #RECOMB2025 for:

Structural: MSAs, Virus DB, Core Genes, Motif Discovery, Multimer Clustering & Search, pLM Foldseek, Environmental analysis

Metagenomics: Classification & Metabuli App

GPU-based & RNA search, Proteome clustering, Novel Ribozyme discovery

& get Marv stickers!

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