Sonika Tyagi
@tsonika.bsky.social
130 followers 250 following 67 posts
Academic @RMIT University Affiliated @MonashUniv #computationalbiology #digitalhealth #MachineLearning #AI #LLM #genomics #data4diversity #aiforsocialgood #equityDiversityInclusion
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Reposted by Sonika Tyagi
Reposted by Sonika Tyagi
icthealth.nl
ChatGPT scores up to 97% on medical facts — yet fails to read symptoms. Experts like Ahmed Abdeen Hamed and Dr Andrew Thornton warn: AI can inform, not diagnose. The real challenge now? Using it responsibly in healthcare. #healthcare
AI performs well on facts, but fails when it comes to symptoms | ICT&health Global
An important explanation lies in the nature of the language ChatGPT uses. Even more worrying is that it does not indicate when it does not know something.
www.icthealth.org
Reposted by Sonika Tyagi
naimavahab.bsky.social
A versatile machine learning pipeline to find co-regulatory modules (CRMs) in DNA.
Check it out and explore: doi.org/10.1016/j.co...

#Genomics #Epigenomics #MachineLearning #CardiacResearch #OpenScience

@tyagilab.bsky.social @tsonika.bsky.social
Reposted by Sonika Tyagi
aashishbhandari.com
🩺 Missing medical data isn't just something to fill in or ignore!
EHRs often have missing values. Common fix? Imputation. But filling gaps can mislead predictions.
We explore ML approaches to handle missingness while preserving the original data distribution.
📜 www.researchsquare.com/article/rs-6...
Mind the Gaps: Guess Less, Predict More with Missing Medical Data
Healthcare data, generally available as electronic health records (EHR), provide a rich profile of an individual’s health and lifestyle. This data can be harnessed for predictive modelling using machi...
www.researchsquare.com
tsonika.bsky.social
Congratulations 🍾
Reposted by Sonika Tyagi
lornegenome.bsky.social
Earlybird registration & abstract submissions now open for the 𝟒𝟕𝐭𝐡 𝐋𝐨𝐫𝐧𝐞 𝐆𝐞𝐧𝐨𝐦𝐞 𝐂𝐨𝐧𝐟𝐞𝐫𝐞𝐧𝐜𝐞, 𝟏𝟓-𝟏𝟖𝐭𝐡 𝐅𝐞𝐛 𝟐𝟎𝟐𝟔: https://www.lornegenome.org/registrations (deadline 7th Nov 2025)

Speakers: https://www.lornegenome.org/speakers

We look forward to seeing you there!
Speakers — Lorne Genome
No description found
www.lornegenome.org
tsonika.bsky.social
Naima is developing foundation models for RNA therapeutic applications.
Fantastic presentation, keep up the good work 🥳
tsonika.bsky.social
Kudos to Naima Vahab for presenting her PhD research at "Storytelling for Impactful Research (STIR) Competition " at RMIT STEM College. What an amazing opportunity for polishing your #scicomm skills and knowledge sharing across STEM disciplines.

@tyagilab.bsky.social @rmitcomputing.bsky.social
Reposted by Sonika Tyagi
bioinfoadv.bsky.social
🧠 Just out in Bioinformatics Advances: “Predicting gene expression using millions of yeast promoters reveals cis-regulatory logic”  

Explore the paper here: https://doi.org/10.1093/bioadv/vbaf130

Authors include: @susbo.bsky.social
Reposted by Sonika Tyagi
Reposted by Sonika Tyagi
dlingenfelter.bsky.social
SARS-CoV-2 causes systemic vascular damage via viral proteins and immune dysregulation, driving acute organ failure and Long COVID.

Vaccination reduces these risks significantly.
davidlingenfelter.substack.com/p/the-vascul...
🧬 FOR IMMEDIATE RELEASE 

SARS-CoV-2 Confirmed as a Vascular Pathogen: New Report Details Mechanisms Behind Acute and Long-Term Damage

August 18, 2025 — El Cerrito, CA - A newly revised scientific report by David Lingenfelter, PhD, synthesizes global consensus and cutting-edge research to confirm that SARS-CoV-2 is not merely a respiratory virus—it is a systemic vascular pathogen. The report, originally generated via Google’s Gemini AI and refined through critique and reanalysis, offers a comprehensive account of the virus’s multifaceted assault on the vascular system.
🔍 Key Findings:
•	Endothelial Dysfunction as Central Pathology: SARS-CoV-2 disrupts vascular homeostasis via Spike protein–ACE2 interactions, Nucleocapsid protein–TLR2 signaling, and immune-mediated inflammation.
•	Microvascular Injury Drives Organ Failure: COVID-19-associated coagulopathy (CAC), microthrombosis, and vasculitis contribute to acute morbidity and mortality.
•	Long COVID Linked to Persistent Vascular Damage: Chronic endotheliopathy, fibrinaloid microclots, and senescent “zombie cells” underlie post-acute sequelae.
•	Vaccination Reduces Vascular Risk: Comparative data show significantly lower rates of cardiac complications post-vaccination versus post-infection.
🧠 Implications for Clinical Practice and Public Health:
•	COVID-19 should be classified as a systemic vascular disease.
•	Diagnostic protocols must incorporate endothelial biomarkers and advanced imaging.
•	Therapeutic strategies should target inflammation, thrombosis, and senescence.
•	Long-term surveillance is needed to assess cardiovascular risk in survivors.
📚 Future Directions: The report calls for randomized trials of senolytics, microclot-targeting therapies, and personalized vascular risk profiling. It also urges public health systems to prioritize vascular health as a pandemic preparedness measure.
🔗 Full report available on https://davidlingenfelter.substack.com/p/the-vascular-pathophysiology-of-sars-b2d
Reposted by Sonika Tyagi
bhanlon15.bsky.social
SciTech Daily: 'Scientists Detect “Ghost” Proteins That Could Explain Long COVID'

'Scientists have uncovered viral protein fragments lingering in the blood of long COVID patients, potentially offering the first measurable biomarker for the condition.'

scitechdaily.com/scientists-d...
Scientists Detect “Ghost” Proteins That Could Explain Long COVID
Researchers discovered viral fragments in blood samples from long COVID patients, hinting at a possible biomarker. The findings suggest the virus may linger in hidden reservoirs, fueling ongoing sympt...
scitechdaily.com
tsonika.bsky.social
Contributions to review on graph learning:
cslg-bot.bsky.social
Falih Gozi Febrinanto, Adonia Simango, Chengpei Xu, Jingjing Zhou, Jiangang Ma, Sonika Tyagi, Feng Xia: Refined Causal Graph Structure Learning via Curvature for Brain Disease Classification https://arxiv.org/abs/2506.15708 https://arxiv.org/pdf/2506.15708 https://arxiv.org/html/2506.15708
Reposted by Sonika Tyagi
lancetmicrobe.bsky.social
New comment

A layered strategy for tackling antimicrobial resistance: the Swiss cheese model for policy, prevention, and engagement

www.thelancet.com/journals/lan...

#IDSky #ClinMicro #AMR #OpenAccess #OA
The antimicrobial resistance Swiss cheese model