Taufik A. Valiante
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tvaliante.bsky.social
Taufik A. Valiante
@tvaliante.bsky.social
190 followers 190 following 10 posts
Neuroscientist, Neurosurgeon, Krembil Brain Institute, CRANIA, MPUTC, BME & ECE University of Toronto.
https://neurontobrainlaboratory.ca
https://kite-uhn.com/crania
https://mpc.utoronto.ca
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Reposted by Taufik A. Valiante
alleninstitute.org
🧠📢 New preprint alert

Large-scale ephys is exploding but spike sorting remains the computational bottleneck. A 2-hr, 6-probe Neuropixels 2.0 Quad Base session can take over a week to sort on a single machine. Here's a better solution. 🧵

#neuroskyence #compneurosky
December 5, 2025 at 8:42 PM
Reposted by Taufik A. Valiante
alleninstitute.org
Lossy WavPack compression (up to 7× reduction) has minimal impact on sorting accuracy. This offers major storage savings without sacrificing quality.
December 5, 2025 at 8:42 PM
Reposted by Taufik A. Valiante
dirkbwalther.bsky.social
Energy efficiency drives evolution, and humans may have evolved pleasure-based signals to optimize actions. Does this extend to aesthetic pleasure?

Yes!

Strong evidence in silico and humans, out in PNAS Nexus:
tinyurl.com/3kbu8xw4

With Yikai Tang and Wil Cunningham.
@uoftpsychology.bsky.social
Conceptual Roadmap of the present study. To examine the relationship between the metabolic costs of visual processing and aesthetic pleasure, we used both computational and physiological measures to quantify metabolic costs during visual processing: 1. Model-derived estimates of metabolic costs based on the activation of a deep neural network; 2. Metabolic activity of human brains, specifically in the visual processing areas. We found that both measures were inversely related to aesthetic pleasure.
December 2, 2025 at 5:43 PM
Reposted by Taufik A. Valiante
rdgao.bsky.social
Finally got the job ad—looking for 2 PhD students to start spring next year:

www.gao-unit.com/join-us/

If comp neuro, ML, and AI4Neuro is your thing, or you just nerd out over brain recordings, apply!

I'm at neurips. DM me here / on the conference app or email if you want to meet 🏖️🌮
December 3, 2025 at 9:37 AM
Reposted by Taufik A. Valiante
timothyoleary.bsky.social
We are opening a FACULTY POSITION (tenure track, permanent) in the University of Cambridge at the interface of control and biology, interpreted broadly. Theorists and wet lab quantitative biologists with backgrounds in control, EE, applied math, ... apply by Jan 28!

www.cam.ac.uk/jobs/univers...
University Assistant/Associate Professor in Control Theory and Systems Biology
Applications are invited for a University Assistant/Associate Professorship in the broad area of Control Theory and Systems Biology. The successful candidate will join the Control Group
www.cam.ac.uk
December 3, 2025 at 12:19 PM
Reposted by Taufik A. Valiante
rdgao.bsky.social
hey I'm reposting this for no reason at all today...

www.cell.com/trends/cogni...
Processes and measurements: a framework for understanding neural oscillations in field potentials
Various neuroscientific theories maintain that brain oscillations are important for neuronal computation, but opposing views claim that these macroscale dynamics are ‘exhaust fumes’ of more relevant p...
www.cell.com
November 24, 2025 at 4:39 PM
Reposted by Taufik A. Valiante
natureportfolio.nature.com
A study in Nature Communications identifies BNST theta and prefrontal BNST coherence as intracranial biomarkers predicting depression outcomes after deep brain stimulation. Lower activity predicted better long-term benefit, linking brain circuits to emotional bias and anxiety. 🧪
Prefrontal–bed nucleus of the stria terminalis physiological and neuropsychological biomarkers predict therapeutic outcomes in depression - Nature Communications
This study identifies BNST theta and prefrontal BNST coherence as intracranial biomarkers predicting depression outcomes after DBS. Lower activity predicted better long-term benefit, linking brain circuits to emotional bias and anxiety.
go.nature.com
November 23, 2025 at 5:23 PM
Reposted by Taufik A. Valiante
crania-toronto.bsky.social
It was incredible to be part of #purpleday yesterday! 💜 Each year, this important day continues to grow bigger and stronger, bringing more awareness and support for the 1-in-100 people living with epilepsy.

@kbi-uhn.bsky.social @uhnresearch.bsky.social @tvaliante.bsky.social
March 27, 2025 at 4:29 PM
Reposted by Taufik A. Valiante
mdepitta.bsky.social
Happy to share this work putting forth the first #computational model of #developing #embrionic cortical circuits. Phenomenal team coordination by Fernando Garcia Moreno @achucarro.bsky.social. @kbi-uhn.bsky.social @kcnhub.bsky.social
Evolutionary convergence of sensory circuits in the pallium of amniotes
The amniote pallium contains sensory circuits that are structurally and functionally equivalent, yet their evolutionary relationship remains unresolved. We used birthdating analysis, single-cell RNA a...
www.science.org
February 15, 2025 at 12:54 AM
Reposted by Taufik A. Valiante
jasonhaslam.ca
I’m not “abandoning my diet”; I’m “supporting my country.”
A 210 gram bag of Hawkins Cheesies, made with real Canadian cheddar.
February 7, 2025 at 9:03 PM
Reposted by Taufik A. Valiante
drlaschowski.bsky.social
Save the date! Come learn about how we're using machine learning to reverse-engineer the human brain and build brain-machine interfaces kite-uhn.com/talk/rounds-...

@uoft.bsky.social @bme-uoft.bsky.social @uhnresearch.bsky.social @uhntoronto.bsky.social @kbi-uhn.bsky.social
February 7, 2025 at 3:50 PM
Reposted by Taufik A. Valiante
alleninstitute.org
New brain aging study is out today in Nature

The largest single-cell RNA seq dataset of mouse brain aging reveals incredible insights and could pave the way for future therapies to slow or manage the impacts of the aging process. 🧵 #studyBRAIN
January 1, 2025 at 5:07 PM
Reposted by Taufik A. Valiante
franklandlab.bsky.social
Just bumping this up for those who may have missed earlier announcements-- we have a new PI position in the Neuroscience & Mental Health program here at SickKids. Neural and glial mechanisms in cognition.
Scientist/Senior Scientist – Research Institute, Hospital for Sick Children, University of Toronto – Canadian Association for Neuroscience
can-acn.org
December 27, 2024 at 6:02 PM
Reposted by Taufik A. Valiante
crania-toronto.bsky.social
We are proud to support this trial through our our extensive academic and clinical programs affiliated with @uoft.bsky.social @uhnresearch.bsky.social

bsky.app/profile/uhnt...
uhn.ca University Health Network @uhn.ca · Dec 23
In an interview with The i Paper, #TeamUHN's Dr. Andres Lozano discusses his excitement over UHN's Toronto Western Hospital being selected as the first international site of Neuralink trials.

Read more 👇
bit.ly/4fBI7RQ
'We'll be uploading information to the brain' - the future of Musk's Neuralink
Previous brain implants were bulkier or required cables to protrude from the back of a patient’s head
bit.ly
December 24, 2024 at 2:29 PM
Reposted by Taufik A. Valiante
alleninstitute.org
Congrats to Sam Mestern, Ph.D. student at @westernu.bsky.social, for winning the MapMySpikes challenge! His tool, PatchOTDA, excelled in mapping electrophysiological data to molecular properties. 🧠📈

More on his tool and the MapMySpikes challenge: alleninstitute.org/news/canadia...
Canadian Ph.D. student, Sam Mestern, wins first MapMySpikes challenge
The Allen Institute for Brain Science's MapMySpikes challenge aimed to address a key challenge in neuroscience by making connections between cells' electrical and molecular properties.
alleninstitute.org
December 11, 2024 at 11:09 PM
Reposted by Taufik A. Valiante
uhnresearch.ca
Three UHN research projects have received over $4M through the Ontario Research Fund, part of a $92M investment in Ontario research!

Learn how this funding advances:
▶️#MRI tech
▶️#AI for donor lungs
▶️Muscle & joint #health

Congrats to the awardees!
🔗 www.uhnresearch.ca/news/investi...
Collage of five smiling male researchers of diverse backgrounds with institutional logos at the bottom.
December 10, 2024 at 4:11 PM
Reposted by Taufik A. Valiante
neurovium.bsky.social
Hopfield and Hinton @nobelprize.bsky.social lecture today
John J. Hopfield: Physics is a point of view
Geoffrey Hinton: Boltzmann Machines
www.youtube.com/live/lPIVl5e...
YouTube
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December 8, 2024 at 3:20 PM
tvaliante.bsky.social
Grateful for these two and that they find such joy in one another!! Photo cred @samravaliante.bsky.social
December 6, 2024 at 1:50 PM
tvaliante.bsky.social
Holiday festivities have begun. Grateful for my amazing lab for making each year fun, and exciting!!
December 3, 2024 at 11:41 PM
Reposted by Taufik A. Valiante
mrikasper.bsky.social
Done Christmas Shopping? Or need inspiration what open MRI tools to get for your loved ones? After Black Friday and Cyber Monday, there is 🥁

#MRITogether Tuesday (and Wednesday-Thursday-Friday 😉). There is still time to register for our free online event mritogether.esmrmb.org/24m/registra...
December 2, 2024 at 12:56 AM
Reposted by Taufik A. Valiante
bowang87.bsky.social
Thank you to the global community for citing, sharing, and building on this work! 🙏
Read the paper here: nature.com/articles/s41...

Stay tuned for MedSAM2, set to be released next month, offering enhanced efficiency and accuracy for medical video and 3D image segmentation.
November 27, 2024 at 1:47 AM
Reposted by Taufik A. Valiante
bowang87.bsky.social
thanks @haoyin.bsky.social 🙏🙏
haoyin.bsky.social Hao Yin @haoyin.bsky.social · Nov 20
Dr. Bo Wang is on BlueSky now

@bowang87.bsky.social

Follow him if you don't want to miss the coolest AI-Biomedical development!!!😎
November 20, 2024 at 2:41 AM
Reposted by Taufik A. Valiante
richcompneuro.bsky.social
An early Thanksgiving gift to you all… a new preprint, representing the final piece of my postdoc work at @kbi-uhn.bsky.social @kcnhub.bsky.social @uhnresearch.bsky.social with @tvaliante.bsky.social.

Full description to come next week 😀

#neuroskyence #compneuro

www.biorxiv.org/content/10.1...
H- and m-channel overexpression promotes seizure-like events by impairing the ability of inhibitory neurons to process correlated inputs
Channelopathies affecting h- and m-channels present a paradox in epilepsy research: while both over- and underexpression of these channels can be epileptogenic, channel overexpression does not appear ...
www.biorxiv.org
November 26, 2024 at 2:40 PM
Reposted by Taufik A. Valiante
neurovium.bsky.social
Oh I know this guy. I listen to him all the time. But more importantly, you should see what his colleagues have to say about
"To Keep or Not to Keep"
November 25, 2024 at 3:12 PM