We report the timely detection of a strain of Neisseria gonorrhoeae which was confirmed as a diagnostic escape mutant on the Cepheid Xpert CT/NG assay in England in June 2025. The reason for assay failure was a likely recombination event with Neisseria meningitidis, which removed both assay target sites. Seven historical putative Xpert CT/NG assay diagnostic escape mutants were also identified following subsequent in silico screening of gonococcal genome collections, but currently there is no evidence of widespread circulation.

Ingestion of bromide can lead to a toxidrome known as bromism. While this condition is less common than it was in the early 20th century, it remains important to describe the associated symptoms and r...

The London School of Hygiene & Tropical Medicine (LSHTM) is one of the world’s leading public health universities. Our mission is to improve health and health equity in the UK and worldwide; working i...