Stephan Uphoff
@uphoff.bsky.social
Associate Professor at Oxford Biochemistry. Investigating bacterial DNA Repair and Mutagenesis. Imaging single molecules and single cells.
Reposted by Stephan Uphoff
academic.oup.com/nar/article/... Collaboration with Y. Yamaichi. Killing donor bacteria in conjugation mixes using water enables transcriptomic profiling of early plasmid genes ! Superb tool for studying zygotic induction of these early genes, which include anti-SOS and anti-RM factors. #microsky
Selective elimination of donor bacteria enables global profiling of plasmid gene expression at early stages of conjugation
Abstract. Conjugative plasmids are a major driving force for the dissemination of antimicrobial resistance. During conjugation, plasmid DNA is transferred
academic.oup.com
December 10, 2025 at 6:06 PM
academic.oup.com/nar/article/... Collaboration with Y. Yamaichi. Killing donor bacteria in conjugation mixes using water enables transcriptomic profiling of early plasmid genes ! Superb tool for studying zygotic induction of these early genes, which include anti-SOS and anti-RM factors. #microsky
Reposted by Stephan Uphoff
Independent research fellowships leading to tenured positions at the John Innes Centre.
Repost = nice. Thank you very much!!!
Repost = nice. Thank you very much!!!
Shortlisted candidates will be invited to give a seminar at the Fellows Conference, which will be held on 10 March 2026.
Candidates who win Fellowships will be offered a Tenure Track Group Leader position from the outset, initially for 5 years.
Find out more: www.jic.ac.uk/training-car...
Candidates who win Fellowships will be offered a Tenure Track Group Leader position from the outset, initially for 5 years.
Find out more: www.jic.ac.uk/training-car...
Independent Research Fellowships Leading to Tenured Faculty Positions | John Innes Centre
The John Innes Centre (JIC), is a world leading centre of excellence in plant and microbial sciences based on the Norwich Research Park, UK. We are inviting applications from outstanding researchers…
www.jic.ac.uk
October 3, 2025 at 4:06 PM
Independent research fellowships leading to tenured positions at the John Innes Centre.
Repost = nice. Thank you very much!!!
Repost = nice. Thank you very much!!!
Reposted by Stephan Uphoff
With evidence attached 😊
#BioPhyChrom2025
@biochemsoc.bsky.social @biophychrom.bsky.social
@damelab.bsky.social @vslioy.bsky.social @graingerlab.bsky.social @lauraspagnolo.bsky.social @tamarabasta.bsky.social
#BioPhyChrom2025
@biochemsoc.bsky.social @biophychrom.bsky.social
@damelab.bsky.social @vslioy.bsky.social @graingerlab.bsky.social @lauraspagnolo.bsky.social @tamarabasta.bsky.social
September 18, 2025 at 6:06 AM
Reposted by Stephan Uphoff
Next week, Biophychrom is happening and there’s still time to join us! 👇🏻
One week to go for The Biology & Physics of Chromosomes VII, but there is still time to register!
Join us! 🧬🧬🧬
@biophychrom.bsky.social @biochemsoc.bsky.social @vslioy.bsky.social @graingerlab.bsky.social @damelab.bsky.social
Join us! 🧬🧬🧬
@biophychrom.bsky.social @biochemsoc.bsky.social @vslioy.bsky.social @graingerlab.bsky.social @damelab.bsky.social
September 9, 2025 at 5:13 AM
Next week, Biophychrom is happening and there’s still time to join us! 👇🏻
Reposted by Stephan Uphoff
I forgot to post about this recent paper - exciting work led by @michriscopy.bsky.social showing clearest evidence yet for transertion strongly tethering the bacterial nucleoid to the membrane during fast growth. It was a pleasure to contribute a little 🔬🦠🧫 www.nature.com/articles/s41...
The nucleoid of rapidly growing Escherichia coli localizes close to the inner membrane and is organized by transcription, translation, and cell geometry - Nature Communications
The mechanisms underlying bacterial chromosome configuration are not fully understood. Here, Spahn et al. show that the Escherichia coli nucleoid adopts a condensed, membrane-proximal configuration du...
www.nature.com
May 9, 2025 at 2:37 PM
I forgot to post about this recent paper - exciting work led by @michriscopy.bsky.social showing clearest evidence yet for transertion strongly tethering the bacterial nucleoid to the membrane during fast growth. It was a pleasure to contribute a little 🔬🦠🧫 www.nature.com/articles/s41...
Reposted by Stephan Uphoff
An emotional day today @oxfordbiochemistry.bsky.social where leaders in the cell cycle field gathered to celebrate the life of Bela Novak and the huge impact he had on their work! www.bioch.ox.ac.uk/article/prof...
Professor Bela Novak (1956–2025): A Life of Scientific Discovery in Numbers
It is with profound sorrow that we announce the passing of Professor Béla Novák
www.bioch.ox.ac.uk
May 9, 2025 at 3:36 PM
An emotional day today @oxfordbiochemistry.bsky.social where leaders in the cell cycle field gathered to celebrate the life of Bela Novak and the huge impact he had on their work! www.bioch.ox.ac.uk/article/prof...