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Reposted by Weria Pezeshkian

Markus Deserno @markusdeserno.bsky.social · 12d

I am super excited to announce that we have a tenure-track faculty position in biophysics open in the Department of Physics at Carnegie Mellon! 🧪

Interfolio link: apply.interfolio.com/174360

PLEASE, share widely across the blue skies!

Let me briefly explain what we're looking for:

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Tenure-track Position in Biophysics at Carnegie Mellon University, Department of Physics

Location: Pittsburgh, PA
Open Date: Sep 19, 2025

Description
The Department of Physics at Carnegie Mellon University invites applications for a tenure-track faculty position in biophysics. The appointment is intended to be at the Assistant Professor level, but exceptional candidates at a higher level may also be considered. We seek outstanding candidates with a strong record in cellular and subcellular biophysics. Topics of particular interest include, but are not limited to, uncovering how key characteristics of living systems arise from the interplay between supramolecular cellular structures, how the emergent cellular circuitry defines goals and enables robust decision making, and how metabolic resources are allocated. This encompasses understanding of how information is learned, stored, transduced, and processed across subcellular structures. Applicants with theoretical, data science, or experimental backgrounds within biological physics are encouraged to apply. The ideal candidate will strengthen and extend research programs of current biophysics faculty in the Department of Physics and collaborate with broader life science activities across many departments at CMU and the wider Pittsburgh area.

More details on Interfolio: https://apply.interfolio.com/174360

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Weria Pezeshkian @weria-lab.bsky.social · 21d

A new preprint from my group by my PhD student Adria:
No attraction between proteins, they do not induce curvature, but they cluster on membranes.
One of the reasons why mesoscale modeling matters.
www.biorxiv.org/content/10.1...

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Reposted by Weria Pezeshkian

Siewert-Jan Marrink @cg-martini.bsky.social · Sep 3

Martini on top of the world ! TS2CG as a Membrane Builder | Journal of Chemical Theory and Computation pubs.acs.org/doi/10.1021/...

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Weria Pezeshkian @weria-lab.bsky.social · May 29

New collaborative preprint, Helfrich Monte Carlo Flexible Fitting: physics-based, data-driven cell-scale simulations. By Valentin J. Maurer, Marc Siggel, Jan Kosinski, Julia Mahamid

www.biorxiv.org/content/10.1...

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Weria Pezeshkian @weria-lab.bsky.social · Apr 17

github.com/weria-pezesh...

GitHub - weria-pezeshkian/TS2CG-v2.0: TS2CG version 1.2

TS2CG version 1.2. Contribute to weria-pezeshkian/TS2CG-v2.0 development by creating an account on GitHub.

github.com

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Weria Pezeshkian @weria-lab.bsky.social · Apr 17

New preprint: TS2CG version 2, building and simulating membranes with any shape and lateral organisation. We got Martini Globe, Martini Möbius strip and again mitochondrion.
www.biorxiv.org/content/10.1...
@cg-martini.bsky.social @janstevens.bsky.social @fabianschuhmann.bsky.social

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Reposted by Weria Pezeshkian

Rommie Amaro @rommieamaro.bsky.social · Mar 14

interesting preprint from Weria Pezeshkian on general material properties of membranes

Lateral tension can lead to membrane neck constriction at low tension & dilation at high tensions

relevant to nuclear pores, ER, mitochondria, Golgi etc

www.biorxiv.org/content/10.1...

Visualisation of the necks‘ behaviour for six (right) necks in PBC at bending rigidity of 𝜅 = 10 𝑘𝐵𝑇. This illustrates a second transition point or region in the six-neck-system, facilitated by successive dilation of more than one neck.

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Weria Pezeshkian @weria-lab.bsky.social · Mar 14

A new preprint from my group by my PhD student Beatrice Geiger. The main message: increasing tension can lead to constriction of the pore in nuclear envelope like shapes, and for larger tension, the pore dilate.

www.biorxiv.org/content/10.1...

Complex mechanical response of stomatocyte morphology: Implications for the nuclear envelope.

Among the fascinating shapes that biomembranes exhibit are stomatocytes, found for example in nuclear membranes and open autophagosomes. These morphologies, characterised by a high topological genus, ...

www.biorxiv.org

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Weria Pezeshkian @weria-lab.bsky.social · Dec 10

The event concluded with a workshop on FreeDTS, but I didn’t have time to take a selfie.

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Weria Pezeshkian @weria-lab.bsky.social · Dec 10

The final short talk by Adria Bravo Vidal my PhD student,
On the sampling of simulations of membrane shape

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Weria Pezeshkian @weria-lab.bsky.social · Dec 10

Now active system. Dr Dmitry Fedosov (Forschungszentrum Jülich GmbH Wilhelm Johnen StraßeStraße, Jülich Germany) is talking about:
Simulations of active vesicles

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Weria Pezeshkian @weria-lab.bsky.social · Dec 10

Short talk by Tatiana Morozova, CNRS/Institut Pasteur,
Role of the sequnce length in the coil-to-globule transition of elastin-like polypeptides

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Weria Pezeshkian @weria-lab.bsky.social · Dec 10

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Weria Pezeshkian @weria-lab.bsky.social · Dec 10

Second day, exciting talk by Prof. Cecilia Clementi (@cecclementi.bsky.social) Clementi from Free University of Berlin Berlin, Germany.

Navigating protein landscapes with a machine learned transferable coarse-grained model

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Weria Pezeshkian @weria-lab.bsky.social · Dec 9

Great first day of the workshop! Excellent participation both onsite and online. Tomorrow, we start again at 9:00 a.m. CET with a talk from Prof. Cecilia Clementi.

Weria Pezeshkian @weria-lab.bsky.social · Dec 9

And the final talk (short talk) by Leonhard Starke (Aarhus University)
Pore formation in complex biological membranes

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Weria Pezeshkian @weria-lab.bsky.social · Dec 9

Ali Asghar Hakami Zanjani from University of Southern Denmark.

Advanced Sampling Methodology for Investigating Early-Stage Amyloid Aggregation Structures.

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Weria Pezeshkian @weria-lab.bsky.social · Dec 9

After a small break enforced by the projector, Lorena Zuzic from Aarhus University is talking about PINning down the elevator-type mechanism of auxin transport

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Weria Pezeshkian @weria-lab.bsky.social · Dec 9

(Short talk) Dimitrios Kolokouris from University of Copenhagen, is talking about

Investigating the role of cholesterol in regulating the SLC7 family of amino acid transporters

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Weria Pezeshkian @weria-lab.bsky.social · Dec 9

Now we have a 4 short talks. First, Fabian Schuhmann from my group is talking about

An integrative MD model reveals protein complexes and protein distribution in mitochondria

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Reposted by Weria Pezeshkian

Brian Ratnasinghe @brianrat.bsky.social · Dec 9

Dr. Paulo Cesar Telles de Souza's Workshop on Mastering Parameterization in Martini3 is happening right now. Absolutely one of the most insightful talks I've attended.

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Weria Pezeshkian @weria-lab.bsky.social · Dec 9

Now Prof. Siewert Jan Marrink from University of Groningen Groningen, The Netherlands.
Simulating entire cells with Martini

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Weria Pezeshkian @weria-lab.bsky.social · Dec 9

and finally the first workshop by Prof. Kresten Lindorff-Larsen from University of Copenhagen.
Combining experiments and simulations: theory and practical examples for disordered proteins

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Weria Pezeshkian @weria-lab.bsky.social · Dec 9

First short talk by Eva Smorodina from University of Oslo.
Structural modeling of antibody variant epitope specificity with complementary experimental and computational techniques.

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Weria Pezeshkian @weria-lab.bsky.social · Dec 9

First talk by Prof. Franca Fraternali from University College London. Uncovering antibody sequences and structures, their assembly and their conformational flexibility!

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