Yoana Estrada Reyes
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yoanaestradar.bsky.social
Yoana Estrada Reyes
@yoanaestradar.bsky.social
PhD, interested in: PFC, BLA, 5-HT and Reversal Learning 🇲🇽
Reposted by Yoana Estrada Reyes
Thrilled this is out, led by former PD Cameron Ogg (now with her own lab at @rhodescollege.bsky.social!). It was a driven by a desire to see, in real-time, how LC activity/NE release influences downstream targets in behaving animals. SO hard to do, but Cameron did it! www.cell.com/cell-reports...
Locus coeruleus norepinephrine neurons facilitate orbitofrontal cortex remapping and behavioral flexibility
Ogg et al. use in vivo imaging techniques to record activity in the locus coeruleus (LC) and the orbitofrontal cortex (OFC) during a reversal learning task in freely moving rodents. They show that man...
www.cell.com
December 15, 2025 at 2:47 PM
Reposted by Yoana Estrada Reyes
Serotonin Engages Divergent 5-HT Receptor Pathways for Cell Type-Resolved Modulation of Prefrontal Layer 5 Microcircuits
www.biorxiv.org/content/10.6...
www.biorxiv.org
December 9, 2025 at 11:29 AM
Reposted by Yoana Estrada Reyes
It's all about beta, baby!
Cerebellar-cortical beta oscillations emerge as a predictive signal facilitating the stability of behavioral performance
www.cell.com/current-biol...
#neuroscience
Cerebellar-cortical beta oscillations emerge as a predictive signal facilitating the stability of behavioral performance
Bracco et al. show that pre-movement beta oscillations emerge in a cerebello-cortical network as the environment becomes predictable and outcomes stabilize. The evolution of these oscillations predict...
www.cell.com
December 18, 2025 at 3:11 PM
Reposted by Yoana Estrada Reyes
Hippocampal input-driven plasticity of prefrontal interneurons reveals a circuit basis for impaired spatial working memory. https://www.biorxiv.org/content/10.1101/2025.07.21.665987v1
July 24, 2025 at 8:15 AM
Reposted by Yoana Estrada Reyes
Reposted by Yoana Estrada Reyes
Cortical Serotonin Type 2A Receptor Activation Shields Episodic-like Memories from Retroactive Interference in Rodents
www.biorxiv.org/content/10.1...
Cortical Serotonin Type 2A Receptor Activation Shields Episodic-like Memories from Retroactive Interference in Rodents
The acquisition of temporally proximate information can impair the brain’s ability to consolidate earlier experiences, resulting in retroactive interference (RI). Recognition-based behavioral paradigm...
www.biorxiv.org
July 24, 2025 at 11:55 AM
Reposted by Yoana Estrada Reyes
5-HT-mediated depolarization of OFC PV neurons occurs via activation of 2A, not 2C, receptors. And 2A antagonism works similarly in males and females www.nature.com/articles/s41...
Absence of sex differences in serotonergic control of orbitofrontal cortex neuronal activity - Scientific Reports
Scientific Reports - Absence of sex differences in serotonergic control of orbitofrontal cortex neuronal activity
www.nature.com
July 21, 2025 at 2:28 PM
Reposted by Yoana Estrada Reyes
Check out the new Handbook of Electrophysiology that covers all kinds of ways to record activity! Great working with @drewbheadley.bsky.social on standard equipment you need for in vivo physiology. Edited by @scimemia.bsky.social @ianduguid.bsky.social and @nwanaverbecq.bsky.social
New standard electrophysiology methods text just released! Proud to have contributed a chapter with @elikhtik.bsky.social

www.worldscientific.com/worldscibook...
The Handbook of Electrophysiology
www.worldscientific.com
May 13, 2025 at 5:30 PM
Reposted by Yoana Estrada Reyes
Molecular dynamics study of differential effects of serotonin-2A-receptor (5-HT2AR) modulators
www.biorxiv.org/content/10.1...
Molecular dynamics study of differential effects of serotonin-2A-receptor (5-HT2AR) modulators
The serotonin-2A receptor (5-HT2AR) is an interesting target for drug design in the context of antidepressants that might have a rapid onset of action and/or be effective in treatment-resistant cases....
www.biorxiv.org
April 1, 2025 at 10:01 AM
Reposted by Yoana Estrada Reyes
Restoring Oscillatory Dynamics in Alzheimer’s Disease: A Laminar Whole-Brain Model of Serotonergic Psychedelic Effects
www.biorxiv.org/content/10.1...
www.biorxiv.org
April 1, 2025 at 10:04 AM
Reposted by Yoana Estrada Reyes
Reposted by Yoana Estrada Reyes
Rhythms and communication in the brain
doi.org/10.1016/j.ti...
March 11, 2025 at 8:30 PM
Reposted by Yoana Estrada Reyes
Serotonin signaling in the rat prefrontal cortex is required for Retrieval-Induced Forgetting
www.biorxiv.org/content/10.1...
Serotonin signaling in the rat prefrontal cortex is required for Retrieval-Induced Forgetting
Forgetting is a ubiquitous phenomenon that is actively promoted in many species. The act of remembering some experiences can cause the forgetting of others in both humans and rats. We previously found...
www.biorxiv.org
March 10, 2025 at 12:24 PM
Reposted by Yoana Estrada Reyes
Persistent representation of a prior schema in the orbitofrontal cortex facilitates learning of a conflicting schema https://www.biorxiv.org/content/10.1101/2025.02.28.640679v1
March 1, 2025 at 11:17 AM
Reposted by Yoana Estrada Reyes
Multiple methods for assessing learning and memory in Drosophila melanogaster demonstrates the highly complex, context-dependent genetic underpinnings of cognitive traits https://www.biorxiv.org/content/10.1101/2025.02.26.640179v1
March 1, 2025 at 11:33 AM