Chris MacDonald
@yorkyeast.bsky.social
430 followers 370 following 40 posts
Cell biologist working on membrane trafficking at the University of York. https://yorkyeast.wixsite.com/yorkyeast
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yorkyeast.bsky.social
@mark-morgan.bsky.social kicking off NECB forum 2025 in Liverpool, funded by @bscb-official.bsky.social and external sponsors.

Great schedule lined up in a really
cool location - talks and posters presented in the Victoria Gallery & Museum 👌
Reposted by Chris MacDonald
bscb-official.bsky.social
We are sponsoring the North of England Cell Biology Forum in Liverpool on 18th Sept

Register and submit your abstracts here:

markmorgan60.wixsite.com/necb2025
yorkyeast.bsky.social
Per Ljungdahl kicking off the 40th SMYTE meeting in beautiful Stockholm yesterday 😃

Programme looks brilliant, ready for a few days immersed in yeast transport 🤓
Reposted by Chris MacDonald
fariatrypslab.bsky.social
How do parasites strategically organise their genomes to influence gene expression? If you’re curious, check our latest review in @cp-trendsparasitol.bsky.social !

@biologyatyork.bsky.social @ybri-uoy.bsky.social @pasteur.fr

www.sciencedirect.com/science/arti...
Reposted by Chris MacDonald
richardsever.bsky.social
bioRxiv bat signal going up. We have a big backlog of submissions. If any affiliates have time to do some screening, we (and all the authors) would be immensely grateful! 🙏
yorkyeast.bsky.social
I’ll be presenting this work (and a bunch of unpublished data) at 2.45pm at the #yeast2025 conference 🤓

This collaboration with @merusadhu.bsky.social has also benefitted from the meeting, as we planned more experiments on the river last night 👌
Reposted by Chris MacDonald
gautamdey.bsky.social
1 month to abstract deadline for the first cell biology of the nucleus meeting at @embl.org in many years - organised by the stellar @luskinglab.bsky.social @sarawickstrom.bsky.social Tom Quail & Simone Koehler

Tons of open slots, invited and selected speakers all get 20 mins ❤️

#EESNucleus
yorkyeast.bsky.social
I have no answer - too many cool s since things happening!?

We need to remedy, I have a meeting over lunch but will be about for posters
yorkyeast.bsky.social
So lovely to connect with the inimitable Terry Cooper again at #yeast2025 - who’s just gearing up to present after a gruelling journey to the meeting!

🙌🙌🙌
yorkyeast.bsky.social
As one might expect, standing room only for Sir Paul Nurse keynote seminar at #yeast2025 in Paris this evening.

👏 👏 👏
Reposted by Chris MacDonald
jcellsci.bsky.social
Kamilla Laidlaw, Hatwan Nadir, Chris MacDonald @yorkyeast.bsky.social and team @biologyatyork.bsky.social discover that killer toxin K28 resistance in yeast relies on COG complex-mediated trafficking of Ktd1.
journals.biologists.com/jcs/article/...
Article: journals.biologists.com/jcs/article/...
Microscopy images showing that correct localisation of either Ktd1 or Snc1 requires the COG complex.
Reposted by Chris MacDonald
ijayas.bsky.social
Essay mills shamelessly advertising on the academia feed. CC @keithwilson.eu
yorkyeast.bsky.social
Travelling to my first ICYGMB meeting #yeast2025 in Paris - the programme looks amazing.

premc.org/yeast2025/
Yeast 2025 - PremC
premc.org
Reposted by Chris MacDonald
neurochicano.bsky.social
go.bsky.app/8zZNEGV

Great resource to connect early career folks with more senior scientists looking to hire postdocs! 🧪
yorkyeast.bsky.social
We bought a shaking incubator for new pathogenic yeast work, but the tray came with holes lacking threads 😒

Luckily, Mark Bentley from our @biologyatyork.bsky.social workshop is a legend - he trimmed down the rack and secured it to the tray.

🔩🪛🙏🏼
Shaking incubator with lid open to display rack and mat for adding culture tubes
Reposted by Chris MacDonald
acartmell47.bsky.social
Happy to have this work on the effectiveness of sulfamate based inhibitors on carbohydrate sulfatases out in @pnas.org www.pnas.org/doi/10.1073/pnas. #glycotime

The summary is: Current sulfatase inhibitor technology is not effective on S1 carbohydrate sulfatases of the human colonic microbiota.
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
yorkyeast.bsky.social
I spoke with authors/reviewers that had been part of the pilot during the biologists@100 meeting - they were extremely positive about the process.

We also had great first experience with @biologyopen.bsky.social last year.

Only issue with the model is mechanisms to cover APCs are vanishing.
peiferlabunc.bsky.social
Publishing scientific papers is an obstacle course. There are many aspects to this but lengthy review times are one. That's why I am very excited about the new initiative @biologyopen.bsky.social, @biologists.bsky.social open access journal: Fast & Fair 1/n 🧪
journals.biologists.com/bio/pages/fa...
Reposted by Chris MacDonald
guijacquemet.bsky.social
- A postdoc to work on cancer extravasation (4-year project).
- A postdoc help in completing Filopodia-related lab projects (2-year).
- Multiple Marie Curie postdoc positions that will open in the fall.
- We will open a 5-year position to cover my teaching (70% research and 30% teaching).
guijacquemet.bsky.social
Are you looking for a postdoc?
I will be looking for 2-4 people after the summer to join the lab !!
Do not hesitate to reach out and disseminate !!
yorkyeast.bsky.social
lol, not sure - or maybe trying to make sure I didn’t come back and try an experiment.

I think the was a collaboration between Zoe Ingold and James Fox 🤣
yorkyeast.bsky.social
Returned from the UK-Japan Frontiers of Science conference to be confronted with this terrifying effigy on my lab bench!
Reposted by Chris MacDonald
atomicvirology.bsky.social
Q for the hive-mind 🧠: What transfection reagents do people like for big constructs these days? (I am thinking #HSV encoding BACs, ~170 kb). We've recently had poor performance with Trans-IT LT1 and Lipofectamine 2000, our two go-tos. Target cells are U2OS. Suggestions or RTs greatly appreciated 🙏
yorkyeast.bsky.social
The UK-Japan frontiers of science meeting @royalsociety.org is this week - amazing line up of speakers covering very broad research themes 😀
Reposted by Chris MacDonald
grahamlab-vandy.bsky.social
As April comes to a close, we wanted to share updates for the first quarter of 2025!!