#Plasmalogen
🧠💓 Functional lipidomics in action!
HL-1 cardiomyocytes recorded on multi-electrode arrays (MEA) show coordinated waves of spontaneous electrical activity — a window into how lipid remodeling affects cardiac excitability.
#Lipidomics #BarthSyndrome #Cardiolipin #Plasmalogen #Mitochondria #MEA
October 30, 2025 at 5:03 PM
1/ Prodrome Glia is part of the @remissionbiome protocol. Plasmalogen supplements are some of the most widely used supplements in our community. If you already use prodrome products or plan to discuss with your healthcare team, you can save money and give back to our organization at the same time!
May 20, 2025 at 9:25 PM
📝 New preprint! We trace the origin of the plasmalogen biosynthesis pathway.

🧬 Phylogenetic and functional analyses suggest eukaryotes acquired it via HGT from Myxobacteria, with major lineage-specific differences.

✨Great collaboration between our group at @UMU and @multicellgenome.bsky.social
October 22, 2025 at 9:21 AM
Novel plasmalogen derivative KIT-13 restores neurological function in a mouse model of Rett syndrome by reducing neuroinflammation and restoring mitochondrial function https://www.biorxiv.org/content/10.1101/2025.06.11.656246v1
June 13, 2025 at 1:15 AM
1/ Prodrome Glia is part of the @remissionbiome protocol. Plasmalogen supplements are widely used in our community. If you already use Prodrome products or plan to discuss with your healthcare team, you can save money and give back to our non-profit at the same time!
June 5, 2025 at 11:30 PM
🎉 Excited to share that our ARUK Pilot Grant has been funded! 🚀

Our project will explore plasmalogen lipid function in human iPSC-neurons to better understand synaptic dysfunction in Alzheimer’s Disease.

🧠💡 Stay tuned for updates!
@alzheimersresearchuk.org #NeuroLipidomics #Alzheimers #Plasmalogen
April 3, 2025 at 1:47 PM
Novel plasmalogen derivative KIT-13 restores neurological function in a mouse model of Rett syndrome by reducing neuroinflammation and restoring mitochondrial function https://www.biorxiv.org/content/10.1101/2025.06.11.656246v1
June 13, 2025 at 1:15 AM
1/ #Prodrome Glia is part of the @remissionbiome protocol. Plasmalogen supplements are some of the most widely used supplements in our community. If you already use prodrome products or plan to discuss with your healthcare team, you can save money and give back to our organization at the same time!
June 11, 2025 at 11:09 AM
Plasmalogen-Independent Neuroprotection: Synthetic alkyl ether lipids activate signaling to mitigate neuroinflammation and enhance cognitive function https://www.biorxiv.org/content/10.64898/2025.12.08.693101v1
December 11, 2025 at 7:15 PM
Plasmalogen oxidation induces the generation of excited molecules and electrophilic lipid species https://www.biorxiv.org/content/10.1101/2024.02.22.581635v1
Plasmalogen oxidation induces the generation of excited molecules and electrophilic lipid species https://www.biorxiv.org/content/10.1101/2024.02.22.581635v1
Plasmalogens are glycerophospholipids with a vinyl-ether linkage at the sn-1 position of the glycero
www.biorxiv.org
February 23, 2024 at 2:48 AM
Plasmalogen-Independent Neuroprotection: Synthetic alkyl ether lipids activate signaling to mitigate neuroinflammation and enhance cognitive function #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.64898/2025.12.08.693101v1
December 12, 2025 at 8:02 AM
Plasmalogen oxidation induces the generation of excited molecules and electrophilic lipid species https://www.biorxiv.org/content/10.1101/2024.02.22.581635v1
Plasmalogen oxidation induces the generation of excited molecules and electrophilic lipid species https://www.biorxiv.org/content/10.1101/2024.02.22.581635v1
Plasmalogens are glycerophospholipids with a vinyl-ether linkage at the sn-1 position of the glycero
www.biorxiv.org
February 23, 2024 at 2:48 AM
Origin of Eukaryotic Plasmalogen Biosynthesis by Horizontal Gene Transfer from Myxobacteria https://www.biorxiv.org/content/10.1101/2025.10.10.681575v1
October 11, 2025 at 1:32 AM
[BioRxiv] Plasmalogen-Independent Neuroprotection: Synthetic alkyl ether lipids activate signaling to mitigate neuroinflammation and enhance cognitive function

https://doi.org/10.64898/2025.12.08.693101

#neurodegeneration #biorxiv #neuroprotective #Alzheimers
BioRxiv Article
doi.org
December 12, 2025 at 12:27 AM
Plasma plasmalogen levels and risk of lymph node positive breast cancer https://www.biorxiv.org/content/10.64898/2025.12.11.693510v1
December 15, 2025 at 4:47 PM
"Three-quarters of the lipids in the deep-sea comb jellies were plasmalogens, a type of curved lipid that is rarer in surface animals..

Plasmalogen lipids are also found in the human brain, and their role in deep-sea membranes could help explain aspects of cell signaling." #ufosky
The Cellular Secret to Resisting the Pressure of the Deep Sea | Quanta Magazine
Cell membranes from comb jellies reveal a new kind of adaptation to the deep sea: curvy lipids that conform to an ideal shape under pressure.
www.quantamagazine.org
February 8, 2025 at 1:13 PM
1/ Prodrome Glia is part of the @remissionbiome protocol. Plasmalogen supplements are widely used in our community. If you already use Prodrome products or plan to discuss with your healthcare team, you can save money and give back to our non-profit at the same time!
May 29, 2025 at 11:30 PM
#Alkylglycerol feeding ad libitum for 16 weeks in this #heartfailure 🐁model restored #plasmalogen lipids & successfully sustained🫀morphology & function in♂️but not♀️
December 11, 2024 at 9:04 AM
Indeed! Very nice collaboration with @irenedelrey.bsky.social @sebasn1.bsky.social @konsmitsi.bsky.social @jtrinidad13.bsky.social Montse Elias, Padhu & others to decipher the origin of the #plasmalogen biosynthesis pathway. @ibe-barcelona.bsky.social @icreacommunity.bsky.social @csic.es
November 12, 2025 at 7:05 PM
Special phospholipids called #Plasmalogens are common in the cell membranes of deep sea #combjellies (ctenophores.) The angled shape of plasmalogen molecules maintains membrane fluidity by making them highly resistant to deformation and close packing under pressure
September 16, 2024 at 8:17 AM
Plasmalogen-Independent Neuroprotection: Synthetic alkyl ether lipids activate signaling to mitigate neuroinflammation and enhance cognitive function https://www.biorxiv.org/content/10.64898/2025.12.08.693101v1
December 11, 2025 at 7:15 PM