hEDTA and EDDS as sustainable and harmless alternatives to NTA as trace metal chelators in Methanothermobacter marburgensis cultivation
#microbiology #methanogens #extremophiles
@springer.springernature.com
link.springer.com/article/10.1...
#microbiology #methanogens #extremophiles
@springer.springernature.com
link.springer.com/article/10.1...
hEDTA and EDDS as sustainable and harmless alternatives to NTA as trace metal chelators in Methanothermobacter marburgensis cultivation - Extremophiles
Extremophiles - The thermophilic methanogenic archaea Methanothermobacter spp. are applied as archaeal cell factories in industrial processes for methane production. Recently, secretion of...
link.springer.com
November 25, 2025 at 12:00 PM
hEDTA and EDDS as sustainable and harmless alternatives to NTA as trace metal chelators in Methanothermobacter marburgensis cultivation
#microbiology #methanogens #extremophiles
@springer.springernature.com
link.springer.com/article/10.1...
#microbiology #methanogens #extremophiles
@springer.springernature.com
link.springer.com/article/10.1...
Professor Rachel Codd, who has travelled from Australia to share her exciting research with us at the #ChemSciSymposium, introduces her 'obsession with chelators'.
November 19, 2025 at 10:27 AM
Professor Rachel Codd, who has travelled from Australia to share her exciting research with us at the #ChemSciSymposium, introduces her 'obsession with chelators'.
They need all the chelators to sell to parents of autistic kids.
April 11, 2025 at 10:22 PM
They need all the chelators to sell to parents of autistic kids.
Describing the role and mechanisms of metal ions in brain #homeostasis and #Neurodegenerative diseases, with a discussion on the therapeutic implications of metal ion chelators in neurodegenerative diseases. #medsky
#OpenAccess: doi.org/10.1038/s413...
#OpenAccess: doi.org/10.1038/s413...
August 24, 2025 at 4:30 AM
Describing the role and mechanisms of metal ions in brain #homeostasis and #Neurodegenerative diseases, with a discussion on the therapeutic implications of metal ion chelators in neurodegenerative diseases. #medsky
#OpenAccess: doi.org/10.1038/s413...
#OpenAccess: doi.org/10.1038/s413...
They had a revolving door with the EPA since forever. Now they probably run it. Even a decade ago, they were spending millions to tar researchers who were investigating chelators and their role in interrupting brain function.
October 31, 2025 at 10:18 PM
They had a revolving door with the EPA since forever. Now they probably run it. Even a decade ago, they were spending millions to tar researchers who were investigating chelators and their role in interrupting brain function.
I mean, could someone try slipping chelators into viagra and testosterone?
May 6, 2025 at 4:45 AM
I mean, could someone try slipping chelators into viagra and testosterone?
The modified lines showed higher levels of mineral chelators nicotianamine and 2'-deoxymugineic acid, resulting in increased accumulation of essential minerals like iron and zinc.
November 13, 2025 at 11:10 PM
The modified lines showed higher levels of mineral chelators nicotianamine and 2'-deoxymugineic acid, resulting in increased accumulation of essential minerals like iron and zinc.
Why are iron chelators not as effective as artemisinin in killing malaria parasites? #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-5925851/latest
https://www.researchsquare.com/article/rs-5925851/latest
March 1, 2025 at 4:08 PM
Why are iron chelators not as effective as artemisinin in killing malaria parasites? #SingleCell 🧪🧬🖥️
https://www.researchsquare.com/article/rs-5925851/latest
https://www.researchsquare.com/article/rs-5925851/latest
Very happy to share our last work (and 1st article as last author) that is now available online @ChemCommun
A caged TBTA ligand that allow for CuAAC reactions in the presence of bulky Cu(I)-chelators @ism2_fr
@INC_CNRS
pubs.rsc.org/en/content/art…
A caged TBTA ligand that allow for CuAAC reactions in the presence of bulky Cu(I)-chelators @ism2_fr
@INC_CNRS
pubs.rsc.org/en/content/art…
January 20, 2025 at 3:25 PM
Very happy to share our last work (and 1st article as last author) that is now available online @ChemCommun
A caged TBTA ligand that allow for CuAAC reactions in the presence of bulky Cu(I)-chelators @ism2_fr
@INC_CNRS
pubs.rsc.org/en/content/art…
A caged TBTA ligand that allow for CuAAC reactions in the presence of bulky Cu(I)-chelators @ism2_fr
@INC_CNRS
pubs.rsc.org/en/content/art…
Chelating agents make minerals more soluble. The data suggests that you'd have to use 1000x more than a normal iron phosphate dose for the chelators to have any impacts on earthworms, but again, I stay on the safe side! The chelator in my iron phosphate is EDDS, which is very biodegradable.
May 31, 2023 at 8:48 PM
Chelating agents make minerals more soluble. The data suggests that you'd have to use 1000x more than a normal iron phosphate dose for the chelators to have any impacts on earthworms, but again, I stay on the safe side! The chelator in my iron phosphate is EDDS, which is very biodegradable.
Jones, K. G.; David, T.; Loula, M.; Matějová, S.; Blahut, J.; Filimoněnko, A.; Litecká, M.; Rohlíček, J.; Böserle, J.; Polasek, M. Macrocyclic Chelators for Aqueous Lanthanide Separations via Precipitation: Toward Sustainable Recycling of Rare-Earths from NdFeB Magnets. JASC. doi.org/10.1021/jacs...
Macrocyclic Chelators for Aqueous Lanthanide Separations via Precipitation: Toward Sustainable Recycling of Rare-Earths from NdFeB Magnets
Rare-earth elements (REEs) are critical materials in modern industry, but their production has a significant environmental footprint. Environmentally friendly separation methods would enable efficient...
doi.org
July 1, 2025 at 10:04 AM
Jones, K. G.; David, T.; Loula, M.; Matějová, S.; Blahut, J.; Filimoněnko, A.; Litecká, M.; Rohlíček, J.; Böserle, J.; Polasek, M. Macrocyclic Chelators for Aqueous Lanthanide Separations via Precipitation: Toward Sustainable Recycling of Rare-Earths from NdFeB Magnets. JASC. doi.org/10.1021/jacs...
Chelators are unsung skincare heroes that neutralize harmful metal ions, boosting product effectiveness and keeping your skin radiant. #SkincareSecrets - buff.ly/qD4O08r
June 24, 2025 at 1:31 PM
Chelators are unsung skincare heroes that neutralize harmful metal ions, boosting product effectiveness and keeping your skin radiant. #SkincareSecrets - buff.ly/qD4O08r
4/ We made a reporter cell line with the zft 3'UTR, containing the putative IRE, downstream tdTomato. Our reporter cell line responded to iron chelation in a dose dependent way, but was not responsive to chelators for Zinc or Copper. So, the zft UTR is sufficient to confer iron responsiveness.
a light bulb is lit up in a dark room with the word sylvania on the back
ALT: a light bulb is lit up in a dark room with the word sylvania on the back
media.tenor.com
February 5, 2025 at 11:50 AM
4/ We made a reporter cell line with the zft 3'UTR, containing the putative IRE, downstream tdTomato. Our reporter cell line responded to iron chelation in a dose dependent way, but was not responsive to chelators for Zinc or Copper. So, the zft UTR is sufficient to confer iron responsiveness.
Novel Role of Copper Transporter CTR1 and Therapeutic Potential of Copper Chelators in Retinal Ischemia-Reperfusion Injury https://www.biorxiv.org/content/10.1101/2025.05.17.654687v1
May 21, 2025 at 2:30 PM
Novel Role of Copper Transporter CTR1 and Therapeutic Potential of Copper Chelators in Retinal Ischemia-Reperfusion Injury https://www.biorxiv.org/content/10.1101/2025.05.17.654687v1
Proteinaceous Metal-Binding Eph-Ephrin Tetramerization is Modulated by Copper and Chelators https://www.biorxiv.org/content/10.64898/2025.12.08.693004v1
December 11, 2025 at 5:16 PM
Proteinaceous Metal-Binding Eph-Ephrin Tetramerization is Modulated by Copper and Chelators https://www.biorxiv.org/content/10.64898/2025.12.08.693004v1
Have you seen this latest Chemical Science paper from Rachel Codd and co-workers?
"An elastic siderophore synthetase and rubbery substrates assemble multimeric linear and macrocyclic hydroxamic acid metal chelators"
Read, free: doi.org/10.1039/D4SC...
#ChemSky
"An elastic siderophore synthetase and rubbery substrates assemble multimeric linear and macrocyclic hydroxamic acid metal chelators"
Read, free: doi.org/10.1039/D4SC...
#ChemSky
An elastic siderophore synthetase and rubbery substrates assemble multimeric linear and macrocyclic hydroxamic acid metal chelators
The trihydroxamic acid bacterial siderophore desferrioxamine B (DFOB, 1) produced by the DesABCD biosynthetic cluster coordinates metals beyond Fe(iii), which identifies potential to modify this chelator type to broaden metal sequestration and/or delivery applications. Rather than producing discrete chelator
doi.org
March 14, 2025 at 9:55 AM
Have you seen this latest Chemical Science paper from Rachel Codd and co-workers?
"An elastic siderophore synthetase and rubbery substrates assemble multimeric linear and macrocyclic hydroxamic acid metal chelators"
Read, free: doi.org/10.1039/D4SC...
#ChemSky
"An elastic siderophore synthetase and rubbery substrates assemble multimeric linear and macrocyclic hydroxamic acid metal chelators"
Read, free: doi.org/10.1039/D4SC...
#ChemSky
Both of these papers were highlighted as covers on the journal!
November 19, 2025 at 11:25 AM
Both of these papers were highlighted as covers on the journal!
Is 'wing beating tremor' always present in Wilson's disease? Nope. Let's all gear up as the countdown to @movedisorder Aspen movement course begins this month. Will we start developing 'smarter chelators' with less side effects? This group in 2024 is talking about a pro-chelator
November 25, 2024 at 11:11 AM
Is 'wing beating tremor' always present in Wilson's disease? Nope. Let's all gear up as the countdown to @movedisorder Aspen movement course begins this month. Will we start developing 'smarter chelators' with less side effects? This group in 2024 is talking about a pro-chelator
#ChemSky This Preprint by @sophieguti.bsky.social has got it all: Natural Product synthesis, Chelators, Ln, Curium luminescence, mass spec methods, bacteria! doi.org/10.26434/che... Comparative Binding Studies of the Chelators Methylolanthanin and Rhodopetrobactin B to Lanthanides and Ferric Iron.🧪🧵
December 3, 2024 at 3:54 PM
#ChemSky This Preprint by @sophieguti.bsky.social has got it all: Natural Product synthesis, Chelators, Ln, Curium luminescence, mass spec methods, bacteria! doi.org/10.26434/che... Comparative Binding Studies of the Chelators Methylolanthanin and Rhodopetrobactin B to Lanthanides and Ferric Iron.🧪🧵
Importantly, combining copper chelators with anti-PD-1 treatment effectively suppressed tumor growth, and high SLC31A1 levels were associated with non-response to anti-PD-1 therapy.
August 3, 2025 at 1:41 PM
Importantly, combining copper chelators with anti-PD-1 treatment effectively suppressed tumor growth, and high SLC31A1 levels were associated with non-response to anti-PD-1 therapy.
Our review paper on mitochondria-targeted iron and copper chelators is out. 🧪
Chelating mitochondrial iron and copper: Recipes, pitfalls and promise
Iron and copper chelation therapy plays a crucial role in treating conditions associated with metal overload, such as hemochromatosis or Wilson’s dise…
www.sciencedirect.com
May 21, 2024 at 11:47 AM
Our review paper on mitochondria-targeted iron and copper chelators is out. 🧪
Finally, we use ion mobility spectrometry-mass spectrometry to investigate the RPB B and MLL complexation in the gas phase with Fe3+ and #lanthanides. Our results challenge the classical siderophore-like Ln-uptake (via simple solubilisation) through MLL
December 3, 2024 at 3:55 PM
Finally, we use ion mobility spectrometry-mass spectrometry to investigate the RPB B and MLL complexation in the gas phase with Fe3+ and #lanthanides. Our results challenge the classical siderophore-like Ln-uptake (via simple solubilisation) through MLL
Some of those toxins especially the ones that are found in forever pesticides like glyphosate are known to be mineral chelators, thus not only are they themselves potentially toxic but they inhibit your body from uptaking the minerals that would be present in the grains where glyphosate is present
January 26, 2025 at 1:14 AM
Some of those toxins especially the ones that are found in forever pesticides like glyphosate are known to be mineral chelators, thus not only are they themselves potentially toxic but they inhibit your body from uptaking the minerals that would be present in the grains where glyphosate is present
Indeed. Here in Europe, there’s actually an Austrian company called Claro that produces an “all-in-one” powder, meaning it also contains ingredients to handle hard water (i.e. phosphonates, chelators, polymers). Might be a possible solution for Americans having problems with simple powder.
November 4, 2025 at 9:55 PM
Indeed. Here in Europe, there’s actually an Austrian company called Claro that produces an “all-in-one” powder, meaning it also contains ingredients to handle hard water (i.e. phosphonates, chelators, polymers). Might be a possible solution for Americans having problems with simple powder.
I'm not familiar with any similar nutritional immune response involving zinc though.
However, limiting zinc availability to sensitize bacteria to antibiotics isn't a novel idea. Here's 2020 paper about using chelators to sensitize bacteria to carbapenems. www.liebertpub.com/doi/10.1089/...
However, limiting zinc availability to sensitize bacteria to antibiotics isn't a novel idea. Here's 2020 paper about using chelators to sensitize bacteria to carbapenems. www.liebertpub.com/doi/10.1089/...
www.liebertpub.com
January 26, 2025 at 11:03 PM
I'm not familiar with any similar nutritional immune response involving zinc though.
However, limiting zinc availability to sensitize bacteria to antibiotics isn't a novel idea. Here's 2020 paper about using chelators to sensitize bacteria to carbapenems. www.liebertpub.com/doi/10.1089/...
However, limiting zinc availability to sensitize bacteria to antibiotics isn't a novel idea. Here's 2020 paper about using chelators to sensitize bacteria to carbapenems. www.liebertpub.com/doi/10.1089/...