Jan Trnka
@jantrnka.bsky.social
Scientist, teacher, wanderer, musician. Cancer metabolism, mitochondria, Bayesian #rstats at Charles University.
ORCID https://orcid.org/0000-0002-1786-7562
Lectures https://www.youtube.com/@jantrnka227
Music https://severninastupiste.bandcamp.com
ORCID https://orcid.org/0000-0002-1786-7562
Lectures https://www.youtube.com/@jantrnka227
Music https://severninastupiste.bandcamp.com
Not that surprising but still fascinating.
Our cells differ in their genetic information, some quite substantially, e.g. missing the Y chromosome in a male-presenting individual.
Our cells differ in their genetic information, some quite substantially, e.g. missing the Y chromosome in a male-presenting individual.
We are all mosaics: vast genetic diversity found between cells in a single person
Technical advances allow researchers to trace the genetic changes that occur over time.
www.nature.com
November 26, 2025 at 8:06 PM
Not that surprising but still fascinating.
Our cells differ in their genetic information, some quite substantially, e.g. missing the Y chromosome in a male-presenting individual.
Our cells differ in their genetic information, some quite substantially, e.g. missing the Y chromosome in a male-presenting individual.
Reposted by Jan Trnka
Ilya!!!!
www.dwarkesh.com/p/ilya-sutsk...
www.dwarkesh.com/p/ilya-sutsk...
Ilya Sutskever – We're moving from the age of scaling to the age of research
“These models somehow just generalize dramatically worse than people. It's a very fundamental thing.”
www.dwarkesh.com
November 25, 2025 at 6:07 PM
Ilya!!!!
www.dwarkesh.com/p/ilya-sutsk...
www.dwarkesh.com/p/ilya-sutsk...
Reposted by Jan Trnka
November 25, 2025 at 4:55 PM
Reposted by Jan Trnka
Today, our city mourns the loss of Mother Viola Fletcher - a survivor of one of the darkest chapters in our city's history. Mother Fletcher endured more than anyone should, yet she spent her life lighting a path forward with purpose," Nichols said on social media.
Viola Ford Fletcher, oldest survivor of Tulsa Race Massacre, dies at age 111
Viola Ford Fletcher, the oldest survivor of the 1921 Tulsa Race Massacre, has died at the age of 111, Tulsa Mayor Monroe Nichols announced Monday.
www.cbsnews.com
November 24, 2025 at 11:57 PM
Today, our city mourns the loss of Mother Viola Fletcher - a survivor of one of the darkest chapters in our city's history. Mother Fletcher endured more than anyone should, yet she spent her life lighting a path forward with purpose," Nichols said on social media.
In mice.
Time to think about the flu
@shaonsengupta.bsky.social show disruptions in daily light cycles after infection worsen influenza outcomes, but timed meals can restore protection—highlighting how circadian rhythms shape immune defense.
www.jci.org/articles/vie...
@shaonsengupta.bsky.social show disruptions in daily light cycles after infection worsen influenza outcomes, but timed meals can restore protection—highlighting how circadian rhythms shape immune defense.
www.jci.org/articles/vie...
November 24, 2025 at 5:19 PM
In mice.
Reposted by Jan Trnka
Gentle reminder that a correlation coefficient isn’t a particularly great way to quantify the effect of a dichotomous treatment. See also
www.the100.ci/2025/07/28/w...
www.the100.ci/2025/07/28/w...
November 24, 2025 at 7:23 AM
Gentle reminder that a correlation coefficient isn’t a particularly great way to quantify the effect of a dichotomous treatment. See also
www.the100.ci/2025/07/28/w...
www.the100.ci/2025/07/28/w...
Máme venku nové album, tož poslouchejte!
Nové písně, by Severní nástupiště
7 track album
severninastupiste.bandcamp.com
November 24, 2025 at 3:48 PM
Máme venku nové album, tož poslouchejte!
Přijde mi smutno-vtipné, že Zdeněk Hřib, který dělá fakt to úplně nejmenší minimum proti převálcování Prahy auty, dostává takovou bídu.
Pražské dopravní peklo. Kolaps, říká za opozici Ondřej Prokop z ANO – a viní náměstka pro dopravu Zdeňka Hřiba z Pirátů. Ten oponuje, že se na opravy dlouho kašlalo a žene motoristy do MHD.
🎧 Hostem podcastu #vinohradska12 je Aleš Rod z Centra ekonomických a tržních analýz a Národní ekonomické […]
🎧 Hostem podcastu #vinohradska12 je Aleš Rod z Centra ekonomických a tržních analýz a Národní ekonomické […]
Original post on mastodon.rozhlas.cz
mastodon.rozhlas.cz
November 24, 2025 at 8:15 AM
Přijde mi smutno-vtipné, že Zdeněk Hřib, který dělá fakt to úplně nejmenší minimum proti převálcování Prahy auty, dostává takovou bídu.
Reposted by Jan Trnka
“Are we the baddies?”
November 24, 2025 at 3:24 AM
“Are we the baddies?”
Chodci, na***te si!
November 22, 2025 at 8:24 PM
Chodci, na***te si!
Reposted by Jan Trnka
Dnes to mám vskutku se vším všudy. 😀
A po dvaceti minutách? Dobrý den a na shledanou. Příslušníci z vedlejší stanice se ani neobtěžovali přijít podívat, proč tam zvoním jak na lesy, a MP zcela nevidno. No co, jen lidem nejela tramvaj, že.
A po dvaceti minutách? Dobrý den a na shledanou. Příslušníci z vedlejší stanice se ani neobtěžovali přijít podívat, proč tam zvoním jak na lesy, a MP zcela nevidno. No co, jen lidem nejela tramvaj, že.
November 22, 2025 at 4:20 PM
Dnes to mám vskutku se vším všudy. 😀
A po dvaceti minutách? Dobrý den a na shledanou. Příslušníci z vedlejší stanice se ani neobtěžovali přijít podívat, proč tam zvoním jak na lesy, a MP zcela nevidno. No co, jen lidem nejela tramvaj, že.
A po dvaceti minutách? Dobrý den a na shledanou. Příslušníci z vedlejší stanice se ani neobtěžovali přijít podívat, proč tam zvoním jak na lesy, a MP zcela nevidno. No co, jen lidem nejela tramvaj, že.
Reposted by Jan Trnka
Getting journal rejections like
November 21, 2025 at 5:50 PM
Getting journal rejections like
Reposted by Jan Trnka
So I’m very committed to critiquing elected officials, and cringe at cults of personality and all that leftist jazz— but is Zohran, like, a sorcerer?
November 21, 2025 at 11:36 PM
So I’m very committed to critiquing elected officials, and cringe at cults of personality and all that leftist jazz— but is Zohran, like, a sorcerer?
"But I’ve been watching technology long enough to know that when something requires this much money, this much hype, and this many contradictions to explain itself, it’s worth asking what else might be going on."
(I suspect it is all of the things in the article.)
(I suspect it is all of the things in the article.)
What AI is Really For - Christopher Butler
After three years of immersion in AI, I have come to a relatively simple conclusion: it’s a useful technology that is very likely overhyped to the
www.chrbutler.com
November 22, 2025 at 7:45 AM
"But I’ve been watching technology long enough to know that when something requires this much money, this much hype, and this many contradictions to explain itself, it’s worth asking what else might be going on."
(I suspect it is all of the things in the article.)
(I suspect it is all of the things in the article.)
Sure. And the fight against multiresistant bacterial infections has nothing against the poor bacteria - just the unpleasant deaths they cause! 🤦🏽
European Commission President Ursula von der Leyen said today that the fight against climate change was not against the fuels that cause it — only the pollution they emit.
Von der Leyen says EU is not fighting fossil fuels, only emissions
The comment could undermine European countries’ push at COP30 to move away from coal, oil and gas.
www.politico.eu
November 21, 2025 at 2:26 PM
Sure. And the fight against multiresistant bacterial infections has nothing against the poor bacteria - just the unpleasant deaths they cause! 🤦🏽
Reposted by Jan Trnka
Jedna zajímavost z Prahy: Kačerov a Spořilov jsou od vzdálené cca 10 minut chůze. Teda byly by, kdyby cesta nekončila u OMV a Magistrála + Spojka nevytvářely neprostupnou překážku.
Podobné nespojitosti mají obrovský dopad nejen "urbanistický", ale také ekonomický. V Praze jsou všude.
Podobné nespojitosti mají obrovský dopad nejen "urbanistický", ale také ekonomický. V Praze jsou všude.
November 21, 2025 at 1:28 PM
Jedna zajímavost z Prahy: Kačerov a Spořilov jsou od vzdálené cca 10 minut chůze. Teda byly by, kdyby cesta nekončila u OMV a Magistrála + Spojka nevytvářely neprostupnou překážku.
Podobné nespojitosti mají obrovský dopad nejen "urbanistický", ale také ekonomický. V Praze jsou všude.
Podobné nespojitosti mají obrovský dopad nejen "urbanistický", ale také ekonomický. V Praze jsou všude.
Reposted by Jan Trnka
"Greeks living in Afghanistan were Buddhist 500 years before China and a thousand years before Southeast Asia" is one of those things that sounds made up but is in fact true
November 20, 2025 at 3:25 PM
"Greeks living in Afghanistan were Buddhist 500 years before China and a thousand years before Southeast Asia" is one of those things that sounds made up but is in fact true
Reposted by Jan Trnka
👍
Pavel Himl: Mají-li si univerzity zachovat smysl, nesmí záviset na politické moci
Ačkoli se nejčastěji mluví o podfinancovanosti vysokých škol, nesmíme přehlížet ani nebezpečí zásahů do samosprávy univerzit, které by oslabily jejich odolnost vůči politickým tlakům, ekonomickým zájm...
denikreferendum.cz
November 20, 2025 at 11:14 PM
👍
Reposted by Jan Trnka
November 21, 2025 at 8:14 AM
Reposted by Jan Trnka
Zítra nám z tiskárny přivezou novinku - "Jiné teď" od Janise Varufakise.
Knihu si můžete už objednat už teď u nás na webu. 👇
Knihu si můžete už objednat už teď u nás na webu. 👇
Jiné teď / Janis Varufakis - Nakladatelství Neklid
Jiné teď / Janis Varufakis. Varufakisovo politické sci-fi je pozitivní odpovědí na otázku, jak by měla fungovat společnost, které překoná kapitalismus a rozhodne se pro sociálně spravedlivou alternati...
www.neklid.org
November 20, 2025 at 7:11 PM
Zítra nám z tiskárny přivezou novinku - "Jiné teď" od Janise Varufakise.
Knihu si můžete už objednat už teď u nás na webu. 👇
Knihu si můžete už objednat už teď u nás na webu. 👇
Reposted by Jan Trnka
1908 chart arrived from Germany showing mineral water analysis in Bohemia, by Ferdinand Vogel, military spa doctor in Bílina.
(@letterformarchive.org check-out these pretty letters)
(@letterformarchive.org check-out these pretty letters)
November 20, 2025 at 6:18 AM
1908 chart arrived from Germany showing mineral water analysis in Bohemia, by Ferdinand Vogel, military spa doctor in Bílina.
(@letterformarchive.org check-out these pretty letters)
(@letterformarchive.org check-out these pretty letters)
Reposted by Jan Trnka
Given SpaceX's record, Grokipedia is most likely to be distributed in a half mile radius around the launch site.
November 19, 2025 at 7:03 PM
Given SpaceX's record, Grokipedia is most likely to be distributed in a half mile radius around the launch site.
Reposted by Jan Trnka
When I arrive at the party
November 19, 2025 at 5:53 AM
When I arrive at the party
Reposted by Jan Trnka
new paper by Sean Westwood:
With current technology, it is impossible to tell whether survey respondents are real or bots. Among other things, makes it easy for bad actors to manipulate outcomes. No good news here for the future of online-based survey research
With current technology, it is impossible to tell whether survey respondents are real or bots. Among other things, makes it easy for bad actors to manipulate outcomes. No good news here for the future of online-based survey research
November 18, 2025 at 7:16 PM
new paper by Sean Westwood:
With current technology, it is impossible to tell whether survey respondents are real or bots. Among other things, makes it easy for bad actors to manipulate outcomes. No good news here for the future of online-based survey research
With current technology, it is impossible to tell whether survey respondents are real or bots. Among other things, makes it easy for bad actors to manipulate outcomes. No good news here for the future of online-based survey research