#fattyacid
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mol-biomed.bsky.social
#Review
Long-chain acyl-CoA synthetases: biological functions, diseases and therapeutic targets doi.org/10.1186/s435...

#Cancer #ACSLs #FattyAcid #metabolism #Ferroptosis #MetabolicDisease #Cardiovascular #Cerebrovascular
Long-chain acyl-CoA synthetases: biological functions, diseases and therapeutic targets - Molecular Biomedicine
The long-chain acyl-CoA synthetase (ACSL) family comprises key enzymes that are integral to the fatty acid metabolic pathway and play crucial roles in governing fatty acid (FA) metabolism and lipid ho...
doi.org
December 5, 2025 at 2:45 AM
thentix.bsky.social
✨Your hair deserves the best—naturally. Thentix Moroccan Hair Oil with Argan Oil hydrates, tames frizz, adds shine, protects, soothes scalp & helps prevent breakage. 💛🌬️✨

#hairoil #arganoil #fattyacids #fattyacid #protectyourhair #besthair
November 7, 2025 at 2:06 PM
joensuulab.bsky.social
👇🏻👇🏻👇🏻👇🏻👇🏻👇🏻👇🏻👇🏻👇🏻👇🏻👇🏻👇🏻 #neuron #energy #metabolism #fattyacid #raredisease #HSP #mitochondria #betaoxidation #brain #health #neurodegeneration Read more here: rdcu.be/eIQA0 🧠 🔬
October 3, 2025 at 2:41 AM
safaker.bsky.social
It was amazing to be part of this ground-breaking work: “DDHD2 provides a flux of saturated fatty acids for neuronal energy and function”, Nature Metabolism @nature.com

Congratulations to Saber… Joensuu et al and all authors! 🎉

#energy #neuron #mitochondria #fats #fattyacid

(1/2)
September 30, 2025 at 11:53 AM
getnews-me.bsky.social
Injecting aged mice with a targeted polyunsaturated fatty acid quickly restored retinal function to levels seen with gene enhancement; the study was published in Science Translational Medicine. https://getnews.me/fat-supplement-restores-vision-in-aging-mice-study-shows/ #vision #aging #fattyacid
Fat Supplement Restores Vision in Aging Mice, Study Shows
September 27, 2025 at 12:51 PM
genesndiseases.bsky.social
This study explores the energy status & regulation of #Glucose & #FattyAcid utilization in cTnI193His-M mice in the early stages of #DiastolicDysfunction, providing insights for future #therapeutic strategies for #HeartFailure. #medsky
#OpenAccess:
www.sciencedirect.com/science/arti...
September 21, 2025 at 1:18 PM
ajstein.bsky.social
Meat & #dairy substitutes gain popularity. Using #plantbased substitutes—with reduced consumption of red & processed #meat, increased #fiber & improved #fattyacid intake—would be the most effective in reducing premature deaths from #cancer & cardiometabolic diseases… (1/2) doi.org/10.1016/j.aj...
Redirecting
doi.org
July 29, 2025 at 2:43 PM
genesndiseases.bsky.social
This review discusses #fattyacid-associated metabolic changes in #cancers and tumor–non-tumor cell interactions within the #TumorMicroenvironment, focusing on new targets for combination therapy with #MetabolicReprogramming and #immunotherapy. #medsky
#OpenAccess:
www.sciencedirect.com
July 19, 2025 at 12:30 AM
sueray328.bsky.social
Essential fatty acids, found in #fats & #oils, are essential nutrients. However, some fats are low in these nutrients, such as #oliveoil, which requires 2,000 #calories to meet the daily #omega3 #fattyacid intake, compared to #soybean oil's 200 calories. #healthyaging #aging
June 18, 2025 at 5:44 PM
microbesinfo.bsky.social
Host fatty #acids enhance #dengue #virus #infectivity ...

| #flavivirus | #infections | #fattyacid | #mosquito | #elongase | #desaturase | Via @asbmb.bsky.social‬
Host fatty acids enhance dengue virus infectivity
Researchers in Germany found that viral replication depends on host enzymes that synthesize lipids, revealing potential metabolic targets for antiviral intervention. Read more about this recent…
www.asbmb.org
June 15, 2025 at 1:02 PM
thefsbi.bsky.social
#Eels can complete their growing phase in either marine or freshwater environments. Their essential #fattyacid composition is likely defined by food intake and environment but correlations between FA biosynthesis genes suggested that genetics may also play a role: doi.org/10.1111/jfb.16052 #JFB
doi.org
May 22, 2025 at 3:20 PM
physrep.bsky.social
This new Short report studies trans-right #ventricle #metabolite gradients in individuals with #obesity and identifies representation of molecular pathways including #fattyacid oxidation, #bileacids and #acylcarnitines.

doi.org/10.14814/phy...
May 16, 2025 at 9:02 AM
plosbiology.org
#Chlamydia cause millions of infections annually, but their obligate intracellular lifestyle makes treatment difficult. This study develops a platform that identified >60 new #antichlamydial compounds, including one that inhibits bacterial #FattyAcid synthesis @plosbiology.org 🧪 plos.io/4jycCuT
Top left: Chemical structures of the five most potent compounds. Bottom left: Determining the stage in Chlamydia development targeted by our best antichlamydials. Illustration of the chlamydial developmental cycle. Effect of top compounds on EB formation in HeLa cells infected with CTL2-GFP; growth inhibition after addition of top compounds (10 µM) at different points in the developmental cycle, tested in HeLa cells infected with CTL2-GFP, as measured at 48 hpi by bulk GFP fluorescence. Right: Fluorescent microscopy images corresponding to selected time points of HeLa cells infected with CTL2-GFP and treated with different concentrations of c1e, c4e or azithromycin.
May 1, 2025 at 7:53 AM
plosbiology.org
#Chlamydia cause millions of infections annually, but their obligate intracellular lifestyle makes treatment difficult. This study develops a platform that identified >60 new #antichlamydial compounds, including one that inhibits bacterial #FattyAcid synthesis @plosbiology.org 🧪 plos.io/4jycCuT
Top left: Chemical structures of the five most potent compounds. Bottom left: Determining the stage in Chlamydia development targeted by our best antichlamydials. Illustration of the chlamydial developmental cycle. Effect of top compounds on EB formation in HeLa cells infected with CTL2-GFP; growth inhibition after addition of top compounds (10 µM) at different points in the developmental cycle, tested in HeLa cells infected with CTL2-GFP, as measured at 48 hpi by bulk GFP fluorescence. Right: Fluorescent microscopy images corresponding to selected time points of HeLa cells infected with CTL2-GFP and treated with different concentrations of c1e, c4e or azithromycin.
April 30, 2025 at 4:54 PM
plosbiology.org
#Chlamydia cause millions of infections annually, but their obligate intracellular lifestyle makes treatment difficult. This study develops a platform that identified >60 new #antichlamydial compounds, including one that inhibits bacterial #FattyAcid synthesis @plosbiology.org 🧪 plos.io/4jycCuT
Top left: Chemical structures of the five most potent compounds. Bottom left: Determining the stage in Chlamydia development targeted by our best antichlamydials. Illustration of the chlamydial developmental cycle. Effect of top compounds on EB formation in HeLa cells infected with CTL2-GFP; growth inhibition after addition of top compounds (10 µM) at different points in the developmental cycle, tested in HeLa cells infected with CTL2-GFP, as measured at 48 hpi by bulk GFP fluorescence. Right: Fluorescent microscopy images corresponding to selected time points of HeLa cells infected with CTL2-GFP and treated with different concentrations of c1e, c4e or azithromycin.
April 30, 2025 at 11:46 AM
physrep.bsky.social
This research on #plasma #metabolomes before and after #exercise in weightlifters, endurance runners or sedentary individuals identifies distinct effects on certain metabolites of #fattyacid #metabolism and oxidative defence.
https://buff.ly/4b1xGGs
#Biomarkers #OxidativeStress
buff.ly
February 14, 2025 at 11:07 AM
rgmm.bsky.social
#FattyAcid&sephire #FinalFantasyX-2 #UnderANewMoon #OverClockedReMix #Feb17 #RGMM #Musicsky
OC ReMix #1357: Final Fantasy X-2 'Under a New Moon' [Kuon] by Fatty Acid & sephfire
YouTube video by OverClocked ReMix: Video Game Music Community
youtu.be
February 7, 2025 at 5:49 PM
kristinagrozic.bsky.social
Effect of Mussel Meal Feed Supplement on Growth, Health Status, Proximate Composition and Fatty Acid Profile of Gilthead Seabream (Sparus aurata)
www.mdpi.com/2410-3888/9/...

#fish #aquaculture #seabream #mussel #fishfeed #Fattyacid #sustainability #research
December 28, 2024 at 12:16 PM
tkozawa.bsky.social
Great work by Liu et al. (2024) on how #PlantTOR kinase positively regulates plant #FattyAcid and lipid synthesis in #Nicotiana benthamiana leaves 🍃, #Arabidopsis seedlings 🌱 and #Brassica napus suspension cells.
PS. Relatively short periods were used for the assays.
academic.oup.com/plphys/advan...
Figure 7. Target of Rapamycin (TOR) kinase is a positive regulator of plant fatty acid and lipid synthesis. Plant TOR is activated by light and sugars. Once activated, TOR positively regulates fatty acid (FA) and lipid synthesis by upregulating genes involved in de novo fatty acid synthesis and downregulating genes associated with lipid turnover. Additionally, TOR promotes the biosynthesis of proteins, cell walls, DNA, RNA, and the other essential cellular components. TOR complex shown in the figure is comprising of LST8-1 (Lethal with SEC13 protein 8-1, in green), TOR (in purple) and RAPTOR1B (Regulatory-associated protein of TOR 1B, in yellow) and its 3D structure model is predicated by AlphaFold 3. Figure 1. Transient expression of TOR in Nicotiana benthamiana (N. benth) leaves increases the levels of total fatty acids (TFAs). A) Representative fluorescence confocal image of N. benth leaf samples taken 4 days after agroinfiltration with TOR-GFP. Bar = 50 µm. B) Immunoblotting with anti-GFP antibody shows TOR-GFP is detected in protein samples extracted from N. benth leaves 4 days after infiltration with agrobacterium containing plasmid TOR/pCHF3-hGFP (TOR-GFP), but not pCHF3-hGFP (Empty vector, EV). Ponceau S staining of PVDF membrane after protein transfer is shown as a protein loading control. M, protein markers. Multiple lanes for the same construct represent biological replicates. C) Transient expression of TOR for 4 days after agroinfiltration significantly elevates total fatty acids content in N. benth leaves after. Bar values represent mean ± SD (n = 6), with each data point represented by a dot. Asterisks denote a statistically difference from the EV (Student's t-test, **, P < 0.01). Figure 5. Suppression of TOR activity by Torin 2 in a Brassica napus suspension cell culture results in significant reduction in the accumulation of both total fatty acid (TFA) and triacylglycerol (TAG). A) TFA content in Brassica napus microspore-derived suspension cells cultured in medium supplemented without (−) or with (+) 1 μM Torin 2 for the indicated time periods. B) TAG content in the Brassica napus suspension cells in (A). In this figure, bar values represent mean ± SD (n = 4), with each data point represented by a dot. Asterisks denote statistically significant differences from the non-Torin 2 treatment controls (Student’s t-test, *, P < 0.05; ***, P < 0.001).
December 4, 2024 at 1:24 AM
elivera.bsky.social
eliveragroup.com/products/pro...
#PROPIONICACID 500 mg #vegan capsules
#sodiumpropionate for the natural formation of the short-chain #fattyacid propionic acid in the #intestine. One #vegancapsule contains 500 mg of pure sodium propionate
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eliveragroup.com
November 17, 2024 at 7:10 AM
disabled-world.com
Umbilical Cord Blood Fatty Acids Linked to #AutismSpectrumDisorder

Researchers unveil the link between #cordblood #fattyacid metabolites and #ASD symptoms in children.

www.disabled-world.com/health/neuro...
Umbilical Cord Blood Fatty Acids Linked to Autism Spectrum Disorder - #DisabledWorld
Researchers unveil the link between cord blood fatty acid metabolites and autism spectrum disorder (ASD) symptoms in children.
www.disabled-world.com
July 30, 2024 at 7:25 PM
haoyin.bsky.social
My continued biomedical education

#Macrophage #Mitochondria #Atherosclerosis

OxLDL-CD36-> mitoROS->NF-κB
⏫OxPhos-to-Glycosis
⏫#FattyAcid trafficking to mito, but ⏬#FattyAcidOxidation

OxLDL fragments mito

#CircRes 2019
www.ahajournals.org/doi/10.1161/...
June 5, 2024 at 11:30 AM
conservbytes.bsky.social
Full paper out now: #FattyAcid profiles of more than 470 marine species from the Southern Hemisphere http://doi.org/10.1002/ecy.3888
November 20, 2024 at 5:03 AM
kristebellaaa.bsky.social
Can I substitute halloween candy for snickers ice cream and call it a day? #fattyacid #thisishalloween
December 1, 2024 at 3:23 PM
kristebellaaa.bsky.social
I just made/ate a stir fry that was literally dripping with oil. My heart hurts. #fattyacid #ineedtolearntouselessoil
December 1, 2024 at 4:39 PM