A new reporter mouse for visualising Hedgehog/GLI signalling activity
This Research Highlight showcases the work from Hannah Schrader Dear, Nicole Franks, Benjamin Allen and colleagues:
journals.biologists.com/dev/article/...
This Research Highlight showcases the work from Hannah Schrader Dear, Nicole Franks, Benjamin Allen and colleagues:
journals.biologists.com/dev/article/...
November 7, 2025 at 12:33 PM
A new reporter mouse for visualising Hedgehog/GLI signalling activity
This Research Highlight showcases the work from Hannah Schrader Dear, Nicole Franks, Benjamin Allen and colleagues:
journals.biologists.com/dev/article/...
This Research Highlight showcases the work from Hannah Schrader Dear, Nicole Franks, Benjamin Allen and colleagues:
journals.biologists.com/dev/article/...
A tragedy in three parts. It does actually bother me that otherwise ok-seeming people turn out to be such mefs. He was alright until that little strop 🙄
September 17, 2025 at 7:23 PM
A tragedy in three parts. It does actually bother me that otherwise ok-seeming people turn out to be such mefs. He was alright until that little strop 🙄
Fucking weirdo mefs by me having a full firework display on... October 26th?!
All the dogs round here are facing a tough fortnight ahead if this is the way it's going.
I'd like to launch these scrotes into space.
All the dogs round here are facing a tough fortnight ahead if this is the way it's going.
I'd like to launch these scrotes into space.
October 26, 2024 at 5:57 PM
Fucking weirdo mefs by me having a full firework display on... October 26th?!
All the dogs round here are facing a tough fortnight ahead if this is the way it's going.
I'd like to launch these scrotes into space.
All the dogs round here are facing a tough fortnight ahead if this is the way it's going.
I'd like to launch these scrotes into space.
2/
However, culturing naive hPSCs typically relies on mouse embryonic fibroblasts (MEFs) as a feeder layer. MEFs are variable, resource-intensive, and can confound experimental results. 🐭
How can we improve this system? Let’s explore! 👇
However, culturing naive hPSCs typically relies on mouse embryonic fibroblasts (MEFs) as a feeder layer. MEFs are variable, resource-intensive, and can confound experimental results. 🐭
How can we improve this system? Let’s explore! 👇
January 21, 2025 at 10:44 AM
2/
However, culturing naive hPSCs typically relies on mouse embryonic fibroblasts (MEFs) as a feeder layer. MEFs are variable, resource-intensive, and can confound experimental results. 🐭
How can we improve this system? Let’s explore! 👇
However, culturing naive hPSCs typically relies on mouse embryonic fibroblasts (MEFs) as a feeder layer. MEFs are variable, resource-intensive, and can confound experimental results. 🐭
How can we improve this system? Let’s explore! 👇
📢 [AI摘要] 奥克兰机场每年处理大量遗失物品，包括婴儿车、吉他等。去年，约9000公斤未认领物品捐赠给当地慈善机构MEFS，帮助有需要的人，减少机场废弃物。MEFS将物品分类整理，免费提供给有需要的家庭，支持社区。
The second life of Auckland Airport's lost property
www.rnz.co.nz
March 3, 2025 at 5:46 PM
#DBfeature #cilia
Moderate levels of folic acid benefit outcomes for cilia based neural tube defects
David Engelhardt, Juliette Petersen, Cara Martyr, Hannah Kuhn-Gale, Lee Niswander
tiom33.short.gy/DB520,62-75
Moderate levels of folic acid benefit outcomes for cilia based neural tube defects
David Engelhardt, Juliette Petersen, Cara Martyr, Hannah Kuhn-Gale, Lee Niswander
tiom33.short.gy/DB520,62-75
September 1, 2025 at 10:18 AM
#DBfeature #cilia
Moderate levels of folic acid benefit outcomes for cilia based neural tube defects
David Engelhardt, Juliette Petersen, Cara Martyr, Hannah Kuhn-Gale, Lee Niswander
tiom33.short.gy/DB520,62-75
Moderate levels of folic acid benefit outcomes for cilia based neural tube defects
David Engelhardt, Juliette Petersen, Cara Martyr, Hannah Kuhn-Gale, Lee Niswander
tiom33.short.gy/DB520,62-75
My workday requires levity. Therefore, I give you... DAVID CARUSO AND HIS SUNGLASSES OF JUSTICE! http://www.youtube.com/watch?v=FkElgo-mEFs
March 26, 2025 at 7:24 AM
My workday requires levity. Therefore, I give you... DAVID CARUSO AND HIS SUNGLASSES OF JUSTICE! http://www.youtube.com/watch?v=FkElgo-mEFs
some spooky westerns, from when we were given some testers from new vendors. AB's that we use in the lab are on the left.
This is why I usually stick to CST (90% of our ab's), Thermo, BD, Active Motif and handful of others
This is why I usually stick to CST (90% of our ab's), Thermo, BD, Active Motif and handful of others
December 26, 2024 at 2:40 PM
some spooky westerns, from when we were given some testers from new vendors. AB's that we use in the lab are on the left.
This is why I usually stick to CST (90% of our ab's), Thermo, BD, Active Motif and handful of others
This is why I usually stick to CST (90% of our ab's), Thermo, BD, Active Motif and handful of others
Migraines are the worst. Do you have mefs for them? I used to have fairly extreme migraines, but my mefs make all the difference.
And for some temporary releave; try a cold soda *with* sparkles. It doesn't solve, but it does sooth.
Hang in there! x
And for some temporary releave; try a cold soda *with* sparkles. It doesn't solve, but it does sooth.
Hang in there! x
February 23, 2025 at 7:46 PM
Migraines are the worst. Do you have mefs for them? I used to have fairly extreme migraines, but my mefs make all the difference.
And for some temporary releave; try a cold soda *with* sparkles. It doesn't solve, but it does sooth.
Hang in there! x
And for some temporary releave; try a cold soda *with* sparkles. It doesn't solve, but it does sooth.
Hang in there! x
To test this we looked at how VASP responds to our laser ablation in WT and zyxin KO MEFs. We only saw a change in VASP intensity at the FA when zyxin was present! We also measured retrograde flow of actin at FAs and found that it was slower in the zyxin KO cells!
July 21, 2025 at 5:33 PM
To test this we looked at how VASP responds to our laser ablation in WT and zyxin KO MEFs. We only saw a change in VASP intensity at the FA when zyxin was present! We also measured retrograde flow of actin at FAs and found that it was slower in the zyxin KO cells!
The amount of pokemon stuff was insane. I know I already said it but thank you Mefs :( 💜
October 27, 2025 at 11:37 PM
The amount of pokemon stuff was insane. I know I already said it but thank you Mefs :( 💜
NIAGRA N=1063, mEFS NR vs 46.1 w/ CT alone; HR=0.68 P<0.0001. mOS, NR in both arms HR=0.75, P=0.0106
March 29, 2025 at 1:12 PM
NIAGRA N=1063, mEFS NR vs 46.1 w/ CT alone; HR=0.68 P<0.0001. mOS, NR in both arms HR=0.75, P=0.0106
Cycling Weather
www.youtube.com/watch?v=MEFS...
www.youtube.com/watch?v=MEFS...
Happy Cycling
Provided to YouTube by IIP-DDSHappy Cycling · Boards of CanadaMusic Has The Right To Children℗ Warp RecordsReleased on: 1998-04-20Auto-generated by YouTube.
www.youtube.com
July 9, 2024 at 5:30 PM
Cycling Weather
www.youtube.com/watch?v=MEFS...
www.youtube.com/watch?v=MEFS...
But what if he bank roles Meloni, Le Pen, Orban etc? The whole of Europe is in danger of navel gazing and allowing their own bad mefs to run amok. I believe closer ties with EU are key, but the problem I think we all have, is in assuming it's the EU of Merkel et al. Not this current lot.
December 6, 2024 at 10:21 AM
But what if he bank roles Meloni, Le Pen, Orban etc? The whole of Europe is in danger of navel gazing and allowing their own bad mefs to run amok. I believe closer ties with EU are key, but the problem I think we all have, is in assuming it's the EU of Merkel et al. Not this current lot.
ER-lysosome contact sites (green) in MEFs on the background of an ER stain (grey, GFP-VAPA)
December 4, 2024 at 6:29 PM
ER-lysosome contact sites (green) in MEFs on the background of an ER stain (grey, GFP-VAPA)
I’m fighting my sleep mefs
July 15, 2025 at 3:04 AM
I’m fighting my sleep mefs
god i was off my ADHD mefs for a few as a lil break and while it was nice to not have my Productivity Switch forcibly welded to the 'on' position GOD am I glad to be back on them I feel so much more capable of basic selfcare
August 5, 2025 at 1:33 PM
god i was off my ADHD mefs for a few as a lil break and while it was nice to not have my Productivity Switch forcibly welded to the 'on' position GOD am I glad to be back on them I feel so much more capable of basic selfcare
okay will stifj to mefs
July 1, 2025 at 1:11 PM
okay will stifj to mefs
New pooled library alert! These lentiviral barcoding libraries from the Morris lab can be used to combinatorially index cells for single-cell analysis of clonal dynamics.
www.addgene.org/pooled-libra...
www.addgene.org/pooled-libra...
January 17, 2024 at 7:57 PM
New pooled library alert! These lentiviral barcoding libraries from the Morris lab can be used to combinatorially index cells for single-cell analysis of clonal dynamics.
www.addgene.org/pooled-libra...
www.addgene.org/pooled-libra...
This is a confocal micrograph of two mouse embryonic fibroblast cells. The connections between the cells are NOT cytonemes - but they still look cool! Image by @erichall.bsky.social #DevBio #SciArt 🧪
🔬
🔬
August 28, 2024 at 2:33 PM
This is a confocal micrograph of two mouse embryonic fibroblast cells. The connections between the cells are NOT cytonemes - but they still look cool! Image by @erichall.bsky.social #DevBio #SciArt 🧪
🔬
🔬
DUDE THE SHOPPERS APP UNDOWNLOADED ON MY PHONE NO WONDER I DIDNT KNOW I NEEDED TO REFILL MY MEFS BRO
February 16, 2025 at 7:27 PM
DUDE THE SHOPPERS APP UNDOWNLOADED ON MY PHONE NO WONDER I DIDNT KNOW I NEEDED TO REFILL MY MEFS BRO
Brentford are bad wools for chanting “VAR…” at the end there.
Chinless mefs
Anyway. 7 unbeaten for the Toffees.
Up the Blues! 💙
Chinless mefs
Anyway. 7 unbeaten for the Toffees.
Up the Blues! 💙
February 26, 2025 at 9:50 PM
Brentford are bad wools for chanting “VAR…” at the end there.
Chinless mefs
Anyway. 7 unbeaten for the Toffees.
Up the Blues! 💙
Chinless mefs
Anyway. 7 unbeaten for the Toffees.
Up the Blues! 💙
#ScottishSongbook
ROUND 2 - GROUP 21
@acidmouse.bsky.social
Happy Cycling – Boards Of Canada
www.youtube.com/watch?v=MEFS...
ROUND 2 - GROUP 21
@acidmouse.bsky.social
Happy Cycling – Boards Of Canada
www.youtube.com/watch?v=MEFS...
Happy Cycling
YouTube video by Boards of Canada - Topic
www.youtube.com
January 29, 2025 at 6:04 PM
#ScottishSongbook
ROUND 2 - GROUP 21
@acidmouse.bsky.social
Happy Cycling – Boards Of Canada
www.youtube.com/watch?v=MEFS...
ROUND 2 - GROUP 21
@acidmouse.bsky.social
Happy Cycling – Boards Of Canada
www.youtube.com/watch?v=MEFS...