Adipocytes Impair Mitoxantrone Cytotoxicity Against Acute Lymphoblastic Leukemia
onlinelibrary.wiley.com/doi/epdf/10....
onlinelibrary.wiley.com/doi/epdf/10....
September 15, 2025 at 11:02 AM
Adipocytes Impair Mitoxantrone Cytotoxicity Against Acute Lymphoblastic Leukemia
onlinelibrary.wiley.com/doi/epdf/10....
onlinelibrary.wiley.com/doi/epdf/10....
Comparison of outcomes in feline intermediate- to large-cell lymphoma treated with CMOP (cyclophosphamide, mitoxantrone, vincristine and prednisolone) instead of CHOP (cyclophosphamide, doxorubicin, vincristine and prednisolone) journals.sagepub.com/doi/full/10....
June 1, 2025 at 5:20 AM
Comparison of outcomes in feline intermediate- to large-cell lymphoma treated with CMOP (cyclophosphamide, mitoxantrone, vincristine and prednisolone) instead of CHOP (cyclophosphamide, doxorubicin, vincristine and prednisolone) journals.sagepub.com/doi/full/10....
The effects are not limited to HSCs, of course; intuition is often faulty regarding the on-target vs off-target effects of agents like doxorubicin and mitoxantrone www.sciencedirect.com/science/arti...
Exploring the aging effect of the anticancer drugs doxorubicin and mitoxantrone on cardiac mitochondrial proteome using a murine model
Current cancer therapies are successfully increasing the lifespan of cancer patients. Nevertheless, cardiotoxicity is a serious chemotherapy-induced a…
www.sciencedirect.com
July 1, 2025 at 2:43 PM
The effects are not limited to HSCs, of course; intuition is often faulty regarding the on-target vs off-target effects of agents like doxorubicin and mitoxantrone www.sciencedirect.com/science/arti...
A Metal–Organic Framework Nanocarrier System for Precise Targeted Delivery and Reduced Systemic Toxicity of Mitoxantrone in Breast Cancer Therapy http://dx.doi.org/10.1021/acsami.5c14630
October 25, 2025 at 1:16 PM
A Metal–Organic Framework Nanocarrier System for Precise Targeted Delivery and Reduced Systemic Toxicity of Mitoxantrone in Breast Cancer Therapy http://dx.doi.org/10.1021/acsami.5c14630
Mitoxantrone Hydrochloride Injection (Tracer) – 5 mg
Mitoxantrone hydrochloride injection for tracing is a lymphatic tracer approved by NMPA (H20227061) for sentinel lymph node mapping during surgery. Packaged as 1 mL prefilled syringes containing 5 mg/mL solution, produced by Shanghai Chuangnuo…
Mitoxantrone hydrochloride injection for tracing is a lymphatic tracer approved by NMPA (H20227061) for sentinel lymph node mapping during surgery. Packaged as 1 mL prefilled syringes containing 5 mg/mL solution, produced by Shanghai Chuangnuo…
Mitoxantrone Hydrochloride Injection (Tracer) – 5 mg
Mitoxantrone hydrochloride injection for tracing is a lymphatic tracer approved by NMPA (H20227061) for sentinel lymph node mapping during surgery. Packaged as 1 mL prefilled syringes containing 5 mg/mL solution, produced by Shanghai Chuangnuo Pharma (barcode 86900647000237). This tracer forms nanocrystals that preferentially accumulate in lymph nodes and stain them blue—enabling clear identification without radioactivity. **Strictly for experimental use（Please consult the staff for other purposes）
arizona-mall.com
June 20, 2025 at 9:58 AM
Mitoxantrone Hydrochloride Injection (Tracer) – 5 mg
Mitoxantrone hydrochloride injection for tracing is a lymphatic tracer approved by NMPA (H20227061) for sentinel lymph node mapping during surgery. Packaged as 1 mL prefilled syringes containing 5 mg/mL solution, produced by Shanghai Chuangnuo…
Mitoxantrone hydrochloride injection for tracing is a lymphatic tracer approved by NMPA (H20227061) for sentinel lymph node mapping during surgery. Packaged as 1 mL prefilled syringes containing 5 mg/mL solution, produced by Shanghai Chuangnuo…
Presumably Methylene Blue but could be Mitoxantrone too.
September 13, 2025 at 6:10 PM
Presumably Methylene Blue but could be Mitoxantrone too.
We welcome you to read the paper: Surveying the Proteome-Wide Landscape of Mitoxantrone and Examining Drug Sensitivity in BRCA1-Deficient Ovarian Cancer Using Quantitative #Proteomics 🧬🧪🧫🥼
www.mdpi.com/2227-7382/13...
@unmc.bsky.social
#proteomes #proteoform #mitoxantrone #cancer #ribosome #DNA
www.mdpi.com/2227-7382/13...
@unmc.bsky.social
#proteomes #proteoform #mitoxantrone #cancer #ribosome #DNA
December 5, 2025 at 11:20 AM
We welcome you to read the paper: Surveying the Proteome-Wide Landscape of Mitoxantrone and Examining Drug Sensitivity in BRCA1-Deficient Ovarian Cancer Using Quantitative #Proteomics 🧬🧪🧫🥼
www.mdpi.com/2227-7382/13...
@unmc.bsky.social
#proteomes #proteoform #mitoxantrone #cancer #ribosome #DNA
www.mdpi.com/2227-7382/13...
@unmc.bsky.social
#proteomes #proteoform #mitoxantrone #cancer #ribosome #DNA
Product Description
1. Molecular Characteristics and Formulation
Mitoxantrone Hydrochloride Injection (CAS 70476-82-3) is a synthetic anthracenedione compound with potent antineoplastic activity. #highpuritychemical
arizona-mall.com/product/mito...
1. Molecular Characteristics and Formulation
Mitoxantrone Hydrochloride Injection (CAS 70476-82-3) is a synthetic anthracenedione compound with potent antineoplastic activity. #highpuritychemical
arizona-mall.com/product/mito...
Mitoxantrone Hydrochloride Injection | High purity | Factory manufactured - low price wholesale
Mitoxantrone hydrochloride injection for tracing is a lymphatic tracer approved by NMPA (H20227061) for sentinel lymph node mapping during surgery. Packaged as 1mL prefilled syringes containing 5mg/mL solution, produced by Shanghai Chuangnuo Pharma (barcode 86900647000237).
arizona-mall.com
November 18, 2025 at 6:09 PM
Product Description
1. Molecular Characteristics and Formulation
Mitoxantrone Hydrochloride Injection (CAS 70476-82-3) is a synthetic anthracenedione compound with potent antineoplastic activity. #highpuritychemical
arizona-mall.com/product/mito...
1. Molecular Characteristics and Formulation
Mitoxantrone Hydrochloride Injection (CAS 70476-82-3) is a synthetic anthracenedione compound with potent antineoplastic activity. #highpuritychemical
arizona-mall.com/product/mito...
[BioRxiv] Mitoxantrone Hydrochloride Targets APP and LRRK2 to Improve Neurodegeneration in Parkinson's Models
https://doi.org/10.1101/2025.10.06.680832
#neurodegeneration #biorxiv #Neurodegeneration #amyloid #neurotoxicity #mitochondrialdysfunction
https://doi.org/10.1101/2025.10.06.680832
#neurodegeneration #biorxiv #Neurodegeneration #amyloid #neurotoxicity #mitochondrialdysfunction
BioRxiv Article
doi.org
December 5, 2025 at 12:42 AM
[BioRxiv] Mitoxantrone Hydrochloride Targets APP and LRRK2 to Improve Neurodegeneration in Parkinson's Models
https://doi.org/10.1101/2025.10.06.680832
#neurodegeneration #biorxiv #Neurodegeneration #amyloid #neurotoxicity #mitochondrialdysfunction
https://doi.org/10.1101/2025.10.06.680832
#neurodegeneration #biorxiv #Neurodegeneration #amyloid #neurotoxicity #mitochondrialdysfunction
For patients with #AML, treatment regimens using mitoxantrone hydrochloride liposome therapy were considered effective and well-tolerated in a recent multicenter study.
https://bit.ly/3YeHJCC
#leusm
https://bit.ly/3YeHJCC
#leusm
Mitoxantrone Hydrochloride Liposome Regimens Effective, Safe in Acute Myeloid Leukemia - Oncology Nurse Advisor
A noninterventional, ambispective cohort analysis evaluated the real-world efficacy and safety of Lipo-MIT-containing regimens in the treatment of acute myeloid leukemia.
bit.ly
December 9, 2025 at 9:00 PM
For patients with #AML, treatment regimens using mitoxantrone hydrochloride liposome therapy were considered effective and well-tolerated in a recent multicenter study.
https://bit.ly/3YeHJCC
#leusm
https://bit.ly/3YeHJCC
#leusm
Mitoxantrone Hydrochloride Targets APP and LRRK2 to Improve Neurodegeneration in Parkinson's Models https://www.biorxiv.org/content/10.1101/2025.10.06.680832v1
October 7, 2025 at 11:15 PM
Mitoxantrone Hydrochloride Targets APP and LRRK2 to Improve Neurodegeneration in Parkinson's Models https://www.biorxiv.org/content/10.1101/2025.10.06.680832v1
Antitumor Effect of Curcumin, D6 Turmeric, and Hydrochloride Mitoxantrone on Canine and Human Urothelial Cancer Cells. www.mdpi.com/2076-2615/15...
www.mdpi.com
June 21, 2025 at 1:49 PM
Antitumor Effect of Curcumin, D6 Turmeric, and Hydrochloride Mitoxantrone on Canine and Human Urothelial Cancer Cells. www.mdpi.com/2076-2615/15...
Mitoxantrone inhibits and downregulates ERα through binding at the DBD-LBD interface https://www.biorxiv.org/content/10.1101/2025.01.07.631371v1
January 8, 2025 at 4:49 PM
Mitoxantrone inhibits and downregulates ERα through binding at the DBD-LBD interface https://www.biorxiv.org/content/10.1101/2025.01.07.631371v1
Amine-Anchored Nanoscale Covalent-Organic Framework for Detecting Kynurenine and Mitoxantrone from Biofluids and Environmental Water http://dx.doi.org/10.1021/acsapm.4c03014
November 28, 2024 at 2:13 PM
Amine-Anchored Nanoscale Covalent-Organic Framework for Detecting Kynurenine and Mitoxantrone from Biofluids and Environmental Water http://dx.doi.org/10.1021/acsapm.4c03014
Mitoxantrone in combination with clofarabine (MITCL) in children, adolescents and young adults with relapsed/refractory acute leukaemia: a phase I/II trial
MTD was 35 mg/m2/dose x 5 days and was safe, well-tolerated and resulted in an 85% CR rate
www.thelancet.com/journals/ecl...
#MedSky
MTD was 35 mg/m2/dose x 5 days and was safe, well-tolerated and resulted in an 85% CR rate
www.thelancet.com/journals/ecl...
#MedSky
May 2, 2025 at 11:37 AM
Mitoxantrone in combination with clofarabine (MITCL) in children, adolescents and young adults with relapsed/refractory acute leukaemia: a phase I/II trial
MTD was 35 mg/m2/dose x 5 days and was safe, well-tolerated and resulted in an 85% CR rate
www.thelancet.com/journals/ecl...
#MedSky
MTD was 35 mg/m2/dose x 5 days and was safe, well-tolerated and resulted in an 85% CR rate
www.thelancet.com/journals/ecl...
#MedSky
The chemotherapeutic mitoxantrone was encapsulated in platelet membrane-hybridized liposomes to enhance tumor delivery. HIFU significantly enhanced liposome accumulation and synergistically activated the pyroptosis pathway, leading to dramatic tumor growth inhibition.
October 6, 2025 at 12:24 AM
The chemotherapeutic mitoxantrone was encapsulated in platelet membrane-hybridized liposomes to enhance tumor delivery. HIFU significantly enhanced liposome accumulation and synergistically activated the pyroptosis pathway, leading to dramatic tumor growth inhibition.
A phase Ib/II trial combining brentuximab vedotin with cyclophosphamide, procarbazine, prednisone, etoposide and mitoxantrone (BrEPEM) for older patients with untreated classical Hodgkin lymphoma: A multicentre GELTAMO trial onlinelibrary.wiley.com/doi/10.1111/... #hvhebron #onco
A phase Ib/II trial combining brentuximab vedotin with cyclophosphamide, procarbazine, prednisone, etoposide and mitoxantrone (BrEPEM) for older patients with untreated classical Hodgkin lymphoma: A m...
Phase Ib/II multicentre trial for ≥60-year-old, untreated classical Hodgkin lymphoma (cHL) patients with brentuximab vedotin, cyclophosphamide, procarbazine and prednisone, mitoxantrone and etoposide....
onlinelibrary.wiley.com
August 8, 2025 at 9:12 AM
A phase Ib/II trial combining brentuximab vedotin with cyclophosphamide, procarbazine, prednisone, etoposide and mitoxantrone (BrEPEM) for older patients with untreated classical Hodgkin lymphoma: A multicentre GELTAMO trial onlinelibrary.wiley.com/doi/10.1111/... #hvhebron #onco
Mitoxantrone Hydrochloride Targets APP and LRRK2 to Improve Neurodegeneration in Parkinson's Models https://www.biorxiv.org/content/10.1101/2025.10.06.680832v1
October 7, 2025 at 11:15 PM
Mitoxantrone Hydrochloride Targets APP and LRRK2 to Improve Neurodegeneration in Parkinson's Models https://www.biorxiv.org/content/10.1101/2025.10.06.680832v1
Mitoxantrone Hydrochloride Targets APP and LRRK2 to Improve Neurodegeneration in Parkinson's Models #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.10.06.680832v1
https://www.biorxiv.org/content/10.1101/2025.10.06.680832v1
October 8, 2025 at 7:02 AM
Mitoxantrone Hydrochloride Targets APP and LRRK2 to Improve Neurodegeneration in Parkinson's Models #NeuroDegeneration 🧪🧠
https://www.biorxiv.org/content/10.1101/2025.10.06.680832v1
https://www.biorxiv.org/content/10.1101/2025.10.06.680832v1
Antitumor Effect of Curcumin, D6 Turmeric, and Hydrochloride Mitoxantrone on Canine and Human Urothelial Cancer Cells. www.mdpi.com/2076-2615/15...
June 21, 2025 at 1:05 PM
Antitumor Effect of Curcumin, D6 Turmeric, and Hydrochloride Mitoxantrone on Canine and Human Urothelial Cancer Cells. www.mdpi.com/2076-2615/15...
Dr. Andrew Kent from @cuhematology.bsky.social and @cucancercenter.bsky.social is leading a trial testing if mitoxantrone can help AML patients resistant to current treatments. This could change leukemia care. 🌟 buff.ly/IlJXWzk
#CancerResearch #MedSky
#CancerResearch #MedSky
From Bench to Bedside: CU Physician-Scientist Leading New Clinical Trial to Improve Acute Myeloid Leukemia Treatment
Expanding on previous research, Andrew Kent, MD, PhD, is leading a clinical trial to investigate whether a drug can reduce resistance to an AML treatment.
bit.ly
August 11, 2025 at 8:02 PM
Dr. Andrew Kent from @cuhematology.bsky.social and @cucancercenter.bsky.social is leading a trial testing if mitoxantrone can help AML patients resistant to current treatments. This could change leukemia care. 🌟 buff.ly/IlJXWzk
#CancerResearch #MedSky
#CancerResearch #MedSky
Mitoxantrone inhibits and downregulates ERα through binding at the DBD-LBD interface https://www.biorxiv.org/content/10.1101/2025.01.07.631371v1
January 8, 2025 at 4:49 PM
Mitoxantrone inhibits and downregulates ERα through binding at the DBD-LBD interface https://www.biorxiv.org/content/10.1101/2025.01.07.631371v1
Pascal-Raphael Blersch from Universitätsklinikum Erlangen investigate the efficacy of combining hyperthermic treatments with chemotherapeutics, such as cisplatin, docetaxel, & mitoxantrone, to develop better therapies for specific melanoma subtypes.
doi.org/10.1167/iovs.66.12.71
doi.org/10.1167/iovs.66.12.71
September 30, 2025 at 5:05 PM
Pascal-Raphael Blersch from Universitätsklinikum Erlangen investigate the efficacy of combining hyperthermic treatments with chemotherapeutics, such as cisplatin, docetaxel, & mitoxantrone, to develop better therapies for specific melanoma subtypes.
doi.org/10.1167/iovs.66.12.71
doi.org/10.1167/iovs.66.12.71