Tim Triche, Jr.🔰
@timtriche.bsky.social
5.4K followers 1.4K following 4.3K posts
Resident panhandler, http://trichelab.org/ Posts may contain trace quantities of blood🩸, chromatin 🧬, and stats 🧮 CV: https://scholar.google.com/citations?user=AOoIO74AAAAJ Views expressed are my own (but for the right price they can be yours!)
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timtriche.bsky.social
NIH funded research benefits your community even if it doesn’t (yet!) directly benefit you. Each $ invested in NIH yields significantly higher return on investment (average 254%) than the same $ invested in “defense”.

Call your reps: (202) 224-3121

www.unitedformedicalresearch.org/nih-in-your-...
NIH is a massive job creator (412041+). Non-defense spending such as NIH yields SIGNIFICANTLY higher return on investment than defense spending. In Michigan alone, $991M of NIH funding creates $2420M of economic activity, a 244% return on investment.
timtriche.bsky.social
I remember that! Brilliant choice of photo
timtriche.bsky.social
Ah, that’s too bad, I enjoy rebutting the actual reviewers’ comments and attempting to improve the paper, and I used to hope that authors I reviewed would do the same. Lately I wonder if that’s maladaptive when quantity or iMpaCt is more valued than integrity
timtriche.bsky.social
You are courageous to sign this given the proclivities of current, uh, leadership. Speaking truth to power is riskier than usual. Bravo.
timtriche.bsky.social
It used to be on UHF channels every Saturday!
timtriche.bsky.social
MongoDB: like Snapchat for data 😁
timtriche.bsky.social
I always tell students, I don’t care if you do your work in FORTRAN, R, python, JavaScript, Julia, or C. Just comment it.

Intro CS at MIT was taught in Scheme for decades, because computer science is about computers the same way astronomy is about telescopes. Stats is similar. Math >> bit fiddling
timtriche.bsky.social
So @sherlockpholmes.bsky.social pointed out recently that Claude is like having four enthusiastic new grad students banging away at a keyboard. They get a lot done but require A LOT of supervision.

We mentor by providing intuition about which questions are most likely to yield interesting answers.
timtriche.bsky.social
Same brainrot, different hat
A variety of fascistic haberdashery over the years
timtriche.bsky.social
I ditched twitter and promptly ended up with more followers and engagement here.

I’ll never buy a new Tesla and I’ll never post on that site again. I can’t support cutting aid to starving children in Myanmar.

Maybe the people who harbor moral convictions just tend to come here.
timtriche.bsky.social
Small language models are becoming more fashionable
timtriche.bsky.social
That’s cool but can you run the model on an RPN calculator? Gotta throw down 😉
timtriche.bsky.social
Good news for these guys: the United States is not such a country
timtriche.bsky.social
Sunglasses and a hat are great. There’s also a reason I, a fair skinned individual, usually keep at least a remedial beard around. (Unlike sunscreen, it does not wear off.)

A lifetime in the mountains has torched my forearms, though. That’s the part of me that really looks 50.
timtriche.bsky.social
Do take care of your back
Do take care of your knees

Don’t get too fat (see above)
Don’t get too lazy (above)

Go new places, meet people

Do something enjoyable enough that, if it doesn’t work out, you haven’t thrown away your youth for someone else’s benefit
Work really hard and one day this can be you:

(On a tombstone)

RIP
Worked Really Hard
timtriche.bsky.social
I strongly doubt that Rubio is ignorant. You don’t get to be a senator by being an ignorant fool (unless you win a lot of sportsball trophies in the SEC, and little Marco did not do that)
timtriche.bsky.social
Staring into the abyss for 8 hours a day makes for great bar stories and severe mental health issues later

I swear, we knew this 30 years ago, why is anyone pretending it isn’t so?

This is exactly what “AI” is for: attempting binary classification (with occasional human review) of OK / not OK
timtriche.bsky.social
Very well, every institute of higher learning shall have an MLK boulevard

(The “ of his time “ is understood, you see)
timtriche.bsky.social
Excellent first sentence of the introduction, doubly so for these Lysenkoist times.

Neat work!
timtriche.bsky.social
5) cheapdate
6) fruitless (ahem)
timtriche.bsky.social
Feynman had trouble following McClintock’s work. But then, plenty of biology grad students have trouble following Luria & Delbruck. Science is tough
timtriche.bsky.social
Sounds about right

Hiring MBAs to run the joint might not have been the best idea
timtriche.bsky.social
This is why I send propublica $5/month.

Comforting the afflicted and afflicting the comfortable ✊