Josh Currie
@joshcurrie.bsky.social
2.8K followers 3.5K following 320 posts
Studying principles of tissue regeneration in the axolotl and looking toward regenerative therapies. Asst. Professor at Wake Forest University. Views my own. He/him. https://www.currie-regenerationlab.com/
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joshcurrie.bsky.social
As a re-introduction to new followers, my lab at Wake Forest University studies mechanisms of regeneration in the phenomenal #axolotl with an emphasis on imaging. We think that visualizing cells and molecules in 3D/4D is vital to understanding how regeneration works!
currie-regenerationlab.com
Cells in the regenerating axolotl, labeled with a multi-colored fluorescent reporter, "Limbow" The highly regenerative Mexican axolotl (Ambystoma mexicanum)
Reposted by Josh Currie
Reposted by Josh Currie
labogden.bsky.social
Happy #FluorescenceFriday! This is a maximum intensity projection of depth shaded actin (🌈) in a section from an E9.5 🐭 neural tube (NT). 🔬 by postdoc @christinaadaly.bsky.social 👩‍🔬 🧪 Image shows the floor plate and lumen of the developing NT.

#SciArt #DevBio #DevNeuro
Rainbow shading of a confocal micrograph of a developing mouse neural tube. The protein actin is stained and colored in rainbow to indicate depth in the section.
Reposted by Josh Currie
erictopol.bsky.social
Why does the naked mole rat have the longest lifespan of any rodent, nearly 40 years?
A 30-year long mystery unraveled @ScienceMagazine today!
Its cGAS enzyme in cells has 4 missense mutations that upends its function, promoting DNA repair and suppressing inflammation
www.science.org/doi/10.1126/...
joshcurrie.bsky.social
The Nobel committee absolutely nailed the assignment to match a literature winner to 2025
cynthiapelayo.bsky.social
László 👏🏼✨

“László Krasznahorkai, who won the 2025 Nobel Prize in Literature today, is not the easiest writer to read. His sentences can go on for hundreds of pages; his plots don’t resolve, they dissolve; and his persistent mood is existential dread.”

www.theatlantic.com/books/2025/1...
Why the Latest Nobel Prize Winner Makes Perfect Sense
László Krasznahorkai is unusually experimental for a Nobel Prize winner, but in an unstable world, his selection feels perfectly timely.
www.theatlantic.com
Reposted by Josh Currie
thedailyshow.com
The following is REAL footage from Portland, 2025. Viewer discretion is advised.
Reposted by Josh Currie
atrupar.com
C-SPAN caller to Mike Johnson: "Hearing you say that 'everyone is smiling' in cities where troops have been rolled into feels dystopian and insane watching the response to it."
Reposted by Josh Currie
josephcox.bsky.social
New: Apple banned an app that simply archived videos of ICE abuses. Rather than other apps that record ICE official's real-time location, Eyes Up is to "preserve evidence until it can be used in court." Videos from TikTok etc. Every submission manually reviewed

www.404media.co/apple-banned...
Apple Banned an App That Simply Archived Videos of ICE Abuses
Eyes Up's purpose is to "preserve evidence until it can be used in court." But it has been swept up in Apple's crackdown on ICE-spotting apps.
www.404media.co
joshcurrie.bsky.social
Sad to hear about John Gurdon. In my dev bio class we, of course, talk about his foundational discoveries, but we also talk about the random serendipity that elevated a few model species into the limelight. We read this great piece by Gurdon on the history of Xenopus
The introduction of Xenopus laevis into developmental biology: of empire, pregnancy testing and ribosomal genes - PubMed
The introduction of Xenopus laevis into developmental biology: of empire, pregnancy testing and ribosomal genes
pubmed.ncbi.nlm.nih.gov
Reposted by Josh Currie
nytimes.com
Fred Ramsdell was parked at a campground in Montana on Monday when his wife suddenly started shouting. He first thought that maybe she had seen a grizzly bear. Instead, she had regained cell service and had seen a flood of text messages with the same news. “You just won the Nobel Prize!” she yelled.
Winning a Nobel Prize Interrupted His Off-the-Grid Vacation
Fred Ramsdell found out about his Nobel Prize nearly 12 hours after it was announced because he was on vacation in the Rockies.
nyti.ms
Reposted by Josh Currie
ourworldindata.org
Does the news reflect what we die from?
The image presents a comparison of the leading causes of death in the United States for 2023 and the media coverage these causes receive from three news outlets: The New York Times, The Washington Post, and Fox News. 

In the footer, it notes the data sources, indicating that the information is based on media mentions from Media Cloud (2025) and death data from the US CDC (2025) and the Global Terrorism Index, with a clarification that values are normalized to sum to 100%.
Reposted by Josh Currie
odedrechavi.bsky.social
Fwd: Fwd: “I hope this email finds you well”
joshcurrie.bsky.social
"By 'the deal,' I do not mean ....a contract by which both sides are equally bound. Instead I mean a 'deal' in the special Donald Trump sense: an agreement you and I sign that binds you to do what I want, grants me new leverage over you to demand more in the future, and does very little to bind me."
Balkinization: The Art of Replacing the Law with the Deal
A group blog on constitutional law, theory, and politics
balkin.blogspot.com
Reposted by Josh Currie
fishkin.bsky.social
The question journalists need to be asking is: WHY is the government trying this?

It’s because they want to control universities in unlawful ways that courts will not allow; it’s not working; so they’re trying to get universities to sign up “voluntarily” for unlawful levels of government control.
Reposted by Josh Currie
awfulannouncing.bsky.social
ESPN shares an interview with a UNC student going into commercial, with Clemson leading 28-3.

"TCU was... I went to that game. And that was, that was one of the saddest feelings I've had in University so far. I've failed midterms before, so that's saying something." 🏈💀 #CFB
Reposted by Josh Currie
llobrienlab.bsky.social
Sharing this excellent review now out from postdoc Sarah McLarnon! Lots of useful info on 3D imaging, quantification of imaging data, and how this has been applied to the kidney. And since it's #FluorescenceFriday, sharing a figure with our own imaging data!
www.sciencedirect.com/science/arti...
Figure from our review paper showing various fluorescence microscopy images of cells and structures of the kidney
Reposted by Josh Currie
biologists.bsky.social
Our next extraordinary biologist is Mark Peifer, recent @biologists.bsky.social Director and a prolific author, having published in @dev-journal.bsky.social, @jcellsci.bsky.social and @biologyopen.bsky.social. #100biologists
@peiferlabunc.bsky.social
The Company of Biologists 100 logo to the left and QR code to the right.
 
Portrait of Mark Peifer to the left, text to the right
 
100 extraordinary biologists

Mark Peifer

Mark Peifer is a recent Company Director and a prolific author, having published in Development, Journal of Cell Science and Biology Open. Mark is a cell and developmental biologist at the University of North Carolina, USA, investigating the epithelial tissues that form the basic architectural unit of our bodies and of those of other animals.

#100biologists #biologists100
Reposted by Josh Currie
drugmonkey.bsky.social
yep. You can't make a 'better case' that convinces tyranny of the value of science since knowledge is tyranny's kryptonite.
sciencevs.bsky.social
This moment from our latest episode with science writer @edyong209.bsky.social is 🔥

We asked Ed — how do we talk up the benefits of science in the face of government cuts? He told us that's the wrong approach. 🧪

Listen wherever, or watch on Spotify 👇

open.spotify.com/episode/7Evh...
Reposted by Josh Currie
jenvictor.bsky.social
BBC interviewer: Is there a fundamental flaw in American politics?

Me: Absolutely. The US is operating political parties software on institutional hardware that assumes parties don't exist because checks and balances will prevent tyranny. That turns out to be wrong.
www.bbc.co.uk/programmes/w...
BBC World Service - Newsday, US government shutdown
A final vote on extending government spending has failed to pass the US Senate.
www.bbc.co.uk
Reposted by Josh Currie
ryanmarino.bsky.social
This is why we fund scientists to study things like oyster slobber even if you don’t think it sounds important
leahmcelrath.bsky.social
⚠️ Chinese researchers have invented bone glue that mimics how oysters stick to surfaces underwater.

The adhesive can reportedly repair orthopedic fractures in 2-3 minutes, even in blood-rich environments, and is bioabsorbable.

interestingengineering.com/science/chin...
China's oyster-inspired 'bone glue' bonds fractures in minutes
A new oyster-inspired Bone-02 adhesive can revolutionize bone repair without metal fasteners.
interestingengineering.com
Reposted by Josh Currie
joachimgoedhart.bsky.social
Identification of optimal fluorophores for use in the Drosophila embryo by Timothy E Saunders and team: www.biorxiv.org/content/10.1...
Figure 1: Fluorophore intensity in the Drosophila blastoderm (n.c. 14). Comparison of (A) green and (B) red fluorescence intensity using the same intensity scaling in n.c. 14. The fluorescence signal did
not saturate. Shown are single imaging planes. Normalised histograms of fluorescence intensity for green (C) and red (D) fluorophores averaged across at least n=3 embryos per line. Scale bars = 20 μm
joshcurrie.bsky.social
Just a reminder if you're getting a manuscript together (like we are) to thank your core facilities!
Reposted by Josh Currie
paulwaldman.bsky.social
1. More Americans work at the Cheesecake Factory than in the entire coal industry, and that won't change. It's because of automation, not snooty libs.

2. Coal energy is now more expensive than wind and solar.

3. So this means: higher energy prices, more pollution, no jobs benefit. Genius!
atrupar.com
Energy Secretary Chris Wright on Fox: "We're announcing today expanded programs to help the American coal industry. We're helping it because for years it has been under assault. It was out of fashion with the chardonnay set in San Francisco, Boulder, and NYC ... coal just makes the world go round."