Lucas Nivon
@lucasnivon.bsky.social
400 followers 1K following 160 posts
CEO and co-founder at Cyrus Bio. Co-founder OpenFold AI bio consortium. Computational protein/biologic discovery. Rare disease, auto-immune, anti-viral, vax. PhD Harvard Biophys, Postdoc Bakerlab at UW. #Urbanism, #bikes, #democracy, #proteinai
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Reposted by Lucas Nivon
pushtheneedle.bsky.social
This is great and also illustrates how frivolous and completely damaging design review is for housing in our city
qagggy.bsky.social
The project at 118 W. Mercer Street is back! This is the project on the old Tup Tim Thai site that was brutally murdered by Design Review and left a smoldering ruin in the heart of Uptown.
lucasnivon.bsky.social
Thank you for posting, this has been such a weird gap in the street on Mercer. What a senseless saga of housing
lucasnivon.bsky.social
Explaining #seattle housing politics to a New Yorker is hilarious. nimby position is new buildings only downtown. The far left most yimby position is brownstone height buildings near commercial centers. The notion of brownstone height everywhere or some taller buildings is outside polite discourse.
Reposted by Lucas Nivon
synbiogaolab.bsky.social
Having often dealt with the frustration of binder-limited projects, we sought a more accessible source for nanobodies than yeast display or llama. Here we introduce Germinal, computationally designing antibody-like binders with such a hit rate that only tens need to be screened for each target.
lucasnivon.bsky.social
I’d buy a sign! Feels strange to only see the nimby signs around
lucasnivon.bsky.social
Is there an opposing group “Queen Anne for more neighbors” or “Queen Anne for the people”?
lucasnivon.bsky.social
One of the densest places in the world has ladder streets. Seems doable in QA. en.wikipedia.org/wiki/Ladder_...
Ladder streets - Wikipedia
en.wikipedia.org
Reposted by Lucas Nivon
amunts.bsky.social
Speak up to prevent a major loss for the field. CASP, which helped shaping structural biology including AlphaFold is on the verge of shutting down. NIH funding has lapsed, UC Davis support ends and the core team is being let go. Painfully shortsighted.
Exclusive: Famed protein structure competition nears end as NIH grant money runs out
Agency silent on funding renewal for contest that inspired creation of AIs that predicted how proteins would fold
www.science.org
Reposted by Lucas Nivon
brenttoderian.bsky.social
“Someone with a 1-hr car commute needs to earn 40% more to be as happy as someone with a short walk to work. On the other hand, if someone shifts from a long commute to a walk, their happiness increases as much as if they’d fallen in love.” #CityMakingMath

50 reasons to want more walkable cities.
50 Reasons Why Everyone Should Want More Walkable Streets
From making you live longer to making cities more resilient: If you want a reason to make your city more walkable, it's in here.
www.fastcompany.com
Reposted by Lucas Nivon
mollyknight.bsky.social
Job Garcia’s kidnapping by the Trump administration is the top story on the LA Times website right now.

www.latimes.com/california/s...
A 37-year-old U.S. citizen who was tackled to the ground and arrested after filming federal agents at Home Depot on Thursday said he was held for more than an hour near Dodger Stadium, where agents boasted about how many immigrants they arrested.
"How many bodies did you guys grab today?" he said one agent asked.
"Oh, we grabbed 31," the other replied.
"That was a good day today," the first agent responded.
The two high-fived, as Job Garcia sat on the asphalt under the sun, he said.
Garcia was released on Friday from a downtown federal detention center. No apparent criminal charges have yet to be filed. He is one of several U.S citizens arrested during enforcement operations in recent days. Department of Homeland Security officias sav some trave ilegaly 11:04 C
•ll 5G+ 824)
latimes.com
"You wanted it, you got it," the man yelled.
An agent handcuffed him so hard "that there was no circulation running to my fingers," Garcia said.
Pinned down, Garcia had difficulty breathing.
"That moment, I thought I could probably die here," he said.
The agent put Garcia's phone back in his pocket. The recording kept running.
As Garcia was put into a vehicle, his video captured an agent twice saying: "I've got one back here."
"You got one what?" Garcia shot back. "You got one what?"
He said an agent told him in broken Spanish to "wait here,' though it could not be heard on the video. - 11:04 €
• 5G+ 824)
latimes.com
"I f- speak English, you f- dumbass," he clearly shouts back.
No agent asked if he was an American citizen, he said. Nobody asked for identification.
"They assumed that I was undocumented," he said later in an interview.
The video ends after about four minutes, while he is waiting in the van.
CALIFORNIA
Raid at a Home Depot in Hollywood shatters an immigrant refuge
June 20, 2025
Garcia asked an agent to get his wallet from his car, so he could prove he was a U.S. citizen. Another agent retrieved his ID, but he remained handcuffed.
They were so tight, his hands hegan to swell. Garcia asked an agent to get his wallet from his car, so he could prove he was a U.S. citizen. Another agent retrieved his ID, but he remained handcuffed.
They were so tight, his hands began to swell.
The agents switched him to handcuffs that looked like shoelaces. They took off around a corner, stopped to shuffle him into another van and sped off down the 101 Freeway.
"I smeared my blood in their seat," he said.
And he thought, "They're going to remember me."
lucasnivon.bsky.social
One of the hardest things about growing up in #nyc and living elsewhere is the utter lack of Chinese Cuban restaurants #iykyk… Trader Joe’s plantains scratch that itch
Reposted by Lucas Nivon
seattleindivisible.bsky.social
Excited to announce that Pramila Jayapal will be our featured speaker at the Rally before the JUNE 14th - Seattle NO KINGS MARCH.

#nokings #DefendDemocracy #FightAuthoritarians #NoFascism
Reposted by Lucas Nivon
Reposted by Lucas Nivon
drjanicekirsch.bsky.social
THE AMERICAN MEDICAL ASSOCIATION CALLS FOR A SENATE INVESTIGATION INTO RFK, JR.

"The resolution’s sponsor, Dr. Jason Goldman, urged his colleagues to support the request for an investigation to ensure the AMA is not “on the wrong side of history.”

chicago.suntimes.com/health/2025/...
Investigate federal vaccine panel's overhaul, AMA urges Senate
Health and Human Services Secretary Robert F. Kennedy Jr., a longtime skeptic of vaccinations, said he ousted the CDC committee to restore "public trust in vaccines."
chicago.suntimes.com
Reposted by Lucas Nivon
jonathancohn.bsky.social
"If there were justice in the world, Musk would never be able to repair his reputation, at least not without devoting the bulk of his fortune to easing the misery he’s engendered."

www.nytimes.com/2025/05/30/o...
Opinion | Elon Musk’s Legacy Is Disease, Starvation and Death
www.nytimes.com
Reposted by Lucas Nivon
chrismurphyct.bsky.social
This guy stole $10 million from the employees of his nursing home to buy himself a luxury yacht and Cartier watches. He PLED GUILTY.

And because his Mom gave Trump $1 million, he just got a pardon.

And this story barely makes the news today. WTF. www.nytimes.com/2025/05/27/u...
Trump Pardoned Tax Cheat After Mother Attended $1 Million Dinner
www.nytimes.com
lucasnivon.bsky.social
Interest rates too high? And new “uncertainty”
Reposted by Lucas Nivon
cyrilpedia.bsky.social
'(...) we could end up with completely new treatments for some of these conditions (or for subsets of patients therein), but no matter what we're going to learn a tremendous amount about the role of B cells in their etiologies, from several different angles all at once'
@dereklowe.bsky.social
Autoimmune Disease, Transformed?
www.science.org
lucasnivon.bsky.social
I think this is the most hyper local bluesky interaction I’ve had, bluesky lives!
lucasnivon.bsky.social
So they are not closing? I hope not. Also my neighborhood coffee, and really great cookies and coffee cake and pocha
Reposted by Lucas Nivon
cyrusbio.bsky.social
Cyrus's CEO, Lucas Nivon, is the keynote speaker for Nucleate Seattle’s Activator Demo Day! Join us to hear him speak about Life Sciences Commercialization on May 14th at the Allen Institute. #Seattle #Biotech #Innovation lu.ma/18yj2jg3?tk=...
Nucleate Seattle: 2025 Demo Day · Luma
Please join Nucleate Seattle in celebrating our 2025 Activator cohort at our Demo Day! We invite all biotech and bio-entrepreneurial enthusiasts of all stages…
lu.ma
lucasnivon.bsky.social
Good idea to try! We have been testing deep research against review papers it can’t access and been impressed by low error rate and ability to update w more recent data. I was a skeptic but those tests were convincing
Reposted by Lucas Nivon
amunts.bsky.social
The structure of human sweetness: Cell
Sweet receptor bound to two widely used artificial sweeteners: sucralose and aspartame. A single receptor that mediates all our responses to sweet-tasting compounds.
lucasnivon.bsky.social
Thanks for attending! My neighbors in upper QA are incensed by the changes. Apartments are just terrible to them. And I’m too busy to attend meetings w retirees