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Reposted by Emily Podany MD

Rheum Cat @rheumcat.bsky.social · Apr 4

To live in this world

you must be able
to do three things:
to love what is mortal;
to hold it

against your bones knowing
your own life depends on it;
and, when the time comes to let it
go,
to let it go.

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Emily Podany MD @podanymd.bsky.social · Feb 28

#medsky #oncsky #BreastCancer #equity #disparities #cancer #publichealth

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Reposted by Emily Podany MD

Martin Michaelis (he/him) @martmichaelis.bsky.social · Feb 27

Inequities in #Cancer treatment. We need to make the world a fairer place. #BreastCancer #equity #Equality #MedSky #PoliSky 🧪

Racial Differences in ctDNA Profiles and Therapy in Metastatic Breast Cancer

This cohort study evaluates whether genomic profiles and targeted treatment use differ between Black and White patients with metastatic breast cancer.

jamanetwork.com

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Emily Podany MD @podanymd.bsky.social · Feb 28

I am very lucky to have the mentorship of Andrew Davis, Massimo Cristofanilli, Aditya Bardia, William Gradishar, and Cynthia Ma, among others. They have supported me every step of the way and I am forever grateful to them and all the incredible people who worked on this project with me.

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Emily Podany MD @podanymd.bsky.social · Feb 28

What do we do now that we have identified this disparity in targeted treatment use? We will evaluate the potential root causes and design interventions to address this gap. In the era of precision oncology, we must ensure patients equitably receive the recommended ctDNA-guided treatments. (5/5)

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Emily Podany MD @podanymd.bsky.social · Feb 28

Despite treatment advances, we also found that Black patients with metastatic breast cancer continue to have shorter survival compared to White patients, measured from time of ctDNA. This reflects the persistent and striking nationwide racial outcomes disparity in breast cancer. (4/5)

Two Kaplan Meier curves that show that Black patients have a shorter survival after ctDNA testing compared with White patients. Black patients with progesterone receptor negative metastatic breast cancer have the shortest survival.

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Emily Podany MD @podanymd.bsky.social · Feb 28

We found that Black patients with metastatic breast cancer were significantly less likely to receive PI3K inhibitors - the medications that can be given to patients with PIK3CA variants - than White patients (5.9% vs 28.8%). This disparity was despite the same % of PIK3CA mutations. (3/5)

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Emily Podany MD @podanymd.bsky.social · Feb 28

We found racial differences in variant frequency - higher rates of GATA3 and CCND2 variants in Black patients with MBC - by ctDNA which were validated in a large real-world cohort. But no differences in the targetable mutation PIK3CA, so we studied treatment equity next. (2/5)

A graphical depiction of differences in genomic findings between Black and White patients with metastatic breast cancer. It shows that Black patients have a higher rate of CCND2 and GATA3 variants.

A graph depicting racial differences in ctDNA findings in a large real world cohort. There are many differences, but it supports the finding that Black patients have a higher rate of CCND2 and GATA3 compared with White patients.

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Emily Podany MD @podanymd.bsky.social · Feb 28

Out now in @jama.com Network Open: We evaluated racial differences in ctDNA profiles and disparities in targeted treatment use and outcomes in metastatic breast cancer in a large multi-institution cohort. (1/5) jamanetwork.com/journals/jam...

Racial Differences in ctDNA Profiles and Therapy in Metastatic Breast Cancer

This cohort study evaluates whether genomic profiles and targeted treatment use differ between Black and White patients with metastatic breast cancer.

jamanetwork.com

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Reposted by Emily Podany MD

Dr Rageshri Dhairyawan @drrageshri.bsky.social · Feb 14

✨My essay in @thelancet.bsky.social this week has made the front page!✨ (I didn’t know about this 🤗)

‘Reflect, Collaborate and Listen’ looks at why doctors don’t listen and the urgent need to rebalance the power dynamic in the patient - doctor relationship.

www.thelancet.com/journals/lan...

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Reposted by Emily Podany MD

Paolo Tarantino, MD @ptarantinomd.bsky.social · Feb 15

2025 is anticipated to be the year with the highest number of phase 3 ADC trials read outs in breast oncology, with impact for all breast cancer subtypes.

Here’s 8 ADC breast cancer trials expected to reshape practice in 2025:

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Reposted by Emily Podany MD

Stephanie L. Graff, MD FACP FASCO @drsgraff.bsky.social · Jan 27

🧵Welcome to a fun & informative 3-part #BlueThread on how to make 🎯decisions in HR+, HER2- #MBC, based on a case-based #CME activity I developed with @peerview.bsky.social 👉 PeerView.com/AGR. I’ll post 3 case scenarios with a poll ? 📊, you vote 📲, and we’ll discuss each case. Ready?

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Reposted by Emily Podany MD

Nick Pannunzio @pannunziolab.bsky.social · Jan 26

Now more than ever it's important for communities that support science to band together. The future of cancer health disparity research in the US is in jeopardy. If you're interested in connecting to other disparities researchers on bsky, I can add you to this starter pack 💪🧬🩸💉🔬

go.bsky.app/HyLFqvg

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Reposted by Emily Podany MD

Society of General Internal Medicine (SGIM) @societygim.bsky.social · Dec 17

Drs. Podany, Bhayani, and Patel share advice for physician parents, drawing on their experiences as physician moms and caregiver initiative leaders. They remind us: "Humans were never meant to parent in a vacuum." Let’s support parents in medicine! #SGIMForum #WomenInMedicine

Parenting in Medicine: Navigating Your Way to Work-Life Integration – SGIM

Doctors face unique challenges when starting a family and balancing parenthood with work. In a study of more than 1,000 female physicians, 75% delayed starting their family due to training or work,…

buff.ly

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Reposted by Emily Podany MD

Toni Choueiri, MD @drchoueiri.bsky.social · Nov 30

Our latest in @naturecomms.bsky.social from @danafarber.bsky.social / @mskcc.bsky.social collaboration: AI to extract cancer outcomes in EMR!

www.nature.com/articles/s41...

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Reposted by Emily Podany MD

Ian Davis @profiand.bsky.social · Nov 28

I've decided that when researchers say a treatment is "well tolerated" it actually means "I can tolerate my patients having toxicity" and nothing to do with what the patient thinks. We can only make such a statement if we use patient-reported outcome or experience measures.

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Reposted by Emily Podany MD

JAMA @jama.com · Nov 28

Cervical cancer mortality decreased 15.2% per year from 2013-2015 to 2019-2021, suggesting HPV vaccination has affected the sequential decline in HPV infection prevalence, cervical cancer incidence, and cervical cancer mortality.

Read the research letter: ja.ma/4185MWu

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Reposted by Emily Podany MD

Paolo Tarantino, MD @ptarantinomd.bsky.social · Nov 25

Regular abstracts from #SABCS24 are out!

3407 pages of new breast cancer discoveries.

Find them here: sabcs.org/Portals/0/Do...

sabcs.org

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Reposted by Emily Podany MD

Amanda Hills Podany @ahpodany.bsky.social · Nov 25

Paw prints prove that good boys and girls have been casually walking across wet concrete (actually drying Mesopotamian mudbricks, in this case) for thousands of years. (Penn Museum B16461, Hearst Museum PAHMA 9-1765, VA Bab 04060.005, British Museum 137495)

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Reposted by Emily Podany MD

Paolo Tarantino, MD @ptarantinomd.bsky.social · Nov 17

Only 3 weeks to #SABCS24, a meeting that promises to significantly impact the way we treat breast cancer. It will feature phase 3 data with novel SERDs, novel ADCs, immunotherapy, ctDNA monitoring, important biomarker analyses & so much more. Here’s my top 10 abstracts list— see you in San Antonio!

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Reposted by Emily Podany MD

Shikha Jain MD FACP @shikhajainmd.bsky.social · Nov 21

go.bsky.app/4pWmu3W

Share who you think should be added! 👇🏽👇🏽👇🏽👇🏽👇🏽

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Reposted by Emily Podany MD

SF Said @whatsfsaid.bsky.social · Nov 18

Never forget: READING FOR PLEASURE has the biggest positive impact of any factor on children's life chances. So never stop sharing books with kids. Never stop reading to them, and helping them to read. Never stop changing lives. #literacy #kidlit #books

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Amy Johnston, PhD @amydjohn.bsky.social · Nov 19

Percentage of women authors (Web of Science data):

Countries in Orange have gender parity 👀

#AcademicSky #WomenInSTEM #GenderSummit2024

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Reposted by Emily Podany MD

Rana Awdish MD @ranaawdish.bsky.social · Nov 19

Is sharing our writing a thing here? 😊
Proud of this piece because it represents the work of so many trying to make medicine and communication better for our patients. #MedSky
www.mayoclinicproceedings.org/action/showP...

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Emily Podany MD @podanymd.bsky.social · Nov 8

I love this thread! Hi 👋 I'm Emily, finishing heme/onc fellowship and an MPHS in July. I'm interested in health disparities in breast cancer, social justice, public health, and improving treatment equity using implementation science.

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