Terence McSweeney
@termcs.bsky.social
52 followers 94 following 16 posts
Doctoral researcher: AI, medical imaging, radiomics, spine and low back pain MOst Osteopathy, MSc Pain Management, Ireland-USA Fulbright 2024 Also cycling, running, and a bit of jiu jitsu. Living in Oulu, Finland 🇫🇮
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termcs.bsky.social
Really sad news. What a huge loss. Ar dheis Dé go raibh a anam dílis.
Reposted by Terence McSweeney
saoirsemc.bsky.social
A massive loss to us all. His care for and wonder at both nature and the Irish language was a great gift that he shared with us all
Reposted by Terence McSweeney
hsu-prof-msk-sv.bsky.social
Twenty-five years ago, I had the privilege of working with an exceptional group of researchers on what would become a great study about low back pain care and practice. The same team have revisited this. Fascinating results bmcmusculoskeletdisord.biomedcentral.com/articles/10....
Testing the effectiveness of an innovative information package on practitioner reported behaviour and beliefs: The UK Chiropractors, Osteopaths and Musculoskeletal Physiotherapists Low back pain ManagemENT (COMPLeMENT) trial [ISRCTN77245761] - BMC Musculoskeletal Disorders
Background Low back pain (LBP) is a common and costly problem. Initiatives designed to assist practitioner and patient decisions about appropriate healthcare for LBP include printed evidence-based clinical guidelines. The three professional groups of chiropractic, osteopathy and musculoskeletal physiotherapy in the UK share common ground with their approaches to managing LBP and are amongst those targeted by LBP guidelines. Even so, many seem unaware that such guidelines exist. Furthermore, the behaviour of at least some of these practitioners differs from that recommended in these guidelines. Few randomised controlled trials evaluating printed information as an intervention to change practitioner behaviour have utilised a no-intervention control. All these trials have used a cluster design and most have methodological flaws. None specifically focus upon practitioner behaviour towards LBP patients. Studies that have investigated other strategies to change practitioner behaviour with LBP patients have produced conflicting results. Although numerous LBP guidelines have been developed worldwide, there is a paucity of data on whether their dissemination actually changes practitioner behaviour. Primarily because of its low unit cost, sending printed information to large numbers of practitioners is an attractive dissemination and implementation strategy. The effect size of such a strategy, at an individual practitioner level, is likely to be small. However, if large numbers of practitioners are targeted, this strategy might achieve meaningful changes at a population level. Methods The primary aim of this prospective, pragmatic randomised controlled trial is to test the short-term effectiveness (six-months following intervention) of a directly-posted information package on the reported clinical behaviour (primary outcome), attitudes and beliefs of UK chiropractors, osteopaths and musculoskeletal physiotherapists. We sought to randomly allocate a combined sample of 1,800 consenting practitioners to receive either the information package (intervention arm) or no information above that gained during normal practice (control arm). We collected questionnaire data at baseline and six-months post-intervention. The analysis of the primary outcome will assess between-arm differences of proportions of responses to questions on recommendations about activity, work and bed-rest, that fall within categories previously defined by an expert consensus exercise as either 'guideline-consistent' and 'guideline-inconsistent'.
bmcmusculoskeletdisord.biomedcentral.com
Reposted by Terence McSweeney
Reposted by Terence McSweeney
princess-vimentin.bsky.social
That feeling when you do all this work for this ONE piece of data for your story and the results don’t exactly fit the way you want it to…🧪🧫
Tetris game depicting that many things in life don’t work out as you envision. 

Sometimes the data from experiments don’t fit perfectly with your story.
Reposted by Terence McSweeney
biomech.siril.me
Thrilled to share that my latest research has been published in IEEE Transactions on Biomedical Engineering!

"Evaluation of a Fast-Solving Rigid Body Spine Model Inclusive of Intra-Abdominal Pressure"

ieeexplore.ieee.org/document/109...

#biomechanics #spine #orthopaedics #digitaltwin #robotics
Reposted by Terence McSweeney
issls.bsky.social
Great special poster session this morning #ISSLS2025 on #IVD degeneration chaired by Stefan Dudli and Kotaro Nishida
termcs.bsky.social
Strange being at a conference #ISSLS2025 without twitter/x and without bsky as an effective alternative. Would be great if the community could engage again here on bsky…
Reposted by Terence McSweeney
issls.bsky.social
Presenters are getting robust and constructive questioning here very much in the spirit of #ISSLS2025! Halfway through a great session here including studies on #Modicchanges and deep learning spine variables extracted from UK biobank
Reposted by Terence McSweeney
issls.bsky.social
#ISSLS2025 has officially kicked off here in Atlanta with the basic science session!
Reposted by Terence McSweeney
abeba.bsky.social
this is unsustainable. data centers in Ireland already consume over 20% of the total energy the country produces (the highest in Europe)
termcs.bsky.social
I thought spring would start for me at the Lahti 200k last weekend…
termcs.bsky.social
A comprehensive review of cell transplantation and platelet-rich plasma therapy for the treatment of disc degeneration-related back and neck pain. A really nice review @jordyschol.bsky.social 👏🏻
jorspine.bsky.social
Check out this recent review by Jordy Schol & coauthors, which highlights the clinical significant differences obtainable through cell and PRP injections against #backpain: onlinelibrary.wiley....
Illustration presenting the general structure of the intervertebral disc (IVD) and the impact of disc degeneration and cell therapy-derived regeneration. (A) A healthy IVD as an entire unit, including the nucleus pulposus (NP), annulus fibrosis (AF), and vertebra with facet-joints. (B) Progression of disc degeneration illustrated by loss of matrix quality, AF-organization, loss of endplate permeability, and NP cell viability and activity, which in turn may promote nerve ingrowth. (C) Transplantation of de novo cells or PRP products into the disc, vertebrae, or epidural space, may support (D) regeneration of the IVD as hallmarked by improvement in cell quantity and quality, tissue organization, nerve ingrowth and sensitization, biomechanical features, and disc features such as height and hydration. AF, anulus fibrosus; IVD, intervertebral disc; NP, nucleus pulposus; PRP, platelet-rich plasma.
Reposted by Terence McSweeney
Reposted by Terence McSweeney
altmetric.com
THREAD

The numbers are in. @bsky.app research sharing volumes vs X Formerly Twitter

In March 2024, on most days, Bluesky hosts more posts linked to research published in 2025 than X.

By quite a lot.

Release the Kraken...

#AcademicSky #HigherEd #Altmetrics
1/11
Butterflies on a blue sky
termcs.bsky.social
Similar in Irish, vocabulary is 'stór focal'. Stór means store, but also treasure, e.g. referring to a loved one as 'a stóirín', my little treasure.
Reposted by Terence McSweeney
psalmotoxin.bsky.social
Cool overview of #osteoarthritis, which will be of interest to many in #neuroskyence & #PainResearch communities. Thanks to @tuhinaneogi.bsky.social, @jointsintheworld.bsky.social & others!

Some figures that will doubtless appear in many talks in years to come!

www.nature.com/articles/s41...
This figure shows the healthy joint (part a) and osteoarthritic joint (part b). Almost all tissue structures in osteoarthritis joint tissues show pathological changes, including articular cartilage degradation, fibrosis and inflammation of the synovium and infrapatellar fat pad, subchondral bone remodelling, meniscal damage and ligament damage. This figure outlines the hierarchical relationship between individual-level (influenced by genetic, systemic and lifestyle factors) and joint-level (specific to joint anatomy and function) risk factors that contribute to the susceptibility, progression and burden of osteoarthritis. Modifiable risk factors (blue) and non-modifiable risk factors (red) are also displayed. Knee osteoarthritis is one of the most common joint diseases, characterized by pathological changes that involve the degradation of articular cartilage, inflammation and fibrosis of the synovium and infrapatellar fat pad, and remodelling of the subchondral bone. Cartilage degradation is driven by the excessive activity of matrix metalloproteinases (MMPs) and ADAMTS enzymes, leading to the breakdown of collagen and proteoglycans, resulting in cartilage becoming thinner and cracked, compromising its cushioning function, and causing joint pain and stiffness. Meanwhile, synovial tissue shows chronic inflammation, including congestion, synovial cell hyperplasia and inflammatory cell infiltration, increasing inflammatory factors in the synovial fluid and further damaging the cartilage. The infrapatellar fat pad is also affected, with fibrosis potentially altering mechanical properties around the joint, affecting movement. The subchondral bone undergoes significant structural changes such as sclerosis and abnormal remodelling, which can lead to osteophyte formation, altering joint mechanics and increasing cartilage load. The sclerosis changes stress distribution within the joint, exacerbating cartilage damage. These pathological processes are interconnected, forming a complex network where inflammatory factors, such as IL-1β, IL-6 and TNF, further promote cartilage degradation and synovial inflammation. Mechanical stress signals activate chondrocytes and bone cells, accelerating lesion progression. Senescence-associated secretory phenotype (SASP) factors from chondrocytes or matrix-degrading enzymes secreted by osteoclasts and synovium/fat pad cells interact to exacerbate tissue damage, highlighting the importance of understanding these cellular and molecular interactions for effective osteoarthritis treatment. ARGS, aggrecanase generated aggrecan amino acids alanine, arginine, glycine, serine. a, Overview of the peripheral pain pathway in joint pain. Noxious stimuli activate the peripheral terminals of nociceptors that innervate joint tissues. Depolarization of nerve terminals initiates the firing of action potentials that invade the dorsal root ganglia, where the cell bodies reside. This requires the activation of voltage-gated sodium channels NaV1.7, NaV1.8 and NaV1.9. Signals are transmitted to the dorsal horn of the spinal cord, where nociceptors synapse with second-order neurons — either interneurons (not shown) or projection neurons that cross to the contralateral side and carry the signal up the spinal cord. From there, the signals are propagated to higher regions of the central nervous system and different areas of the brain, where they are perceived as pain. b, Peripheral terminals of nociceptors express voltage-gated sodium channels and ion channels, such as TRPV1, or mechanosensitive ion channels such as Piezo2. They also express receptors for inflammatory mediators released by degrading and inflamed joint tissues, such as nerve growth factor (NGF), CCL2 or disease-associated molecular patterns (DAMPs). c, Anatomical neuroplasticity occurs as part of osteoarthritis pathology, including neo-innervation of the synovium and sprouting of nociceptors in the subchondral bone, which may breach the tidemark.
Reposted by Terence McSweeney
vph-i.bsky.social
✈️ The VPHi will award up to 2 travel vouchers to support deserving student members with travel and accommodation costs for the Summer School in Barcelona! 🇪🇸

Learn more and apply here 👉 www.vph-institute.org/news/vphi-tr...
#SummerSchool #TravelVoucher
termcs.bsky.social
This is amazing, I hope it continues to improve. I lived in central London from 2007-2014 and cycled everywhere so judging from this I got the worst of it 😆
liammcgrath.bsky.social
tfl.gov.uk/corporate/pu... huge amounts of data on reductions in air pollution in London in part due to ULEZ.
Figure 8 of the ULEZ monitoring report March 2025. NO2 Levels by monitoring site, showing large reductions.
termcs.bsky.social
Looks like a comprehensive study looking forward to reading it. Am very curious about the T2 weighted MRI method they used given the challenges not least the big voxels.
asafklaf.bsky.social
New study finds evidence for neuroinflammation in the periphery of individuals after WHIPLASH. Very well conducted study! Sample size ✅ control group ✅ Sig. findings on MRI ✅ Sig. findings on blood tests ✅ Sig. findings on QST ✅

#physio
#neuroskyence
#painresearch
🧪🛟
Evidence for peripheral neuroinflammation after acute... : PAIN
a subgroup with underlying nerve involvement in WADII, such as peripheral neuroinflammation. This study aimed to investigate the presence of neuroinflammation in acute WADII using T2-weighted magnetic...
journals.lww.com
termcs.bsky.social
I find their presence somehow reassuring…
termcs.bsky.social
Didn’t own a car for the 4 years I lived in Swansea and got around by bike but wasn’t the best. Spoilt in Oulu now, even in the miserable ice slush conditions here today the delivery robots can manage on the bike paths.