Yi Yang
@ohrp.bsky.social
710 followers 3.5K following 9 posts

Environmental Microbiologist Anaerobic microbiology Organohalide-respiring bacteria OHRP https://orcid.org/0000-0002-3519-5472 https://scholar.google.com/citations?user=6bry4AgAAAAJ&hl=en

Environmental science 63%
Geography 17%
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ohrp.bsky.social
“Candidatus Dehalogenimonas loeffleri” pubs.acs.org/doi/10.1021/...
Dehalogenimonas Strain W from Estuarine Sediments Dechlorinates 1,2-Dichloroethane under Elevated Salinity
Organohalide-respiring bacteria (OHRB) have been found in various environments and play an indispensable role in the biogeochemical cycling and detoxification of halogenated organic compounds (HOCs). Currently, few ORHB have been reported to perform reductive dechlorination under high salinity conditions, indicating a knowledge gap on the diversity of OHRB and the survival strategy of OHRB in saline environments (e.g., estuarine, marine). This study reports the characterization of an enrichment culture dominated by a new Dehalogenimonas population strain W derived from estuarine sediments, which demonstrates the capability to dechlorinate 1,2-dichloroethane (1,2-DCA) to ethene under elevated salinity (≥5.1% NaCl, w/v). Metagenomic and proteomic analyses revealed that the distinctive high-salinity dechlorination of strain W is primarily attributed to a putative reductive dehalogenase (RDase) DdeA, which shares >91.4% amino acid identity with the dihaloeliminating RDase DcpA from other Dehalogenimonas strains. Additionally, ectoine biosynthesis enzymes (EctABC) contribute to the strain’s salt tolerance. These findings underscore the potential of OHRB, particularly Dehalogenimonas, to detoxify HOCs in high-salinity environments, such as estuarine and marine ecosystems, by employing compatible solutes as an adaptive mechanism.
pubs.acs.org

Reposted by Yi Yang

Reposted by Yi Yang

Reposted by Yi Yang

katherinecaley.bsky.social
🐍🌲 piqtree: IQ-TREE2 meets Python via cogent3! 🤝⚡️

The developers of IQ-TREE2 and cogent3 have joined forces to bring the power of IQ-TREE2 to Python users as piqtree.

piqtree exposes selected IQ-TREE2 capabilities within Python, using the cogent3 library as the interface...
piqtree: IQ-TREE2 meets Python via cogent3 · iqtree piqtree · Discussion #145
The developers of IQ-TREE2 and cogent3 have joined forces to bring the power of IQ-TREE2 to Python users as piqtree. piqtree exposes selected IQ-TREE2 capabilities within Python, using the cogent3 ...
github.com

Reposted by Yi Yang

Reposted by Yi Yang

rrwick.bsky.social
New release of Canu - first one in over 3 years!
github.com/marbl/canu/r...

The notes say this will be the very last release. Many thanks to its devs Brian Walenz and @sergek.bsky.social. Canu may be a bit old and it's certainly not fast, but it makes good assemblies and so I still use it!
Release Canu v2.3 · marbl/canu
These are release notes for Canu version 2.3, which was released on December 17th, 2024. Canu is specialized for assembly of single-molecule sequences. Full documentation can be found at http://can...
github.com

Reposted by Yi Yang

sbgrid.bsky.social
New Title Alert: Boltz-1- an open-source model which predicts the 3D structure of proteins, rna, dna and small molecules; it handles modified residues, covalent ligands & glycans.

Learn more here: https://buff.ly/3ZAPowA

#SBGridSoftware #SBGrid
GitHub - jwohlwend/boltz: Official repository for the Boltz-1 biomolecular interaction model
Official repository for the Boltz-1 biomolecular interaction model - jwohlwend/boltz
buff.ly

typaslab.bsky.social
You want to learn about microbiology from a fantastic lineup of speakers on a beautiful Greek island? PhD students apply now for the @EMBO | @FEBSnews Lecture Course The New Microbiology!
Registration: 1 Apr 2025
Course: 03 – 11 Sep 2025 | Spetses, Greece
meetings.embo.org/event/25-new...

Reposted by Yi Yang

events.embl.org
Hi Bluesky community! 👋

Are you looking forward to 2025 as much as we are? 👀

We just updated our 2025 Annual Poster to include even more events for you to join, so go and have a look!

➡️ s.embl.org/poster-bl

#EMBLEvents #molecularbiology #lifesciencetraining
The 2025 EMBL Annual Poster, listing all of the courses and conferences taking place in 2025 at EMBL

Reposted by Yi Yang