Akul Mehta
@akulmehta.bsky.social
310 followers
430 following
49 posts
Glycoscientist @theNCFG BIDMC-Harvard Medical School
π¨βπ»π¨βπ¬β½π·
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Reposted by Akul Mehta
Reposted by Akul Mehta
Reposted by Akul Mehta
Akul Mehta
@akulmehta.bsky.social
Β· 25d
Akul Mehta
@akulmehta.bsky.social
Β· 26d
Reposted by Akul Mehta
I'm a huge fan of this proposal!
If we can get vendor buy-in to an open, common format, it could bring more computational folks into the field. How can these folks be excited about #proteomics when its hard to even read the already complicated data?
pubs.acs.org/doi/10.1021/...
If we can get vendor buy-in to an open, common format, it could bring more computational folks into the field. How can these folks be excited about #proteomics when its hard to even read the already complicated data?
pubs.acs.org/doi/10.1021/...
mzPeak: Designing a Scalable, Interoperable, and Future-Ready Mass Spectrometry Data Format
Advances in mass spectrometry (MS) instrumentation, including higher resolution, faster scan speeds, and improved sensitivity, have dramatically increased the data volume and complexity. The adoption of imaging and ion mobility further amplifies these challenges in proteomics, metabolomics, and lipidomics. Current open formats such as mzML and imzML struggle to keep pace due to large file sizes, slow data access, and limited metadata support. Vendor-specific formats offer faster access but lack interoperability and long-term archival guarantees. We here lay the groundwork for mzPeak, a next-generation community data format designed to address these challenges and support high-throughput, multidimensional MS workflows. By adopting a hybrid model that combines efficient binary storage for numerical data and both human- and machine-readable metadata storage, mzPeak will reduce file sizes, accelerate data access, and offer a scalable, adaptable solution for evolving MS technologies. For researchers, mzPeak will support complex workflows and regulatory compliance through faster access, improved metadata, and interoperability. For vendors, it offers a streamlined, open alternative to proprietary formats. mzPeak aims to become a cornerstone of MS data management, enabling sustainable, high-performance solutions for future data types and fostering collaboration across the mass spectrometry community.
pubs.acs.org
Akul Mehta
@akulmehta.bsky.social
Β· 29d
Akul Mehta
@akulmehta.bsky.social
Β· 29d
π€― Did you know proteins inside cells can be glycosylated?! π¬ Our latest blog post dives into the surprising world of intra-cellular protein glycosylation & its vital role in biology!
π research.bidmc.org/ncfg/blog/21...
#glycans #glycosylation #posttranslationalmodification #glycotime
π research.bidmc.org/ncfg/blog/21...
#glycans #glycosylation #posttranslationalmodification #glycotime
21] Facts About: Intracellular Protein Glycosylation
research.bidmc.org
Reposted by Akul Mehta
Daniel Bojar
@dbojar.bsky.social
Β· Sep 30
Arcaneering: Beyond Automation on Steam
Automate the arcane! Build spell-powered factories, reclaim ancient territories filled with magical secrets, and discover game-changing technology hidden across procedurally generated worlds. Master b...
store.steampowered.com
Reposted by Akul Mehta
Elisa Fadda
@elisafadda.bsky.social
Β· Sep 16
Regulation of N-glycosylation efficiency by eukaryotic oligosaccharyltransferase - Glycopedia
Oligosaccharyltransferase (OST) catalyses the key step of N-glycosylation, transferring immature N-glycans to select Asn residues in nascent proteins in the endoplasmic reticulum (ER). Asn are more li...
glycopedia.eu
Akul Mehta
@akulmehta.bsky.social
Β· Sep 16
Akul Mehta
@akulmehta.bsky.social
Β· Sep 16
Akul Mehta
@akulmehta.bsky.social
Β· Sep 16
Akul Mehta
@akulmehta.bsky.social
Β· Sep 16
Akul Mehta
@akulmehta.bsky.social
Β· Sep 16
Akul Mehta
@akulmehta.bsky.social
Β· Sep 16
Akul Mehta
@akulmehta.bsky.social
Β· Sep 16
Akul Mehta
@akulmehta.bsky.social
Β· Sep 16
Akul Mehta
@akulmehta.bsky.social
Β· Sep 16
Akul Mehta
@akulmehta.bsky.social
Β· Sep 16