Amanda Ali
@amandality.bsky.social
At the helm of the Ali Lab, studying all things osteoarthritis | Assistant Scientist/Professor @HFH+MSU | Postdoc @UHN | Postdoc @UWO | PhD @UofT | Guyanese-Canadian | Mama
Special seminar today at @hfhs-bjc.bsky.social by Dr. Nathaly Villacis, who will be visiting from the University of Michigan. The title of her talk is “Towards Rotator Cuff Tendon Digital Twins: A Three-Dimensional Experimental and Computational Approach”.
February 10, 2026 at 4:07 PM
Special seminar today at @hfhs-bjc.bsky.social by Dr. Nathaly Villacis, who will be visiting from the University of Michigan. The title of her talk is “Towards Rotator Cuff Tendon Digital Twins: A Three-Dimensional Experimental and Computational Approach”.
"Don't ignore the problem, but keep it light. Take action with a smile. Adding tension won't solve your troubles faster.
Even when the problem is hard, it doesn't need to harden you. Unknot yourself. Body loose, head clear, and then take the first step.
Be happy in the doing."
James Clear
Even when the problem is hard, it doesn't need to harden you. Unknot yourself. Body loose, head clear, and then take the first step.
Be happy in the doing."
James Clear
February 6, 2026 at 8:10 PM
"Don't ignore the problem, but keep it light. Take action with a smile. Adding tension won't solve your troubles faster.
Even when the problem is hard, it doesn't need to harden you. Unknot yourself. Body loose, head clear, and then take the first step.
Be happy in the doing."
James Clear
Even when the problem is hard, it doesn't need to harden you. Unknot yourself. Body loose, head clear, and then take the first step.
Be happy in the doing."
James Clear
Reposted by Amanda Ali
As we usher in the new year, we also wanted to celebrate the achievements of a giant in the hashtag#osteoarthritis community.
Read more about Frank's legacy and the Frank Beier Graduate Opportunity Scholarship in this month's issue here: www.oarsijournal.com/article/S106...
Read more about Frank's legacy and the Frank Beier Graduate Opportunity Scholarship in this month's issue here: www.oarsijournal.com/article/S106...
January 12, 2026 at 1:19 AM
As we usher in the new year, we also wanted to celebrate the achievements of a giant in the hashtag#osteoarthritis community.
Read more about Frank's legacy and the Frank Beier Graduate Opportunity Scholarship in this month's issue here: www.oarsijournal.com/article/S106...
Read more about Frank's legacy and the Frank Beier Graduate Opportunity Scholarship in this month's issue here: www.oarsijournal.com/article/S106...
Reposted by Amanda Ali
Defending PhD student, looking over their thesis: “If I knew then what I know now, I could’ve done all of this in like 9 months.”
A thread about my favorite pioneering cave explorers and why I don’t think AI will ever “solve” biology.
A thread about my favorite pioneering cave explorers and why I don’t think AI will ever “solve” biology.
January 11, 2026 at 9:27 PM
Defending PhD student, looking over their thesis: “If I knew then what I know now, I could’ve done all of this in like 9 months.”
A thread about my favorite pioneering cave explorers and why I don’t think AI will ever “solve” biology.
A thread about my favorite pioneering cave explorers and why I don’t think AI will ever “solve” biology.
Reposted by Amanda Ali
Solid advice.👇
There. Is. No. Magic.
Move. Eat real food. Sleep. Don't smoke. Drink less (or not at all). Prevention (yep, vaccines). Community!! ♥️
Trying to improve your health and wellness in 2026? Keep it simple apnews.com/article/well...
There. Is. No. Magic.
Move. Eat real food. Sleep. Don't smoke. Drink less (or not at all). Prevention (yep, vaccines). Community!! ♥️
Trying to improve your health and wellness in 2026? Keep it simple apnews.com/article/well...
Trying to improve your health and wellness in 2026? Keep it simple
If you want to improve your health in 2026, experts say keep it simple. Be cautious of health and wellness fads. There are no magic fixes.
apnews.com
January 6, 2026 at 5:12 PM
Solid advice.👇
There. Is. No. Magic.
Move. Eat real food. Sleep. Don't smoke. Drink less (or not at all). Prevention (yep, vaccines). Community!! ♥️
Trying to improve your health and wellness in 2026? Keep it simple apnews.com/article/well...
There. Is. No. Magic.
Move. Eat real food. Sleep. Don't smoke. Drink less (or not at all). Prevention (yep, vaccines). Community!! ♥️
Trying to improve your health and wellness in 2026? Keep it simple apnews.com/article/well...
Reposted by Amanda Ali
Honored to share our new paper, Osteoarthritis as a Systemic Disease, in @natrevrheum.nature.com, out today: rdcu.be/eSXLW - thanks to Ida Haugen, @tuhinaneogi.bsky.social and @farsh-g.bsky.social for your input on gaps and opportunities.
Osteoarthritis as a systemic disease
Nature Reviews Rheumatology - Emerging evidence suggests a paradigm shift in viewing osteoarthritis (OA) as a systemic, bidirectional disease. This Review examines the current data supporting this...
rdcu.be
December 3, 2025 at 3:49 PM
Honored to share our new paper, Osteoarthritis as a Systemic Disease, in @natrevrheum.nature.com, out today: rdcu.be/eSXLW - thanks to Ida Haugen, @tuhinaneogi.bsky.social and @farsh-g.bsky.social for your input on gaps and opportunities.
"...former ANRF scholar Dr. Shabana Amanda Ali has published groundbreaking research that could detect osteoarthritis and rheumatoid arthritis before joint damage occurs..." www.nature.com/articles/s41...
Donate to the Arthritis National Research Foundation: secure.everyaction.com/DpkWeOy9n0ii...
Donate to the Arthritis National Research Foundation: secure.everyaction.com/DpkWeOy9n0ii...
November 26, 2025 at 11:59 PM
"...former ANRF scholar Dr. Shabana Amanda Ali has published groundbreaking research that could detect osteoarthritis and rheumatoid arthritis before joint damage occurs..." www.nature.com/articles/s41...
Donate to the Arthritis National Research Foundation: secure.everyaction.com/DpkWeOy9n0ii...
Donate to the Arthritis National Research Foundation: secure.everyaction.com/DpkWeOy9n0ii...
Reposted by Amanda Ali
welcome to bluesky. if the word "mapquest" means anything to you and/or you used it as a verb, you're in the right place
November 11, 2025 at 1:11 AM
welcome to bluesky. if the word "mapquest" means anything to you and/or you used it as a verb, you're in the right place
Reposted by Amanda Ali
Ridiculous. So maddening.
Yes, complex. But there is NO doubt that antivaxx misinformation big part of problem.
Canada loses measles elimination status after three decades, health agency says www.reuters.com/business/hea...
Yes, complex. But there is NO doubt that antivaxx misinformation big part of problem.
Canada loses measles elimination status after three decades, health agency says www.reuters.com/business/hea...
Canada loses measles elimination status after three decades, health agency says
Canada has lost its measles elimination status after nearly three decades due to its failure to curb a year-long outbreak, the country's public health agency said on Monday.
www.reuters.com
November 10, 2025 at 3:42 PM
Ridiculous. So maddening.
Yes, complex. But there is NO doubt that antivaxx misinformation big part of problem.
Canada loses measles elimination status after three decades, health agency says www.reuters.com/business/hea...
Yes, complex. But there is NO doubt that antivaxx misinformation big part of problem.
Canada loses measles elimination status after three decades, health agency says www.reuters.com/business/hea...
Reposted by Amanda Ali
Monthly #OARSI ECI Publication:
@amandality.bsky.social and her team identified miR-126-3p as a promising biomarker for knee #OA. It reduces angiogenesis and mitigates disease severity, supporting its potential as a therapeutic target.
@amandality.bsky.social and her team identified miR-126-3p as a promising biomarker for knee #OA. It reduces angiogenesis and mitigates disease severity, supporting its potential as a therapeutic target.
October 26, 2025 at 6:48 PM
Monthly #OARSI ECI Publication:
@amandality.bsky.social and her team identified miR-126-3p as a promising biomarker for knee #OA. It reduces angiogenesis and mitigates disease severity, supporting its potential as a therapeutic target.
@amandality.bsky.social and her team identified miR-126-3p as a promising biomarker for knee #OA. It reduces angiogenesis and mitigates disease severity, supporting its potential as a therapeutic target.
Reposted by Amanda Ali
🚨🚨 New Publication Alert: The Ali Lab published a review on advancements in genomics, genetics, and epigenetics of #osteoarthritis. Fantastic work Thomas Wilson, Madhu Baghel and @amandality.bsky.social!
www.oarsijournal.com/article/S106...
www.oarsijournal.com/article/S106...
Osteoarthritis year in review 2025: Genetics, genomics, and epigenetics
This review provides an overview of the work performed in the realms of genetics,
genomics and epigenetics in osteoarthritis (OA) research over the past year.
www.oarsijournal.com
September 20, 2025 at 2:08 PM
🚨🚨 New Publication Alert: The Ali Lab published a review on advancements in genomics, genetics, and epigenetics of #osteoarthritis. Fantastic work Thomas Wilson, Madhu Baghel and @amandality.bsky.social!
www.oarsijournal.com/article/S106...
www.oarsijournal.com/article/S106...
Reposted by Amanda Ali
Another great publication from @amandality.bsky.social and team! Sure does make one reconsider the old "wear and tear" hypothesis about #osteoarthritis. Exciting times in OA research!
🚨🚨 New Publication Alert: The Ali Lab published a review on advancements in genomics, genetics, and epigenetics of #osteoarthritis. Fantastic work Thomas Wilson, Madhu Baghel and @amandality.bsky.social!
www.oarsijournal.com/article/S106...
www.oarsijournal.com/article/S106...
Osteoarthritis year in review 2025: Genetics, genomics, and epigenetics
This review provides an overview of the work performed in the realms of genetics,
genomics and epigenetics in osteoarthritis (OA) research over the past year.
www.oarsijournal.com
September 20, 2025 at 2:10 PM
Another great publication from @amandality.bsky.social and team! Sure does make one reconsider the old "wear and tear" hypothesis about #osteoarthritis. Exciting times in OA research!
Truly an honor to be invited by #OARSI and @oacjournal.bsky.social to summarize all the amazing work in the genetics, genomics, and epigenetics of #osteoarthritis over the last year. A tough job with many great papers not included, but our review is now online: www.oarsijournal.com/article/S106...
September 20, 2025 at 2:40 AM
Truly an honor to be invited by #OARSI and @oacjournal.bsky.social to summarize all the amazing work in the genetics, genomics, and epigenetics of #osteoarthritis over the last year. A tough job with many great papers not included, but our review is now online: www.oarsijournal.com/article/S106...
All the right pieces in all the wrong places (also how I write grants).
Wordle 1,530 2/6
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August 28, 2025 at 2:36 AM
All the right pieces in all the wrong places (also how I write grants).
Wordle 1,530 2/6
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Kudos to Postdoc Madhu Baghel who led this project applying a custom sequencing analysis pipeline that included discovery of novel microRNAs in early-stage osteoarthritis and rheumatoid arthritis, laying a foundation for future biomarker studies. Read our paper here: www.nature.com/articles/s41...
August 9, 2025 at 2:31 AM
Kudos to Postdoc Madhu Baghel who led this project applying a custom sequencing analysis pipeline that included discovery of novel microRNAs in early-stage osteoarthritis and rheumatoid arthritis, laying a foundation for future biomarker studies. Read our paper here: www.nature.com/articles/s41...
Reposted by Amanda Ali
More miR-awesomeness from @amandality.bsky.social and team in the @hfhs-bjc.bsky.social! Great diagnostic potential for miR's in both #Osteoarthritis and #RheumatoidArthritis.
🚨🚨New publication alert! The Ali Lab @amandality.bsky.social in the @hfhs-bjc.bsky.social uses sequencing to profile microRNAs in early-stages of both osteoarthritis and rheumatoid arthritis! Now published in Scientific Reports @natureportfolio.nature.com, read it here: rdcu.be/eylic
Circulating microRNA profiles in early-stage osteoarthritis and rheumatoid arthritis
Scientific Reports - Circulating microRNA profiles in early-stage osteoarthritis and rheumatoid arthritis
rdcu.be
July 31, 2025 at 2:18 PM
More miR-awesomeness from @amandality.bsky.social and team in the @hfhs-bjc.bsky.social! Great diagnostic potential for miR's in both #Osteoarthritis and #RheumatoidArthritis.
Reposted by Amanda Ali
🚨🚨New publication alert! The Ali Lab @amandality.bsky.social in the @hfhs-bjc.bsky.social uses sequencing to profile microRNAs in early-stages of both osteoarthritis and rheumatoid arthritis! Now published in Scientific Reports @natureportfolio.nature.com, read it here: rdcu.be/eylic
Circulating microRNA profiles in early-stage osteoarthritis and rheumatoid arthritis
Scientific Reports - Circulating microRNA profiles in early-stage osteoarthritis and rheumatoid arthritis
rdcu.be
July 31, 2025 at 1:52 PM
🚨🚨New publication alert! The Ali Lab @amandality.bsky.social in the @hfhs-bjc.bsky.social uses sequencing to profile microRNAs in early-stages of both osteoarthritis and rheumatoid arthritis! Now published in Scientific Reports @natureportfolio.nature.com, read it here: rdcu.be/eylic
Reposted by Amanda Ali
The Henry Ford Health Bone & Joint Center has a storied history with microCT imaging of MSK tissues, thanks primarily to Dr. Yeni's group. Today we took a large leap forward with the installation of a brand new Scanco MicroCT-90 system! #orthopaedics #imaging #bone #cartilage
July 26, 2025 at 12:52 AM
The Henry Ford Health Bone & Joint Center has a storied history with microCT imaging of MSK tissues, thanks primarily to Dr. Yeni's group. Today we took a large leap forward with the installation of a brand new Scanco MicroCT-90 system! #orthopaedics #imaging #bone #cartilage
My gratitude to the Beier family for allowing us to join his celebration of life memorial. Frank will be deeply missed by the scientific community and will not be forgotten. I am so grateful for his mentorship in shaping my career in osteoarthritis research. We love you Frank. @beierlab.bsky.social
July 25, 2025 at 4:56 PM
My gratitude to the Beier family for allowing us to join his celebration of life memorial. Frank will be deeply missed by the scientific community and will not be forgotten. I am so grateful for his mentorship in shaping my career in osteoarthritis research. We love you Frank. @beierlab.bsky.social
Reposted by Amanda Ali
In his memory, Western has opened an equity-based graduate scholarship. Please consider supporting his final initiative if you are able: www.westernconnect.ca/beier ; thank you for all the time you spent and laughs you shared with him. We love and miss him so much already. - The Beiers
July 24, 2025 at 3:09 PM
In his memory, Western has opened an equity-based graduate scholarship. Please consider supporting his final initiative if you are able: www.westernconnect.ca/beier ; thank you for all the time you spent and laughs you shared with him. We love and miss him so much already. - The Beiers
Reposted by Amanda Ali
Thank you, @beierlab.bsky.social , for your remarkable impact you will be deeply missed
❤️ The Frank Beier Graduate Opportunity Scholarship is one way your legacy of generosity and mentorship will live on. I miss you!
www.giving.westernu.ca/giving/frank...
❤️ The Frank Beier Graduate Opportunity Scholarship is one way your legacy of generosity and mentorship will live on. I miss you!
www.giving.westernu.ca/giving/frank...
The Frank Beier Graduate Opportunity Scholarship
www.giving.westernu.ca
July 23, 2025 at 8:52 AM
Thank you, @beierlab.bsky.social , for your remarkable impact you will be deeply missed
❤️ The Frank Beier Graduate Opportunity Scholarship is one way your legacy of generosity and mentorship will live on. I miss you!
www.giving.westernu.ca/giving/frank...
❤️ The Frank Beier Graduate Opportunity Scholarship is one way your legacy of generosity and mentorship will live on. I miss you!
www.giving.westernu.ca/giving/frank...
Nothing. Nothing. Something.
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Wordle 1,492 3/6
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July 21, 2025 at 3:43 AM
Nothing. Nothing. Something.
Wordle 1,492 3/6
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Reposted by Amanda Ali
ICYMI: New content online:
Synovial fluid as a complex molecular pool contributing to knee osteoarthritis
Nature Reviews Rheumatology, Published online: 07 July 2025; doi:10.1038/s41584-025-01271-4The synovial fluid lubricates joints while also collecting molecular mediators from surrounding tissues. This Review highlights how molecular analyses of the synovial fluid might provide information on the progression of knee osteoarthritis and treatment efficacy, and identify potential therapeutic strategies targeting synovial fluid mediators in knee osteoarthritis.
bit.ly
July 12, 2025 at 11:32 AM
ICYMI: New content online:
Appreciate the feature of our recent publication in @natcomms.nature.com, thank you @henryfordhealth.bsky.social Ortho in Motion! www.henryford.com/-/media/file...
July 15, 2025 at 2:24 PM
Appreciate the feature of our recent publication in @natcomms.nature.com, thank you @henryfordhealth.bsky.social Ortho in Motion! www.henryford.com/-/media/file...