Joel Boerckel
@jboerckel.bsky.social
Assc Prof @pennmedicine.bsky.social.
Co-Director, McKay Orthopaedic Research Labs.
Mechanobiology of development & regeneration.
Prov. 25:2. 🦛
Philadelphia, PA
Co-Director, McKay Orthopaedic Research Labs.
Mechanobiology of development & regeneration.
Prov. 25:2. 🦛
Philadelphia, PA
Pinned
Joel Boerckel
@jboerckel.bsky.social
· Jun 19
Out latest preprint, from @cpane94.bsky.social in the lab, is out today!
Maternal exercise rescues fetal akinesia-impaired joint and bone development.
www.biorxiv.org/content/10.1...
So excited for this one - a wonderful collab with Niamh Nowlan, supported by the US-Ireland Partnership Programme ❤️
Maternal exercise rescues fetal akinesia-impaired joint and bone development.
www.biorxiv.org/content/10.1...
So excited for this one - a wonderful collab with Niamh Nowlan, supported by the US-Ireland Partnership Programme ❤️
Very excited to see our paper, led by @amilangscience.bsky.social, out today in @pnas.org!
This one was a true adventure, filled with surprises at every turn.
“Erythroid precursors regulate local oxygen tension and repair outcomes in the bone marrow niche.”
www.pnas.org/eprint/NJ8XC...
This one was a true adventure, filled with surprises at every turn.
“Erythroid precursors regulate local oxygen tension and repair outcomes in the bone marrow niche.”
www.pnas.org/eprint/NJ8XC...
Erythroid precursors regulate local oxygen tension and repair outcomes in the bone marrow niche | PNAS
Oxygen tension dynamically regulates stem cell fate and tissue regeneration, yet how
local oxygen availability is controlled within the bone marrow...
www.pnas.org
November 13, 2025 at 4:45 AM
Very excited to see our paper, led by @amilangscience.bsky.social, out today in @pnas.org!
This one was a true adventure, filled with surprises at every turn.
“Erythroid precursors regulate local oxygen tension and repair outcomes in the bone marrow niche.”
www.pnas.org/eprint/NJ8XC...
This one was a true adventure, filled with surprises at every turn.
“Erythroid precursors regulate local oxygen tension and repair outcomes in the bone marrow niche.”
www.pnas.org/eprint/NJ8XC...
My son is writing a report about viscous dampers and Newton’s Laws. He has asked for my help; I am in my glory.
October 21, 2025 at 1:56 AM
My son is writing a report about viscous dampers and Newton’s Laws. He has asked for my help; I am in my glory.
in college i did an engineering school study-abroad in paris. our assignment was to visit the louvre, decide what we would steal, and design a heist...
October 20, 2025 at 6:14 PM
in college i did an engineering school study-abroad in paris. our assignment was to visit the louvre, decide what we would steal, and design a heist...
Reposted by Joel Boerckel
I call it “joyful rigor” when I explain this effort to my students. I don’t believe in or rather, I’m not a “suffering poet.” I’m a writer who enjoys writing. The work works on me and I’m grateful for the opportunity to delve into the process at my own pace and to be changed by it.
That’s the other thing that baffles me about AI and creative writing, actually.
The work IS the joy for me. I don’t want to be able to snap my fingers and have a completed “product.” I want to be transformed by the process. I’m an author but I do this because I enjoy the rigor of being a writer.
The work IS the joy for me. I don’t want to be able to snap my fingers and have a completed “product.” I want to be transformed by the process. I’m an author but I do this because I enjoy the rigor of being a writer.
In terms of process, I enjoy writing but revising????? Oh, that’s my real kink. A second or third draft???? A fourth???? Making tweaks on my desktop AND my phone???? *moans* I’m a WHORE for revision.
October 20, 2025 at 3:09 PM
I call it “joyful rigor” when I explain this effort to my students. I don’t believe in or rather, I’m not a “suffering poet.” I’m a writer who enjoys writing. The work works on me and I’m grateful for the opportunity to delve into the process at my own pace and to be changed by it.
Reposted by Joel Boerckel
HUGE congratulations to Aboubacar Wague for 🏆 winning the ISFR 3-MT Research Pitch Competition today! Aboubacar presented his work on the anti-bacterial properties of Fibro-Adipogenic Progenitors in infection control during fracture repair! 🦴🦠🔬 #bonehealing
June 26, 2025 at 4:13 AM
HUGE congratulations to Aboubacar Wague for 🏆 winning the ISFR 3-MT Research Pitch Competition today! Aboubacar presented his work on the anti-bacterial properties of Fibro-Adipogenic Progenitors in infection control during fracture repair! 🦴🦠🔬 #bonehealing
Out latest preprint, from @cpane94.bsky.social in the lab, is out today!
Maternal exercise rescues fetal akinesia-impaired joint and bone development.
www.biorxiv.org/content/10.1...
So excited for this one - a wonderful collab with Niamh Nowlan, supported by the US-Ireland Partnership Programme ❤️
Maternal exercise rescues fetal akinesia-impaired joint and bone development.
www.biorxiv.org/content/10.1...
So excited for this one - a wonderful collab with Niamh Nowlan, supported by the US-Ireland Partnership Programme ❤️
June 19, 2025 at 1:01 AM
Out latest preprint, from @cpane94.bsky.social in the lab, is out today!
Maternal exercise rescues fetal akinesia-impaired joint and bone development.
www.biorxiv.org/content/10.1...
So excited for this one - a wonderful collab with Niamh Nowlan, supported by the US-Ireland Partnership Programme ❤️
Maternal exercise rescues fetal akinesia-impaired joint and bone development.
www.biorxiv.org/content/10.1...
So excited for this one - a wonderful collab with Niamh Nowlan, supported by the US-Ireland Partnership Programme ❤️
Reposted by Joel Boerckel
Such a pleasure to contribute to this nice session 🧫🦴🔬 thanks for the shout out @ricgottardi.bsky.social so glad for your contribution to the project I just highlighted. Looking forward to amazing days in #Davos at #eors2025 🩻🎉
Go @amilangscience.bsky.social! Great talk at #eors2025 from in vitro models to in vivo and back in vitro to study fracture healing and the role of vasculature! @umich.edu @jboerckel.bsky.social
June 16, 2025 at 9:39 AM
Such a pleasure to contribute to this nice session 🧫🦴🔬 thanks for the shout out @ricgottardi.bsky.social so glad for your contribution to the project I just highlighted. Looking forward to amazing days in #Davos at #eors2025 🩻🎉
Reposted by Joel Boerckel
Today @asbmr.bsky.social celebrates another superstar in the MSK field! @gkotsaris90.bsky.social at UPenn focuses on how mechanical cues influence the immune landscape during tissue regeneration ! Check out his bibliography and follow him to keep up with his work #ASBMR #memberspotlight 🔬
June 12, 2025 at 6:43 PM
Today @asbmr.bsky.social celebrates another superstar in the MSK field! @gkotsaris90.bsky.social at UPenn focuses on how mechanical cues influence the immune landscape during tissue regeneration ! Check out his bibliography and follow him to keep up with his work #ASBMR #memberspotlight 🔬
Such a bittersweet day in the lab - so proud of you @madhura0327.bsky.social! 🙌🏻
I’m so excited to see everything you’ll discover next with @cjrosenlab.bsky.social!
I’m so excited to see everything you’ll discover next with @cjrosenlab.bsky.social!
Wrapping up my last day in @jboerckel.bsky.social’s lab with one last round of imaging with @gkotsaris90.bsky.social! Philly’s been home for six incredible years—full of science, laughter, and amazing friends. It’s a tough world, but the besties make it less scary. On to the next adventure ❤️
June 14, 2025 at 12:13 PM
Such a bittersweet day in the lab - so proud of you @madhura0327.bsky.social! 🙌🏻
I’m so excited to see everything you’ll discover next with @cjrosenlab.bsky.social!
I’m so excited to see everything you’ll discover next with @cjrosenlab.bsky.social!
Proud to see @cpane94.bsky.social giving an @asbmr.bsky.social Member Spotlight Webinar next week (Thursday the 12th)!
He'll be talking about his latest work: "Maternal exercise rescues fetal akinesia-impaired joint and bone development"
Register here: d5jjrf04.na1.hubspotlinks.com/Ctc/5I+113/d...
He'll be talking about his latest work: "Maternal exercise rescues fetal akinesia-impaired joint and bone development"
Register here: d5jjrf04.na1.hubspotlinks.com/Ctc/5I+113/d...
June 4, 2025 at 2:35 PM
Proud to see @cpane94.bsky.social giving an @asbmr.bsky.social Member Spotlight Webinar next week (Thursday the 12th)!
He'll be talking about his latest work: "Maternal exercise rescues fetal akinesia-impaired joint and bone development"
Register here: d5jjrf04.na1.hubspotlinks.com/Ctc/5I+113/d...
He'll be talking about his latest work: "Maternal exercise rescues fetal akinesia-impaired joint and bone development"
Register here: d5jjrf04.na1.hubspotlinks.com/Ctc/5I+113/d...
Reposted by Joel Boerckel
Honoured to receive the Lifetime Achievement Award from the Canadian Connective Tissue Society! A testament to the great work by our fantastic lab members and collaborators over the last 25 years or so. Thank you all!!
Scientific Program
The 29th Annual Canadian Connective Tissue ConferenceMontreal, QC, May 26-28, 2025 Overview Download the complete program booklet: CCTC 2025 Program Booklet DATE / TIME EVENT DETAILS DAY 1 Monday, May...
connective-tissue-canada.com
May 29, 2025 at 6:58 PM
Honoured to receive the Lifetime Achievement Award from the Canadian Connective Tissue Society! A testament to the great work by our fantastic lab members and collaborators over the last 25 years or so. Thank you all!!
Congrats @clarissacoveney.bsky.social & @tdcapellini.bsky.social!
1) Despite the chaos, I am very pleased to present the terrific research conducted by my post-doc @clarissacoveney.bsky.social. acrjournals.onlinelibrary.wiley.com/doi/10.1002/...
Complex regulatory interactions at GDF5 shape joint morphology and osteoarthritis disease risk
Objectives To reveal causal level osteoarthritis (OA) disease biology by targeting regulatory interactions at GDF5. Methods By investigating different GDF5 regulatory regions (R2, R3-5, R7-R9, R18...
acrjournals.onlinelibrary.wiley.com
May 28, 2025 at 10:53 AM
Congrats @clarissacoveney.bsky.social & @tdcapellini.bsky.social!
Reposted by Joel Boerckel
One problem we face today is how few people understand the science that helps us all. Some scientists are able to explain the importance of their work. @baym.lol of Harvard University is one of them. Science is for everyone, and benefits us all more than most people know.
May 24, 2025 at 11:31 PM
One problem we face today is how few people understand the science that helps us all. Some scientists are able to explain the importance of their work. @baym.lol of Harvard University is one of them. Science is for everyone, and benefits us all more than most people know.
Eadweard in the wild @cpane94.bsky.social
Eadweard Muybridge did this cat motion study in 1887. Just posting it for everyone who thinks Edwardian and late Victorian cats had to sit still for 5 minutes to be photographed. ☺️ www.musee-orsay.fr/fr/oeuvres/c...
May 24, 2025 at 12:59 PM
Eadweard in the wild @cpane94.bsky.social
Reposted by Joel Boerckel
Alcian blue staining of cartilage in a two-headed zebrafish embryo. Credit to @jakeleyhr.bsky.social. #ZebrafishZunday 🧪
May 18, 2025 at 2:33 PM
Alcian blue staining of cartilage in a two-headed zebrafish embryo. Credit to @jakeleyhr.bsky.social. #ZebrafishZunday 🧪
Helping Gracie with her school science project today.
I truly did not realize how impossible it is now to find actual sources of reliable information without knowing how to dig into the deep pages of the internet.
It’s all AI junk.
I truly did not realize how impossible it is now to find actual sources of reliable information without knowing how to dig into the deep pages of the internet.
It’s all AI junk.
May 18, 2025 at 4:10 PM
Helping Gracie with her school science project today.
I truly did not realize how impossible it is now to find actual sources of reliable information without knowing how to dig into the deep pages of the internet.
It’s all AI junk.
I truly did not realize how impossible it is now to find actual sources of reliable information without knowing how to dig into the deep pages of the internet.
It’s all AI junk.
This short WBUR interview with my dear friend Michael @baym.lol - about the govt’s cuts to his lab at Harvard is excellent. He so clearly articulates what’s at risk.
www.wbur.org/news/2025/05...
www.wbur.org/news/2025/05...
May 17, 2025 at 1:36 AM
This short WBUR interview with my dear friend Michael @baym.lol - about the govt’s cuts to his lab at Harvard is excellent. He so clearly articulates what’s at risk.
www.wbur.org/news/2025/05...
www.wbur.org/news/2025/05...
I’m in this joke.
PI: "this draft is so great, why didn't we write it this way in the first place??"
PhD student: "I did, and then you told me to change it"
PhD student: "I did, and then you told me to change it"
May 15, 2025 at 11:44 PM
I’m in this joke.
Our paper, led by Chris Panebianco (@cpane94.bsky.social) is out today at Developmental Dynamics!
"Dynamics of postnatal bone development and epiphyseal synostosis in the caprine autopod."
anatomypubs.onlinelibrary.wiley.com/doi/10.1002/...
"Dynamics of postnatal bone development and epiphyseal synostosis in the caprine autopod."
anatomypubs.onlinelibrary.wiley.com/doi/10.1002/...
May 14, 2025 at 3:32 PM
Our paper, led by Chris Panebianco (@cpane94.bsky.social) is out today at Developmental Dynamics!
"Dynamics of postnatal bone development and epiphyseal synostosis in the caprine autopod."
anatomypubs.onlinelibrary.wiley.com/doi/10.1002/...
"Dynamics of postnatal bone development and epiphyseal synostosis in the caprine autopod."
anatomypubs.onlinelibrary.wiley.com/doi/10.1002/...
Our problem is not that our society does not sufficiently appreciate the economic return on investment in science. It is that we value education and knowledge generation only in economic terms.
May 7, 2025 at 9:57 PM
Our problem is not that our society does not sufficiently appreciate the economic return on investment in science. It is that we value education and knowledge generation only in economic terms.
Nothing calms like going to the library and bringing home a good poet.
May 6, 2025 at 6:39 PM
Nothing calms like going to the library and bringing home a good poet.
Me: *frowns at email
Monica: “Joel, what’s wrong?”
Me: “oh, just had a grant rejected.”
10yo: “AGAIN?”
13: “Does that mean we’re going broke?”
Monica: “Joel, what’s wrong?”
Me: “oh, just had a grant rejected.”
10yo: “AGAIN?”
13: “Does that mean we’re going broke?”
May 6, 2025 at 2:29 AM
Me: *frowns at email
Monica: “Joel, what’s wrong?”
Me: “oh, just had a grant rejected.”
10yo: “AGAIN?”
13: “Does that mean we’re going broke?”
Monica: “Joel, what’s wrong?”
Me: “oh, just had a grant rejected.”
10yo: “AGAIN?”
13: “Does that mean we’re going broke?”
Facilities, overhead.
May 3, 2025 at 5:54 PM
Facilities, overhead.
i wish we could go back to arguing over the merits of two-aim R01s on twitter again. turns out those were the days.
April 30, 2025 at 2:30 AM
i wish we could go back to arguing over the merits of two-aim R01s on twitter again. turns out those were the days.
The dignity of continuity had been taken away. Both past and future were disappearing from them, the past because nobody would remember it, the future because nobody could imagine it. What they knew was passing from the world. Before long it would not be known. They were the last of their kind.
-WB
-WB
April 27, 2025 at 6:15 PM
The dignity of continuity had been taken away. Both past and future were disappearing from them, the past because nobody would remember it, the future because nobody could imagine it. What they knew was passing from the world. Before long it would not be known. They were the last of their kind.
-WB
-WB