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Reposted by Andy Hogan

Daniel Drucker @danieljdrucker.bsky.social · Sep 3

Compelling metabolic benefits of semaglutide over 30 weeks in patients with schizophrenia Rxed with second-generation antipsychotic agents jamanetwork.com/journals/jam...

Semaglutide Treatment of Antipsychotic-Treated Patients With Schizophrenia, Prediabetes, and Obesity

This multicenter randomized clinical trial assesses the effect of once-weekly administration of the glucagon-like peptide-1 receptor agonist semaglutide in adults treated with second-generation antips...

jamanetwork.com

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Reposted by Andy Hogan

Waggoner Lab @labwaggoner.bsky.social · Aug 29

MAIT and other innate-like T cells integrate adaptive immune responses to modulate interval-dependent reactogenicity to mRNA vaccines
www.science.org/doi/10.1126/... @sciimmunology.bsky.social @aliamini419.bsky.social @thelucygarner.bsky.social @nprovine.bsky.social

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Reposted by Andy Hogan

Daniel Drucker @danieljdrucker.bsky.social · Aug 15

The new metabolic medicines #T2D #obesity and #inflammation www.cell.com/trends/endoc...

Repurposing metabolic drugs as anti-inflammatory agents

Dysregulation of bodyweight systemic metabolism is intrinsically linked to an inflammatory phenotype, with each underpinning the other. Over the past decade, new classes of drug, such as glucagon-like...

www.cell.com

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Andy Hogan @andyhogan82.bsky.social · Aug 13

Delighted to share our new review in @cp-trendsendomet.bsky.social on Repurposing metabolic drugs (GLP-1s & SGLT2s) as anti-inflammatory agents! Thanks to @nickjonesimmuno.bsky.social for this joint effort
doi.org/10.1016/j.te...

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Reposted by Andy Hogan

Karen English @karenenglish.bsky.social · Aug 7

Delighted to have our latest paper now online in Stem Cell Research & Therapy rdcu.be/ezDs3
Congrats to lead co-first authors @courteney.bsky.social @laurabitterlich.bsky.social and collaborators @james Ankrum @andyhogan82.bsky.social @maynoothuniversity.ie

Palmitate enhances MSC immunomodulation of human macrophages via the ceramide/CCL2 axis in vitro

rdcu.be

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Reposted by Andy Hogan

Lydia Lynch @lydialynch.bsky.social · Jul 28

This was a labor of love requiring lots of teamwork over years, repeating in 3 locations! Thanks to all the lab over the years, giving their time generously to this team project, & our wonderful collaborators. The source of fat matters for anti-tumor immunity 🐄🐖🧈🌴🫒🥥
www.nature.com/articles/s42...

The source of dietary fat influences anti-tumour immunity in obese mice - Nature Metabolism

This study shows that animal-based high-fat diets accelerate tumour growth and impair anti-tumour response to melanoma in obese mice, whereas plant-based high-fat diets do not.

www.nature.com

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Andy Hogan @andyhogan82.bsky.social · Jul 17

Excellent stuff Anna - congrats to all

Reposted by Andy Hogan

Discovery Immunology @discovimmunol.bsky.social · Jun 27

🦠 New research shows obesity disrupts dendritic cell responses to viruses by impairing cytokine production & metabolism - helping explain higher infection risk.

📖 Read the open-access study: https://bit.ly/40kBiiH

By @andrea-woodcock.bsky.social‬ et al.
##Immunology

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Andy Hogan @andyhogan82.bsky.social · Jun 5

Couple of months into our new social media experiment and we are blown away by the engagement - over 2.6 million views on TikTok alone and the daily feedback both online and in person has been so positive and supportive! A whole new way of spreading research based info

vm.tiktok.com/ZNdSrMT71/

TikTok - Make Your Day

vm.tiktok.com

Andy Hogan @andyhogan82.bsky.social · May 20

Our lab @obesityimmunology.bsky.social is looking to support a stellar scientist in their application to the Marie-Sklodowska-Curie European or Global Fellowship to join us to unravel the impact of obesity on the immune system - DM or email [email protected] for details europa.eu/!B8hjh3

Choose Europe: advance your research career in the EU

Move to the EU as a researcher or scientist. Discover how to relocate, find jobs and funding, and enjoy Europe's excellent quality of life.

europa.eu

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Andy Hogan @andyhogan82.bsky.social · May 13

Brilliant work Karen & co
Congrats!!

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Andy Hogan @andyhogan82.bsky.social · Apr 8

www.tiktok.com/@osheahoganl...

Is obesity a contagious disease 🤔 #research #sugar #obesity #obesityawarness #immunology #study #addiction

TikTok video by O’Shea Hogan Labs

www.tiktok.com

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Andy Hogan @andyhogan82.bsky.social · Mar 26

En route home from @kingscollegelondon.bsky.social after 2 days of fantastic science chats! Huge thanks to @peruchalab.bsky.social for the invite and hospitality. Hopefully lots of new collaborations

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Reposted by Andy Hogan

ICB - the journal @immunolcellbiol.bsky.social · Feb 20

Obesity is associated with increased susceptibility to infection, which may be due to obesity-induced immune dysregulation. The latest article exchange highlight from @discovimmunol.bsky.social looks at dendritic cell responses to Sendai Virus in a mouse model of diet-induced obesity.

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Reposted by Andy Hogan

Immunity @cp-immunity.bsky.social · Mar 14

Lactate: A key regulator of the immune response

Lactate shows immunomodulatory properties. Mauro et al. review how lactate serves a fuel for the TCA cycle and an immunomodulatory molecule with context-dependent effects, and how its immunomodulatory properties are mediated via sensing through…

dlvr.it

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Andy Hogan @andyhogan82.bsky.social · Mar 6

More evidence for GLP-1 medications in limiting rates of cancer. "The findings of this cohort study suggest that GLP-1RAs are associated with reduced risk of developing several hematologic cancers in patients with T2D"
jamanetwork.com/journals/jam...

Hematologic Cancers Among Patients With Type 2 Diabetes Prescribed GLP-1RAs

This cohort study compares the risks of developing different hematologic cancers in patients with type 2 diabetes treated with glucagon-like peptide–1 receptor agonists (GLP-1RAs) compared with metfor...

jamanetwork.com

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Andy Hogan @andyhogan82.bsky.social · Mar 3

At the Irish Coalition for People living with Obesity's (ICPO) book launch - a child friendly non-stigmatizing introduction to what is Obesity - great initiative

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Reposted by Andy Hogan

Alejandro Brenes @ajbrenes.com · Mar 2

For my immunology followers, the cantrell lab is on bluesky. Applied proteomics, immunometabolism, T cells, protein degradation, signalling what more could you ask for?

Give them a follow: @cantrell-lab.bsky.social

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Andy Hogan @andyhogan82.bsky.social · Feb 27

Very latest work from @lindavsinclair.bsky.social out today in Nature Immunology www.nature.com/articles/s41...

Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machinery in CD8 T cells - Nature Immunology

Sinclair et al. combine quantitative proteomics and an autophagy flux reporter to map autophagy substrates and triggers during CD8 T cell differentiation. Proteins degraded and fueled by autophagy in ...

www.nature.com

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Reposted by Andy Hogan

Daniel Drucker @danieljdrucker.bsky.social · Feb 25

Changes in body composition following tirzepatide treatment in a substudy of participants from the SURMOUNT-1 trial; the change in body weight, fat mass and lean mass from baseline to Week 72 was −21.3%, −33.9% and −10.9%, consistent across subgroups dom-pubs.onlinelibrary.wiley.com/doi/full/10....

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Andy Hogan @andyhogan82.bsky.social · Feb 7

🚨 new paper alert!!
Congrats to Andrea Woodcock on delivering this from during the depths of the pandemic! Thanks to @mary-canavan.bsky.social for the collab. Obesity drives dysregulation in DC responses to viral infection
academic.oup.com/discovimmuno...

Obesity drives dysregulation in DC responses to viral infection

AbstractIntroduction. Obesity is a worldwide epidemic, with over 1 billion people worldwide living with obesity. It is associated with an increased risk of

academic.oup.com

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Andy Hogan @andyhogan82.bsky.social · Feb 4

Great new paper from Sandberg group @ki.se in @pnas.org showing IL-10 producing MAIT cells - a population negatively regulated by IL-18

www.pnas.org/doi/10.1073/...

PNAS

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...

www.pnas.org

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Andy Hogan @andyhogan82.bsky.social · Jan 31

Brilliant presentation from @ArdenaBeirsha from our lab today at #IGCT25 conference @maynoothuni.bsky.social

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Andy Hogan @andyhogan82.bsky.social · Jan 29

Brilliant stuff April!

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Reposted by Andy Hogan

CD1-MR1 Immunology @cd1mr1.bsky.social · Jan 26

Our second webinar hosted from USA, will be by Laurent Gapin and Antonia Rotolo.
Thursday, February 6th at 16:00 GMT (8:00 Pacific, 11:00 Eastern, 1:00 Friday Tokyo)

If you haven't join, get updates and link here: www.cd1mr1.com/cd1-mr1-soci...

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