Andy Hogan
@andyhogan82.bsky.social
Immunologist interested in all things MAIT cells, Obesity, NK cells & Cancer. Professor at Maynooth University
My favourite meeting! Brilliant science and even better community!! Recommend for all from new PhD to old Profs
Don't miss out on your chance to attend "Fuelling the immune response IV: #UKimmunometabolismMeeting2026"
Those that have joined before will know these are fantastic meetings providing an open & productive forum to discuss really cool science
📆16-17th April
www.immunology.org/events/fuell...
Those that have joined before will know these are fantastic meetings providing an open & productive forum to discuss really cool science
📆16-17th April
www.immunology.org/events/fuell...
Fuelling the immune response IV: UK immunometabolism meeting 2026 | British Society for Immunology
www.immunology.org
January 6, 2026 at 8:17 PM
My favourite meeting! Brilliant science and even better community!! Recommend for all from new PhD to old Profs
Reposted by Andy Hogan
Registrations are now open for 'Fuelling the immune response', the 4th UK immunometabolism meeting, led by the BSI Immunometabolism Affinity Group.
Join us in Newcastle on 16 and 17 April 2026 for cutting edge immune metabolism research #UKimmunomet26
Register here: https://bit.ly/493uE45
Join us in Newcastle on 16 and 17 April 2026 for cutting edge immune metabolism research #UKimmunomet26
Register here: https://bit.ly/493uE45
December 18, 2025 at 9:25 AM
Registrations are now open for 'Fuelling the immune response', the 4th UK immunometabolism meeting, led by the BSI Immunometabolism Affinity Group.
Join us in Newcastle on 16 and 17 April 2026 for cutting edge immune metabolism research #UKimmunomet26
Register here: https://bit.ly/493uE45
Join us in Newcastle on 16 and 17 April 2026 for cutting edge immune metabolism research #UKimmunomet26
Register here: https://bit.ly/493uE45
Reposted by Andy Hogan
Seeking a junior scientist for scRNA-seq analytics in Cologne or remotely. If terms like Seurat, DimPlot, or ggplot2 spark recognition—or curiosity—you might be a fit.Flexible $$ Contract, Part time, MSc-to-PhD transition, or PhD project possible. Please feel free to reach out: [email protected]
November 20, 2025 at 7:09 PM
Seeking a junior scientist for scRNA-seq analytics in Cologne or remotely. If terms like Seurat, DimPlot, or ggplot2 spark recognition—or curiosity—you might be a fit.Flexible $$ Contract, Part time, MSc-to-PhD transition, or PhD project possible. Please feel free to reach out: [email protected]
Reposted by Andy Hogan
Studies of T cell acute lymphoblastic leukemia reveal that canagliflozin possesses potent anti-leukaemic effects underpinned by proliferative defects, cell cycle disruption and apoptosis, actions synergized by restriction of serine and glycine www.sciencedirect.com/science/arti...
Canagliflozin synergises with serine restriction mediating anti-leukaemic effects in T-cell acute lymphoblastic leukaemia
T-cell acute lymphoblastic leukaemia (T-ALL) is a haematological malignancy commonly driven by NOTCH1 activating mutations. A concomitant feature asso…
www.sciencedirect.com
October 20, 2025 at 7:40 PM
Studies of T cell acute lymphoblastic leukemia reveal that canagliflozin possesses potent anti-leukaemic effects underpinned by proliferative defects, cell cycle disruption and apoptosis, actions synergized by restriction of serine and glycine www.sciencedirect.com/science/arti...
Reposted by Andy Hogan
Compelling metabolic benefits of semaglutide over 30 weeks in patients with schizophrenia Rxed with second-generation antipsychotic agents jamanetwork.com/journals/jam...
Semaglutide Treatment of Antipsychotic-Treated Patients With Schizophrenia, Prediabetes, and Obesity
This multicenter randomized clinical trial assesses the effect of once-weekly administration of the glucagon-like peptide-1 receptor agonist semaglutide in adults treated with second-generation antips...
jamanetwork.com
September 3, 2025 at 9:18 PM
Compelling metabolic benefits of semaglutide over 30 weeks in patients with schizophrenia Rxed with second-generation antipsychotic agents jamanetwork.com/journals/jam...
Reposted by Andy Hogan
MAIT and other innate-like T cells integrate adaptive immune responses to modulate interval-dependent reactogenicity to mRNA vaccines
www.science.org/doi/10.1126/... @sciimmunology.bsky.social @aliamini419.bsky.social @thelucygarner.bsky.social @nprovine.bsky.social
www.science.org/doi/10.1126/... @sciimmunology.bsky.social @aliamini419.bsky.social @thelucygarner.bsky.social @nprovine.bsky.social
August 29, 2025 at 9:16 PM
MAIT and other innate-like T cells integrate adaptive immune responses to modulate interval-dependent reactogenicity to mRNA vaccines
www.science.org/doi/10.1126/... @sciimmunology.bsky.social @aliamini419.bsky.social @thelucygarner.bsky.social @nprovine.bsky.social
www.science.org/doi/10.1126/... @sciimmunology.bsky.social @aliamini419.bsky.social @thelucygarner.bsky.social @nprovine.bsky.social
Reposted by Andy Hogan
Delighted to share our new review in @cp-trendsendomet.bsky.social on Repurposing metabolic drugs (GLP-1s & SGLT2s) as anti-inflammatory agents! Thanks to @nickjonesimmuno.bsky.social for this joint effort
doi.org/10.1016/j.te...
doi.org/10.1016/j.te...
August 13, 2025 at 9:21 PM
Delighted to share our new review in @cp-trendsendomet.bsky.social on Repurposing metabolic drugs (GLP-1s & SGLT2s) as anti-inflammatory agents! Thanks to @nickjonesimmuno.bsky.social for this joint effort
doi.org/10.1016/j.te...
doi.org/10.1016/j.te...
Reposted by Andy Hogan
Delighted to have our latest paper now online in Stem Cell Research & Therapy rdcu.be/ezDs3
Congrats to lead co-first authors @courteney.bsky.social @laurabitterlich.bsky.social and collaborators @james Ankrum @andyhogan82.bsky.social @maynoothuniversity.ie
Congrats to lead co-first authors @courteney.bsky.social @laurabitterlich.bsky.social and collaborators @james Ankrum @andyhogan82.bsky.social @maynoothuniversity.ie
Palmitate enhances MSC immunomodulation of human macrophages via the ceramide/CCL2 axis in vitro
rdcu.be
August 7, 2025 at 4:43 AM
Delighted to have our latest paper now online in Stem Cell Research & Therapy rdcu.be/ezDs3
Congrats to lead co-first authors @courteney.bsky.social @laurabitterlich.bsky.social and collaborators @james Ankrum @andyhogan82.bsky.social @maynoothuniversity.ie
Congrats to lead co-first authors @courteney.bsky.social @laurabitterlich.bsky.social and collaborators @james Ankrum @andyhogan82.bsky.social @maynoothuniversity.ie
Reposted by Andy Hogan
This was a labor of love requiring lots of teamwork over years, repeating in 3 locations! Thanks to all the lab over the years, giving their time generously to this team project, & our wonderful collaborators. The source of fat matters for anti-tumor immunity 🐄🐖🧈🌴🫒🥥
www.nature.com/articles/s42...
www.nature.com/articles/s42...
The source of dietary fat influences anti-tumour immunity in obese mice - Nature Metabolism
This study shows that animal-based high-fat diets accelerate tumour growth and impair anti-tumour response to melanoma in obese mice, whereas plant-based high-fat diets do not.
www.nature.com
July 28, 2025 at 3:02 PM
This was a labor of love requiring lots of teamwork over years, repeating in 3 locations! Thanks to all the lab over the years, giving their time generously to this team project, & our wonderful collaborators. The source of fat matters for anti-tumor immunity 🐄🐖🧈🌴🫒🥥
www.nature.com/articles/s42...
www.nature.com/articles/s42...
Reposted by Andy Hogan
🦠 New research shows obesity disrupts dendritic cell responses to viruses by impairing cytokine production & metabolism - helping explain higher infection risk.
📖 Read the open-access study: https://bit.ly/40kBiiH
By @andrea-woodcock.bsky.social et al.
##Immunology
📖 Read the open-access study: https://bit.ly/40kBiiH
By @andrea-woodcock.bsky.social et al.
##Immunology
June 27, 2025 at 10:09 AM
🦠 New research shows obesity disrupts dendritic cell responses to viruses by impairing cytokine production & metabolism - helping explain higher infection risk.
📖 Read the open-access study: https://bit.ly/40kBiiH
By @andrea-woodcock.bsky.social et al.
##Immunology
📖 Read the open-access study: https://bit.ly/40kBiiH
By @andrea-woodcock.bsky.social et al.
##Immunology
Couple of months into our new social media experiment and we are blown away by the engagement - over 2.6 million views on TikTok alone and the daily feedback both online and in person has been so positive and supportive! A whole new way of spreading research based info
vm.tiktok.com/ZNdSrMT71/
vm.tiktok.com/ZNdSrMT71/
TikTok - Make Your Day
vm.tiktok.com
June 5, 2025 at 8:36 PM
Couple of months into our new social media experiment and we are blown away by the engagement - over 2.6 million views on TikTok alone and the daily feedback both online and in person has been so positive and supportive! A whole new way of spreading research based info
vm.tiktok.com/ZNdSrMT71/
vm.tiktok.com/ZNdSrMT71/
Our lab @obesityimmunology.bsky.social is looking to support a stellar scientist in their application to the Marie-Sklodowska-Curie European or Global Fellowship to join us to unravel the impact of obesity on the immune system - DM or email [email protected] for details europa.eu/!B8hjh3
Choose Europe: advance your research career in the EU
Move to the EU as a researcher or scientist. Discover how to relocate, find jobs and funding, and enjoy Europe's excellent quality of life.
europa.eu
May 20, 2025 at 7:58 PM
Our lab @obesityimmunology.bsky.social is looking to support a stellar scientist in their application to the Marie-Sklodowska-Curie European or Global Fellowship to join us to unravel the impact of obesity on the immune system - DM or email [email protected] for details europa.eu/!B8hjh3
En route home from @kingscollegelondon.bsky.social after 2 days of fantastic science chats! Huge thanks to @peruchalab.bsky.social for the invite and hospitality. Hopefully lots of new collaborations
March 26, 2025 at 4:43 PM
En route home from @kingscollegelondon.bsky.social after 2 days of fantastic science chats! Huge thanks to @peruchalab.bsky.social for the invite and hospitality. Hopefully lots of new collaborations
Reposted by Andy Hogan
Obesity is associated with increased susceptibility to infection, which may be due to obesity-induced immune dysregulation. The latest article exchange highlight from @discovimmunol.bsky.social looks at dendritic cell responses to Sendai Virus in a mouse model of diet-induced obesity.
February 20, 2025 at 6:14 AM
Obesity is associated with increased susceptibility to infection, which may be due to obesity-induced immune dysregulation. The latest article exchange highlight from @discovimmunol.bsky.social looks at dendritic cell responses to Sendai Virus in a mouse model of diet-induced obesity.
Reposted by Andy Hogan
More evidence for GLP-1 medications in limiting rates of cancer. "The findings of this cohort study suggest that GLP-1RAs are associated with reduced risk of developing several hematologic cancers in patients with T2D"
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
Hematologic Cancers Among Patients With Type 2 Diabetes Prescribed GLP-1RAs
This cohort study compares the risks of developing different hematologic cancers in patients with type 2 diabetes treated with glucagon-like peptide–1 receptor agonists (GLP-1RAs) compared with metfor...
jamanetwork.com
March 6, 2025 at 8:00 PM
More evidence for GLP-1 medications in limiting rates of cancer. "The findings of this cohort study suggest that GLP-1RAs are associated with reduced risk of developing several hematologic cancers in patients with T2D"
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
At the Irish Coalition for People living with Obesity's (ICPO) book launch - a child friendly non-stigmatizing introduction to what is Obesity - great initiative
March 3, 2025 at 7:45 PM
At the Irish Coalition for People living with Obesity's (ICPO) book launch - a child friendly non-stigmatizing introduction to what is Obesity - great initiative
Reposted by Andy Hogan
For my immunology followers, the cantrell lab is on bluesky. Applied proteomics, immunometabolism, T cells, protein degradation, signalling what more could you ask for?
Give them a follow: @cantrell-lab.bsky.social
Give them a follow: @cantrell-lab.bsky.social
March 2, 2025 at 7:29 PM
For my immunology followers, the cantrell lab is on bluesky. Applied proteomics, immunometabolism, T cells, protein degradation, signalling what more could you ask for?
Give them a follow: @cantrell-lab.bsky.social
Give them a follow: @cantrell-lab.bsky.social
Very latest work from @lindavsinclair.bsky.social out today in Nature Immunology www.nature.com/articles/s41...
Autophagy repression by antigen and cytokines shapes mitochondrial, migration and effector machinery in CD8 T cells - Nature Immunology
Sinclair et al. combine quantitative proteomics and an autophagy flux reporter to map autophagy substrates and triggers during CD8 T cell differentiation. Proteins degraded and fueled by autophagy in ...
www.nature.com
February 27, 2025 at 4:46 PM
Very latest work from @lindavsinclair.bsky.social out today in Nature Immunology www.nature.com/articles/s41...
Reposted by Andy Hogan
Changes in body composition following tirzepatide treatment in a substudy of participants from the SURMOUNT-1 trial; the change in body weight, fat mass and lean mass from baseline to Week 72 was −21.3%, −33.9% and −10.9%, consistent across subgroups dom-pubs.onlinelibrary.wiley.com/doi/full/10....
February 25, 2025 at 8:48 PM
Changes in body composition following tirzepatide treatment in a substudy of participants from the SURMOUNT-1 trial; the change in body weight, fat mass and lean mass from baseline to Week 72 was −21.3%, −33.9% and −10.9%, consistent across subgroups dom-pubs.onlinelibrary.wiley.com/doi/full/10....
🚨 new paper alert!!
Congrats to Andrea Woodcock on delivering this from during the depths of the pandemic! Thanks to @mary-canavan.bsky.social for the collab. Obesity drives dysregulation in DC responses to viral infection
academic.oup.com/discovimmuno...
Congrats to Andrea Woodcock on delivering this from during the depths of the pandemic! Thanks to @mary-canavan.bsky.social for the collab. Obesity drives dysregulation in DC responses to viral infection
academic.oup.com/discovimmuno...
Obesity drives dysregulation in DC responses to viral infection
AbstractIntroduction. Obesity is a worldwide epidemic, with over 1 billion people worldwide living with obesity. It is associated with an increased risk of
academic.oup.com
February 7, 2025 at 8:58 PM
🚨 new paper alert!!
Congrats to Andrea Woodcock on delivering this from during the depths of the pandemic! Thanks to @mary-canavan.bsky.social for the collab. Obesity drives dysregulation in DC responses to viral infection
academic.oup.com/discovimmuno...
Congrats to Andrea Woodcock on delivering this from during the depths of the pandemic! Thanks to @mary-canavan.bsky.social for the collab. Obesity drives dysregulation in DC responses to viral infection
academic.oup.com/discovimmuno...
Great new paper from Sandberg group @ki.se in @pnas.org showing IL-10 producing MAIT cells - a population negatively regulated by IL-18
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
February 4, 2025 at 8:43 PM
Great new paper from Sandberg group @ki.se in @pnas.org showing IL-10 producing MAIT cells - a population negatively regulated by IL-18
www.pnas.org/doi/10.1073/...
www.pnas.org/doi/10.1073/...
Brilliant presentation from @ArdenaBeirsha from our lab today at #IGCT25 conference @maynoothuni.bsky.social
January 31, 2025 at 10:13 AM
Brilliant presentation from @ArdenaBeirsha from our lab today at #IGCT25 conference @maynoothuni.bsky.social