Lightnews — Scholar-powered news

Alicia Cutler @anothercutler.bsky.social · 7d

We had a great time at #BMES2025. This was the first conference my lab attended together and I couldn't be more thrilled with their performance and the exciting work that we saw presented!

Reposted by Alicia Cutler

Nature Portfolio @natureportfolio.nature.com · Aug 24

A paper in Nature reports whole-genome sequences for 490,640 participants from the UK Biobank and combines these data with phenotypic data to provide new insights into the relationship between human variation and sequence variation. go.nature.com/415CMhr 🧬 🧪

This is figure 1, which shows the variant call sets.

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Reposted by Alicia Cutler

John Lindner @johnmlindner.bsky.social · Jul 7

Only two weeks left to apply for #ResearchFunding and join us in Ridgefield, Connecticut. Establish your own group and receive 890k USD/year for up to 5 years, access cutting-edge infrastructure!

career.bmedx.com/call/2025-RD...

#ScienceWithImpact #Ophthalmology #TissueEngineering #Biotherapeutics

BioMed X Institute

BioMed X Application System

career.bmedx.com

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Reposted by Alicia Cutler

Alt National Park Service @altnps.bsky.social · Jun 21

The U.S. Senate is currently considering a budget reconciliation bill that quietly includes language that could devastate our public lands. It would:
- Make over 250 million acres of public land eligible for sale
- Mandate the sale of at least 2 million acres of Forest Service and BLM land

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Alicia Cutler @anothercutler.bsky.social · Jun 21

My institute posted a request for proposals to lead a group focused on occular research. It's a good opportunity for someone ready to transition to independence or someone looking for a postdoc with private funding. Added bonus: ou get to be my neighbor!

career.bio.mx/call/2025-RD...

BioMed X Institute

BioMed X Application System

career.bio.mx

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Reposted by Alicia Cutler

Fabrice Jean-Pierre @fabricejpierre.bsky.social · Apr 7

Tenure-track Faculty position just opened up in my department! If you want to be part of a dynamic group who is excited about science, apply. For more details, visit www.usherbrooke.ca/emplois/offr...

Please share in your networks! #microsky

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Reposted by Alicia Cutler

Craig A. Goodman @craigagoodman1.bsky.social · Mar 29

Muscle-specific Ryanodine receptor 1 properties underlie limb-girdle muscular dystrophy 2B/R2 progression
www.nature.com/articles/s41...

Muscle-specific Ryanodine receptor 1 properties underlie limb-girdle muscular dystrophy 2B/R2 progression - Nature Communications

In this study by Meizoso-Huesca et al. regional skeletal muscle differences in ryanodine receptor Ca2+ leak were found. Without dysferlin, this raised leak is not tolerated long-term and leads to limb...

www.nature.com

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Reposted by Alicia Cutler

Mark Cuban @mcuban.bsky.social · Mar 22

From 2010 to 2016 (latest data I have ), NIH research contributed to EVERY drug approved by the FDA

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Alicia Cutler @anothercutler.bsky.social · Mar 19

@gabriellekardon.bsky.social is a fantastic scientist working on exciting projects. If you want to work on molecular biology in skeletal muscle, this could be your lucky day!

gabriellekardon.bsky.social @gabriellekardon.bsky.social · Mar 19

Looking to conduct research in molecular biology and genetics? Come join the Kardon lab! Looking for lab tech to help research the role of stem cells in muscle development and regeneration and determine the effects of viral infection on muscle. Funding independent of federal resources. Please share!

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Reposted by Alicia Cutler

Sherry Pagoto, PhD @drsherrypagoto.bsky.social · Mar 12

New report shows that NIH grants fueled $95 billion in economic activity and 407,782 jobs in 2024.

That's not to mention the countless lives that biomedical research has saved.

Show me a better investment than that.
www.forbes.com/sites/michae...

NIH Grants Fueled $95 Billion In FY 2024 Economic Activity, Finds New Report

National Institutes of Health grants generated almost $95 billion in economic activity nationwide in FY 2024 according to a new report by United for Medical Research.

www.forbes.com

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Reposted by Alicia Cutler

Dylan Burnette @mag2art.bsky.social · Mar 10

A heart muscle cell (cardiac myocyte) photographed through a microscope. Actin filaments are shown. #CellBiology

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Alicia Cutler @anothercutler.bsky.social · Mar 11

My lab is hiring a research assistant. If you love culturing cells but wish they weren't so flat, come bioprint with us: we culture in spheres! We culture in cubes! We culture in bioprinted vessels!
www.linkedin.com/jobs/view/41...

BioMed X Institute hiring Research Assistant - Complex Human Ex Vivo Models of Tissue Inflammation in New Haven, CT | LinkedIn

Posted 4:57:18 PM. About BioMed XBioMed X is an independent research institute with sites in Heidelberg, Germany, New…See this and similar jobs on LinkedIn.

www.linkedin.com

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Alicia Cutler @anothercutler.bsky.social · Mar 7

Skeletal muscle fibers have many nuclei and the nuclei are different from each other despite being inside the same cell. This excellent paper looks at specialized transcript profiles of the nuclei that maintain the neuromuscular junction. It's open access!

www.nature.com/articles/s41...

Single-nuclei sequencing of skeletal muscle reveals subsynaptic-specific transcripts involved in neuromuscular junction maintenance - Nature Communications

Here they use single nuclei RNA-seq to identify transcripts in skeletal muscle that maintain the neuromuscular junction, both under normal and denervated conditions, which allows them to characterize ...

www.nature.com

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Alicia Cutler @anothercutler.bsky.social · Mar 5

The long running effort to de-extinct wooly mammoths has given us the gift of wooly mice! By modifying 10 genes to match mammoth variants they made very cute very fluffy mice. Check out their preprint!

www.biorxiv.org/content/10.1...

www.biorxiv.org

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Alicia Cutler @anothercutler.bsky.social · Mar 2

Standing up for what is right comes with a personal cost, but gives us the world we want to live in. I am grateful for those who choose to do so across business, science, and government and hope that each of us can find the moral fiber to make similar choices when our time comes.

Nature Portfolio @natureportfolio.nature.com · Feb 28

Erika Cheung spoke with Nature about working at Theranos and how blowing the whistle on the company and Elizabeth Holmes changed her career. “I’m still in shock how much this derailed my life.” 🧪

How blowing the whistle on the Theranos scandal transformed Erika Cheung’s career

Cheung, a laboratory assistant straight from university, raised the alarm over dodgy science and a duplicitous boss.

go.nature.com

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Alicia Cutler @anothercutler.bsky.social · Feb 26

Thanks, John! My lab is building an in vitro artery to model inflammation. We can bioprint an artery with primary human cells and are excited to start seeing how it responds to inflammatory insult. Come perturb arteries with me in New Haven!

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Alicia Cutler @anothercutler.bsky.social · Feb 26

My lab is hiring! I have budget for a post-doc and a research assistant. We're bioprinting a 3D in vitro artery to model inflammation. If you wish you were bioprinting arteries with me in New Haven, CT, reach out! I'd be particularly excited if you have immunology experience!

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Reposted by Alicia Cutler

Nature Portfolio @natureportfolio.nature.com · Jan 29

A muscle patch developed using stem cells can help to repair failing hearts without adverse effects, according to a paper in Nature. #Medsky 🧪

Engineered heart muscle allografts for heart repair in primates and humans - Nature

Epicardial engineered heart muscle allografts from induced pluripotent stem cell-derived cardiomyocytes can safely and effectively remuscularize chronically failing hearts in rhesus macaques, leading to improved cardiac function and paving the way for human clinical trials.

go.nature.com

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Reposted by Alicia Cutler

Anita Corbett @acorbe2.bsky.social · Jan 23

Stop the halt of NIH!
I am reaching out to ask that you call your US Senators/Reps. Especially those of you in red states! Tell them how important the NIH is!

House of representatives switchboard: 202-224-3121

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Reposted by Alicia Cutler

Randall Munroe @xkcd.com · Jan 24

T. Rex Evolution xkcd.com/3042

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Reposted by Alicia Cutler

Golden Apple Foundation of New Mexico @gafnm.bsky.social · Jan 15

The White House honored five exceptional NM educators with the Presidential Award for Excellence in Math & Science Teaching. Congrats to Tara Palomares, Kimberly Conell, Heather Harrell, and Golden Apple Fellows Chris Speck (2018), and Lesha Rupert (2020)! 🎉

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Alicia Cutler @anothercutler.bsky.social · Jan 19

This paper came out of the Rossi lab. You will probably like it if you like: 1) fibroblast subtypes 2) T cell maturation 3) all the sequencing (CITE, ATAC, spatial) and 4) understudied sexually dimorphic traits.
www.cell.com/developmenta...

Sex-biased human thymic architecture guides T cell development through spatially defined niches

Stankiewicz et al. generate a spatial multiomic resource of human postnatal thymus. Using a niche-centric approach, they show that sex-based differences in thymus biology and T cell development arise ...

www.cell.com

Alicia Cutler @anothercutler.bsky.social · Jan 19

My institute has an open call for applications for a new oncology related project. I started my research group off a similar call and it has been a very exciting year and a half starting up the research!
Take a look!
career.bio.mx/call/2025-BM...

BioMed X Institute

BioMed X Application System

career.bio.mx

Alicia Cutler @anothercutler.bsky.social · Dec 3

This story grew out of a surprising result to a different experiment. Excellent work, Amie Chang!
www.sciencedirect.com/science/arti...

Myofibers cultured in viscoelastic hydrogels reveal the effects of integrin-binding and mechanosensing on muscle satellite cells

Quiescent skeletal muscle satellite cells (SCs) located on myofibers activate in response to muscle injury to regenerate muscle; however, identifying …

www.sciencedirect.com

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