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John Lindner @johnmlindner.bsky.social · Jul 7

Only two weeks left to apply for #ResearchFunding and join us in Ridgefield, Connecticut. Establish your own group and receive 890k USD/year for up to 5 years, access cutting-edge infrastructure!

career.bmedx.com/call/2025-RD...

#ScienceWithImpact #Ophthalmology #TissueEngineering #Biotherapeutics

BioMed X Institute

BioMed X Application System

career.bmedx.com

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John Lindner @johnmlindner.bsky.social · Jun 11

Do you have expertise in one or more of the following areas? #Ophthalmology #organotypic models #TissueEngineering #proteinengineering

Just over one month left in our newly opened call for applications to a new research group in Ridgefield, Conn.!
career.bmedx.com/call/2025-RD...

#ResearchJobs

BioMed X Institute

BioMed X Application System

career.bmedx.com

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John Lindner @johnmlindner.bsky.social · May 22

Our latest call for applications is now open! Early-career researchers in the fields of biotherapeutic engineering, ocular models, and assay technology are invited to join our Ridgefield, Connecticut location as part of an exciting new team! career.bio.mx/call/2025-RD...

BioMed X Institute

BioMed X Application System

career.bio.mx

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John Lindner @johnmlindner.bsky.social · Mar 11

Blending my personal and professional lives a bit here, but this is a great short read (and cool "then vs. now" perspective) on a rising star in a related field:

Chemists amid coronavirus five years on: @grynova.bsky.social www.chemistryworld.com/opinion/chem...

Chemists amid coronavirus five years on: Anya Gryn’ova

A computational chemist has moved from being group leader at a German research institute to an associate computational chemistry prof in the UK

www.chemistryworld.com

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Reposted by John Lindner

Alicia Cutler @anothercutler.bsky.social · Mar 11

My lab is hiring a research assistant. If you love culturing cells but wish they weren't so flat, come bioprint with us: we culture in spheres! We culture in cubes! We culture in bioprinted vessels!
www.linkedin.com/jobs/view/41...

BioMed X Institute hiring Research Assistant - Complex Human Ex Vivo Models of Tissue Inflammation in New Haven, CT | LinkedIn

Posted 4:57:18 PM. About BioMed XBioMed X is an independent research institute with sites in Heidelberg, Germany, New…See this and similar jobs on LinkedIn.

www.linkedin.com

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John Lindner @johnmlindner.bsky.social · Mar 8

In the face of pushback against workplace inclusion and diversity practices by some in power, it is incumbent on responsible leaders everywhere to ensure true fairness, recognize talent, and support the careers particularly of those given an inherent societal disadvantage! #InternationalWomensDay

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Reposted by John Lindner

EFIS_Immunology @efis-immunology.bsky.social · Feb 28

EFIS mourns the passing of Fritz Melchers
www.efis.org/news/fritz-m...

We extend heartfelt condolences to Fritz Melchers' family, friends, colleagues and the immunology community around the world.

Photo credit: Jacqueline Hirscher

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John Lindner @johnmlindner.bsky.social · Feb 25

To any and all affected scientists @altnih4science.bsky.social (or other opportunity-seekers), we're hiring in New Haven! Postdoc and RA position, please reach out to me or PI @anothercutler.bsky.social if interested, immunology/macrophage experience ideal, please share with your networks #immunosky

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Reposted by John Lindner

Katia Faliti @katyely.bsky.social · Dec 28

Fantastic News & Views article Nature Portfolio by @michelalocci.bsky.social & @sapostolidis.bsky.social, highlighting our recent study on mRNA vaccines and SLE, its findings, and the key questions to address next!

rdcu.be/d4332

#immunosky #SLE #mRNA #Bcells 🦠 👩‍🔬 💉

SLE B cells take an extrafollicular detour after mRNA vaccination

Nature Immunology - Systemic lupus erythematosus (SLE) is an autoimmune disease with considerable clinical heterogeneity and diverse treatment options. A study now shows that heightened...

rdcu.be

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John Lindner @johnmlindner.bsky.social · Nov 30

Not my work but I wish it was… general advice is to avoid buzz phrases like “tour de force” but let’s make an exception here and compliments to the authors for the precision in the title! Thanks @anothercutler.bsky.social for the heads up www.cell.com/cell/fulltex...

Atlas of the plasma proteome in health and disease in 53,026 adults

A large-scale proteomics study involving 53,026 individuals maps 2,920 plasma proteins to 406 prevalent diseases, 660 incident diseases, and 986 health-related traits, identifying promising biomarkers...

www.cell.com

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John Lindner @johnmlindner.bsky.social · Nov 30

Thanks for adding me! Still new to the scientific social media game… any particular hashtags we are using for a TCR/BCR catch-all?

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John Lindner @johnmlindner.bsky.social · Nov 28

I’m biased of course but this is a detailed new mechanism for the direct action of IL-2 on antigen-experiencing B cells, driving early/extrafollicular antibody responses! Congrats to @katyely.bsky.social and all co-authors on a job diligently and well done! Glad I could help #immunosky #bcells

Katia Faliti @katyely.bsky.social · Nov 28

✨ Ever wondered why B cells are so fond of IL-2? Wonder no more! Our study is now published in Immunity @cellpress.bsky.social 🔍📑 A truly perfect Thanksgiving gift! 🧑‍🔬💉🔬https://authors.elsevier.com/c/1kAq43qNrUxuTR

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John Lindner @johnmlindner.bsky.social · Nov 22

🙋‍♂️ Is IL6R D358A also protective against fibrotic progression?

Gabriele Pollara @gpollara.bsky.social · Nov 21

🚨 Delighted to share our paper defining a new role for IL-6 in TB. 🚨

We used genetic variation to show *reduced* IL-6 signalling is causally associated with *lower* risk of TB.

Lead author @gushamilton.bsky.social

#TBSky #IDSky #ImmunoSky www.thelancet.com/journals/lan...
Thread 👇 (1/8)

Altered IL-6 signalling and risk of tuberculosis: a multi-ancestry mendelian randomisation study

Our findings propose a causal relationship between reduced IL-6 signalling and lower risk of tuberculosis, akin to the effect seen in other IL-6 mediated diseases. This study suggests that IL-6 antago...

www.thelancet.com

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John Lindner @johnmlindner.bsky.social · Nov 21

Super cool repository, free for (non-commercial) use and still… should never, ever, under any circumstances be used in a PowerPoint presentation

sound-effects.bbcrewind.co.uk/search?resul...

BBC Sound Effects

sound-effects.bbcrewind.co.uk

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John Lindner @johnmlindner.bsky.social · Nov 21

Check out JLABS jnjinnovation.com/jlabs

Life Science Incubators And Accelerators @ JLABS | JNJ Innovation

At JLABS, our no-strings-attached life science incubator and accelerators enable innovators to deliver healthcare solutions to patients worldwide.

jnjinnovation.com

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John Lindner @johnmlindner.bsky.social · Nov 20

Kids, drugs are bad, don’t do them… also, learn to play the cello… also, forget the first part of what I said… you know what, just google “cello goblin” youtu.be/ucWTdsxL25E?...

Ear to the Ground: Rushad Eggleston

YouTube video by Beehive Productions

youtu.be

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John Lindner @johnmlindner.bsky.social · Nov 20

I guess Stable Diffusion needs physics to understand which finger this biologist should be holding up 😋

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John Lindner @johnmlindner.bsky.social · Nov 20

Indeed a fascinating new look at intratumoral T cell subsets! Would be great to learn about TCR clonality of “Subset 3” and whether these cells are (pre-)enriched for tumor specificities! #immunosky

Roham Parsa @rohamparsa.bsky.social · Nov 19

I’m very fascinated about this study showing stem cell-like effector CD4 T cells that can become the classic T helper subsets. In tumors, Tregs suppress these cells, blocking Th1 seeding and anti-tumor effects! Jenkins lab also recently described a similar CD4 phenotype with different implications.

Differentiation fate of a stem-like CD4 T cell controls immunity to cancer - Nature

A population of tumour-specific PD1+TCF1+ CD4 T cells in tumour-draining lymph nodes is capable of self-renewal and differentiation into CD4 effector cells, thereby controlling CD8 T cell activity.

www.nature.com

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John Lindner @johnmlindner.bsky.social · Nov 19

Does that generalize to models that don’t involve physics in the first place? 🤔 Let’s compromise and agree that infusing (more) physics into representations is essentially improving the training quality

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John Lindner @johnmlindner.bsky.social · Nov 19

Agree 💯 and will add that the only substantial way to make those models better at this point is to increase the quality and quantity of training data, which for us only happens in the wet lab

Calin Plesa @calin.bsky.social · Nov 19

Every day a new foundation model drops, and as an experimentalist, I just skim the preprint and go back to my pipettes. Foundation model fatigue. The bar for adoption is high and requires experimental validation.

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Reposted by John Lindner

Jan Böttcher @jboettcherlab.bsky.social · Nov 18

next #globalimmuno talk is on this Wednesday, November 20th at 9am PST, noon EST, 5pm GMT by Dr. Padmanee Sharma.

Title: “Mechanisms of Response and Resistance to Immune Checkpoint Therapy”
LINK: ucsd.zoom.us/j/91053505061

Current schedule : www.globalimmunotalks.org/schedule

Welcome! You are invited to join a webinar: GLOBAL IMMUNOTALKS . After registering, you will receive a confirmation email about joining the webinar.

Virtual immunology seminar series 2024 Organizers: Miriam Merad, Kazuyo Moro, Bali Pulendran, Gabriel Rabinovich, Caetano Reis e Sousa, Asya Rolls and Dietmar Zehn Q&A via X (former Twitter) @glob...

ucsd.zoom.us

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John Lindner @johnmlindner.bsky.social · Nov 19

We leverage synbio techniques to explore lymphocyte receptor:ligand interactions and build functional discovery reporters, would be grateful to be added to the pack!

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John Lindner @johnmlindner.bsky.social · Nov 19

🙋‍♂️

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John Lindner @johnmlindner.bsky.social · Nov 18

A little more than a week left to apply, for more information feel free to get in touch! And please forward to any friends and colleagues looking for a New England position in a unique academia/industry hybrid research center

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Reposted by John Lindner

Altmetric @altmetric.com · Nov 18

We strongly suggest that academic publishers and other platforms that host research rapidly implement a Share to Bluesky button for their articles. Here's how:

docs.bsky.app/docs/advance...

#AcademicSky #HigherEd #Altmetrics

Action Intent Links | Bluesky

Authors, websites, and apps can use action intent links to implement "Share on Bluesky" buttons, or similar in-app actions. Logged-in users will be directed to the corresponding action view in the Blu...

docs.bsky.app

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