Sebastian S. Cocioba
@atinygreencell.bsky.social
Flower Designer at Neoplants 🌺
Researcher at Binomica Labs
Degreeless Heathen
Petunia and Snapdragon Breeder
Open Lab Notebook: http://tinyurl.com/ATGCFFE
Researcher at Binomica Labs
Degreeless Heathen
Petunia and Snapdragon Breeder
Open Lab Notebook: http://tinyurl.com/ATGCFFE
Pinned
Sebastian's Biotech Bazaar
Designer of fine, hand-crafted, bespoke, and fully open source biotechnology tools for educators and researchers. Plasmids, lab equipment, cell lines, and seeds. An ever-growing collection of high qua...
ATinyGreenCell.com
Excited to announce some new plasmid offerings in my shop at atinygreencell.com! Here's a thread of the current catalog. All proceeds directly support my lab and my continued effort to build useful open-source tools. Feel free to get in touch if you want to know more. Please share! 💚
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Reposted by Sebastian S. Cocioba
Arabidopsis can be engineerded to smell as a rose! @nickdesnoyer.bsky.social and @atinygreencell.bsky.social that means we can also make it smell as a #Petunia!! #MetabolicEngineering #plantscience
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
Model-guided metabolic engineering of 2-phenylethanol in Arabidopsis
2-Phenylethanol (2-PE) is a natural aromatic compound with properties that make it a potential biological oxygenate for petroleum-derived gasoline. In…
www.sciencedirect.com
November 25, 2025 at 2:06 PM
Arabidopsis can be engineerded to smell as a rose! @nickdesnoyer.bsky.social and @atinygreencell.bsky.social that means we can also make it smell as a #Petunia!! #MetabolicEngineering #plantscience
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
The Ag ppl on LinkedIn are strangely helpful and kind. Between the endless bots and fake persona of that hellsite are islands of sincerity. Not sure how I feel about that now, lol.
November 24, 2025 at 12:54 PM
The Ag ppl on LinkedIn are strangely helpful and kind. Between the endless bots and fake persona of that hellsite are islands of sincerity. Not sure how I feel about that now, lol.
Reposted by Sebastian S. Cocioba
This kind of stuff is why I say that I worry that the tools of neuroscience are not properly vetted
“Our findings challenge the conventional focus on low-dimensional coding subspaces as a sufficient framework for understanding neural computations, demonstrating that dimensions previously considered task-irrelevant and accounting for little variance can have a critical role in driving behavior.”
Neural dynamics outside task-coding dimensions drive decision trajectories through transient amplification
Most behaviors involve neural dynamics in high-dimensional activity spaces. A common approach is to extract dimensions that capture task-related variability, such as those separating stimuli or choice...
www.biorxiv.org
November 23, 2025 at 3:02 PM
This kind of stuff is why I say that I worry that the tools of neuroscience are not properly vetted
Reposted by Sebastian S. Cocioba
🌶️🌶️🌶️
A gel-based artificial tongue can determine the spiciness of a wide range of foods
go.nature.com/4oafMqh
go.nature.com/4oafMqh
Synthetic tongue rates chillies’ heat — and spares human tasters
Gel-based device inspired by the cooling powers of milk assesses peppers whose burn ranges from mild to dangerous.
go.nature.com
November 24, 2025 at 12:41 PM
🌶️🌶️🌶️
Reposted by Sebastian S. Cocioba
Reposted by Sebastian S. Cocioba
Im a sucker for the copy on the RL website
November 23, 2025 at 3:33 PM
Im a sucker for the copy on the RL website
Behold, feeshpeepolmeeting. 🐟🧬🤝
Come join us in Heidelberg for the first German fish meeting 👩🔬👨🔬🧬🔬🐟🐠
November 23, 2025 at 5:10 AM
Behold, feeshpeepolmeeting. 🐟🧬🤝
Reposted by Sebastian S. Cocioba
Come join us in Heidelberg for the first German fish meeting 👩🔬👨🔬🧬🔬🐟🐠
November 22, 2025 at 6:08 PM
This very late bloomer is SO DARK. Here is a more typical bloom for comparison. Note the stark change in saturation between the corolla tube and actual petals of the dark mutant.
November 22, 2025 at 12:33 AM
This very late bloomer is SO DARK. Here is a more typical bloom for comparison. Note the stark change in saturation between the corolla tube and actual petals of the dark mutant.
A huge effort finally coming to fruition for B and their group. So excited to give this a whirl esp now that my cloning projects have ramped up substantially. Check this out 👇👇
Delighted to report that our group's passion project over the last 6+ years to make DNA cloning more accessible, efficient, and scalable using a software-assisted workflow called CloneCoordinate is now out in ACS Synbio!
pubs.acs.org/doi/10.1021/...
pubs.acs.org/doi/10.1021/...
CloneCoordinate: Open-Source Software for Collaborative DNA Construction
Custom DNA constructs have never been more common or important in the life sciences. Many researchers therefore devote substantial time and effort to molecular cloning, aided by abundant computer-aide...
pubs.acs.org
November 21, 2025 at 9:43 PM
A huge effort finally coming to fruition for B and their group. So excited to give this a whirl esp now that my cloning projects have ramped up substantially. Check this out 👇👇
The spinach seems lively today...
November 21, 2025 at 4:48 PM
The spinach seems lively today...
Exploring the living world, with whatever means you have, without any sifting for grander purpose or ulterior motives, is such a unique high. There is so much beauty and so many stories to tell around the proverbial campfire, and so many people are missing out.
Gotta fix this.
Gotta fix this.
November 21, 2025 at 2:47 PM
Exploring the living world, with whatever means you have, without any sifting for grander purpose or ulterior motives, is such a unique high. There is so much beauty and so many stories to tell around the proverbial campfire, and so many people are missing out.
Gotta fix this.
Gotta fix this.
Mom loved watching the pipetting robot run. Also peep the sport fishing shirt; my late dad's she uses as a gardening shirt.
November 20, 2025 at 5:32 PM
Mom loved watching the pipetting robot run. Also peep the sport fishing shirt; my late dad's she uses as a gardening shirt.
Waking up the mixologist...
November 20, 2025 at 3:34 PM
Waking up the mixologist...
Reposted by Sebastian S. Cocioba
Very happy to see this piece out in @plosbiology.org, on the bacterial immune systems and microbial communities. It was a great team effort with Rafael Custodio, @brockhurstlab.bsky.social , @brownlab.bsky.social, and Edze Westra! 🦠🧫 #phagesky #mevosky
journals.plos.org/plosbiology/...
journals.plos.org/plosbiology/...
Bacterial immune systems as causes and consequences of microbiome structure
Bacterial immune systems have evolved in response to diverse molecular "parasites", yet their ecological roles remain poorly understood. This Essay explores how interactions between mobile genetic ele...
journals.plos.org
November 19, 2025 at 6:35 PM
Very happy to see this piece out in @plosbiology.org, on the bacterial immune systems and microbial communities. It was a great team effort with Rafael Custodio, @brockhurstlab.bsky.social , @brownlab.bsky.social, and Edze Westra! 🦠🧫 #phagesky #mevosky
journals.plos.org/plosbiology/...
journals.plos.org/plosbiology/...
Happy International Mens Day!
If you are a teen, find a role model that exemplifies the honorable virtues of masculinity and strive toward compassion.
If you are an adult, strive to be a pillar of your community...but also go get a colonoscopy and check your prostate please.
If you are a teen, find a role model that exemplifies the honorable virtues of masculinity and strive toward compassion.
If you are an adult, strive to be a pillar of your community...but also go get a colonoscopy and check your prostate please.
November 19, 2025 at 9:20 PM
Happy International Mens Day!
If you are a teen, find a role model that exemplifies the honorable virtues of masculinity and strive toward compassion.
If you are an adult, strive to be a pillar of your community...but also go get a colonoscopy and check your prostate please.
If you are a teen, find a role model that exemplifies the honorable virtues of masculinity and strive toward compassion.
If you are an adult, strive to be a pillar of your community...but also go get a colonoscopy and check your prostate please.
As depressing as the regression of the laws around the deregulation of genetically modified plants may be, the few years the SECURE rules were active gave way to glowing plants, nutrient-dense tomatoes, and a hunger for more consumer-facing innovations.
Precedence.
Hope.
Precedence.
Hope.
November 19, 2025 at 6:42 PM
As depressing as the regression of the laws around the deregulation of genetically modified plants may be, the few years the SECURE rules were active gave way to glowing plants, nutrient-dense tomatoes, and a hunger for more consumer-facing innovations.
Precedence.
Hope.
Precedence.
Hope.
I *love* flowers so much. Look at my lil Alice goooooo. Proud dad. 🥰💚
November 19, 2025 at 5:44 PM
I *love* flowers so much. Look at my lil Alice goooooo. Proud dad. 🥰💚
I feel like this could be used for science somehow, but also baking is science and I want an excuse to make statistically significant inroads into the ideal pancake recipe lol
November 19, 2025 at 2:39 PM
I feel like this could be used for science somehow, but also baking is science and I want an excuse to make statistically significant inroads into the ideal pancake recipe lol
Reposted by Sebastian S. Cocioba
Blue Soup pub target journal
November 19, 2025 at 6:41 AM
Blue Soup pub target journal
Truly the most important thing of this entire gig, by far. I haven't had real health insurance in YEARS. More than anything I'm so thankful for the chance to take care of myself. Worth every penny.
November 19, 2025 at 5:26 AM
Truly the most important thing of this entire gig, by far. I haven't had real health insurance in YEARS. More than anything I'm so thankful for the chance to take care of myself. Worth every penny.
Reposted by Sebastian S. Cocioba
Our lab's new CS student is working on our supercomputers in lab and wants us to move off Ubuntu bc package manager reasons, and suggests Manjaro, Pop! (even tho same pkgmngr), or Debian. For the comp (bio) people in my feed, thoughts?
November 18, 2025 at 9:50 PM
Our lab's new CS student is working on our supercomputers in lab and wants us to move off Ubuntu bc package manager reasons, and suggests Manjaro, Pop! (even tho same pkgmngr), or Debian. For the comp (bio) people in my feed, thoughts?
"We have rupture disks at home..."
Found a nice bladed gizmo that cuts perfect circles of anything up to 0.4mm thick with a tungsten blade. Very clean once you get the blade depth dialed in. Identical disks. Time to test all the sheet plastics, lol.
a.co/d/2daeOJK
Found a nice bladed gizmo that cuts perfect circles of anything up to 0.4mm thick with a tungsten blade. Very clean once you get the blade depth dialed in. Identical disks. Time to test all the sheet plastics, lol.
a.co/d/2daeOJK
November 18, 2025 at 9:42 PM
"We have rupture disks at home..."
Found a nice bladed gizmo that cuts perfect circles of anything up to 0.4mm thick with a tungsten blade. Very clean once you get the blade depth dialed in. Identical disks. Time to test all the sheet plastics, lol.
a.co/d/2daeOJK
Found a nice bladed gizmo that cuts perfect circles of anything up to 0.4mm thick with a tungsten blade. Very clean once you get the blade depth dialed in. Identical disks. Time to test all the sheet plastics, lol.
a.co/d/2daeOJK
Reposted by Sebastian S. Cocioba
Nature research paper: Florigen activation complex forms via multifaceted assembly in Arabidopsis
go.nature.com/4pd26f8
go.nature.com/4pd26f8
Florigen activation complex forms via multifaceted assembly in Arabidopsis - Nature
In flowering plants, DNA–FD–14-3-3 recruits FT to the florigen activation complex both through DNA–FT interactions and by reducing liquid phase condensation of FD protein, which promotes dimerization, leading to FT recruitment.
go.nature.com
November 18, 2025 at 10:50 AM
Nature research paper: Florigen activation complex forms via multifaceted assembly in Arabidopsis
go.nature.com/4pd26f8
go.nature.com/4pd26f8
One of the most interesting documentaries of early radio technology I have ever seen. Worth a full viewing; analog magic.
youtu.be/wHenisSTUQY?...
youtu.be/wHenisSTUQY?...
Crystals Go to War, 1943
YouTube video by Awareness Bureau
youtu.be
November 18, 2025 at 4:18 AM
One of the most interesting documentaries of early radio technology I have ever seen. Worth a full viewing; analog magic.
youtu.be/wHenisSTUQY?...
youtu.be/wHenisSTUQY?...