Tobias Lenz
@biotobi.bsky.social
Professor of Evolutionary Immunogenomics @uni-hamburg.de
Evolutionary Genetics, Eco-Immunology, Host-Parasite Coevolution, Evolutionary Medicine, MHC/HLA. Only research-related posts.
http://www.biologie.uni-hamburg.de/evolutionaryimmunogenomics
Evolutionary Genetics, Eco-Immunology, Host-Parasite Coevolution, Evolutionary Medicine, MHC/HLA. Only research-related posts.
http://www.biologie.uni-hamburg.de/evolutionaryimmunogenomics
Reposted by Tobias Lenz
To argue "infections" are an extrinsic factor to heritability is bizarre to me - as if aging takes place in a vacuum.
Infections are part of longevity. Infection resistance is heritable (e.g. AMP polymorphisms in mammals, insects).
I don't disagree longevity is highly heritable... 1/2
Infections are part of longevity. Infection resistance is heritable (e.g. AMP polymorphisms in mammals, insects).
I don't disagree longevity is highly heritable... 1/2
🆕 @science.org
Revising the heritability of lifespan, from 25% to ~50%, by correcting for extrinsic factors
science.org/doi/10.1126/...
Revising the heritability of lifespan, from 25% to ~50%, by correcting for extrinsic factors
science.org/doi/10.1126/...
January 30, 2026 at 7:00 AM
To argue "infections" are an extrinsic factor to heritability is bizarre to me - as if aging takes place in a vacuum.
Infections are part of longevity. Infection resistance is heritable (e.g. AMP polymorphisms in mammals, insects).
I don't disagree longevity is highly heritable... 1/2
Infections are part of longevity. Infection resistance is heritable (e.g. AMP polymorphisms in mammals, insects).
I don't disagree longevity is highly heritable... 1/2
Reposted by Tobias Lenz
🔔HIRI has opened a new call to recruit Group Leaders. If you are interested in opening an RNA Biology and Infection lab, join us! Deadline: February 15. More info here 👇
January 28, 2026 at 3:06 PM
🔔HIRI has opened a new call to recruit Group Leaders. If you are interested in opening an RNA Biology and Infection lab, join us! Deadline: February 15. More info here 👇
Deadline for #SMBE2026 abstract submission is coming up (Feb 3)!
Consider symposium S14 "Evolution of Host-Pathogen Interactions in the Genomic Age", organized by @jcwinternitz.bsky.social, @arcova.bsky.social, @michalvinkler.bsky.social and @diyarhamidi.bsky.social.
Consider symposium S14 "Evolution of Host-Pathogen Interactions in the Genomic Age", organized by @jcwinternitz.bsky.social, @arcova.bsky.social, @michalvinkler.bsky.social and @diyarhamidi.bsky.social.
Abstract submission & Award applications for SMBE 2026 are now open!
Submit your research and apply for SMBE awards via the submission portal.
📝 Read more & submit here: smbe2026.org/abstracts
And symposium selection is now finalized!
👉 See all accepted symposia: smbe2026.org/programme
#SMBE2026
Submit your research and apply for SMBE awards via the submission portal.
📝 Read more & submit here: smbe2026.org/abstracts
And symposium selection is now finalized!
👉 See all accepted symposia: smbe2026.org/programme
#SMBE2026
January 27, 2026 at 8:06 AM
Deadline for #SMBE2026 abstract submission is coming up (Feb 3)!
Consider symposium S14 "Evolution of Host-Pathogen Interactions in the Genomic Age", organized by @jcwinternitz.bsky.social, @arcova.bsky.social, @michalvinkler.bsky.social and @diyarhamidi.bsky.social.
Consider symposium S14 "Evolution of Host-Pathogen Interactions in the Genomic Age", organized by @jcwinternitz.bsky.social, @arcova.bsky.social, @michalvinkler.bsky.social and @diyarhamidi.bsky.social.
Reposted by Tobias Lenz
Tha'ts what scientists want too. We need AI that makes sure you don't break the dishes (or centrifuge)
January 16, 2026 at 8:36 AM
Tha'ts what scientists want too. We need AI that makes sure you don't break the dishes (or centrifuge)
Please share: We are hosting the 2026 DZG evolutionary biology graduate meeting at Uni Hamburg on March 25-27: "Interactions and Coevolution: from Molecules to Species". #PhD students, early postdocs and advanced Master students in evolutionary biology are welcome to register! t1p.de/dzg2026evolbio
January 13, 2026 at 4:48 PM
Please share: We are hosting the 2026 DZG evolutionary biology graduate meeting at Uni Hamburg on March 25-27: "Interactions and Coevolution: from Molecules to Species". #PhD students, early postdocs and advanced Master students in evolutionary biology are welcome to register! t1p.de/dzg2026evolbio
Reposted by Tobias Lenz
The human pangenome continues to grow and improve! Release 2 is here! Click through for the details, but this is a pretty amazing dataset including not just the phased assemblies, but PacBio HiFi, ONT Ultralong, Dovetail/Illumina Hi-C, PacBio Kinnex, and Illumina WGS for all samples
📢 HPRC Release 2 is here!
Now with phased genomes from 200+ individuals, a 5x increase from Release 1.
Explore sequencing data, assemblies, annotations & alignments in our interactive data explorer ⬇️:
humanpangenome.org/hprc-data-re...
Now with phased genomes from 200+ individuals, a 5x increase from Release 1.
Explore sequencing data, assemblies, annotations & alignments in our interactive data explorer ⬇️:
humanpangenome.org/hprc-data-re...
May 12, 2025 at 1:52 PM
The human pangenome continues to grow and improve! Release 2 is here! Click through for the details, but this is a pretty amazing dataset including not just the phased assemblies, but PacBio HiFi, ONT Ultralong, Dovetail/Illumina Hi-C, PacBio Kinnex, and Illumina WGS for all samples
Reposted by Tobias Lenz
Establish your own independent research group as Group Leader - AI in Biology.
We’re looking for individuals interested in bridging innovations in machine learning/AI with modern biology.
embl.wd103.myworkdayjobs.com/en-US/EMBL/d...
We’re looking for individuals interested in bridging innovations in machine learning/AI with modern biology.
embl.wd103.myworkdayjobs.com/en-US/EMBL/d...
September 11, 2025 at 7:24 AM
Establish your own independent research group as Group Leader - AI in Biology.
We’re looking for individuals interested in bridging innovations in machine learning/AI with modern biology.
embl.wd103.myworkdayjobs.com/en-US/EMBL/d...
We’re looking for individuals interested in bridging innovations in machine learning/AI with modern biology.
embl.wd103.myworkdayjobs.com/en-US/EMBL/d...
Reposted by Tobias Lenz
“Everyone thinks their genes are the cause for them getting an age-related disease, it’s actually your immune system.” - @erictopol.bsky.social the author of Super Agers on #HealthandVeritas podcast
pod.link/1588414491/e... @thehowie.bsky.social @hmkyale.bsky.social
pod.link/1588414491/e... @thehowie.bsky.social @hmkyale.bsky.social
pod.link
September 11, 2025 at 3:04 PM
“Everyone thinks their genes are the cause for them getting an age-related disease, it’s actually your immune system.” - @erictopol.bsky.social the author of Super Agers on #HealthandVeritas podcast
pod.link/1588414491/e... @thehowie.bsky.social @hmkyale.bsky.social
pod.link/1588414491/e... @thehowie.bsky.social @hmkyale.bsky.social
Reposted by Tobias Lenz
Applications due Monday September 15 for the International Event Grants! These grants support symposia, workshops, courses, and other evolutionary biology events, including virtual events. Learn more and apply now: rb.gy/76fgi
September 11, 2025 at 3:16 PM
Applications due Monday September 15 for the International Event Grants! These grants support symposia, workshops, courses, and other evolutionary biology events, including virtual events. Learn more and apply now: rb.gy/76fgi
Reposted by Tobias Lenz
I've written a short blog post introducing "The Art of Visualization with ggplot2"!
This book is all about the end-to-end process of creating charts with #ggplot2 📊 including data wrangling, sketching, and styling your plots!
nrennie.rbind.io/blog/art-of-...
#RStats #DataViz #TidyTuesday
This book is all about the end-to-end process of creating charts with #ggplot2 📊 including data wrangling, sketching, and styling your plots!
nrennie.rbind.io/blog/art-of-...
#RStats #DataViz #TidyTuesday
Introducing The Art of Visualization with ggplot2 – Nicola Rennie
I’ve written a book! This blog post gives a brief introduction to The Art of Visualization with ggplot2, a book of data visualization case studies showing the end-to-end process of building charts, st...
nrennie.rbind.io
September 11, 2025 at 2:32 PM
I've written a short blog post introducing "The Art of Visualization with ggplot2"!
This book is all about the end-to-end process of creating charts with #ggplot2 📊 including data wrangling, sketching, and styling your plots!
nrennie.rbind.io/blog/art-of-...
#RStats #DataViz #TidyTuesday
This book is all about the end-to-end process of creating charts with #ggplot2 📊 including data wrangling, sketching, and styling your plots!
nrennie.rbind.io/blog/art-of-...
#RStats #DataViz #TidyTuesday
Reposted by Tobias Lenz
📣New today!
📄Haplotype analysis reveals pleiotropic disease associations in the HLA region
🧑🤝🧑 @jkpritch.bsky.social @finngen.bsky.social & colleagues
📄Haplotype analysis reveals pleiotropic disease associations in the HLA region
🧑🤝🧑 @jkpritch.bsky.social @finngen.bsky.social & colleagues
Haplotype analysis reveals pleiotropic disease associations in the HLA region
The HLA region plays an important role in human health but is often excluded in large-scale
GWASs. We performed haplotype-based associations from genotype data to investigate
pleiotropy across thousan...
www.cell.com
July 10, 2025 at 4:51 PM
📣New today!
📄Haplotype analysis reveals pleiotropic disease associations in the HLA region
🧑🤝🧑 @jkpritch.bsky.social @finngen.bsky.social & colleagues
📄Haplotype analysis reveals pleiotropic disease associations in the HLA region
🧑🤝🧑 @jkpritch.bsky.social @finngen.bsky.social & colleagues
Reposted by Tobias Lenz
Some PIs will stop at nothing to motivate their lab members. 🧪
July 12, 2025 at 11:41 AM
Some PIs will stop at nothing to motivate their lab members. 🧪
Join the annual meeting of the Society for Immune Polymorphism (SIP), November 3-5, Netherlands!
A meeting for everyone interested in polymorphic immune molecules (e.g. #MHC/#TCR) and their functional diversity across species.
Early bird/Abstract deadline is Aug 15:
sip-sassenheim.org
A meeting for everyone interested in polymorphic immune molecules (e.g. #MHC/#TCR) and their functional diversity across species.
Early bird/Abstract deadline is Aug 15:
sip-sassenheim.org
July 11, 2025 at 1:44 PM
Join the annual meeting of the Society for Immune Polymorphism (SIP), November 3-5, Netherlands!
A meeting for everyone interested in polymorphic immune molecules (e.g. #MHC/#TCR) and their functional diversity across species.
Early bird/Abstract deadline is Aug 15:
sip-sassenheim.org
A meeting for everyone interested in polymorphic immune molecules (e.g. #MHC/#TCR) and their functional diversity across species.
Early bird/Abstract deadline is Aug 15:
sip-sassenheim.org
Reposted by Tobias Lenz
📣 2 #Immunology #Summer_Schools that might be of interest to you:
If you are working on adaptive immune receptor repertoire:
ut.ee/en/content/c...
If you want to get deeper into new advances in Immunology:
focis2025.univ-rouen.fr/page.php?pag...
#ImmunoSky
If you are working on adaptive immune receptor repertoire:
ut.ee/en/content/c...
If you want to get deeper into new advances in Immunology:
focis2025.univ-rouen.fr/page.php?pag...
#ImmunoSky
Computational Immunology Summer School
Join the Computational Immunology Summer School to explore the fascinating world of Adaptive Immune Receptor Repertoires (AIRRs), mastering cutting-edge bioinformatics tools and lab techniques to uncover the secrets of immune system diversity.
ut.ee
April 11, 2025 at 8:55 AM
📣 2 #Immunology #Summer_Schools that might be of interest to you:
If you are working on adaptive immune receptor repertoire:
ut.ee/en/content/c...
If you want to get deeper into new advances in Immunology:
focis2025.univ-rouen.fr/page.php?pag...
#ImmunoSky
If you are working on adaptive immune receptor repertoire:
ut.ee/en/content/c...
If you want to get deeper into new advances in Immunology:
focis2025.univ-rouen.fr/page.php?pag...
#ImmunoSky
Reposted by Tobias Lenz
'Compared with the patients’ doctors, the AI model more often failed to detect the presence of disease in Black patients or women, as well in those 40yrs or younger. Wn the researchers looked at race and sex combined, Black women fell to the bottom, with the AI not detecting disease in half of them'
AI models miss disease in Black and female patients
Analysis of chest x-rays underscores need for monitoring artificial intelligence tools for bias, experts say
www.science.org
April 11, 2025 at 9:06 AM
'Compared with the patients’ doctors, the AI model more often failed to detect the presence of disease in Black patients or women, as well in those 40yrs or younger. Wn the researchers looked at race and sex combined, Black women fell to the bottom, with the AI not detecting disease in half of them'
Reposted by Tobias Lenz
Interested in starting your research group in AI and applications to science? Check out our upcoming online event for DFG funded opportunities in Goettingen!
The DFG is funding independent research groups in AI (tinyurl.com/36f5m6kd). If you're interested in coming to Göttingen (Germany) by applying for one of these groups, we have an online event to inform you what the process is and how we could support you (tinyurl.com/yfpeambm). Check it out!
Förderinitiative „Künstliche Intelligenz“
tinyurl.com
April 11, 2025 at 11:39 AM
Interested in starting your research group in AI and applications to science? Check out our upcoming online event for DFG funded opportunities in Goettingen!
Reposted by Tobias Lenz
Your research matters! Contribute to the future of #EvolutionaryBiology by submitting your Abstract to #ESEB2025.
🔬 Explore over 50 topics, including:
✅ #Evolution in all its aspects
✅ #Genetics & #Genomics
✅ New Frontiers and more!
📩 Submit now: eseb2025.com/call-for-abs...
🔬 Explore over 50 topics, including:
✅ #Evolution in all its aspects
✅ #Genetics & #Genomics
✅ New Frontiers and more!
📩 Submit now: eseb2025.com/call-for-abs...
April 9, 2025 at 12:38 PM
Your research matters! Contribute to the future of #EvolutionaryBiology by submitting your Abstract to #ESEB2025.
🔬 Explore over 50 topics, including:
✅ #Evolution in all its aspects
✅ #Genetics & #Genomics
✅ New Frontiers and more!
📩 Submit now: eseb2025.com/call-for-abs...
🔬 Explore over 50 topics, including:
✅ #Evolution in all its aspects
✅ #Genetics & #Genomics
✅ New Frontiers and more!
📩 Submit now: eseb2025.com/call-for-abs...
Reposted by Tobias Lenz
📢 new paper alert for the primate and genomics nerds. telomere to telomere ape genomes. I led MHC annotations on this work w/ @biotobi.bsky.social and @meyerbritta.bsky.social And hey it’s my first nature paper 🥳 www.nature.com/articles/s41...
Complete sequencing of ape genomes - Nature
Complete sequences of chromosomes telomere-to-telomere from chimpanzee, bonobo, gorilla, Bornean orangutan, Sumatran orangutan and siamang provide a comprehensive and valuable resource for future evol...
www.nature.com
April 9, 2025 at 3:19 PM
📢 new paper alert for the primate and genomics nerds. telomere to telomere ape genomes. I led MHC annotations on this work w/ @biotobi.bsky.social and @meyerbritta.bsky.social And hey it’s my first nature paper 🥳 www.nature.com/articles/s41...
Reposted by Tobias Lenz
Medicine on a Larger Scale: Global Histories of Social Medicine, eds @ahlie.bsky.social, Jeremy Greene, and me, will be available open access from @cambridgeup.bsky.social in May 2025. In a world of growing health inequity, radical social medicine has never been more urgent!
#histstm #histmed #sts
#histstm #histmed #sts
Medicine on a Larger Scale
Cambridge Core - History of Medicine - Medicine on a Larger Scale
www.cambridge.org
April 8, 2025 at 5:06 AM
Medicine on a Larger Scale: Global Histories of Social Medicine, eds @ahlie.bsky.social, Jeremy Greene, and me, will be available open access from @cambridgeup.bsky.social in May 2025. In a world of growing health inequity, radical social medicine has never been more urgent!
#histstm #histmed #sts
#histstm #histmed #sts
Reposted by Tobias Lenz
Come join us at beautiful UBC! The King Lab is recruiting a Post-doc Fellow to develop mathematical theory on infectious disease evolution and emergence, together with Ben Ashby (SFU) #zoonoses #biodiversity www.zoology.ubc.ca/kinglab/join...
Join Us! | King Lab
Are you interested in joining the King Lab? More information here!
www.zoology.ubc.ca
March 31, 2025 at 1:22 AM
Come join us at beautiful UBC! The King Lab is recruiting a Post-doc Fellow to develop mathematical theory on infectious disease evolution and emergence, together with Ben Ashby (SFU) #zoonoses #biodiversity www.zoology.ubc.ca/kinglab/join...
Reposted by Tobias Lenz
IMBA is recruiting a Junior Group Leader! Are you interested in starting your own lab, pursuing curiosity-driven basic research in the life sciences? Apply now to our group leader position. The deadline is May 28. Link is below.
March 28, 2025 at 11:15 AM
IMBA is recruiting a Junior Group Leader! Are you interested in starting your own lab, pursuing curiosity-driven basic research in the life sciences? Apply now to our group leader position. The deadline is May 28. Link is below.
Proudly presenting Dr. Artemis Efstratiou, who recently defended her PhD. She worked on variation of #MHC immune genes and dynamics of the T cell receptor repertoire in sticklebacks under different experimental conditions. Congratulations, Artemis! 🥳🎉 www.biologie.uni-hamburg.de/en/forschung...
March 26, 2025 at 7:17 AM
Proudly presenting Dr. Artemis Efstratiou, who recently defended her PhD. She worked on variation of #MHC immune genes and dynamics of the T cell receptor repertoire in sticklebacks under different experimental conditions. Congratulations, Artemis! 🥳🎉 www.biologie.uni-hamburg.de/en/forschung...
I just noticed this new header above the website of #MolecularEcologyResources. I'm sure that there are vast numbers of 'healthcare professionals' who will want to read our paper on MHC diversity in sticklebacks (😂), but what about the other few remaining scientsts? Just asking, @wiley.com ...
March 25, 2025 at 11:07 AM
I just noticed this new header above the website of #MolecularEcologyResources. I'm sure that there are vast numbers of 'healthcare professionals' who will want to read our paper on MHC diversity in sticklebacks (😂), but what about the other few remaining scientsts? Just asking, @wiley.com ...
Reposted by Tobias Lenz
Hello Blue world!
I recently migrated from the old Twitter as I got tired of the continuous bombardment of far-right propaganda.
I intend to use this account mainly for scientific exchange with a pinch of politics.
So, why not start with a summary of our recent paper?
doi.org/10.1186/s130...
I recently migrated from the old Twitter as I got tired of the continuous bombardment of far-right propaganda.
I intend to use this account mainly for scientific exchange with a pinch of politics.
So, why not start with a summary of our recent paper?
doi.org/10.1186/s130...
Admixture as a source for HLA variation in Neolithic European farming communities - Genome Biology
Background The northern European Neolithic is characterized by two major demographic events: immigration of early farmers from Anatolia at 7500 years before present, and their admixture with local wes...
doi.org
March 24, 2025 at 2:13 PM
Hello Blue world!
I recently migrated from the old Twitter as I got tired of the continuous bombardment of far-right propaganda.
I intend to use this account mainly for scientific exchange with a pinch of politics.
So, why not start with a summary of our recent paper?
doi.org/10.1186/s130...
I recently migrated from the old Twitter as I got tired of the continuous bombardment of far-right propaganda.
I intend to use this account mainly for scientific exchange with a pinch of politics.
So, why not start with a summary of our recent paper?
doi.org/10.1186/s130...