CarpenterLab
carpenterlab.bsky.social
CarpenterLab
@carpenterlab.bsky.social
LncRNA, innate immunity, macrophages
Reposted by CarpenterLab
A mouse circadian proteome atlas @cp-molcell.bsky.social
www.cell.com/molecular-ce...
January 10, 2026 at 4:17 AM
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”never-ending rapid growth in biomedical science has created an unsustainable hypercompetitive system that is discouraging even the most outstanding prospective students from entering our profession--and making it difficult for seasoned investigators to produce their best work”
Rescuing US biomedical research from its systemic flaws - PubMed
The long-held but erroneous assumption of never-ending rapid growth in biomedical science has created an unsustainable hypercompetitive system that is discouraging even the most outstanding prospective students from entering our profession--and making it difficult for seasoned investigators to produ …
pubmed.ncbi.nlm.nih.gov
January 10, 2026 at 4:37 AM
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@biorxivpreprint.bsky.social Mettl3-catalyzed m6A methylation determines CD8+ T cell differentiation fate in tumor
www.biorxiv.org/content/10.6...
January 7, 2026 at 4:33 AM
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💥New paper alert!💥 What’s better than starting 2026 with an @annualreviews.bsky.social #Immunology, often a once-in-a-life honor ❤️?! Check it out if you want to know everything about type III interferons #IFN! Thanks to my wonderful team for their amazing work 🤗 doi.org/10.1146/annu...
Molecular, Cellular, Tissue, and Organismal Functions of Type III Interferons
Type III interferons are essential immune mediators playing pleiotropic roles during health and disease. In this review, we highlight the molecular and cellular pathways that lead to the production of...
doi.org
January 5, 2026 at 5:50 PM
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Worth noting that even as Trump bombs Venezuela to unilaterally seize Maduro on domestic US charges, the ICC judges who voted to investigate US war crimes in Afghanistan face such severe US banking sanctions that they are for all intents and purposes excluded from modern life.
‘It’s surreal’: US sanctions lock International Criminal Court judge out of daily life
Canadian judge Kimberly Prost is unable to use credit cards, transfer money or book everyday services in what she calls an attack on the independence of the judiciary
www.irishtimes.com
January 3, 2026 at 4:04 PM
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January 2, 2026 at 1:13 AM
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Very cool paper showing a NAMPT activator that restores NAD+ in the brain can prevent Alzheimer's onset in an amyloid-driven 5xFAD mouse model. More evidence of a metabolic basis for neurodegenerative diseases.

www.cell.com/cell-reports...
Pharmacologic reversal of advanced Alzheimer’s disease in mice and identification of potential therapeutic nodes in human brain
Chaubey et al. demonstrate that restoration of brain resilience reverses advanced disease in two different mouse models of Alzheimer’s disease (AD), challenging the century-long dogma of AD irreversib...
www.cell.com
January 2, 2026 at 3:45 AM
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“There has been erosion of trust in science & public health & medicine,” vaccine & infectious disease expert @peterhotezmdphd.bsky.social said in response to the Trump administration’s cuts to vaccine and medical research. “It’s a terrible tragedy,” said Dr. Francis Collins, former NIH director.
‘This is immoral’: Public Health experts respond to funding cuts to science & medicine 
Over the course of the year, the Trump administration cut billions in funding for the National Institutes of Health, and $500 million worth of mRNA vaccine research. “There has been erosion of trust in science and public health and medicine,” said Dr. Peter Hotez, co-director of the Center for Vaccine Development at the Texas Children’s Hospital. “But it’s not random, this occurred deliberately by bad actors for political motivation.” Dr. Francis Collins, the former director of the NIH, said he’s never seen anything like this. Cuts to NIH resulted in the cancellation of 383 clinical trials affecting 74,000 trial participants. “Many of these people very serious cancers for which we don't have a great answer, but maybe we're in the middle of discovering one, and then the trial gets stopped, and all that data is lost, and those people are basically left to drift,” Dr. Collins said. “This is immoral to drop somebody into that space.”
www.msnbc.com
December 20, 2025 at 7:35 PM
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Amid NIH funding delays, reversals and uncertainty, a scientist at Harvard who studies breast cancer has lost one-third of her lab employees and wonders if she can continue her research experiments. n.pr/4a4N3zD
After NIH grant cuts, breast cancer research at Harvard slowed, and lab workers left
Amid NIH funding delays, reversals and uncertainty, a scientist at Harvard who studies breast cancer has lost one-third of her lab employees and wonders if she can continue her research experiments.
n.pr
December 9, 2025 at 10:04 AM
Congratulations to Dr. Christy Montano on a fantastic defense. We are all incredibly proud of you.
December 4, 2025 at 5:49 AM
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If you read and watch one thing today it should be this pice accompanying @agawande.bsky.social documentary.
"As of November 5th, it estimated that U.S.A.I.D.’s dismantling has already caused the deaths of six hundred thousand people, two-thirds of them children."
www.newyorker.com/culture/the-...
The Shutdown of U.S.A.I.D. Has Already Killed Hundreds of Thousands
The short documentary “Rovina’s Choice” tells the story of what goes when aid goes.
www.newyorker.com
November 6, 2025 at 5:18 PM
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The President's Postdoctoral Fellowship Program is one of the most coveted & prestigious positions for UC graduates. It gives a hiring incentive to campuses who hire recipients for a tenure track position. What a DAMN travesty.

This is capitulation to Trump's demand letter & anti-diversity agenda.
A devastating set of decisions on the part of UC leadership to withdraw support from our nationally recognized postdoc program that prioritizes research excellence combined with addressing our university public service mission. www.insidehighered.com/news/faculty...
UC to Stop Funding Systemwide Postdoc Program
Established in 1984 to encourage women and minority Ph.D.s to pursue academia, the program has attracted right-wing criticism for prioritizing diverse candidates.
www.insidehighered.com
November 5, 2025 at 9:07 PM
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This article presents the end of the PPFP as a done deal, but it’s not—until the chancellors’ meeting this afternoon.
UC to Stop Funding Systemwide Postdoc Program
Established in 1984 to encourage women and minority Ph.D.s to pursue academia, the program has attracted right-wing criticism for prioritizing diverse candidates.
www.insidehighered.com
November 5, 2025 at 7:43 PM
We are very proud of Valeriya for obtaining the Pfizer trainee award for her work on Gaplinc #Cytokines2025
November 5, 2025 at 12:13 AM
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#Cytokines2025 has begun- looking forward to a few days of networking, especially with #IFN friends from outside 🇨🇦 when it has been too long 😀
Despite the challenge of travel to the US at the moment, still 20 countries represented this year 🌎

#Cytokines25 @cytokinesociety.bsky.social
November 3, 2025 at 12:23 AM
We are excited to share our recent results on a new lncrna that functions to regulate proliferation in thp1 cells. This is the thesis work of Christy Montano.
CRISPRi Screen Identifies a Novel Growth Suppressor lncRNA, INSTAR, in Human Monocytes https://www.biorxiv.org/content/10.1101/2025.10.30.685589v1
November 2, 2025 at 12:57 AM
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🧪#Immunology
October 31, 2025 at 12:10 AM
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While the feds continue to play stupid games, SNAP recipients are set to lose food aid for the next month. In the Bay Area, a growing number of restaurants are stepping up to help, and we're maintaining the list. Share with anyone who needs it. www.coyotemedia.org/these-bay-ar...
These Bay Area Restaurants Are Offering Free Food to SNAP Recipients
Amid a government shutdown that will cut off aid for 42 million Americans, local food scene folks plan to pick up the slack.
www.coyotemedia.org
October 27, 2025 at 11:52 PM
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October 19, 2025 at 4:07 AM
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Maud Menten was born in Canada in 1879 and completed her UG and MD education at University of Toronto. As a research assistant with Leonor Michaelis in 1912, they wrote the classic paper describing the “Michaelis-Menten” model of enzyme kinetics.. #WomenInScience
October 16, 2025 at 1:02 AM
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Today my @nytimes.com colleagues and I are launching a new series called Lost Science. We interview US scientists who can no longer discover something new about our world, thanks to this year‘s cuts. Here is my first interview with a scientist who studied bees and fires. Gift link: nyti.ms/3IWXbiE
nyti.ms
October 8, 2025 at 11:29 PM
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Strong statement today from UC's Academic Senate:
October 3, 2025 at 9:58 PM
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EXCLUSIVE: In her first interview all year, Susan Monarez, CDC director for only 29 days, tells me why Trump/RFK fired her and where this is all headed.

The CDC director is an “inherently political position, but that doesn’t mean that it has to be politically compromised”, she tells @nature.com.
Exclusive: ex-CDC director talks about why she was fired
“I would never do that, as a scientist,” Susan Monarez says of being asked to approve changes to vaccine recommendations without knowing the details.
www.nature.com
October 2, 2025 at 11:15 AM