Cryo Mariena
@cryomariena.bsky.social
I like big scopes + I cannot lie. Struct bio + mat sci. Boricua. Pastafarian. Opinions = my own. #cryoeming since 2004. She/Her
Reposted by Cryo Mariena
We are looking for a computational postdoc to work with us on new optimisation algorithms to make #RELION even better. Join our bubbly team at the @mrclmb.bsky.social in Cambridge, UK. 🤗 RTs appreciated.
mrc.tal.net/vx/appcentre...
mrc.tal.net/vx/appcentre...
Quick Check Needed
mrc.tal.net
October 29, 2025 at 9:17 AM
We are looking for a computational postdoc to work with us on new optimisation algorithms to make #RELION even better. Join our bubbly team at the @mrclmb.bsky.social in Cambridge, UK. 🤗 RTs appreciated.
mrc.tal.net/vx/appcentre...
mrc.tal.net/vx/appcentre...
And, I probably won't travel home this winter, because not only are the flight schedules atrocious, they cost an arm and a leg, even with family chipping in. I'm anticipating being in a foul mood this winter.
October 29, 2025 at 1:15 AM
And, I probably won't travel home this winter, because not only are the flight schedules atrocious, they cost an arm and a leg, even with family chipping in. I'm anticipating being in a foul mood this winter.
Nearly $60 more per pay period (semi-monthly) to cover my son and I under my job's health insurance plan. Private plan and my employer covers a TON of the plan. I didn't vote for this fuckery.
October 29, 2025 at 1:14 AM
Nearly $60 more per pay period (semi-monthly) to cover my son and I under my job's health insurance plan. Private plan and my employer covers a TON of the plan. I didn't vote for this fuckery.
When, after a couple of weeks of back and forth, imaging, and confusion, the kindest (and most hilarious NP) tells you: not cancer! Phewwwww. The best part is sharing the news with the fam and work peeps who have been most understanding and kind.
October 21, 2025 at 11:37 PM
When, after a couple of weeks of back and forth, imaging, and confusion, the kindest (and most hilarious NP) tells you: not cancer! Phewwwww. The best part is sharing the news with the fam and work peeps who have been most understanding and kind.
Reposted by Cryo Mariena
Time for a thread!🧵 How different is the molecular organization of thylakoids in “higher” plants🌱? To find out, we teamed up with @profmattjohnson.bsky.social to dive into spinach chloroplasts with #CryoET ❄️🔬. Curious? ..Read on!
#TeamTomo #PlantScience 🧪 🧶🧬 🌾
elifesciences.org/articles/105...
1/🧵
#TeamTomo #PlantScience 🧪 🧶🧬 🌾
elifesciences.org/articles/105...
1/🧵
September 25, 2025 at 6:00 PM
Time for a thread!🧵 How different is the molecular organization of thylakoids in “higher” plants🌱? To find out, we teamed up with @profmattjohnson.bsky.social to dive into spinach chloroplasts with #CryoET ❄️🔬. Curious? ..Read on!
#TeamTomo #PlantScience 🧪 🧶🧬 🌾
elifesciences.org/articles/105...
1/🧵
#TeamTomo #PlantScience 🧪 🧶🧬 🌾
elifesciences.org/articles/105...
1/🧵
Reposted by Cryo Mariena
We have a preprint of a book chapter for you: Structural Analysis of Membrane Proteins in Cell-Derived Microvesicles.
We describe how to image membrane proteins in mid-sized vesicles using cryo-electron tomography
zenodo.org/records/1717...
We describe how to image membrane proteins in mid-sized vesicles using cryo-electron tomography
zenodo.org/records/1717...
Structural Analysis of Membrane Proteins in Cell-Derived Microvesicles
zenodo.org
September 22, 2025 at 12:36 PM
We have a preprint of a book chapter for you: Structural Analysis of Membrane Proteins in Cell-Derived Microvesicles.
We describe how to image membrane proteins in mid-sized vesicles using cryo-electron tomography
zenodo.org/records/1717...
We describe how to image membrane proteins in mid-sized vesicles using cryo-electron tomography
zenodo.org/records/1717...
Reposted by Cryo Mariena
Boltz v2.2.1 out. A few improvements including support for .pdb templates, better treatment of stereochemistry in guidance potentials, and improved documentation. As always a great thank you to all those in the community who contributed via PR, raising issues or directly reporting issues to us.
September 9, 2025 at 1:31 PM
Boltz v2.2.1 out. A few improvements including support for .pdb templates, better treatment of stereochemistry in guidance potentials, and improved documentation. As always a great thank you to all those in the community who contributed via PR, raising issues or directly reporting issues to us.
Reposted by Cryo Mariena
Mourning the loss of David Baltimore, a Nobel laureate and President Emeritus of Caltech. His groundbreaking work on reverse transcriptase reshaped our understanding of genetics and paved the way for advances in cancer and HIV research. A true giant in science. www.caltech.edu/about/news/c...
Caltech Mourns the Passing of President Emeritus and Nobel Laureate David Baltimore
David Baltimore, President Emeritus and the Judge Shirley Hufstedler Professor of Biology, Emeritus at Caltech and a co-recipient of the 1975 Nobel Prize in Physiology or Medicine, passed away on Sept...
www.caltech.edu
September 9, 2025 at 5:40 PM
Mourning the loss of David Baltimore, a Nobel laureate and President Emeritus of Caltech. His groundbreaking work on reverse transcriptase reshaped our understanding of genetics and paved the way for advances in cancer and HIV research. A true giant in science. www.caltech.edu/about/news/c...
Reposted by Cryo Mariena
Hi CryoEM Researchers - Here is a grid box for your 6mm HPF samples - The grid box has 2 pockets, each of which can hold a sandwich of 2 6mm HPF planchets or a single 6mm planchet - Offered in a variety of colors/pack sizes - A choice of lid types too - zurl.co/a5V2n
August 7, 2025 at 3:00 PM
Hi CryoEM Researchers - Here is a grid box for your 6mm HPF samples - The grid box has 2 pockets, each of which can hold a sandwich of 2 6mm HPF planchets or a single 6mm planchet - Offered in a variety of colors/pack sizes - A choice of lid types too - zurl.co/a5V2n
Reposted by Cryo Mariena
When I arrived to NYC as a postdoc, NYSBDG was my first local meeting, and I was blown way by the world-class quality of the science.
It's a great opportunity to meet the local #structbio & #cryoem community, and it's coming up in two weeks, so register now at the eventbrite link below!
It's a great opportunity to meet the local #structbio & #cryoem community, and it's coming up in two weeks, so register now at the eventbrite link below!
July 7, 2025 at 2:13 PM
When I arrived to NYC as a postdoc, NYSBDG was my first local meeting, and I was blown way by the world-class quality of the science.
It's a great opportunity to meet the local #structbio & #cryoem community, and it's coming up in two weeks, so register now at the eventbrite link below!
It's a great opportunity to meet the local #structbio & #cryoem community, and it's coming up in two weeks, so register now at the eventbrite link below!
Reposted by Cryo Mariena
Opportunity for computational chemist for cyclic peptide design at AbbVie (North Chicago USA) #CADD #CompChem #cheminformatics #AI #ML #ChemJobs #chemsky 🧪
jobs.smartrecruiters.com/AbbVie/37439...
jobs.smartrecruiters.com/AbbVie/37439...
Sr Scientist I/II Informatics - Peptide Design
Company Description: AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to ...
jobs.smartrecruiters.com
July 4, 2025 at 6:22 AM
Opportunity for computational chemist for cyclic peptide design at AbbVie (North Chicago USA) #CADD #CompChem #cheminformatics #AI #ML #ChemJobs #chemsky 🧪
jobs.smartrecruiters.com/AbbVie/37439...
jobs.smartrecruiters.com/AbbVie/37439...
Reposted by Cryo Mariena
Density animation generated using ChimeraX, using "cootmode" display settings from chimerax-trimmings.
Movie recorded thusly:
cofr showpivot false; movie record; rock y 30; wait 600; movie encode ~/Desktop/rock_movie_more.mp4 framerate 40; stop
Movie recorded thusly:
cofr showpivot false; movie record; rock y 30; wait 600; movie encode ~/Desktop/rock_movie_more.mp4 framerate 40; stop
June 13, 2025 at 6:34 PM
Density animation generated using ChimeraX, using "cootmode" display settings from chimerax-trimmings.
Movie recorded thusly:
cofr showpivot false; movie record; rock y 30; wait 600; movie encode ~/Desktop/rock_movie_more.mp4 framerate 40; stop
Movie recorded thusly:
cofr showpivot false; movie record; rock y 30; wait 600; movie encode ~/Desktop/rock_movie_more.mp4 framerate 40; stop
Reposted by Cryo Mariena
A tribute to George Sheldrick and SHELX and the impact on macromolecular and small-molecule crystallography
journals.iucr.org/a/issues/202...
journals.iucr.org/a/issues/202...
George M. Sheldrick (1942–2025)
In memory of George Sheldrick.
journals.iucr.org
May 6, 2025 at 11:34 AM
A tribute to George Sheldrick and SHELX and the impact on macromolecular and small-molecule crystallography
journals.iucr.org/a/issues/202...
journals.iucr.org/a/issues/202...
Reposted by Cryo Mariena
Hello BlueSky 🦋 I'm the Director of Graduate Studies in Cornell Chemistry. We're hiring a new Graduate Field Coordinator to help support our graduate program. Please apply or repost if you know someone great! tinyurl.com/3znxx4bh
Graduate Field Coordinator-Department of Chemistry and Chemical Biology
Graduate Field Coordinator-Department of Chemistry and Chemical Biology The Opportunity The Department of Chemistry and Chemical Biology is seeking a dedicated and detail-oriented Graduate Field Coord...
cornell.wd1.myworkdayjobs.com
June 10, 2025 at 11:42 PM
Hello BlueSky 🦋 I'm the Director of Graduate Studies in Cornell Chemistry. We're hiring a new Graduate Field Coordinator to help support our graduate program. Please apply or repost if you know someone great! tinyurl.com/3znxx4bh
Reposted by Cryo Mariena
So the crazy thing here is the company this is supposed to be about is Corning. The company famous for its glass research. And the across the board metric is a measure of how similar individual atom positions are in their CRYSTAL structures. So much is nuts here, but that should have been a red flag
May 17, 2025 at 1:16 PM
So the crazy thing here is the company this is supposed to be about is Corning. The company famous for its glass research. And the across the board metric is a measure of how similar individual atom positions are in their CRYSTAL structures. So much is nuts here, but that should have been a red flag
Wherever your atoms are, whatever form your energy took .... happy birthday to you and your sis. I miss you so much.
June 6, 2025 at 2:20 PM
Wherever your atoms are, whatever form your energy took .... happy birthday to you and your sis. I miss you so much.
Reposted by Cryo Mariena
We honor the bravery of those who risked everything on D-Day—and remember why they did.
Freedom demands vigilance, then and now.
“I have full confidence in your courage, devotion to duty, and skill in battle. We will accept nothing less than full victory.” — Gen. Dwight D. Eisenhower
Freedom demands vigilance, then and now.
“I have full confidence in your courage, devotion to duty, and skill in battle. We will accept nothing less than full victory.” — Gen. Dwight D. Eisenhower
June 6, 2025 at 1:34 PM
We honor the bravery of those who risked everything on D-Day—and remember why they did.
Freedom demands vigilance, then and now.
“I have full confidence in your courage, devotion to duty, and skill in battle. We will accept nothing less than full victory.” — Gen. Dwight D. Eisenhower
Freedom demands vigilance, then and now.
“I have full confidence in your courage, devotion to duty, and skill in battle. We will accept nothing less than full victory.” — Gen. Dwight D. Eisenhower
Reposted by Cryo Mariena
NSF budget would close down one of LIGO's sites. This would be, to put it lightly, a catastrophe for gravitational wave astronomy.
"In FY 2026 NSF will operate only one of the two sites
and will support a reduced level for technology development."
bsky.app/profile/hast...
"In FY 2026 NSF will operate only one of the two sites
and will support a reduced level for technology development."
bsky.app/profile/hast...
May 30, 2025 at 8:47 PM
NSF budget would close down one of LIGO's sites. This would be, to put it lightly, a catastrophe for gravitational wave astronomy.
"In FY 2026 NSF will operate only one of the two sites
and will support a reduced level for technology development."
bsky.app/profile/hast...
"In FY 2026 NSF will operate only one of the two sites
and will support a reduced level for technology development."
bsky.app/profile/hast...
And even viruses to pieces if the Eiffel Tower!
“From chocolate chips to computer chips” 🧪⚛️
Discover the cutting-edge characterization facilities at the Cornell Center for Materials Research (CCMR).Reach out to schedule a visit or discuss your needs! More info on becoming a user can be found here: www.ccmr.cornell.edu/facilities/b...
May 29, 2025 at 11:49 PM
And even viruses to pieces if the Eiffel Tower!
Reposted by Cryo Mariena
Danielle was one of Lena’s students 🧪
Revealing the Crystalline Architecture of Semicrystalline Ion Exchange Membranes for the Design of Conductive and Durable Alkaline Anion Exchange Membranes pubmed.ncbi.nlm.nih.gov/40415331/ #cryoem
May 28, 2025 at 5:02 AM
Danielle was one of Lena’s students 🧪
Hey friends, sorry I've been MIA. I was in hospital for about a week due to a bad reaction between two meds I was taking. I'm OK, but taking some time off to recover.
May 29, 2025 at 11:48 PM
Hey friends, sorry I've been MIA. I was in hospital for about a week due to a bad reaction between two meds I was taking. I'm OK, but taking some time off to recover.
21yrs ago I survived, we all did. I still remember the sounds, the sights. Some years are harder than others, this one has been quite terrible. The PTSD is real, rearing its head. The nightmares aren't as common these days, thankfully. My seat was 5B, aisle. 5th window, starting from that gate/door.
May 10, 2025 at 1:39 AM
21yrs ago I survived, we all did. I still remember the sounds, the sights. Some years are harder than others, this one has been quite terrible. The PTSD is real, rearing its head. The nightmares aren't as common these days, thankfully. My seat was 5B, aisle. 5th window, starting from that gate/door.
Reposted by Cryo Mariena
Not long after I started my lab, a prominent scientist told me it was “impossible” to be a successful PI and a mother
Don’t ever let the naysayers tell you it can’t be done - of course it can!
#HappyMothersDay this weekend to all the amazing scientist mamas raising their wonderful kids 🥰
Don’t ever let the naysayers tell you it can’t be done - of course it can!
#HappyMothersDay this weekend to all the amazing scientist mamas raising their wonderful kids 🥰
May 9, 2025 at 6:23 PM
Not long after I started my lab, a prominent scientist told me it was “impossible” to be a successful PI and a mother
Don’t ever let the naysayers tell you it can’t be done - of course it can!
#HappyMothersDay this weekend to all the amazing scientist mamas raising their wonderful kids 🥰
Don’t ever let the naysayers tell you it can’t be done - of course it can!
#HappyMothersDay this weekend to all the amazing scientist mamas raising their wonderful kids 🥰