@dbogani.bsky.social
Reposted
As the political climate around animal research becomes less supportive in the UK, it is our interest to argue for & protect organismal biology.
BBSRC opened a survey, which gives us a timely platform. Please fill & share link among colleagues. Deadline: 9/2
engagementhub.ukri.org/mrc-bbsrc/la...
BBSRC opened a survey, which gives us a timely platform. Please fill & share link among colleagues. Deadline: 9/2
engagementhub.ukri.org/mrc-bbsrc/la...
February 3, 2026 at 9:17 AM
As the political climate around animal research becomes less supportive in the UK, it is our interest to argue for & protect organismal biology.
BBSRC opened a survey, which gives us a timely platform. Please fill & share link among colleagues. Deadline: 9/2
engagementhub.ukri.org/mrc-bbsrc/la...
BBSRC opened a survey, which gives us a timely platform. Please fill & share link among colleagues. Deadline: 9/2
engagementhub.ukri.org/mrc-bbsrc/la...
An elegant approach using a mix of technologies and making the most of resources generated over many years of research into the canonical Wnt pathway.
And results which have the potential to andvance personalised treatment for some forms of cancer. Congrats @andrewwood.bsky.social and collaborators!
And results which have the potential to andvance personalised treatment for some forms of cancer. Congrats @andrewwood.bsky.social and collaborators!
Fresh insights reveal how cancer gene mutations drive tumour growth:
Andrew Wood (lead of our Degron Cluster) has co-led a team that created a comprehensive map that shows how hundreds of possible mutations in a key cancer gene influence tumour growth
nmgn.mrc.ukri.org/news/fresh-i...
Andrew Wood (lead of our Degron Cluster) has co-led a team that created a comprehensive map that shows how hundreds of possible mutations in a key cancer gene influence tumour growth
nmgn.mrc.ukri.org/news/fresh-i...
Fresh insights reveal how cancer gene mutations drive tumour growth | National Mouse Genetics Network
Scientists have created a comprehensive map showing how hundreds of possible mutations in a key cancer gene influence tumour growth, offering a new insight that could guide the development of […]
nmgn.mrc.ukri.org
February 2, 2026 at 3:10 PM
An elegant approach using a mix of technologies and making the most of resources generated over many years of research into the canonical Wnt pathway.
And results which have the potential to andvance personalised treatment for some forms of cancer. Congrats @andrewwood.bsky.social and collaborators!
And results which have the potential to andvance personalised treatment for some forms of cancer. Congrats @andrewwood.bsky.social and collaborators!
Reposted
Our Best Models Working Group can offer advice on the use of a range of model systems.
The next in our series highlighting our diverse expertise features Dr Andrew Wood, whose lab uses genome editing and targeted protein degradation to study genetic disease using cell lines, organoids, and mice.
The next in our series highlighting our diverse expertise features Dr Andrew Wood, whose lab uses genome editing and targeted protein degradation to study genetic disease using cell lines, organoids, and mice.
January 30, 2026 at 10:28 AM
Our Best Models Working Group can offer advice on the use of a range of model systems.
The next in our series highlighting our diverse expertise features Dr Andrew Wood, whose lab uses genome editing and targeted protein degradation to study genetic disease using cell lines, organoids, and mice.
The next in our series highlighting our diverse expertise features Dr Andrew Wood, whose lab uses genome editing and targeted protein degradation to study genetic disease using cell lines, organoids, and mice.
Reposted
Our Best Models Working Group can offer advice on the use of a range of model systems.
The next in our series of posts highlighting our diverse expertise features Dr Alex Whitworth, whose group uses Drosophila models of neurodegenerative diseases.
nmgn.mrc.ukri.org/working-grou...
The next in our series of posts highlighting our diverse expertise features Dr Alex Whitworth, whose group uses Drosophila models of neurodegenerative diseases.
nmgn.mrc.ukri.org/working-grou...
January 27, 2026 at 12:16 PM
Our Best Models Working Group can offer advice on the use of a range of model systems.
The next in our series of posts highlighting our diverse expertise features Dr Alex Whitworth, whose group uses Drosophila models of neurodegenerative diseases.
nmgn.mrc.ukri.org/working-grou...
The next in our series of posts highlighting our diverse expertise features Dr Alex Whitworth, whose group uses Drosophila models of neurodegenerative diseases.
nmgn.mrc.ukri.org/working-grou...
Reposted
📢 Job Alert 📢
Post-doc position at #LancasterUniversity working on the #MURIDAE project @mrcmousenetwork.bsky.social
Working with #genetic #preclinical models for #schizophrenia 🧠🧬🐭
Please repost!
www.jobs.ac.uk/job/DPW471/s...
Post-doc position at #LancasterUniversity working on the #MURIDAE project @mrcmousenetwork.bsky.social
Working with #genetic #preclinical models for #schizophrenia 🧠🧬🐭
Please repost!
www.jobs.ac.uk/job/DPW471/s...
Senior Research Associate at Lancaster University
An opportunity for an academic position as a Senior Research Associate is available, as advertised on jobs.ac.uk. Apply now and explore other academic job openings.
www.jobs.ac.uk
December 19, 2025 at 10:23 AM
📢 Job Alert 📢
Post-doc position at #LancasterUniversity working on the #MURIDAE project @mrcmousenetwork.bsky.social
Working with #genetic #preclinical models for #schizophrenia 🧠🧬🐭
Please repost!
www.jobs.ac.uk/job/DPW471/s...
Post-doc position at #LancasterUniversity working on the #MURIDAE project @mrcmousenetwork.bsky.social
Working with #genetic #preclinical models for #schizophrenia 🧠🧬🐭
Please repost!
www.jobs.ac.uk/job/DPW471/s...
Exciting times ahead!
The @mrc-tu.bsky.social and Dept of Biochemistry, @cam.ac.uk, @astra-zeneca.bsky.social, @cruk-si.bsky.social, and the MLC have been awarded a £3.4 million MRC Prosperity Partnership grant to fund research into understanding the toxicity of advanced therapeutics:
www.har.mrc.ac.uk/news/new-aca...
www.har.mrc.ac.uk/news/new-aca...
New academic-industry partnership has been funded by the Medical Research Council to uncover the safety and toxicity of nucleic-acid based therapeutics. | Mary Lyon Centre
The MRC Toxicology Unit and Department of Biochemistry at the University of Cambridge, AstraZeneca, Cancer Research UK Scotland Institute, and the Mary Lyon Centre at MRC Harwell have been awarded a £...
www.har.mrc.ac.uk
December 3, 2025 at 10:34 AM
Exciting times ahead!
Reposted
We welcome the government’s effort to provide a clear roadmap for the phasing out of the use of animals in research, while maintaining scientific rigour and safety standards.
Today the UK government has released a strategy to support the development, validation and uptake of alternative methods.
Read more: www.gov.uk/government/n...
Read more: www.gov.uk/government/n...
Animal testing to be phased out faster as UK unveils roadmap for alternative methods
New plan backs researchers to seize on new and developing opportunities to phase out animal tests with specific commitments for the coming years.
www.gov.uk
November 12, 2025 at 11:31 AM
We welcome the government’s effort to provide a clear roadmap for the phasing out of the use of animals in research, while maintaining scientific rigour and safety standards.
Reposted
We plan to facilitate replacement training at our Advance training centre and lead the @mrcmousenetwork.bsky.social Best Models Working Group, which provides a forum for researchers to learn about alternative models and connect with experts in other systems
www.har.mrc.ac.uk/services/rep...
www.har.mrc.ac.uk/services/rep...
Replacement of Animals in Medical Research | Mary Lyon Centre
Animals are currently used where there is no scientifically satisfactory alternative, but there has been considerable progress in developing new methodologies that could replace the use of animals in ...
www.har.mrc.ac.uk
November 12, 2025 at 11:31 AM
We plan to facilitate replacement training at our Advance training centre and lead the @mrcmousenetwork.bsky.social Best Models Working Group, which provides a forum for researchers to learn about alternative models and connect with experts in other systems
www.har.mrc.ac.uk/services/rep...
www.har.mrc.ac.uk/services/rep...
Our guys offering their expertise 😊🙌🏻
Sharing what we know again!
Decades of experience distilled into a workshop at #FELASA2025 in which, our senior team talk about how to reduce severity of animal procedures right from the start of a project using GA mice, and limiting welfare issues. #3Rs #AnimalWelfare #training
Decades of experience distilled into a workshop at #FELASA2025 in which, our senior team talk about how to reduce severity of animal procedures right from the start of a project using GA mice, and limiting welfare issues. #3Rs #AnimalWelfare #training
June 2, 2025 at 3:24 PM
Our guys offering their expertise 😊🙌🏻
Reposted
Top quality teamwork by @cost-teatime.bsky.social repositories WG to address a key issue in maximising the impact of #Home-cageMonitoring. From the first working group meeting @mrcharwell.bsky.social in Oct’24 to V1 of the preprint in May’25!! Take a sneak peak 👀 here: osf.io/preprints/os...
May 24, 2025 at 4:29 PM
Top quality teamwork by @cost-teatime.bsky.social repositories WG to address a key issue in maximising the impact of #Home-cageMonitoring. From the first working group meeting @mrcharwell.bsky.social in Oct’24 to V1 of the preprint in May’25!! Take a sneak peak 👀 here: osf.io/preprints/os...
We are co-organising another international conference: Organoids Are Us is a symposium to report and discuss the latest advances in this exciting modality to tackle unanswered biological and clinical questions. For more info nmgn.mrc.ukri.org/news/we-are-...
We are co-organising Organoids Are Us 2025. Register now! | National Mouse Genetics Network
The MRC National Mouse Genetics Network, in collaboration with the Cancer Research UK (CRUK) Scotland Institute, is organising Organoids Are Us 2025, a symposium that incorporates both basic and clini...
nmgn.mrc.ukri.org
May 23, 2025 at 11:01 AM
Reposted
Last month was a busy one for the Network's scientists. Some of our MURIDAE cluster members and associates attended the @britishneuro.bsky.social (BNA) #BNA2025 and organised a symposium. Read our short report on the work they showcased! nmgn.mrc.ukri.org/news/bna-fes... @mrcharwell.bsky.social
BNA Festival of Neuroscience - We were there! | National Mouse Genetics Network
The British Neuroscience Association (BNA) Festival of Neuroscience 2025 was held in Liverpool from the 27th to the 30th of April. The Festival certainly started with a bang, as Liverpool […]
nmgn.mrc.ukri.org
May 20, 2025 at 12:47 PM
Last month was a busy one for the Network's scientists. Some of our MURIDAE cluster members and associates attended the @britishneuro.bsky.social (BNA) #BNA2025 and organised a symposium. Read our short report on the work they showcased! nmgn.mrc.ukri.org/news/bna-fes... @mrcharwell.bsky.social
Reposted
Check out this post from @dbogani.bsky.social @mrcharwell.bsky.social about a new tool to assist scientists, policy makers, funders and reviewers in eliminating persistent sex bias in biomedical research:
thenode.biologists.com/new-framewor...
thenode.biologists.com/new-framewor...
New Framework Aims to Eliminate Sex Bias in Preclinical Research - the Node
An important new resource for researchers, reviewers, and funders has been developed with major contributions from the Mary Lyon Centre at MRC Harwell. A
thenode.biologists.com
May 16, 2025 at 6:33 AM
Check out this post from @dbogani.bsky.social @mrcharwell.bsky.social about a new tool to assist scientists, policy makers, funders and reviewers in eliminating persistent sex bias in biomedical research:
thenode.biologists.com/new-framewor...
thenode.biologists.com/new-framewor...
Reposted
May 19, 2025 at 6:37 PM
Reposted
Sponsoring #Pint25 at a packed @oxfordblue.bsky.social and our own @rsbains.bsky.social going through the journey to passive behaviour monitoring powered by #AI @mrcharwell.bsky.social
May 19, 2025 at 6:47 PM
Sponsoring #Pint25 at a packed @oxfordblue.bsky.social and our own @rsbains.bsky.social going through the journey to passive behaviour monitoring powered by #AI @mrcharwell.bsky.social
Reposted
Beautiful morning here in Liverpool!
If you are attending #BNA2025 @britishneuro.bsky.social check out our symposium this afternoon, Room 3A
S21: The MRC National Mouse Genetics Network: Translating genetic findings using preclinical mouse models
@mrcmousenetwork.bsky.social
If you are attending #BNA2025 @britishneuro.bsky.social check out our symposium this afternoon, Room 3A
S21: The MRC National Mouse Genetics Network: Translating genetic findings using preclinical mouse models
@mrcmousenetwork.bsky.social
April 29, 2025 at 9:23 AM
Beautiful morning here in Liverpool!
If you are attending #BNA2025 @britishneuro.bsky.social check out our symposium this afternoon, Room 3A
S21: The MRC National Mouse Genetics Network: Translating genetic findings using preclinical mouse models
@mrcmousenetwork.bsky.social
If you are attending #BNA2025 @britishneuro.bsky.social check out our symposium this afternoon, Room 3A
S21: The MRC National Mouse Genetics Network: Translating genetic findings using preclinical mouse models
@mrcmousenetwork.bsky.social
Check out also our post to see how the @mrcharwell.bsky.social contributed to the work and what we think it will me for #preclinical in vivo studies and better #TranslationalResearch outcomes www.har.mrc.ac.uk/news/new-fra...
April 25, 2025 at 10:35 AM
Check out also our post to see how the @mrcharwell.bsky.social contributed to the work and what we think it will me for #preclinical in vivo studies and better #TranslationalResearch outcomes www.har.mrc.ac.uk/news/new-fra...
Reposted
Very full schedule at our #IMGCglasgow workshop last week, delivered by MitoCluster team @robpitceathly.bsky.social, Carlo Viscomi, @mitogene.bsky.social, and @jim-ca.bsky.social. A pleasure to attend, thanks for the invite @mrcmousenetwork.bsky.social & IMGS! 🧬
#mitochondria #MouseModels #ECR
#mitochondria #MouseModels #ECR
April 15, 2025 at 10:09 AM
Very full schedule at our #IMGCglasgow workshop last week, delivered by MitoCluster team @robpitceathly.bsky.social, Carlo Viscomi, @mitogene.bsky.social, and @jim-ca.bsky.social. A pleasure to attend, thanks for the invite @mrcmousenetwork.bsky.social & IMGS! 🧬
#mitochondria #MouseModels #ECR
#mitochondria #MouseModels #ECR
Reposted
Not a network talk but we really enjoyed this one by @davidashbrook.bsky.social on transgenic models of Alzheimer’s Disease on different genetic backgrounds. Loads of data and incredible imaging!
April 9, 2025 at 8:13 AM
Not a network talk but we really enjoyed this one by @davidashbrook.bsky.social on transgenic models of Alzheimer’s Disease on different genetic backgrounds. Loads of data and incredible imaging!
Reposted
What a welcome by #Glasgow City Chambers! One of the highlights of this #IMGCGlasgow!
@yannherault.bsky.social
@yannherault.bsky.social
April 7, 2025 at 5:57 PM
What a welcome by #Glasgow City Chambers! One of the highlights of this #IMGCGlasgow!
@yannherault.bsky.social
@yannherault.bsky.social
Reposted
This morning session is Network loaded, starting with Sevda Boyanova from the @ukdri.ac.uk talking about the standardised phenotyping pipelines established for Alzheimer’s and frontotemporal dementia mouse models at the @mrcharwell.bsky.social Great attendance despite the early start! #IMGCGlasgow
April 8, 2025 at 7:47 AM
This morning session is Network loaded, starting with Sevda Boyanova from the @ukdri.ac.uk talking about the standardised phenotyping pipelines established for Alzheimer’s and frontotemporal dementia mouse models at the @mrcharwell.bsky.social Great attendance despite the early start! #IMGCGlasgow
Reposted
Our Director Owen Sansom describing decades long work that is now involving the Cancer Cluster to generate and characterise mouse models of colorectal cancer that more faithfully recapitulate human disease #IMGCGlasgow
April 8, 2025 at 8:13 AM
Our Director Owen Sansom describing decades long work that is now involving the Cancer Cluster to generate and characterise mouse models of colorectal cancer that more faithfully recapitulate human disease #IMGCGlasgow
Reposted
And finally Claus Nerlow form the Haem Cluster describing models of acute leukaemia regulated by GATA2 mutations #IMGCGlasgow
April 8, 2025 at 8:25 AM
And finally Claus Nerlow form the Haem Cluster describing models of acute leukaemia regulated by GATA2 mutations #IMGCGlasgow
Reposted
Ageing Cluster member Nicholas Schaum presenting the cluster and the work he’s doing to advance our understanding of the ageing process and the possible intervention points for a healthier life using #mouse cohorts at different age points #IMGCGlasgow #AgeingResearch @mrcharwell.bsky.social
April 7, 2025 at 9:32 AM
Ageing Cluster member Nicholas Schaum presenting the cluster and the work he’s doing to advance our understanding of the ageing process and the possible intervention points for a healthier life using #mouse cohorts at different age points #IMGCGlasgow #AgeingResearch @mrcharwell.bsky.social