Djenet Bousbaine
@djenetbousbaine.bsky.social
Postdoc in microbiology and immunology @Stanford in the Fischbach lab, K99 NIH/NIAID fellow. PhD @MicrobiologyMit and @BostonChildrens in the Ploegh lab.
Reposted by Djenet Bousbaine
'The vaccine we all wear'
In @science.org , Postdoc @djenetbousbaine.bsky.social writes about her work in Institute Scholar @mfgrp.bsky.social lab exploring the possibility of non-invasive topical vaccines that could be applied directly to the skin: www.science.org/doi/10.1126/...
In @science.org , Postdoc @djenetbousbaine.bsky.social writes about her work in Institute Scholar @mfgrp.bsky.social lab exploring the possibility of non-invasive topical vaccines that could be applied directly to the skin: www.science.org/doi/10.1126/...
August 5, 2025 at 5:03 PM
'The vaccine we all wear'
In @science.org , Postdoc @djenetbousbaine.bsky.social writes about her work in Institute Scholar @mfgrp.bsky.social lab exploring the possibility of non-invasive topical vaccines that could be applied directly to the skin: www.science.org/doi/10.1126/...
In @science.org , Postdoc @djenetbousbaine.bsky.social writes about her work in Institute Scholar @mfgrp.bsky.social lab exploring the possibility of non-invasive topical vaccines that could be applied directly to the skin: www.science.org/doi/10.1126/...
Congrats @cmcclune.bsky.social and the rest of the team!
Check out this amazing new work from @sattelylab.bsky.social along with collaborator and @stanford-chemh.bsky.social Institute Scholar @pollyfordyce.bsky.social !
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Discovery of FoTO1 and Taxol genes enables biosynthesis of baccatin III - Nature
An approach that combines single-nucleus RNA sequencing and multiplexed perturbation identifies genes that enable the biosynthesis of direct precursors of the anti-cancer drug Taxol, whose curren...
www.nature.com
July 11, 2025 at 12:43 PM
Congrats @cmcclune.bsky.social and the rest of the team!
It’s truly an honor to receive this year’s
@science.org Noster Microbiome prize.
Here’s my essay on how we can engineer skin microbes to build topical vaccines:
@science.org Noster Microbiome prize.
Here’s my essay on how we can engineer skin microbes to build topical vaccines:
🎉 Congratulations to Djenet Bousbaine, winner of the 2025 NOSTER & Science Microbiome Prize for her work to illuminate how the immune system responds to the beneficial skin microbiome.
Learn more: scim.ag/4lVwpFx
Learn more: scim.ag/4lVwpFx
July 5, 2025 at 3:25 PM
It’s truly an honor to receive this year’s
@science.org Noster Microbiome prize.
Here’s my essay on how we can engineer skin microbes to build topical vaccines:
@science.org Noster Microbiome prize.
Here’s my essay on how we can engineer skin microbes to build topical vaccines:
Reposted by Djenet Bousbaine
Check out the Noster prize winning essays @science.org The vaccine we all wear: Skin microbiota can be engineered into topical vaccines | Science www.science.org/doi/10.1126/...
The vaccine we all wear: Skin microbiota can be engineered into topical vaccines
Skin microbiota can be engineered into topical vaccines
www.science.org
July 4, 2025 at 4:09 PM
Check out the Noster prize winning essays @science.org The vaccine we all wear: Skin microbiota can be engineered into topical vaccines | Science www.science.org/doi/10.1126/...
Reposted by Djenet Bousbaine
Check out this prize-winning essay by postdoc @djenetbousbaine.bsky.social on her work with @mfgrp.bsky.social @stanford-chemh.bsky.social 👏
Check out the Noster prize winning essays @science.org The vaccine we all wear: Skin microbiota can be engineered into topical vaccines | Science www.science.org/doi/10.1126/...
The vaccine we all wear: Skin microbiota can be engineered into topical vaccines
Skin microbiota can be engineered into topical vaccines
www.science.org
July 4, 2025 at 4:36 PM
Check out this prize-winning essay by postdoc @djenetbousbaine.bsky.social on her work with @mfgrp.bsky.social @stanford-chemh.bsky.social 👏
Check this beautiful work out of the Sattely lab by @cmcclune.bsky.social
Today in Nature we report a systematic strategy to activate & identify gene sets in plants. We identify 8 new genes from the yew tree's Taxol biosynthetic pathway, enabling us to engineer tobacco with 17- & 20-gene pathways to Taxol precursors baccatin III & deBz-deoxy-Taxol #SingleCell #secmet 🧬🧪🌾
Discovery of FoTO1 and Taxol genes enables biosynthesis of baccatin III - Nature
An approach that combines single-nucleus RNA sequencing and multiplexed perturbation identifies genes that enable the biosynthesis of direct precursors of the anti-cancer drug Taxol, whose curren...
www.nature.com
June 12, 2025 at 3:24 AM
Check this beautiful work out of the Sattely lab by @cmcclune.bsky.social
So thankful being able to work with you!
What an amazing story that was such a blast to collaborate on with @mfgrp.bsky.social lab!!! Phenomenal work led by @djenetbousbaine.bsky.social and all co-authors!! Unroll this thread and be amazed 🤯👇🏾
Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. @djenetbousbaine.bsky.social led the charge... @natureportfolio.bsky.social 1/55
December 24, 2024 at 4:54 PM
So thankful being able to work with you!
Reposted by Djenet Bousbaine
Scientists turned a harmless skin bacterium into a powerful vaccine delivery tool, boosting immunity in the lungs and nose.
@mfgrp.bsky.social @djenetbousbaine.bsky.social @nature.com
t.co/xXXCJx5VYm
#ImmunoSky 🧪
@mfgrp.bsky.social @djenetbousbaine.bsky.social @nature.com
t.co/xXXCJx5VYm
#ImmunoSky 🧪
December 21, 2024 at 4:32 PM
Scientists turned a harmless skin bacterium into a powerful vaccine delivery tool, boosting immunity in the lungs and nose.
@mfgrp.bsky.social @djenetbousbaine.bsky.social @nature.com
t.co/xXXCJx5VYm
#ImmunoSky 🧪
@mfgrp.bsky.social @djenetbousbaine.bsky.social @nature.com
t.co/xXXCJx5VYm
#ImmunoSky 🧪
Reposted by Djenet Bousbaine
#Immunology by First release now @science.org
Identification of APCs in the gut that promote Treg differentiation and how tolerance to food antigens is influenced by helminth infection
https://buff.ly/3DjNQ1e
By Maria Canesso, @danmucida.bsky.social , @victora.bsky.social and colleagues.
Identification of APCs in the gut that promote Treg differentiation and how tolerance to food antigens is influenced by helminth infection
https://buff.ly/3DjNQ1e
By Maria Canesso, @danmucida.bsky.social , @victora.bsky.social and colleagues.
December 19, 2024 at 8:08 PM
#Immunology by First release now @science.org
Identification of APCs in the gut that promote Treg differentiation and how tolerance to food antigens is influenced by helminth infection
https://buff.ly/3DjNQ1e
By Maria Canesso, @danmucida.bsky.social , @victora.bsky.social and colleagues.
Identification of APCs in the gut that promote Treg differentiation and how tolerance to food antigens is influenced by helminth infection
https://buff.ly/3DjNQ1e
By Maria Canesso, @danmucida.bsky.social , @victora.bsky.social and colleagues.
Reposted by Djenet Bousbaine
A commensal bacterium triggers systemic antibody responses via skin lymphoid structures and can be engineered as a topical vaccine – great therapeutic potential!
Two studies in @nature.com.web.brid.gy by the Fischbach and Belkaid labs
tinyurl.com/5yahn47t
tinyurl.com/4n4btxap
Two studies in @nature.com.web.brid.gy by the Fischbach and Belkaid labs
tinyurl.com/5yahn47t
tinyurl.com/4n4btxap
December 15, 2024 at 5:07 PM
A commensal bacterium triggers systemic antibody responses via skin lymphoid structures and can be engineered as a topical vaccine – great therapeutic potential!
Two studies in @nature.com.web.brid.gy by the Fischbach and Belkaid labs
tinyurl.com/5yahn47t
tinyurl.com/4n4btxap
Two studies in @nature.com.web.brid.gy by the Fischbach and Belkaid labs
tinyurl.com/5yahn47t
tinyurl.com/4n4btxap
Reposted by Djenet Bousbaine
Two fascinating papers just out in Nature @natureportfolio.bsky.social:
www.nature.com/articles/s41...
www.nature.com/articles/s41...
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Skin autonomous antibody production regulates host-microbiota interactions - Nature
Nature - Skin autonomous antibody production regulates host-microbiota interactions
www.nature.com
December 12, 2024 at 2:05 PM
Two fascinating papers just out in Nature @natureportfolio.bsky.social:
www.nature.com/articles/s41...
www.nature.com/articles/s41...
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Check out our last pub. from @mfgrp.bsky.social al lab! We discovered that skin commensal microbes induce systemic and local B cell responses upon colonization and took advantage of this knowledge to create topical vaccines using engineered skin microbes. Please read the thread for details.
Today we report that an engineered skin bacterium, swabbed gently on the head of a mouse, can unleash a potent antibody response against a pathogen. Could lead to topical vaccines that are applied in a cream. @djenetbousbaine.bsky.social led the charge... @natureportfolio.bsky.social 1/55
December 12, 2024 at 12:33 AM
Check out our last pub. from @mfgrp.bsky.social al lab! We discovered that skin commensal microbes induce systemic and local B cell responses upon colonization and took advantage of this knowledge to create topical vaccines using engineered skin microbes. Please read the thread for details.