Dr Liz Ergique
@drlizergique.bsky.social
Following the white rabbit
Medical Science Rocks.
Medical Science Rocks.
Sale temps
Certains élus veulent limoger l'idiot du village RFK Jr.
C'était passé sous le radar. Témoignage glaçant. La directrice limogée du CDC, la Dr Susan Monarez, s'exprime sur les pressions exercées par RFK Jr.
Quand la pseudo science fait la loi à la vraie science. 🤢😣
C'était passé sous le radar. Témoignage glaçant. La directrice limogée du CDC, la Dr Susan Monarez, s'exprime sur les pressions exercées par RFK Jr.
Quand la pseudo science fait la loi à la vraie science. 🤢😣
December 13, 2025 at 8:39 AM
Sale temps
Gros challenge pour les early adopter
"One small molecule for man, one giant leap for mankind with obesity"
sciencedirect.com/science/arti...
But the very high amounts of drug in pills relative to injectable peptides, due to such poor bioavailability, means we need to be watchful for new side effects when these pills get widely used
sciencedirect.com/science/arti...
But the very high amounts of drug in pills relative to injectable peptides, due to such poor bioavailability, means we need to be watchful for new side effects when these pills get widely used
One small molecule for man, one giant leap for mankind with obesity
The ATTAIN-1 trial launches a new era in obesity care. Orforglipron, the first oral small-molecule GLP-1 receptor agonist to complete a phase 3 clinic…
sciencedirect.com
December 13, 2025 at 8:34 AM
Gros challenge pour les early adopter
paper’s conclusions regarding the carcinogenicity of glyphosate were solely based on unpublished studies from Monsanto, ignoring other outside, published research.
Science journal retracts study on safety of Monsanto’s Roundup: ‘serious ethical concerns’ #Science #HealthandMedicine #PublicHealth #Monsanto #Roundup #ResearchEthics
Science journal retracts study on safety of Monsanto’s Roundup: ‘serious ethical concerns’
Paper published in 2000 found glyphosate was not harmful, while internal emails later revealed company’s influence The journal Regulatory Toxicology and Pharmacology has formally retracted a sweeping...
purescience.news
December 6, 2025 at 6:11 PM
paper’s conclusions regarding the carcinogenicity of glyphosate were solely based on unpublished studies from Monsanto, ignoring other outside, published research.
Sale temps
To be real clear
This is not about evidence.
No new harm have been discovered.
This is about personal beliefs.
It's about power. It's about controlling you.
It WILL cause harm.
Panel Votes to End Recommendation for Hepatitis B Shots for All Newborns.
www.nytimes.com/2025/12/05/h...
This is not about evidence.
No new harm have been discovered.
This is about personal beliefs.
It's about power. It's about controlling you.
It WILL cause harm.
Panel Votes to End Recommendation for Hepatitis B Shots for All Newborns.
www.nytimes.com/2025/12/05/h...
Panel Votes to End Recommendation for Hepatitis B Shots for All Newborns
www.nytimes.com
December 6, 2025 at 5:55 PM
Sale temps
among the patients whose
surgery was delayed by more than 6 months was 2.6 times as high as that among those who underwent surgery sooner.
surgery was delayed by more than 6 months was 2.6 times as high as that among those who underwent surgery sooner.
A fantastic comprehensive review article w/ everything you need to know about Idiopathic Normal Pressure Hydrocephalus. Johnson and Williams share that idiopathic normal-pressure hydrocephalus is a common, frequently missed and potentially reversible neurologic condition in older adults. @nejm.org
December 6, 2025 at 5:52 PM
among the patients whose
surgery was delayed by more than 6 months was 2.6 times as high as that among those who underwent surgery sooner.
surgery was delayed by more than 6 months was 2.6 times as high as that among those who underwent surgery sooner.
« Lorsqu’on parle de protéger le caractère privé du cerveau, on ne joue pas à se faire peur. Avec ces technologies, on peut tenter de réparer les corps. Ou comme Elon Musk, nous rendre capables d’écrire un tweet avec la pensée et ouvrir un accès direct pour les compagnies à notre cerveau. »
« La machine ne se trompe pas. Celui qui est faillible, c’est le cobaye » : Arnaud Robert, tétraplégique, raconte l’étude clinique neurotechnologique qui a tenté de le réparer
Paralysé des quatre membres en 2022 après avoir glissé sur une plaque de glace, ce journaliste suisse de 48 ans a accepté, l’année suivante, de participer à un protocole de recherche fascinant, mêlant...
www.lemonde.fr
November 9, 2025 at 8:33 AM
« Lorsqu’on parle de protéger le caractère privé du cerveau, on ne joue pas à se faire peur. Avec ces technologies, on peut tenter de réparer les corps. Ou comme Elon Musk, nous rendre capables d’écrire un tweet avec la pensée et ouvrir un accès direct pour les compagnies à notre cerveau. »
RFK en pls. Intérêt du vaccin anti vrs en prévention de IC après 60 ans. Pas de signal myocardite après vaccin anti grippal. Meilleure efficacité high dose vaccin anti grippal.
📌 You can read all the JAMA, @jamacardiology.com, and @jamanetworkopen.com papers presented yesterday at #ESCCongress 2025.
ja.ma/3HNjMxM
ja.ma/3HNjMxM
August 31, 2025 at 6:20 AM
RFK en pls. Intérêt du vaccin anti vrs en prévention de IC après 60 ans. Pas de signal myocardite après vaccin anti grippal. Meilleure efficacité high dose vaccin anti grippal.
À 30k€/an ça fait cher le placebo. En tout cas la plaque amyloïde ne semblent pas être un bon surrogate endpoint.
August 22, 2025 at 4:20 PM
À 30k€/an ça fait cher le placebo. En tout cas la plaque amyloïde ne semblent pas être un bon surrogate endpoint.
Médical science rocks!
Some important progress in vaccines
1. Cancer vaccine, potentially universal, to rev up immune system
www.nature.com/articles/s41...
2. Lipid nanoparticle improvement for better safety and potency
www.nature.com/articles/s41...
3. mRNA delivery by capsule www.statnews.com/2025/07/16/s...
1. Cancer vaccine, potentially universal, to rev up immune system
www.nature.com/articles/s41...
2. Lipid nanoparticle improvement for better safety and potency
www.nature.com/articles/s41...
3. mRNA delivery by capsule www.statnews.com/2025/07/16/s...
Sensitization of tumours to immunotherapy by boosting early type-I interferon responses enables epitope spreading - Nature Biomedical Engineering
Lipid particles loaded with RNA coding for tumour-unspecific antigens can enhance early responses of type-I interferons, mediating the success of immune checkpoint inhibitors as well as epitope spread...
www.nature.com
July 18, 2025 at 10:04 PM
Médical science rocks!
Transhumanism at full speed. Whow….
The long-awaited results of the 2017 trial suggest that the approach can reduce the risk of mitochondrial disease—but not everyone is convinced.
Researchers announce babies born from a trial of three-person IVF
The long-awaited results of the 2017 trial suggest that the approach can reduce the risk of mitochondrial disease—but not everyone is convinced.
www.technologyreview.com
July 16, 2025 at 11:19 PM
Transhumanism at full speed. Whow….
The new gold
Spotlight on the gut-brain axis
A rapid expansion of new discoveries and knowledge lays the foundation for a new era in medicine
erictopol.substack.com/p/the-gut-br...
A rapid expansion of new discoveries and knowledge lays the foundation for a new era in medicine
erictopol.substack.com/p/the-gut-br...
The Gut-Brain Axis Takes Center Stage
A rapid expansion of new discoveries and knowledge lays the foundation for a new era in medicine
erictopol.substack.com
June 22, 2025 at 6:26 PM
The new gold
Covid in utero a very bad trip
Children exposed to COVID in utero had developmental delays at age 24 months:
🧠36% cognitive delays
🗣️64% communication delays
🏃57% had motor delays
🧪 Specific developmental delays were related to specific inflammation cytokines found in their cord blood at birth. buff.ly/AQSfBm9
#Medsky #Pedsky 🛟😷
🧠36% cognitive delays
🗣️64% communication delays
🏃57% had motor delays
🧪 Specific developmental delays were related to specific inflammation cytokines found in their cord blood at birth. buff.ly/AQSfBm9
#Medsky #Pedsky 🛟😷
June 19, 2025 at 4:36 AM
Covid in utero a very bad trip
Des car-t cells au car-m cells belles perspectives
Cells as living drugs is a big part of future medical approaches.
There's been so much about engineering T cells (CAR-T) for treatment of cancer and autoimmune diseases. But engineering macrophages (CAR-M) is next up for blocking inflammation.
www.nature.com/articles/s41...
There's been so much about engineering T cells (CAR-T) for treatment of cancer and autoimmune diseases. But engineering macrophages (CAR-M) is next up for blocking inflammation.
www.nature.com/articles/s41...
Targeting inflammation with chimeric antigen receptor macrophages using a signal switch - Nature Biomedical Engineering
Anti-TNF CAR macrophages show anti-inflammatory efficacy in both acute and chronic inflammatory disease mouse models.
www.nature.com
May 10, 2025 at 11:38 PM
Des car-t cells au car-m cells belles perspectives
JFK en PLS
Does the #shingles vaccine affect the probability of receiving a new diagnosis of dementia?
A new study of data from Australia suggests a potential preventive effect.
➡️ Read the full article: ja.ma/4jJg45t
#MedSky
A new study of data from Australia suggests a potential preventive effect.
➡️ Read the full article: ja.ma/4jJg45t
#MedSky
April 24, 2025 at 3:16 PM
JFK en PLS
Un peu de lumière ds le Parkinson
It has taken decades to get to this point, but stem cells for Parkinson's disease showing promise in 2 clinical trials
nature.com/articles/d41...
nature.com/articles/s41...
nature.com/articles/s41...
nature.com/articles/d41...
nature.com/articles/s41...
nature.com/articles/s41...
Clinical trials test the safety of stem-cell therapy for Parkinson’s disease
Transplanting dopamine-releasing neurons into the brain is a promising regenerative therapy for Parkinson’s disease. Two clinical trials show that it is safe, but more evidence is needed to prove its ...
nature.com
April 16, 2025 at 7:05 PM
Un peu de lumière ds le Parkinson
On va peut être redécouvrir les CB1 bloqueurs qui ont peut être être enterrés trop vite. Remembering rimonaban.
The brain-adipose tissue axis:
discovery of a new pathway for potential mitigation of stress-induced anxiety @naturemetabolism.bsky.social
www.nature.com/articles/s42...
discovery of a new pathway for potential mitigation of stress-induced anxiety @naturemetabolism.bsky.social
www.nature.com/articles/s42...
April 15, 2025 at 3:27 PM
On va peut être redécouvrir les CB1 bloqueurs qui ont peut être être enterrés trop vite. Remembering rimonaban.
Using germline DNA extracted from saliva, they derived polygenic risk scores from 130 variants known to be associated with an increased risk of prostate cancer.
A high polygenic risk score (PRS) for screening prostate cancer was superior to a PSA test or MRI for detecting clinically significant disease (Gleason ≥7). A big step forward for supporting utility of PRS @nejm.org
www.nejm.org/doi/full/10....
www.nejm.org/doi/full/10....
Assessment of a Polygenic Risk Score in Screening for Prostate Cancer | NEJM
The incidence of prostate cancer is increasing. Screening with an assay of prostate-specific
antigen (PSA) has a high rate for false positive results. Genomewide association studies
have identified...
www.nejm.org
April 10, 2025 at 5:15 AM
Using germline DNA extracted from saliva, they derived polygenic risk scores from 130 variants known to be associated with an increased risk of prostate cancer.
Quand on brûle des livres on connaît la suite
This is the literal destruction of knowledge.
Mississippi libraries are being ordered to remove academic research on race and gender from library databases.
mississippitoday.org/2025/04/08/m...
Mississippi libraries are being ordered to remove academic research on race and gender from library databases.
mississippitoday.org/2025/04/08/m...
Mississippi libraries ordered to delete academic research in response to state laws - Mississippi Today
The two research collections state officials ordered for deletion included material from professional journals, conference papers, books, student dissertations, periodicals and newspaper articles.
mississippitoday.org
April 9, 2025 at 5:36 AM
Quand on brûle des livres on connaît la suite
Make Darwin Great Again
April 6, 2025 at 8:31 PM
Make Darwin Great Again
Shingrix vaccin recombinant indiqué dans la prévention du zona et des névralgies post-zostériennes (NPZ) réduit le risque de démence d’environ 20%
A major paper @nature.com this week found a significant decline in dementia after an outdated Shingles vaccine.
I've reviewed the study and many other relevant ones here
erictopol.substack.com/p/the-shingl...
I've reviewed the study and many other relevant ones here
erictopol.substack.com/p/the-shingl...
The Shingles Vaccine and Reduction of Dementia
A compelling new study adds to the body of data supporting some protection provided by the vaccine
erictopol.substack.com
April 6, 2025 at 5:06 AM
Shingrix vaccin recombinant indiqué dans la prévention du zona et des névralgies post-zostériennes (NPZ) réduit le risque de démence d’environ 20%
Qd on commence à brûler des livres on finit par brûler des gens. Quid pour les data?
La destruction des données scientifiques aux États-Unis : un non-sens intellectuel, éthique mais aussi économique
La destruction des données scientifiques aux États-Unis : un non-sens intellectuel, éthique mais aussi économique
La destruction délibérée de bases de données scientifiques évoque de sombres souvenirs historiques. Elle représente une menace sérieuse pour l’avenir de la connaissance et la richesse des nations.
theconversation.com
April 2, 2025 at 2:52 PM
Qd on commence à brûler des livres on finit par brûler des gens. Quid pour les data?
Vive Darwin!
simple Trump solution. Defund Yale and data go away.🧪
As of March 30, there are approximately 529 measles cases across 20 states. Experts project that the Southwest outbreak, which has spread from West Texas to New Mexico, Oklahoma, and Kansas, could last up to a year as cases continue to rise.
Read this full thread for what to know. ⬇️ 1/11 🧵
Read this full thread for what to know. ⬇️ 1/11 🧵
April 2, 2025 at 2:49 PM
Vive Darwin!
Le retour au moyen âge se profile. Les vaccins sont en première ligne
Vaccine critic’s apparent selection to head HHS autism study shocks experts
The apparent choice of a major player in the anti-vaccine community to conduct an HHS study on autism has shocked vaccine experts.
www.statnews.com
March 27, 2025 at 6:39 AM
Le retour au moyen âge se profile. Les vaccins sont en première ligne
Transhumanism at full speed
The Business of Promoting Longevity and Healthspan
A crop of new consumer-facing companies with unconventional data collection
open.substack.com
March 23, 2025 at 10:39 PM
Transhumanism at full speed