Emiliano Martí 🇦🇷
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emilianomarti.bsky.social
Emiliano Martí 🇦🇷
@emilianomarti.bsky.social
https://non-mendelian.com

Geneticist. Interested in genetic conflicts and the origin of hybrid incompatibilities. PhD student in the Presgraves and Larracuente labs @ University of Rochester
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John Maynard Smith and Richard Lewontin at the University of Sussex, 9 March 1972.
October 30, 2025 at 3:56 PM
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Join us this Friday at 13:00 UTC for the first Internal Conflicts STN seminar of this academic year, featuring Laurence Hurst and Phil Madgwick! Details via internalconflictsstn.wordpress.com/seminars/, also on several upcoming seminars.
September 15, 2025 at 9:23 AM
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Take a sneak peak at The Paradox of the Organism at Google books books.google.com/books?hl=sv&...

Don’t forget to pre-order!
September 14, 2025 at 10:35 PM
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News in the history of molecular biology. The Science History Institute in Philadelphia has acquired a huge archive of correspondence and other scientific material from the pioneers of molecular biology (Franklin, Klug, Perutz, Delbrück etc, with items from Crick and Watson, too). 1/n
History of Molecular Biology Collection
This unparalleled collection includes Rosalind Franklin's historic 'Photo 51,' which revealed the double-helix structure of DNA.
www.sciencehistory.org
September 8, 2025 at 12:28 PM
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Another fun Morris memory:

Tinbergen was annoyed when grad students bought fish food instead of making their own. To him, it lacked the dignity of labour.
September 9, 2025 at 2:18 PM
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Giant endogenous viral elements in the genome of the model protist Euglena gracilis reveal past interactions with giant viruses https://pubmed.ncbi.nlm.nih.gov/40856505/
August 27, 2025 at 1:50 PM
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Opponent independent costs game vs. arms race.

Geoff Parker on the importance of picking good terms.
August 27, 2025 at 3:34 PM
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FlyBase, a Drosophila database, will lose a third of its team in early October because the Harvard grant that covered the employees’ salaries was canceled. Scientists warn that losing FlyBase could devastate fly research.

By @claudia-lopez.bsky.social

www.thetransmitter.org/community/ha...
Harvard University lays off fly database team
The layoffs jeopardize this resource, which has served more than 4,000 labs for about three decades.
www.thetransmitter.org
August 13, 2025 at 7:32 PM
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Interested in how new sex chromosomes evolve in birds? Our NSF-funded collaborative work with the (Daven) Presgraves lab at @urochester.bsky.social is out this week in @pnas.org. Check it out!

www.pnas.org/doi/10.1073/...
August 7, 2025 at 11:28 AM
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Gorgeous cover for @ellenclarke.bsky.social’s fantastic new book The Units of Life (OUP 2025).
August 4, 2025 at 5:22 PM
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I'm excited to announce our new biorxiv preprint, wherein we investigate the evolution of the weirdest genetic locus I've ever seen! Behold the tgr genes of the social amoeba, which mediate self/non-self discrimination during facultative multicellularity 🐅 🧵 1/
www.biorxiv.org/content/10.1...
Hypermutable hotspot enables the rapid evolution of self/non-self recognition genes in Dictyostelium
Cells require highly polymorphic receptors to perform accurate self/non-self recognition. In the amoeba Dicytostelium discoideum, polymorphic TgrB1 & TgrC1 proteins are used to bind sister cells and e...
www.biorxiv.org
August 5, 2025 at 12:56 AM
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I spoke to Renaud Pourpe (of @lonelypipette.bsky.social fame with @epigenetique.bsky.social) about the unique challenges faced by postdocs and early-career PIs worldwide on the transition from postdoc to PI.

Lots of useful advice shared (by others):

www.alba.network/diversity-po...

Check it out.
ALBA-IBRO Diversity Podcast - Season 2
Episode 4 is out. In season 2, we focus on the transition from postdoc to PI, highlighting the unique challenges faced by postdocs and early-career PIs worldwide. Hosted by the Lonely Pipette.
www.alba.network
August 2, 2025 at 11:01 PM
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Antisense transposon insertions into host genes trigger piRNA mediated immunity https://www.biorxiv.org/content/10.1101/2025.07.28.667215v1
August 1, 2025 at 3:32 AM
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You may recall I was trying to find the cover of an issue of @nature.com from 1980. Thanks to Tim at Customer Service, this is from the magazine's archive... Thanks to all! The weird beasts at the end of the double helices were drawn by Linda Sapienza, wife of the co-author of one of the papers.
June 30, 2025 at 9:45 AM
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The Gene's-Eye View of Evolution was published four years ago today.
July 21, 2025 at 8:09 PM
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Longdust, a new tool to identify highly repetitive STRs, VNTRs, satellite DNA and other low-complexity regions (LCRs). Similar to SDUST but for long regions.
github.com/lh3/longdust
GitHub - lh3/longdust: Identify long STRs, VNTRs, satellite DNA and other low-complexity regions in a genome
Identify long STRs, VNTRs, satellite DNA and other low-complexity regions in a genome - lh3/longdust
github.com
July 31, 2025 at 7:59 PM
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In 2020, NCBI considered to remove base quality from free-to-download SRA files. I responded and wrote two blog posts to argue against that. I don't know how much NCBI weighed on everyone's response but they are keeping quality in most SRA files nowadays. grants.nih.gov/grants/guide...
NOT-OD-20-108: Request for Information: Use of Cloud Resources and New File Formats for Sequence Read Archive Data
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Request for Information: Use of Cloud Resources and New File Formats for Sequence Read Archive Data NOT-OD-20-108. NIH
grants.nih.gov
July 31, 2025 at 8:57 PM
Happy to share our latest article, led by Tee Muirhead, now out in PNAS! We report the evolutionary genomics of the newly discovered neo-sex chromosomes in Myzomela — involving translocation, inversions & degeneration on the neo-W. doi.org/10.1073/pnas...
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
doi.org
July 28, 2025 at 8:02 PM
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Albuquerque characterized the satellitome of the pea aphid, with results suggesting that satDNAs contribute to genome evolution, biotype divergence, and the “fast-X” effect.

🔗 doi.org/10.1093/gbe/evaf104

#genome #satellitome
Exploring the Satellitome of the Pest Aphid Acyrthosiphon pisum (Hemiptera, Aphididae): Insights Into Genome Organization and Intraspecies Evolution
Abstract. Satellite DNAs (satDNAs), ubiquitous sequences in eukaryotic genomes, play a crucial role in genome organization, function, and evolution. The pe
doi.org
July 10, 2025 at 4:18 PM
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In this commentary article, Logan T. Edvalson and Amanda M. Larracuente discuss recently published #GENETICS and #G3journal papers that offer new understandings into the consequences of drive in genome and species evolution.

Read more: buff.ly/JowkdFt
June 26, 2025 at 8:02 PM
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We’re thrilled to announce the Spring 2025 recipients of the DeLill Nasser Award for Professional Development in Genetics! 🧬 Please join us in congratulating this season’s awardees. Read more in Genes to Genomes: buff.ly/p3vh1gx
June 25, 2025 at 4:08 PM
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The rest of Mendel's alleles characterized! So, out of 7 traits, 3 caused by TE insertions!!! (though apparently there are two different green alleles, one cause by a TE insertion, but another a promoter deletion allele)

www.nature.com/articles/s41...
Genomic and genetic insights into Mendel’s pea genes - Nature
Characterization of the genetic architecture underlying the 7 pairs of contrasting traits studied by Mendel and the over 70 additional agronomic traits in pea (Pisum sativum) reveals their m...
www.nature.com
April 26, 2025 at 2:15 AM
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Now available for preorder!

The Paradox of the Organism:
Adaptation and Internal Conflict, edited by me and Manus Patten, will be published by @harvardpress.bsky.social this fall.

Cover coming soon.
April 16, 2025 at 8:04 PM
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Reprogramming site-specific retrotransposon activity to new DNA sites @nature.com
www.nature.com/articles/s41...
April 9, 2025 at 4:41 PM
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A selfish gene in Drosophila has met its match: Trailblazer.

“An innovation in host responses to escalating genomic conflicts”
by @emilianomarti.bsky.social & Amanda Larracuente

highlights work from @peiwei-chen.bsky.social et al in PNAS.

FREE till May 24 at
authors.elsevier.com/a/1ktQOcQbJF...
April 4, 2025 at 1:45 PM