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Natural Product Reports @natprodreports.rsc.org · 14d

Be sure to read this review, part of our Industrial Perspective themed collection, by Stefano Donadio & co. from NAICONS Srl discussing the trends in metabolite discovery from Actinomycetes #secmet #natprod

Find it in full below👇

Trends in metabolite discovery from Actinomycetes

Covering: 2013 to 2023 In this review, we analyzed the scientific literature of the period 2013–2023 that reported novel specialized metabolites from the Actinomycetes, one of the most prolific…

pubs.rsc.org

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Emmanuele Severi @emmseveri.bsky.social · 15d

www.nature.com/articles/s44...

#microsky #phagesky #synbio

Non-model bacteria as platforms for endogenous gene expression in synthetic biology - Nature Reviews Bioengineering

Microbial synthetic biology might greatly benefit from the application of non-model organisms, which have been evolutionarily optimized for the production of specific proteins and metabolites. This Review discusses the design and application of endogenous production in non-model organisms.

www.nature.com

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Natural Product Reports @natprodreports.rsc.org · 16d

ICYMI: Nominations for the 2026 @natprodreports.rsc.org Emerging Investigator Lectureship are currently open! #chemsky #secmet #naturalproducts #synbio 🧪

⌛Deadline for nominations is 19 October 2025

Details on how to nominate can be found on our website here▶️rsc.li/npr-lectureship

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Dan Udwary @danudwary.secondarymetabolism.com · 24d

#secmet

Philmus Lab @ OSU @philmuslab.bsky.social · 24d

We are proud to be able to offer this as an OpenAccess article!
pmc.ncbi.nlm.nih.gov/articles/PMC.... Thank you to #NaturalProductReports for helping us.
#SecMet

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Ákos T Kovács @evolvedbiofilm.bsky.social · Aug 8

“principles of experimental design that are relevant for all biology research, along with special considerations for projects using -omics approaches”👇🏼

#Perspective in @natcomms.nature.com

Manuel Kleiner @manuelkleiner.bsky.social · Aug 7

I am really excited to see this article on basic experimental design principles published. Definitely will be mandatory reading for incoming graduate students in my lab. Maggie Wagner who led this article did an amazing job with the illustrations of basic principles www.nature.com/articles/s41...

How thoughtful experimental design can empower biologists in the omics era - Nature Communications

Here, the authors discuss principles of experimental design that are relevant for all biology research, along with special considerations for projects using -omics approaches, highlighting common expe...

www.nature.com

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chasingmicrobes @chasingmicrobes.bsky.social · Aug 1

Bring an N95 or KN95 mask if you are headed to ASP this weekend and have asthma/sensitive lungs. The midwest is smothered in smoke from the Canadian wildfires right now.

woody and buzz lightyear from toy story are standing next to each other with the caption smoke everywhere

ALT: woody and buzz lightyear from toy story are standing next to each other with the caption smoke everywhere

media.tenor.com

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Dan Udwary @danudwary.secondarymetabolism.com · Jul 16

Here's a fun perspective piece on Cyanobacteria as prolific natural product producers with great potential for drug discovery. Thanks especially to @philmuslab.bsky.social for ringleading and letting us contribute!
pubs.rsc.org/en/content/a...

Green genes from blue greens: challenges and solutions to unlocking the potential of cyanobacteria in drug discovery

Cyanobacteria are prolific producers of biologically active compounds that are important in influencing ecology, behavior of interacting organisms, and as leads in drug discovery efforts. Here we disc...

pubs.rsc.org

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Philmus Lab @ OSU @philmuslab.bsky.social · Jul 16

Come read about our thoughts on why cyanobacteria are underrepresented in drug discovery and how both synthetic biology and native hosts can help.
This was fun to work on with a great group of people who include @dtdoering.bsky.social @danudwary.secondarymetabolism.com @eustaquiolab.bsky.social

Dan Udwary @danudwary.secondarymetabolism.com · Jul 16

Here's a fun perspective piece on Cyanobacteria as prolific natural product producers with great potential for drug discovery. Thanks especially to @philmuslab.bsky.social for ringleading and letting us contribute!
pubs.rsc.org/en/content/a...

Green genes from blue greens: challenges and solutions to unlocking the potential of cyanobacteria in drug discovery

Cyanobacteria are prolific producers of biologically active compounds that are important in influencing ecology, behavior of interacting organisms, and as leads in drug discovery efforts. Here we disc...

pubs.rsc.org

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Eustaquio Lab @eustaquiolab.bsky.social · Jul 2

Congratulations Shaun!

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ᐯIᑕTOᖇ ᑎIᘔET, ᗰᗪ @nizet.bsky.social · Apr 23

Pleased to share our new paper out in 𝘑𝘰𝘶𝘳𝘯𝘢𝘭 𝘰𝘧 𝘊𝘭𝘪𝘯𝘪𝘤𝘢𝘭 𝘐𝘯𝘷𝘦𝘴𝘵𝘪𝘨𝘢𝘵𝘪𝘰𝘯 led by Monika Kumaraswamy, MD, now Chief of Infectious Diseases UTexas-Tyler

Is minimimum inhibitory concentration (MIC) testing the gold standard for antibiotic-resistant superbugs? 🦠 🧫

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www.jci.org/articles/vie...

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Natural Product Reports @natprodreports.rsc.org · Apr 3

🔓Check out this #OpenAccess review by Lindsay Caesar & co. at @unm.edu & James Madison University, part of our Emerging Investigators collection, on natural product discovery from microbial communities in caves & underground mines #natprod #microsky

Read in full here🔽

Subterranean marvels: microbial communities in caves and underground mines and their promise for natural product discovery

Covering: 2014 to 2024 Since the dawn of human history, caves have played an intimate role in our existence. From our earliest ancestors seeking shelter from the elements to more recent generations…

pubs.rsc.org

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Sherry Pagoto, PhD @drsherrypagoto.bsky.social · Mar 12

New report shows that NIH grants fueled $95 billion in economic activity and 407,782 jobs in 2024.

That's not to mention the countless lives that biomedical research has saved.

Show me a better investment than that.
www.forbes.com/sites/michae...

NIH Grants Fueled $95 Billion In FY 2024 Economic Activity, Finds New Report

National Institutes of Health grants generated almost $95 billion in economic activity nationwide in FY 2024 according to a new report by United for Medical Research.

www.forbes.com

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Natural Product Reports @natprodreports.rsc.org · Mar 3

🎉Natural Product Reports was delighted to announce last month that @ntiekfidele.bsky.social is the winner of the 2025 Natural Product Reports Emerging Investigator Lectureship!

Read more about Fidele and his research here🔽
blogs.rsc.org/np/2025/02/0...

#NatProd #ChemSky #PlantScience

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Marc Chevrette @wildtypemc.bsky.social · Feb 21

Out today in Angewandte Chemie

Evolution-Guided Discovery of Antimycobacterial Triculamin-Like Lasso Peptides

doi.org/10.1002/anie...

Fun collaboration with the Tørring lab

@thomastorring.bsky.social @tizianasvenningsen.bsky.social @amerrild.bsky.social

Evolution‐Guided Discovery of Antimycobacterial Triculamin‐Like Lasso Peptides

Triculamin is a ribosomally synthesized and post-translationally modified peptide (RiPP) lasso peptide with potent antimycobacterial activity, produced by an unusual, non-canonical biosynthetic gene ...

doi.org

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Eustaquio Lab @eustaquiolab.bsky.social · Feb 22

It’s so nice to see our Burkholderia host being successfully used to discover new natural products!

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Eustaquio Lab @eustaquiolab.bsky.social · Feb 20

Drug discovery requires basic research.
Pharma relies on basic research carried out in academia.
How can pharma CEOs remain quiet or worse yet, support the onslaught on basic research?
It is short sighted to say the least!

www.science.org/content/blog...

Pharma CEOS Speaking Up, Damn It

www.science.org

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Ellis Crawford @elliscrawford.bsky.social · Feb 11

First direct chemical synthesis of a gene over 1700 nucleotides long covered by @chemistryworld.com!

Read the full paper in Chemical Science (which is free to read!) here:

pubs.rsc.org/en/content/a...

#ChemSky 🧪 #ChemBio

First direct chemical synthesis of a gene over 1700 nucleotides long

Innovative use of non-porous solid supports allows synthesis of very long oligonucleotides

www.chemistryworld.com

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Joshua Weitz @joshuasweitz.bsky.social · Feb 6

NIGMS council meeting has been postponed.

This will reverberate.

America's scientific leadership and its innovation economy is under threat.

www.nigms.nih.gov/about/counci...

NIGMS council meeting for 2/6/25 postponed

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Andrew Singer @oxonandrew.bsky.social · Feb 5

The overview of AMR that you always wanted (someone else to write) - amazing!

Truly brilliant paper with great figures! @lancetmicrobe.bsky.social

www.thelancet.com/journals/lan...

Antimicrobial resistance: a concise update

Antimicrobial resistance (AMR) is a serious threat to global public health, with approximately 5 million deaths associated with bacterial AMR in 2019. Tackling AMR requires a multifaceted and cohesive...

www.thelancet.com

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Derek Lowe @dereklowe.bsky.social · Feb 4

A long post about what’s happening to the science funding agencies in the US and why. As mentioned, this one just kept getting longer even as I kept stripping curse words from it.

www.science.org/content/blog...

What's Happening Inside the NIH and NSF

www.science.org

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Grace Thoburn @gracethoburn.bsky.social · Feb 4

We're delighted to announce Fidele Ntie-Kang (University of Buea) as the winner of the 2025 Natural Product Reports Emerging Investigator Lectureship! 🎉 Read more about Fidele and his research here: blogs.rsc.org/np/2025/02/0...

#NatProd #PlantScience

Graphic announcing Fidele Ntie-Kang as the Lectureship winner.

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Dr Katherine Duncan @kateduncan.bsky.social · Jan 9

www.washingtonpost.com/lifestyle/20... brilliant to see this from Brian Murphy’s lab and their exemplary outreach work

Camarria is already looking forward to her future career.
“I want to be a scientist,” she said.

And Camerria was an author on the published paper pubs.acs.org/doi/10.1021/...

Middle-schooler finds goose poop that has cancer-fighting compound

“My mom, auntie and grandma have all had cancer, so it makes me happy that something I found could help,” said Camarria Williams.

www.washingtonpost.com

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Katherine Maloney @katherinem.bsky.social · Jan 7

Strong showing of @scrippsocean.bsky.social and @ucsdhealthsci.bsky.social alums at the first full day of SIMB #NP2025 meeting @chekanlab.bsky.social
@eustaquiolab.bsky.social Neha Garg Kaity Ryan

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Eustaquio Lab @eustaquiolab.bsky.social · Dec 10

Interested in genome mining for natural product discovery? Check out our recent paper in collaboration with the Linington lab pubs.rsc.org/en/content/a...

Discovery of megapolipeptins by genome mining of a Burkholderiales bacteria collection

Burkholderiales bacteria have emerged as a promising source of structurally diverse natural products that are expected to play important ecological and industrial roles. This order ranks in the top th...

pubs.rsc.org

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Marnix Medema @marnixmedema.bsky.social · Dec 5

Come join us!!

Bas E. Dutilh @bedutilh.bsky.social · Dec 4

We have an opening for a 4-year postdoc position to study the #rhizosphere #microbiome in @utrechtuniversity.bsky.social @w-u-r.bsky.social, joint project with @marnixmedema.bsky.social in the context of MiCRop. Please tag/forward this to potential candidates and/or repost: www.uu.nl/en/organisat...

Bioinformatics Postdoc at UU/WUR: Map Metabolic Interactions in the Rhizosphere

Contribute to plant health and our understanding of the metabolic interactions between microbes and plants in the rhizosphere by computational modelling!

www.uu.nl

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