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FEBS Letters
@febsletters.bsky.social
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Publishing cutting-edge reports in Biochemistry, Structural Biology, Molecular Cell Biology, Biophysics, Systems Biology, Microbiology and more. Part of @febspress.bsky.social. febsletters.org
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FEBS Letters @febsletters.bsky.social · 2d
🍂 Our second November issue is online now! Featuring...

🖊️ Reviews on the molecular bases of disease, including #CysticFibrosis
🦠 Editor's Choice: GES-1 inhibition by enmetazobactam and tazobactam
👩‍🔬 Two Scientists' Forum articles on #WomenInScience.

➡️ bit.ly/4ob8Xop

#antibioticresistance
febsletters.bsky.social
⚕️ Pediatric cancers are biologically distinct and challenging to model. This review explores how emerging #organoid systems are enabling patient-specific pediatric tumor models, advancing mechanisms and therapy testing in #PediatricOncology.

➡️ doi.org/10.1002/1873-3468.70188
November 26, 2025 at 12:00 PM
febsletters.bsky.social
⚡ How conserved is respiratory complex I (CI) across #eukaryotes — and where does #evolution leave its mark? This review by @lettsscience.bsky.social compares CI across seven lineages, revealing variation in core subunits and lineage-specific accessory proteins.

➡️ doi.org/10.1002/1873-3468.70181
November 25, 2025 at 7:38 PM
febsletters.bsky.social
🍂 Our second November issue is online now! Featuring...

🖊️ Reviews on the molecular bases of disease, including #CysticFibrosis
🦠 Editor's Choice: GES-1 inhibition by enmetazobactam and tazobactam
👩‍🔬 Two Scientists' Forum articles on #WomenInScience.

➡️ bit.ly/4ob8Xop

#antibioticresistance
November 24, 2025 at 5:43 PM
febsletters.bsky.social
🎉We congratulate🌟Abhishek Dubey🌟(Leibniz Institute on Aging–Fritz Lipmann Institute, Jena, Germany), on winning the FEBS Letters prize for the best short talk at the Aging and Microbiome Conference 2025, held in Jena, Germany! 👏👏👏🎊

@leibnizfli.bsky.social
November 20, 2025 at 1:06 PM
Reposted by FEBS Letters
danielbachurski.bsky.social
Our illustration of immune cell-derived #extracellularvesicles (EVs) in B-cell malignancies is on the cover of FEBS Letters' "Biology of B-cell Malignancies".

We discuss how novel techniques enhance understanding of cell communication in the tumor-immune environment. doi.org/10.1002/1873...
November 1, 2025 at 7:28 PM
febsletters.bsky.social
New graphical review out now from our Biology of B-cell Malignancies special issue

📕 Biological and technical complexities in analyzing extracellular vesicle immune interactions in B-cell malignancies

✍️ @danielbachurski.bsky.social & Michael Hallek

🔗 febs.onlinelibrary.wiley.com/doi/10.1002/...
November 19, 2025 at 9:45 AM
febsletters.bsky.social
📕 A reminder that our Biology of B-cell malignancies special issue is out now!

This special issue focuses on recent conceptual and technological advancements that have refined our understanding of B-cell neoplasms.

Discover the special issue, here ➡️ febs.onlinelibrary.wiley.com/toc/18733468...
November 17, 2025 at 3:48 PM
febsletters.bsky.social
🎉🏅We congratulate 🌟Zeynep Dokuzluoglu🌟 (German Center for #Neurodegenerative Diseases, #DZNE, Dresden) on winning the FEBS Letters #PosterPrize at the EMBO/EMBL Symposium on #organoids, held in Heidelberg, Germany!

#EESOrgan

@events.embl.org
November 13, 2025 at 12:17 PM
febsletters.bsky.social
“Influencing science and influencing scientists are two distinct, and distinctly difficult, achievements. Professor Jean H. Langenheim accomplished both.” 🌿

🏆 FEBS Letters presents an essay by Rayane da Cruz Albino, winner of our #WomenInScience Writing Contest:

➡️ doi.org/10.1002/1873-3468.70197
November 11, 2025 at 12:02 PM
Reposted by FEBS Letters
thevilchezlab.bsky.social
Saygin’s new ALS paper — showing nucleoporin alterations — just made the journal front cover @febsletters.bsky.social febs.onlinelibrary.wiley.com/doi/10.1002/...
febs.onlinelibrary.wiley.com/doi/10.1002/...
FEBS Press
Cover illustration Stress granules in iPSCs treated with arsenite (G3BP1 (green) / NUP107 (red) / Hoechst (nucleus)). Image credit: Saygin Bilican. The image refers to Bilican et al., “C9orf72 ALS-ca....
febs.onlinelibrary.wiley.com
November 10, 2025 at 7:29 PM
Reposted by FEBS Letters
ru5762proteostasis.bsky.social
🚨Exciting news: A recent study from our #FOR5762 member @thevilchezlab.bsky.social has been selected for the cover of @febsletters.bsky.social!

Huge congrats to @thevilchezlab.bsky.social, Saygın Bilican and all co-authors for this fantastic highlight on #ALS-linked #Nup107 mislocalization! 🎉
November 11, 2025 at 8:00 AM
febsletters.bsky.social
🍂 Our November issue is here!

🧬 Editor's Choice: C9orf72-#ALS mutations lead to Nup107 aggregation
👩‍🔬 Scientists' Forum Presenting the winner of our #WomenInScience writing contest

Find the whole issue, featuring research articles on #neuroscience and #cancer, here:

➡️ bit.ly/3JGZG9q
November 10, 2025 at 7:11 PM
febsletters.bsky.social
Tropomodulin-1 caps the slow-growing ends of #actin filaments, controlling their length and stability to maintain cellular architecture. Discover how TMOD1 is emerging as a multifunctional protein connecting cytoskeletal dynamics to disease and #DrugDiscovery here:

➡️ doi.org/10.1002/1873-3468.70176
November 6, 2025 at 12:02 PM
febsletters.bsky.social
The TOR pathway is a master regulator of cell growth and #metabolism. Here, Robbie Loewith and Lucas Tafur revisit the #StructuralBiology of TOR Complexes 1 and 2, highlighting how lipid #membranes serve as platforms for their activation and regulation.

➡️ doi.org/10.1002/1873-3468.70171
November 4, 2025 at 12:01 PM
febsletters.bsky.social
🦠 Enteropathogenic #Ecoli (#EPEC) attaches to host intestinal epithelial cells. Compared to HeLa cells, jejunal #organoid-derived monolayers show lower bacterial attachment, less epithelial cell death and delayed inflammatory response:

➡️ doi.org/10.1002/1873-3468.70182
October 31, 2025 at 12:02 PM
febsletters.bsky.social
🔔 Special Issue: Biology of B-cell malignancies

Seven Reviews focusing on conceptual and technological advancements in our understanding of B-cell neoplasms illustrate how they secure survival and evade therapy ➡️ bit.ly/48UhckL

👩‍🔬 Guest-edited by Patricia Pérez-Galán & Martina Seiffert
October 30, 2025 at 5:05 PM
febsletters.bsky.social
🎉🎖️Congratulations to 🌟Gabriel Péréz-Lara🌟 (UNAB, Santiago, Chile), winner of the FEBS Letters #PosterPrize at #MBioSys25, held in Puerto Varas, Chile! 🎉👏👏👏🎊

@molbiosystems.bsky.social
October 30, 2025 at 1:24 PM
febsletters.bsky.social
🎉🎖️We congratulate 🌟Francesca Cervellini 🌟 @tigem.bsky.social on winning the FEBS Letters #PosterPrize at the #EMBO Workshop on #LipidDroplets, held in Sant Feliu de Guíxols, Spain! 🎉👏👏👏

#EMBOlipidDroplets
October 30, 2025 at 1:14 PM
febsletters.bsky.social
#CryoEM can now deliver atomic-resolution structures, but their value depends on the quality of their models.

This review highlights how combining traditional model-building with physics-based methods can shape the future of structural biology:

➡️ doi.org/10.1002/1873-3468.70165
October 29, 2025 at 12:04 PM
febsletters.bsky.social
Mice and pigs have taught us a lot about immunity, but #zebrafish models remain underused in this field. 🐟

Learn more about how recent advances on understudied gut #immune cells in zebrafish are helping us uncover immune mechanisms across vertebrates:

➡️ doi.org/10.1002/1873-3468.70161
October 27, 2025 at 12:04 PM
febsletters.bsky.social
🌍 “Together we can!”

Our latest #PatientAdvocacy interview is with the #MarfanEuropeNetwork, an organization of 14 national #MarfanSyndrome patient groups. Learn how they bring communities together here:

➡️ doi.org/10.1002/1873-3468.70183
October 24, 2025 at 11:03 AM
febsletters.bsky.social
🧬 Central to pseudouridylation of cellular #RNAs is dyskerin, a pseudouridine synthase with two known isoforms.

While the nuclear isoform is well studied, the cytoplasmic one is less explored. Here, Angrisani and Furia propose a model for its potential roles:

➡️ doi.org/10.1002/1873-3468.70154
October 22, 2025 at 11:03 AM
febsletters.bsky.social
We're hiring for an Editorial Assistant!

📅 Deadline: 15 November 2025
📩 Send your CV and cover letter explaining your interest in the role to Daniela Ruffell: [email protected]

Find the full job description here ➡️ www.febs.org/news/jobs-po...
October 21, 2025 at 12:14 PM
febsletters.bsky.social
👩‍🔬 In the UK, women represent just 26.7% of the #STEM workforce. For FEBS Letters, Dr. Laura Norton discusses the need for positive action.

Demand for STEM workers keeps growing and there is still a long way to go before we achieve true equity.

➡️ doi.org/10.1002/1873-3468.70178

#WomenInScience
October 20, 2025 at 11:02 AM
febsletters.bsky.social
🔔 Our new issue features perspectives on the origins of life & #amyloid, and research on #StructuralBiology & #ProteinChemistry:

🌍 #AmyloidWorld hypothesis of the #OriginOfLife
🧬 Emergence of #evolution in the #RNA world
🧑‍🔬 Scientists' Forum: Cultivating female talent in science

➡️ bit.ly/4ojAbcM
October 17, 2025 at 12:05 PM