FEBS Letters
@febsletters.bsky.social
Publishing cutting-edge reports in Biochemistry, Structural Biology, Molecular Cell Biology, Biophysics, Systems Biology, Microbiology and more. Part of @febspress.bsky.social. febsletters.org
Pinned
👩🔬Wishing everyone a happy International Day of Women and Girls in Science! #WomenInScience #EveryVoiceInScience
🔍Check out the collection linked below, which showcases articles reflecting on the issues and triumphs of women in their fields — plus some excerpts, featuring women in their own words.
🔍Check out the collection linked below, which showcases articles reflecting on the issues and triumphs of women in their fields — plus some excerpts, featuring women in their own words.
Collaboration is the backbone of modern science – but seldom runs smoothly. In our latest The Scientists’ Forum article, Muhammad Naseem looks at the barriers to effective #collaborations as well as potential personal and institutional solutions. 🤝🔬🦠
#science #lifescience
doi.org/10.1002/1873...
#science #lifescience
doi.org/10.1002/1873...
February 13, 2026 at 9:43 AM
Collaboration is the backbone of modern science – but seldom runs smoothly. In our latest The Scientists’ Forum article, Muhammad Naseem looks at the barriers to effective #collaborations as well as potential personal and institutional solutions. 🤝🔬🦠
#science #lifescience
doi.org/10.1002/1873...
#science #lifescience
doi.org/10.1002/1873...
👩🔬Wishing everyone a happy International Day of Women and Girls in Science! #WomenInScience #EveryVoiceInScience
🔍Check out the collection linked below, which showcases articles reflecting on the issues and triumphs of women in their fields — plus some excerpts, featuring women in their own words.
🔍Check out the collection linked below, which showcases articles reflecting on the issues and triumphs of women in their fields — plus some excerpts, featuring women in their own words.
February 11, 2026 at 4:13 PM
👩🔬Wishing everyone a happy International Day of Women and Girls in Science! #WomenInScience #EveryVoiceInScience
🔍Check out the collection linked below, which showcases articles reflecting on the issues and triumphs of women in their fields — plus some excerpts, featuring women in their own words.
🔍Check out the collection linked below, which showcases articles reflecting on the issues and triumphs of women in their fields — plus some excerpts, featuring women in their own words.
The #GTPase #Npa3 plays a key role in RNA Pol II assembly & nuclear import. In a new study, Martín Mora-García et al. reveal crosstalk between Npa3 and #TORC1 signalling, suggesting involvement in translation initiation, TORC1 signaling, and #stress adaptation🧬
Read it here: tinyurl.com/bdau2mp2
Read it here: tinyurl.com/bdau2mp2
February 11, 2026 at 1:02 PM
The #GTPase #Npa3 plays a key role in RNA Pol II assembly & nuclear import. In a new study, Martín Mora-García et al. reveal crosstalk between Npa3 and #TORC1 signalling, suggesting involvement in translation initiation, TORC1 signaling, and #stress adaptation🧬
Read it here: tinyurl.com/bdau2mp2
Read it here: tinyurl.com/bdau2mp2
☀️🌔How do mammalian cells align their internal clocks with the outside world? This review explores how light, feeding and temperature entrain cellular #CircadianRhythms, and why understanding the molecular mechanisms behind cellular timing matters for our #Health. doi.org/10.1002/1873...
February 10, 2026 at 1:02 PM
☀️🌔How do mammalian cells align their internal clocks with the outside world? This review explores how light, feeding and temperature entrain cellular #CircadianRhythms, and why understanding the molecular mechanisms behind cellular timing matters for our #Health. doi.org/10.1002/1873...
🔔 Issue 3 of 2026 is live! Featuring:
🧫 Review: #Helicobacterpylori pathogenesis
🦠 In a Nutshell: Universal stress proteins in #mycobacteria
👨🔬: Highlights from the Susan Lindquist School on #Proteostasis
🔬 Research on #enzymology, structural #biology, and gene expression
▶️ tinyurl.com/3yxe4t9b
🧫 Review: #Helicobacterpylori pathogenesis
🦠 In a Nutshell: Universal stress proteins in #mycobacteria
👨🔬: Highlights from the Susan Lindquist School on #Proteostasis
🔬 Research on #enzymology, structural #biology, and gene expression
▶️ tinyurl.com/3yxe4t9b
February 9, 2026 at 2:23 PM
🔔 Issue 3 of 2026 is live! Featuring:
🧫 Review: #Helicobacterpylori pathogenesis
🦠 In a Nutshell: Universal stress proteins in #mycobacteria
👨🔬: Highlights from the Susan Lindquist School on #Proteostasis
🔬 Research on #enzymology, structural #biology, and gene expression
▶️ tinyurl.com/3yxe4t9b
🧫 Review: #Helicobacterpylori pathogenesis
🦠 In a Nutshell: Universal stress proteins in #mycobacteria
👨🔬: Highlights from the Susan Lindquist School on #Proteostasis
🔬 Research on #enzymology, structural #biology, and gene expression
▶️ tinyurl.com/3yxe4t9b
Skin wound healing depends on more than structure alone. 🩸This review explores how matricellular proteins fine-tune #ExtracellularMatrix signalling to coordinate cell migration, proliferation and tissue repair, highlighting their central role in #RegenerativeMedicine. doi.org/10.1002/1873...
February 5, 2026 at 1:03 PM
Skin wound healing depends on more than structure alone. 🩸This review explores how matricellular proteins fine-tune #ExtracellularMatrix signalling to coordinate cell migration, proliferation and tissue repair, highlighting their central role in #RegenerativeMedicine. doi.org/10.1002/1873...
The Dot/Icm type IV secretion system (#T4SS) is essential for #Legionella pneumophila infection, but the mechanism remains incompletely understood. In a new study, Dutka (@przemekdut.bsky.social) et al. provide insight into the molecular organization of T4SS. #Legionnaires🔎🔬
doi.org/10.1002/1873...
doi.org/10.1002/1873...
February 4, 2026 at 1:01 PM
The Dot/Icm type IV secretion system (#T4SS) is essential for #Legionella pneumophila infection, but the mechanism remains incompletely understood. In a new study, Dutka (@przemekdut.bsky.social) et al. provide insight into the molecular organization of T4SS. #Legionnaires🔎🔬
doi.org/10.1002/1873...
doi.org/10.1002/1873...
💊 Phosphatidylinositol 4-kinases are central regulators of cellular signaling and membrane trafficking, yet are frequently hijacked by pathogens. This review discusses their dual roles and evaluates their potential as #DrugTargets for #InfectiousDiseases. 🦠 doi.org/10.1002/1873...
February 2, 2026 at 1:02 PM
💊 Phosphatidylinositol 4-kinases are central regulators of cellular signaling and membrane trafficking, yet are frequently hijacked by pathogens. This review discusses their dual roles and evaluates their potential as #DrugTargets for #InfectiousDiseases. 🦠 doi.org/10.1002/1873...
What do extrachromosomal DNAs and excised signal circles have in common?⭕
This review highlights how both promote genome instability, pointing to potential #CancerVulnerabilities for #DrugDiscovery in #PrecisionOncology. doi.org/10.1002/1873...
This review highlights how both promote genome instability, pointing to potential #CancerVulnerabilities for #DrugDiscovery in #PrecisionOncology. doi.org/10.1002/1873...
January 29, 2026 at 1:02 PM
What do extrachromosomal DNAs and excised signal circles have in common?⭕
This review highlights how both promote genome instability, pointing to potential #CancerVulnerabilities for #DrugDiscovery in #PrecisionOncology. doi.org/10.1002/1873...
This review highlights how both promote genome instability, pointing to potential #CancerVulnerabilities for #DrugDiscovery in #PrecisionOncology. doi.org/10.1002/1873...
The published meeting report from the Susan Lindquist School on Proteostasis captures four days of vibrant science, #Collaboration, and #Community — where diverse voices crossed generations and cultures to shape the future of #ProteostasisResearch. doi.org/10.1002/1873...
January 27, 2026 at 1:01 PM
The published meeting report from the Susan Lindquist School on Proteostasis captures four days of vibrant science, #Collaboration, and #Community — where diverse voices crossed generations and cultures to shape the future of #ProteostasisResearch. doi.org/10.1002/1873...
🔔 Issue 2 of 2026 is live! 🎉 Featuring:
🧑🔬 Scientists' Forum: Mothers in academia
🖊️ Review: #Fibroblasts in cancer metabolism
☀️ Review: Red-light #photosynthesis in eukaryotes
🦠 Research on #cancer biology and #microbiology
▶️ bit.ly/4ae2pRX
🧑🔬 Scientists' Forum: Mothers in academia
🖊️ Review: #Fibroblasts in cancer metabolism
☀️ Review: Red-light #photosynthesis in eukaryotes
🦠 Research on #cancer biology and #microbiology
▶️ bit.ly/4ae2pRX
January 26, 2026 at 2:56 PM
🔔 Issue 2 of 2026 is live! 🎉 Featuring:
🧑🔬 Scientists' Forum: Mothers in academia
🖊️ Review: #Fibroblasts in cancer metabolism
☀️ Review: Red-light #photosynthesis in eukaryotes
🦠 Research on #cancer biology and #microbiology
▶️ bit.ly/4ae2pRX
🧑🔬 Scientists' Forum: Mothers in academia
🖊️ Review: #Fibroblasts in cancer metabolism
☀️ Review: Red-light #photosynthesis in eukaryotes
🦠 Research on #cancer biology and #microbiology
▶️ bit.ly/4ae2pRX
How do cells keep time? 🕰️ This review explores #CircadianRhythms at the molecular level, showing how #ComputationalModeling reveals clock protein structure and dynamics—and why integrating methods is key to understanding biological time across life. doi.org/10.1002/1873...
January 22, 2026 at 1:01 PM
How do cells keep time? 🕰️ This review explores #CircadianRhythms at the molecular level, showing how #ComputationalModeling reveals clock protein structure and dynamics—and why integrating methods is key to understanding biological time across life. doi.org/10.1002/1873...
Disordered, but rhythmic: Intrinsically disordered protein regions (#IDRs) play a key role in the #circadian clock. 🕙🌀 In a timely (ahem) Review, Emery Usher & Jacqueline Pelham (@pelhamjackie.bsky.social) discuss the role of IDRs in clock proteins.
#IDP #IDR Read here: shorturl.at/QsTaa
#IDP #IDR Read here: shorturl.at/QsTaa
January 19, 2026 at 1:01 PM
Disordered, but rhythmic: Intrinsically disordered protein regions (#IDRs) play a key role in the #circadian clock. 🕙🌀 In a timely (ahem) Review, Emery Usher & Jacqueline Pelham (@pelhamjackie.bsky.social) discuss the role of IDRs in clock proteins.
#IDP #IDR Read here: shorturl.at/QsTaa
#IDP #IDR Read here: shorturl.at/QsTaa
How does the #circadian clock influence the outcome of #bacterial #infections? 🕐🦠A new Review by Devons Mo, Catherine S. Palmer, & Jacqueline M. Kimmey (@jkimmey.bs ky.social) discusses this question for 3 #pathogens: S. enterica, L. monocytogenes, and S. pneumoniae. Read here: shorturl.at/csWft
January 16, 2026 at 1:00 PM
How does the #circadian clock influence the outcome of #bacterial #infections? 🕐🦠A new Review by Devons Mo, Catherine S. Palmer, & Jacqueline M. Kimmey (@jkimmey.bs ky.social) discusses this question for 3 #pathogens: S. enterica, L. monocytogenes, and S. pneumoniae. Read here: shorturl.at/csWft
👩🔬 #Parenthood has negative effects on the academic careers of women, but not men. For the Scientists' Forum, Devanshi Agarwal & Sonya E. Neal interviewed mothers at various career stages in biology on challenges & strategies for success:
➡️ doi.org/10.1002/1873-3468.70262
@neal-lab.bsky.social
➡️ doi.org/10.1002/1873-3468.70262
@neal-lab.bsky.social
January 15, 2026 at 12:02 PM
👩🔬 #Parenthood has negative effects on the academic careers of women, but not men. For the Scientists' Forum, Devanshi Agarwal & Sonya E. Neal interviewed mothers at various career stages in biology on challenges & strategies for success:
➡️ doi.org/10.1002/1873-3468.70262
@neal-lab.bsky.social
➡️ doi.org/10.1002/1873-3468.70262
@neal-lab.bsky.social
⏰ #Circadian rhythms in intracellular #magnesium concentrations were recently discovered in multiple eukaryotes. Helen K. Feord & @vanooijenlab.bsky.social propose a reciprocal feedback model between rhythmic usage of Mg2+ and rhythmic transport activity:
➡️ doi.org/10.1002/1873-3468.70228
➡️ doi.org/10.1002/1873-3468.70228
January 13, 2026 at 12:02 PM
⏰ #Circadian rhythms in intracellular #magnesium concentrations were recently discovered in multiple eukaryotes. Helen K. Feord & @vanooijenlab.bsky.social propose a reciprocal feedback model between rhythmic usage of Mg2+ and rhythmic transport activity:
➡️ doi.org/10.1002/1873-3468.70228
➡️ doi.org/10.1002/1873-3468.70228
🔔 Our first issue of 2026 is live! 🎉 Featuring:
🧑🔬 Scientists' Forum: Supervising #postdoc students
📋 In a Nutshell: Topomodulin 1
🫧 Research on #Membranes, #Cytoskeleton, and #MitochondrialBiology
▶️ bit.ly/4pDKfxw
🧑🔬 Scientists' Forum: Supervising #postdoc students
📋 In a Nutshell: Topomodulin 1
🫧 Research on #Membranes, #Cytoskeleton, and #MitochondrialBiology
▶️ bit.ly/4pDKfxw
January 12, 2026 at 4:04 PM
🔔 Our first issue of 2026 is live! 🎉 Featuring:
🧑🔬 Scientists' Forum: Supervising #postdoc students
📋 In a Nutshell: Topomodulin 1
🫧 Research on #Membranes, #Cytoskeleton, and #MitochondrialBiology
▶️ bit.ly/4pDKfxw
🧑🔬 Scientists' Forum: Supervising #postdoc students
📋 In a Nutshell: Topomodulin 1
🫧 Research on #Membranes, #Cytoskeleton, and #MitochondrialBiology
▶️ bit.ly/4pDKfxw
In #diabetes, #endothelial cells are sensitive to changes in blood glucose. Bushell et al. show DHLA supplementation enhances H2S production via 3-MST & improves endothelial function under high glucose conditions, with implications for diabetes treatment.
➡️ doi.org/10.1002/1873-3468.70239
➡️ doi.org/10.1002/1873-3468.70239
January 9, 2026 at 12:01 PM
In #diabetes, #endothelial cells are sensitive to changes in blood glucose. Bushell et al. show DHLA supplementation enhances H2S production via 3-MST & improves endothelial function under high glucose conditions, with implications for diabetes treatment.
➡️ doi.org/10.1002/1873-3468.70239
➡️ doi.org/10.1002/1873-3468.70239
⌛ Increases in human life expectancy are not matched by increased health in old age. In a new review in FEBS Letters, @jetteleng.bsky.social et al. explore research on #hematopoieticstemcell rejuvenation in #ageing.
➡️ doi.org/10.1002/1873-3468.70215
➡️ doi.org/10.1002/1873-3468.70215
January 8, 2026 at 12:01 PM
⌛ Increases in human life expectancy are not matched by increased health in old age. In a new review in FEBS Letters, @jetteleng.bsky.social et al. explore research on #hematopoieticstemcell rejuvenation in #ageing.
➡️ doi.org/10.1002/1873-3468.70215
➡️ doi.org/10.1002/1873-3468.70215
🧪 New method alert! Hannes Mutschler et al. describe FLARE, a new single-tube, real-time assay for monitoring of ribonucleotide reductase activity. Read the OA article for free here:
➡️ doi.org/10.1002/1873-3468.70237
#RAR #ribonucleotidereductase #methods #DNA #ribonucleotide
➡️ doi.org/10.1002/1873-3468.70237
#RAR #ribonucleotidereductase #methods #DNA #ribonucleotide
January 7, 2026 at 12:01 PM
🧪 New method alert! Hannes Mutschler et al. describe FLARE, a new single-tube, real-time assay for monitoring of ribonucleotide reductase activity. Read the OA article for free here:
➡️ doi.org/10.1002/1873-3468.70237
#RAR #ribonucleotidereductase #methods #DNA #ribonucleotide
➡️ doi.org/10.1002/1873-3468.70237
#RAR #ribonucleotidereductase #methods #DNA #ribonucleotide
🫧 #Phosphoinositides play an essential role in #membrane biology, influencing stress response, membrane remodelling, endosomal trafficking, and more. Read about the latest advances in a new review by Carla Alemany and Etienne Morel:
➡️ doi.org/10.1002/1873-3468.70213
@membramics-lab.bsky.social
➡️ doi.org/10.1002/1873-3468.70213
@membramics-lab.bsky.social
January 6, 2026 at 12:01 PM
🫧 #Phosphoinositides play an essential role in #membrane biology, influencing stress response, membrane remodelling, endosomal trafficking, and more. Read about the latest advances in a new review by Carla Alemany and Etienne Morel:
➡️ doi.org/10.1002/1873-3468.70213
@membramics-lab.bsky.social
➡️ doi.org/10.1002/1873-3468.70213
@membramics-lab.bsky.social
🔔 FEBS Letters' final issue of 2025 features:
🖊️ Reviews covering circulating endothelial cells, synthetic #CellMembranes, & lipidated cargo trafficking
👩🔬 Scientists' Forum articles including a deep-dive on the #GraphicalAbstract
🧬 Research on #DNA damage & more...
➡️ bit.ly/4jpcfUf
🖊️ Reviews covering circulating endothelial cells, synthetic #CellMembranes, & lipidated cargo trafficking
👩🔬 Scientists' Forum articles including a deep-dive on the #GraphicalAbstract
🧬 Research on #DNA damage & more...
➡️ bit.ly/4jpcfUf
January 5, 2026 at 12:00 PM
🔔 FEBS Letters' final issue of 2025 features:
🖊️ Reviews covering circulating endothelial cells, synthetic #CellMembranes, & lipidated cargo trafficking
👩🔬 Scientists' Forum articles including a deep-dive on the #GraphicalAbstract
🧬 Research on #DNA damage & more...
➡️ bit.ly/4jpcfUf
🖊️ Reviews covering circulating endothelial cells, synthetic #CellMembranes, & lipidated cargo trafficking
👩🔬 Scientists' Forum articles including a deep-dive on the #GraphicalAbstract
🧬 Research on #DNA damage & more...
➡️ bit.ly/4jpcfUf
🎊 The FEBS Letters team thanks all our authors, reviewers, editors, and readers for our success in 2025! 🎊
We look forward to bringing you more fast publishing for curious scientists in the new year!
We look forward to bringing you more fast publishing for curious scientists in the new year!
December 31, 2025 at 12:03 PM
🎊 The FEBS Letters team thanks all our authors, reviewers, editors, and readers for our success in 2025! 🎊
We look forward to bringing you more fast publishing for curious scientists in the new year!
We look forward to bringing you more fast publishing for curious scientists in the new year!
The #DPPIV family #proteases were thought to function just as dipeptidyl #peptidases, cleaving only after proline or alanine. Here, Trivedi and Gudipati report that C. elegans DPF-3 and human DPP4 possess previously unrecognized tripeptidyl peptidase activity.
➡️ doi.org/10.1002/1873-3468.70219
➡️ doi.org/10.1002/1873-3468.70219
December 30, 2025 at 12:02 PM
The #DPPIV family #proteases were thought to function just as dipeptidyl #peptidases, cleaving only after proline or alanine. Here, Trivedi and Gudipati report that C. elegans DPF-3 and human DPP4 possess previously unrecognized tripeptidyl peptidase activity.
➡️ doi.org/10.1002/1873-3468.70219
➡️ doi.org/10.1002/1873-3468.70219
🧑🏫 Postdocs often supervise students, and even though it helps them build #LeadershipSkills needed for future roles, many find this task a burden. This article offers tips to align expectations, build trust, and turn #Mentorship to a driver for better science.
➡️ doi.org/10.1002/1873-3468.70214
➡️ doi.org/10.1002/1873-3468.70214
December 29, 2025 at 12:01 PM
🧑🏫 Postdocs often supervise students, and even though it helps them build #LeadershipSkills needed for future roles, many find this task a burden. This article offers tips to align expectations, build trust, and turn #Mentorship to a driver for better science.
➡️ doi.org/10.1002/1873-3468.70214
➡️ doi.org/10.1002/1873-3468.70214