The Fromm Lab
@frommlab.bsky.social
lab at @UiTNorgesarktis studying microRNAs, paleotranscriptomics, biosystematics with a fable for flatworms.
MirGeneDB, MirMachine, MirMiner (soon!)
MirGeneDB, MirMachine, MirMiner (soon!)
Pinned
The Fromm Lab
@frommlab.bsky.social
· Oct 21
a statue of a man 's head with a bunch of paper coming out of it
ALT: a statue of a man 's head with a bunch of paper coming out of it
media.tenor.com
🔥🔥🔥🔥New paper out; a opinion piece in @narjournal.bsky.social with Michael Hackenberg, @panosbino.bsky.social, Kevin K Peterson and @marcfriedlander.bsky.social 🔥🔥🔥🔥
„Knowing is not enough, we must apply“
academic.oup.com/nar/article/...
„Knowing is not enough, we must apply“
academic.oup.com/nar/article/...
#FREECOURSE-announcement
Want to learn about microRNA annotation and differential expression analyses? Within the Oslo Bioinformatics week 2025, we will be teaching a two-day course on the 9th and 10th of December at the University of Oslo. 1/2
Want to learn about microRNA annotation and differential expression analyses? Within the Oslo Bioinformatics week 2025, we will be teaching a two-day course on the 9th and 10th of December at the University of Oslo. 1/2
November 25, 2025 at 10:37 AM
#FREECOURSE-announcement
Want to learn about microRNA annotation and differential expression analyses? Within the Oslo Bioinformatics week 2025, we will be teaching a two-day course on the 9th and 10th of December at the University of Oslo. 1/2
Want to learn about microRNA annotation and differential expression analyses? Within the Oslo Bioinformatics week 2025, we will be teaching a two-day course on the 9th and 10th of December at the University of Oslo. 1/2
Reposted by The Fromm Lab
Latest work out today in @currentbiology.bsky.social
We find the fly development gene bicoid is much older than previously thought (~20 million yrs older!) 🪰🧬
To pinpoint its origins we tackled the Diptera phylogeny, providing some resolution (many open questions remain).
🔗 tinyurl.com/2vyuevpy
We find the fly development gene bicoid is much older than previously thought (~20 million yrs older!) 🪰🧬
To pinpoint its origins we tackled the Diptera phylogeny, providing some resolution (many open questions remain).
🔗 tinyurl.com/2vyuevpy
Revised evolutionary relationships within Brachycera and the early origin of bicoid in flies
Mulhair et al. uncover a functional bicoid in non-cyclorrhaphan flies, pushing the
gene's origin back by ∼20 million years. Reassessing the Diptera phylogeny using the
largest dataset to date permits ...
www.cell.com
October 17, 2025 at 3:14 PM
Latest work out today in @currentbiology.bsky.social
We find the fly development gene bicoid is much older than previously thought (~20 million yrs older!) 🪰🧬
To pinpoint its origins we tackled the Diptera phylogeny, providing some resolution (many open questions remain).
🔗 tinyurl.com/2vyuevpy
We find the fly development gene bicoid is much older than previously thought (~20 million yrs older!) 🪰🧬
To pinpoint its origins we tackled the Diptera phylogeny, providing some resolution (many open questions remain).
🔗 tinyurl.com/2vyuevpy
Reposted by The Fromm Lab
Out today, our take on 6-methyladenine #6mA evolution in Eukaryotes @natgenet.nature.com. We asked a simple question, is really DNA 6mA common across the eukaryotes? The answer is "yes" if you're a unicellular eukaryote 🦠, not so if you're multicellular 🐝🌱🍄. www.nature.com/articles/s41... 1/9
Adenine DNA methylation associated with transcriptionally permissive chromatin is widespread across eukaryotes - Nature Genetics
Long-read sequencing in 18 unicellular eukaryotes reveals that 6mA is widespread across eukaryotes and is enriched at transcriptionally permissive regions, which are also marked by H3K4me3.
www.nature.com
November 18, 2025 at 12:00 PM
Out today, our take on 6-methyladenine #6mA evolution in Eukaryotes @natgenet.nature.com. We asked a simple question, is really DNA 6mA common across the eukaryotes? The answer is "yes" if you're a unicellular eukaryote 🦠, not so if you're multicellular 🐝🌱🍄. www.nature.com/articles/s41... 1/9
Reposted by The Fromm Lab
Forty-thousand-year-old mammoth mummies yield oldest RNA yet found
Forty-thousand-year-old mammoth mummies yield oldest RNA yet found
Ancient RNA promises to shed light on how genes functioned in extinct animals
www.science.org
November 14, 2025 at 5:55 PM
Forty-thousand-year-old mammoth mummies yield oldest RNA yet found
Reposted by The Fromm Lab
The world’s oldest #RNA extracted from #WoollyMammoth: “gives us a completely different picture” ↓ 🧪⚒️
Woolly mammoth preserved in the Siberian permafrost for nearly 40,000 years sequenced. 🖥️ 🧬
www.youtube.com/watch?v=tHQv...
Weekend reading:
www.scilifelab.se/news/worlds-...
Woolly mammoth preserved in the Siberian permafrost for nearly 40,000 years sequenced. 🖥️ 🧬
www.youtube.com/watch?v=tHQv...
Weekend reading:
www.scilifelab.se/news/worlds-...
The world’s oldest #RNA extracted from #WoollyMammoth: “gives us a completely different picture”
YouTube video by SciLifeLab
www.youtube.com
November 14, 2025 at 4:11 PM
The world’s oldest #RNA extracted from #WoollyMammoth: “gives us a completely different picture” ↓ 🧪⚒️
Woolly mammoth preserved in the Siberian permafrost for nearly 40,000 years sequenced. 🖥️ 🧬
www.youtube.com/watch?v=tHQv...
Weekend reading:
www.scilifelab.se/news/worlds-...
Woolly mammoth preserved in the Siberian permafrost for nearly 40,000 years sequenced. 🖥️ 🧬
www.youtube.com/watch?v=tHQv...
Weekend reading:
www.scilifelab.se/news/worlds-...
Reposted by The Fromm Lab
RNA recovered from Siberian mammoth that died 39,000 years ago - https://www.channelnewsasia.com/business/rna-recovered-siberian-mammoth-died-39000-years-ago-5468461
RNA recovered from Siberian mammoth that died 39,000 years ago
WASHINGTON :Scientists have recovered the oldest-known RNA, a molecule necessary for most biological functions, from a woolly mammoth that inhabited Siberia about 39,000 years ago, showing it can last longer than previously known and promising a new path for studying organisms that lived long ago.The RNA, suc
www.channelnewsasia.com
November 14, 2025 at 4:10 PM
RNA recovered from Siberian mammoth that died 39,000 years ago - https://www.channelnewsasia.com/business/rna-recovered-siberian-mammoth-died-39000-years-ago-5468461
Reposted by The Fromm Lab
Woolly Mammoth Reveals the World’s Oldest RNA www.scientificamerican.com/article/wool...
A Frozen Woolly Mammoth Reveals the World’s Oldest RNA
RNA has been extracted from an ancient woolly mammoth, providing insight into its last moments on Earth
www.scientificamerican.com
November 14, 2025 at 5:58 PM
Woolly Mammoth Reveals the World’s Oldest RNA www.scientificamerican.com/article/wool...
Reposted by The Fromm Lab
Scientists pull ancient RNA from a wooly mammoth’s body : NPR
https://www.newsbeep.com/250103/
The body of the young wooly mammoth known as Yuka was so well-preserved that scientists were able to…
https://www.newsbeep.com/250103/
The body of the young wooly mammoth known as Yuka was so well-preserved that scientists were able to…
Scientists pull ancient RNA from a wooly mammoth's body : NPR - News Beep
Valerii V Plotnikov
www.newsbeep.com
November 14, 2025 at 5:55 PM
Scientists pull ancient RNA from a wooly mammoth’s body : NPR
https://www.newsbeep.com/250103/
The body of the young wooly mammoth known as Yuka was so well-preserved that scientists were able to…
https://www.newsbeep.com/250103/
The body of the young wooly mammoth known as Yuka was so well-preserved that scientists were able to…
Reposted by The Fromm Lab
40,000-year-old woolly mammoth RNA offers a peek into its last moments
Ancient RNA from Yuka, a 40,000-year-old woolly mammoth preserved in permafrost, can offer new biological insights into the Ice Age animal’s life.
Ancient RNA from Yuka, a 40,000-year-old woolly mammoth preserved in permafrost, can offer new biological insights into the Ice Age animal’s life.
40,000-year-old woolly mammoth RNA offers a peek into its last moments
Ancient RNA from Yuka, a 40,000-year-old woolly mammoth preserved in permafrost, can offer new biological insights into the Ice Age animal’s life.
animeaura.store
November 14, 2025 at 4:00 PM
40,000-year-old woolly mammoth RNA offers a peek into its last moments
Ancient RNA from Yuka, a 40,000-year-old woolly mammoth preserved in permafrost, can offer new biological insights into the Ice Age animal’s life.
Ancient RNA from Yuka, a 40,000-year-old woolly mammoth preserved in permafrost, can offer new biological insights into the Ice Age animal’s life.
We sequenced the oldest RNA (yet) ;-)
Yuka The Woolly Mammoth Just Gave Us The Oldest RNA Ever Sequenced. Via @sciencealert #Science 🔭🔬🧪🥼🧑🔬 #paleontology
Yuka The Woolly Mammoth Just Gave Us The Oldest RNA Ever Sequenced
A woolly mammoth that lived and died nearly 40,000 years ago has given us a spectacular scientific first, millennia later.
www.sciencealert.com
November 14, 2025 at 6:20 PM
We sequenced the oldest RNA (yet) ;-)
Reposted by The Fromm Lab
A young woolly mammoth now known as Yuka was frozen in the Siberian permafrost for about 40,000 years before it was discovered by local tusk hunters in 2010.
Now, a team has successfully sequenced Yuka’s RNA
—a feat many researchers once thought impossible.
Now, a team has successfully sequenced Yuka’s RNA
—a feat many researchers once thought impossible.
World’s oldest RNA extracted from ice age woolly mammoth
Sequencing an ancient creature’s RNA opens up a new window into extinct life.
arstechnica.com
November 14, 2025 at 6:13 PM
A young woolly mammoth now known as Yuka was frozen in the Siberian permafrost for about 40,000 years before it was discovered by local tusk hunters in 2010.
Now, a team has successfully sequenced Yuka’s RNA
—a feat many researchers once thought impossible.
Now, a team has successfully sequenced Yuka’s RNA
—a feat many researchers once thought impossible.
We dodo it: RNA from an extinct species 39k years old!!!
RNA molecules nearly 40,000 years old have been sequenced from woolly mammoth tissue, demonstrating that RNA can persist in permafrost and provide new insights into extinct species’ biology.
World's oldest RNA extracted from woolly mammoth
Researchers from Stockholm University have—for the first time ever—managed to successfully isolate and sequence RNA molecules from Ice Age woolly mammoths.
phys.org
November 14, 2025 at 6:19 PM
We dodo it: RNA from an extinct species 39k years old!!!
Boom!
In a first, scientists sequence the oldest RNA from a 39,000-year-old woolly mammoth wapo.st/4qXwTxU
How a frozen mammoth named Yuka is redefining the study of ancient RNA
Scientists sequence the oldest RNA from a 39,000-year-old woolly mammoth.
wapo.st
November 14, 2025 at 6:18 PM
Boom!
✅microRNAs for the win 💪🏻
November 14, 2025 at 6:17 PM
✅microRNAs for the win 💪🏻
Reposted by The Fromm Lab
Scientists have extracted the oldest RNA molecules out of a wooly mammoth, gaining a snapshot into the processes at work in the extinct mammal's body just before it died. n.pr/4patABW
Scientists pull ancient RNA from a wooly mammoth's body
Scientists have extracted the oldest RNA molecules out of a wooly mammoth, gaining a snapshot into the processes at work in the extinct mammal's body just before it died.
n.pr
November 14, 2025 at 5:41 PM
Scientists have extracted the oldest RNA molecules out of a wooly mammoth, gaining a snapshot into the processes at work in the extinct mammal's body just before it died. n.pr/4patABW
🦣🔥Annnnnnnd it is out!!! 🔥🦣
Mammoth RNA published in CELL @cellpress.bsky.social
Great collaboration with the labs of @marcfriedlander.bsky.social and @lovedalen.bsky.social lead by @marmole6.bsky.social
Mammoth RNA published in CELL @cellpress.bsky.social
Great collaboration with the labs of @marcfriedlander.bsky.social and @lovedalen.bsky.social lead by @marmole6.bsky.social
🦣🧬🦣🤯💥We are pleased to share our new paper about ancient RNA expression profiles from the Woolly Mammoth, now published in Cell @cellpress.bsky.social
www.cell.com/cell/fulltex...
If you want to know more, read the 🧵 below:
www.cell.com/cell/fulltex...
If you want to know more, read the 🧵 below:
November 14, 2025 at 5:57 PM
🦣🔥Annnnnnnd it is out!!! 🔥🦣
Mammoth RNA published in CELL @cellpress.bsky.social
Great collaboration with the labs of @marcfriedlander.bsky.social and @lovedalen.bsky.social lead by @marmole6.bsky.social
Mammoth RNA published in CELL @cellpress.bsky.social
Great collaboration with the labs of @marcfriedlander.bsky.social and @lovedalen.bsky.social lead by @marmole6.bsky.social
…this will soon be formatted nicely and we will follow swiftly with a threadorial!!!
Coming soon — the most comprehensive (and challenging) analysis yet of how all elements of the regulatory genome correlate with animal complexity and morphological disparity. With #KevinPeterson, @frommlab.bsky.social, and other luminaries. A link to the paper. www.researchgate.net/publication/...
(PDF) Exploring the Genotype-to-Phenotype Map Using Quantifiable Patterns in Metazoan Genomic and Morphological Data
PDF | On Nov 11, 2025, Kevin J. Peterson and others published Exploring the Genotype-to-Phenotype Map Using Quantifiable Patterns in Metazoan Genomic and Morphological Data | Find, read and cite all t...
www.researchgate.net
November 12, 2025 at 2:13 PM
…this will soon be formatted nicely and we will follow swiftly with a threadorial!!!
Reposted by The Fromm Lab
The Lepidoptera are leading the race in reference genome comparative genomics -- beating the Diptera and Drosophila as a model. ecoevorxiv.org/repository/v...
November 4, 2025 at 5:24 AM
The Lepidoptera are leading the race in reference genome comparative genomics -- beating the Diptera and Drosophila as a model. ecoevorxiv.org/repository/v...
Reposted by The Fromm Lab
Gelechioidea, that superdiverse superfamily of Lepidoptera that has been a super mess taxonomically, finally gets some structure at the family level with phylogenomics! Read all about it in our article led by PhD student @etkayapar.bsky.social !
resjournals.onlinelibrary.wiley.com/doi/10.1111/...
resjournals.onlinelibrary.wiley.com/doi/10.1111/...
Integrating Sanger and next‐generation sequencing data sheds light on phylogenetic relationships among gelechioid moths (Lepidoptera: Gelechioidea)
The maximum-likelihood analysis of a phylogenomic dataset of 1767 protein-coding genes from 57 ingroup taxa yields a robust family-level topology for Gelechioidea, revealing novel among-family relat...
resjournals.onlinelibrary.wiley.com
October 30, 2025 at 12:44 PM
Gelechioidea, that superdiverse superfamily of Lepidoptera that has been a super mess taxonomically, finally gets some structure at the family level with phylogenomics! Read all about it in our article led by PhD student @etkayapar.bsky.social !
resjournals.onlinelibrary.wiley.com/doi/10.1111/...
resjournals.onlinelibrary.wiley.com/doi/10.1111/...
In German a contribution to the topic of papermills and what we might be able to do about it!
"Wenn Betrug schneller wächst als die Wahrheit" — Ein Gastbeitrag von Bastian Fromm (@frommlab.bsky.social, Universität Tromsø) zum Thema organisierte #Forschungsfälschung & #PaperMills und was dies für eine funktionierende #Wissenschaft bedeutet: www.laborjournal.de/editorials/3...
October 31, 2025 at 3:40 PM
In German a contribution to the topic of papermills and what we might be able to do about it!
Reposted by The Fromm Lab
"Wenn Betrug schneller wächst als die Wahrheit" — Ein Gastbeitrag von Bastian Fromm (@frommlab.bsky.social, Universität Tromsø) zum Thema organisierte #Forschungsfälschung & #PaperMills und was dies für eine funktionierende #Wissenschaft bedeutet: www.laborjournal.de/editorials/3...
October 31, 2025 at 9:05 AM
"Wenn Betrug schneller wächst als die Wahrheit" — Ein Gastbeitrag von Bastian Fromm (@frommlab.bsky.social, Universität Tromsø) zum Thema organisierte #Forschungsfälschung & #PaperMills und was dies für eine funktionierende #Wissenschaft bedeutet: www.laborjournal.de/editorials/3...
Reposted by The Fromm Lab
Well reported story on the PBS News Hour about science cuts and the ongoing and potential brain drain.
www.youtube.com/watch?v=yLvO...
Thanks to Terrance Tao and other scientists at various career stages for having the courage to speak out.
Watch and share!
1/7
www.youtube.com/watch?v=yLvO...
Thanks to Terrance Tao and other scientists at various career stages for having the courage to speak out.
Watch and share!
1/7
Top researchers consider leaving U.S. amid funding cuts: 'The science world is ending'
YouTube video by PBS NewsHour
www.youtube.com
October 30, 2025 at 11:36 AM
Well reported story on the PBS News Hour about science cuts and the ongoing and potential brain drain.
www.youtube.com/watch?v=yLvO...
Thanks to Terrance Tao and other scientists at various career stages for having the courage to speak out.
Watch and share!
1/7
www.youtube.com/watch?v=yLvO...
Thanks to Terrance Tao and other scientists at various career stages for having the courage to speak out.
Watch and share!
1/7
Reposted by The Fromm Lab
Why has this microRNA review paper been cited more than 2,000 times?
Our Sleuth in Residence @drg.bsky.social digs in
Our Sleuth in Residence @drg.bsky.social digs in
Why has this microRNA review paper been cited more than 2,000 times?
Earlier this year, Marc Halushka, a pathologist at Cleveland Clinic in Ohio, came across a review titled simply “MicroRNA,” an unusually short title in a big field. Looking deeper into the re…
retractionwatch.com
September 17, 2025 at 2:16 PM
Why has this microRNA review paper been cited more than 2,000 times?
Our Sleuth in Residence @drg.bsky.social digs in
Our Sleuth in Residence @drg.bsky.social digs in
Reposted by The Fromm Lab
#2. This highlights the continuing shame of major journals doing a poor job of finding quality reviewers and not being responsible for the dubious work in their journals. They seem to want the flash, but are unwilling to clean up the messes they create.
October 22, 2025 at 4:28 PM
#2. This highlights the continuing shame of major journals doing a poor job of finding quality reviewers and not being responsible for the dubious work in their journals. They seem to want the flash, but are unwilling to clean up the messes they create.