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Frank Zaucke @fzaucke.bsky.social · 19d

Amazing! Thanks for this great overview👏😊

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Frank Zaucke @fzaucke.bsky.social · Sep 11

Fantastic line-up of speakers!
If you are interested in matrix research, please come to Heidelberg🤗

DGMB @matrixbiologie.bsky.social · Sep 11

While we update our website regarding #DGMB2026, you can find a list of confirmed speakers here! 👇 We are so happy to have them and already look forward to lots of exciting science!
#ECRs, we'll have a pre-meeting together with the #EU-CHANGE network - more info coming soon! #ECM #MatrixBiology

The annual meeting of the German Society for Matrix Biology will be held in Heidelberg, 15th - 17th of April, 2026. The flyer shows the "Alte Brücke" in Heidelberg Old Town.
Confirmed speakers are: Stefan Hell, Molly Stevens (online), Mats Paulsson, Viola Vogel, Leonhard Möckl, Florence Ruggiero, Tristan März, Sabine Eming, David Wilkinson, Christine Chuang, Oscar Staufer, Frauke Gräter, Markus Krüger and Veronique Orian-Rousseau.

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Frank Zaucke @fzaucke.bsky.social · Aug 12

Congratulations Blandine🤲👐🫶👏all the best 🍀🍀for the entire family!

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Frank Zaucke @fzaucke.bsky.social · Aug 11

The final version of our recent review on challenges in the development of DMOADs is available here👍

#osteaorthritis

rdcu.be/eAflJ

Emerging concepts and challenges in the development of disease-modifying osteoarthritis drugs – a more refined perspective

rdcu.be

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Reposted by Frank Zaucke

Journal of Cell Science @jcellsci.bsky.social · Jul 16

Rijuta Lamba, Alexandra Naba @nabalabuic.bsky.social, @valerioizzi.bsky.social and team present MatriCom, a single-cell RNA-sequencing data mining tool to infer cell–ECM interactions.
Highlight: journals.biologists.com/jcs/article/...
Article: journals.biologists.com/jcs/article/...
#OpenAccess

Figure showing the building MatriComDB, an omnibus database of matrisome protein interactions.

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Frank Zaucke @fzaucke.bsky.social · Jul 16

Hi Sarah, I am here😉
Huge congrats on this achievement.👍💪👏 Looking forward to making a small contribution😊

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Frank Zaucke @fzaucke.bsky.social · Jun 16

Great meeting! Hope to see many of you there👇

DGMB @matrixbiologie.bsky.social · Jun 3

📣SAVE THE DATE!

#DGMB2026 will be held 15th-17th April 2026 in beautiful Heidelberg! More details to follow soon!

We will also have a satellite meeting for #EarlyCareerResearchers before the main meeting, giving you a chance to meet other #ECRs and make new conference-friends! #matrixbiology

SAVE THE DATE: 15.-17. April 2026. Annual meeting of the German Society for Matrix Biology. Scientific committee: PD Dr. Solvig Diederichs, Dr. Helen Dietmar, Prof. Dr. Anja Niehoff, Dr. Paolo Alberton, Dr. Muzamil Khan.

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Reposted by Frank Zaucke

Goethe-Universität Frankfurt @goetheuni.bsky.social · Jun 13

🚨 1 Milliarde Euro würde fehlen – was bedeutet das für Forschung & Lehre an hessischen #Hochschulen? Unser Präsident Prof. Dr. Enrico Schleiff findet klare Worte zum aktuellen Entwurf des Hochschulpakts. Jetzt ansehen und teilen! #Hochschulpakt #GoetheUni #Hessen

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Frank Zaucke @fzaucke.bsky.social · Jun 6

Please have a look at this recent review on #osteoarthritis.
Thanks to Mario Rothbauer and the entire team for letting me contribute!

rdcu.be/epH7q

Beyond symptomatic alignment: evaluating the integration of causal mechanisms in matching animal models with human pathotypes in osteoarthritis research | Arthritis Research & Therapy

rdcu.be

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Frank Zaucke @fzaucke.bsky.social · May 14

Excited to share our latest work on a novel mutation in a gene that causes non-classical OI👇

url:https://academic.oup.com/jbmrplus/article/doi/10.1093/jbmrpl/ziaf083/8128480

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Frank Zaucke @fzaucke.bsky.social · Apr 1

Please have a look at and enjoy reading the latest publication I have contributed to😉

Nature Reviews Rheumatology @natrevrheum.nature.com · Mar 28

New content online:

Restoring articular cartilage: insights from structure, composition and development

Nature Reviews Rheumatology, Published online: 28 March 2025; doi:10.1038/s41584-025-01236-7Insights from the composition, structure and development of articular cartilage are key for long-term therapeutic strategies to restore articular cartilage. The authors emphasize that future therapies should replicate the depth-dependent alignment of collagen and its interactions with the extracellular matrix to produce implants that mimic the biomechanical properties of cartilage.

bit.ly

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Frank Zaucke @fzaucke.bsky.social · Mar 13

Congrats, Catherine!

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Frank Zaucke @fzaucke.bsky.social · Mar 12

Now, the same group (including myself😉) presents data on how other cartilage biomarkers are changed as a result of immobilization.

Immobilization by 21-days of bed rest causes changes in biomarkers of ... www.sciencedirect.com/science/arti...

Immobilization by 21-days of bed rest causes changes in biomarkers of cartilage homeostasis in healthy individuals

To investigate the effects of 21 days bed rest immobilization (with and without exercise and nutrition intervention) on serum concentrations of cartil…

www.sciencedirect.com

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Frank Zaucke @fzaucke.bsky.social · Mar 12

In 2024, the effect of immobilization (by a 21 day bed rest) on the degradation of collagen II was published in the journal Osteoarthritis and Cartilage by Liphardt et al.

Immobilization by 21 days of bed rest results in type II collagen degr... www.sciencedirect.com/science/arti...

Immobilization by 21 days of bed rest results in type II collagen degradation in healthy individuals

To investigate the effects of 21 days of bed rest immobilization (with and without exercise and nutrition interventions) on type II collagen biomarker…

www.sciencedirect.com

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Frank Zaucke @fzaucke.bsky.social · Feb 28

Honoured to be invited to such a fantastic meeting!

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Frank Zaucke @fzaucke.bsky.social · Jan 29

Congrats, Tom! Matrix rules💪☺️

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Frank Zaucke @fzaucke.bsky.social · Jan 22

I'll be there👇😉

Orthopaedic Research Society @orssociety.bsky.social · Jan 21

You’re invited to one of the most anticipated events of #ORS2025, the JOR Editorial Recognition Dinner and Networking Reception. Join us for an evening of celebration, networking, and fun. Registration required. Learn more and register now: bit.ly/4g9rwGd

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Frank Zaucke @fzaucke.bsky.social · Jan 18

Are you attending the annual meeting of the Orthopaedic Research Society #ORS2025 meeting in Phoenix?
If so👇

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Frank Zaucke @fzaucke.bsky.social · Jan 16

With the following link
authors.elsevier.com/c/1kPnD3Im5h...
you have free access (for 50 days) to a recent study that our lab contributed to. We thank the lead authors for involving in this exciting project.

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Frank Zaucke @fzaucke.bsky.social · Jan 14

Amazing study!👇

Geert Carmeliet @geertlab.bsky.social · Jan 13

Big congratulations to Shauni Loopmans for her excellent PhD research, now online in @natmetabolism.bsky.social. This study reveals that the pentose phosphate pathway in #chondrocytes is crucial for ER redox homeostasis and cell survival rdcu.be/d5Q65 (1/3)

The pentose phosphate pathway controls oxidative protein folding and prevents ferroptosis in chondrocytes

Nature Metabolism - Loopmans et al. show that the pentose phosphate pathway in chondrocytes provides reducing power to ensure proteostasis necessary for bone lengthening.

rdcu.be

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Frank Zaucke @fzaucke.bsky.social · Jan 3

Congratulations! Very nice images👍

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Frank Zaucke @fzaucke.bsky.social · Dec 17

In case you are interested in the role of the #ECM in inherited skeletal disorders other than #osteogenesis imperfecta like e.g. #Marfan or #Ehlers-Danlos, #achondroplasia, #ciliopathies: watch out for this book that will be published soon (January 2025)!

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Frank Zaucke @fzaucke.bsky.social · Dec 14

🚨publication alert🚨 Open Access!
Please have a look at our latest review:
doi.org/10.1515/jpem...

Osteogenesis imperfecta: shifting paradigms in pathophysiology and care in children

The formation of functional bone requires a delicate interplay between osteogenesis and osteolysis. Disturbances in this subtle balance result in an increased risk for fractures. Besides its mechanica...

doi.org

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Frank Zaucke @fzaucke.bsky.social · Dec 4

Spectacular view of #Cologne yesterday evening

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Frank Zaucke @fzaucke.bsky.social · Nov 27

A very dark bluesky yesterday evening in Frankfurt

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