Joao Pereira
@jdpereira.bsky.social
5.1K followers 2K following 1.7K posts
Neuroscientist. Assistant Professor of Neurology at UAB Trying for a better, more humane approach to science. Interested in neurodegenerative diseases, AI toolsets, and science in general! STOP ALS.
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jdpereira.bsky.social
“But when I see something
I’ll reach and grab some wings
And fly away
During the day

Why can’t people do the same as birds?
I’ll say it with other words:
Why am I heavy and not light?
And why can’t I see it too?
A perfect bird’s eye view
When the sun is shining bright.”

7yo.

(Now 8yo)
jdpereira.bsky.social
Playing songs on speakers.

My running playlist comes up: techno syndrome (don’t look at me that way the song rocks).

9yo just screams:
a poster for mortal kombat shows a dragon in a circle
ALT: a poster for mortal kombat shows a dragon in a circle
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jdpereira.bsky.social
Not ready yet, I’m afraid! Early days :)
jdpereira.bsky.social
Ok, ok, so hear me out, bulk RNAseq on these ALS organoids is giving out some cool stuff, which we’re now validating with sc-RNAseq.

Cool, cool stuff.
a man with gray hair and a yellow jacket is smiling .
ALT: a man with gray hair and a yellow jacket is smiling .
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jdpereira.bsky.social
I arrived after work today and sat on the couch with one of the twins, who was reading.

Spouse asks where he is:

“Oh, he’s with me, we’re just here, cuddling.”

And I kid you not, he looks at me lovingly, hugs me and cuddles next to me.

These boys will be breaking hearts.

And I get it. I get it.
a man in a suit and tie is holding his eyes closed and saying `` i get it '' .
ALT: a man in a suit and tie is holding his eyes closed and saying `` i get it '' .
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jdpereira.bsky.social
For your consideration:

- packet of diapers (19 count)
- eggs (30 count)
- peanut butter
- jelly
- 3x gallon whole milk.

$43
a video game that says it 's dangerous to go alone
ALT: a video game that says it 's dangerous to go alone
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jdpereira.bsky.social
Hey, nowadays that is the Google experience…
jdpereira.bsky.social
These babies now walk to the stove, holding bowls with their best “can I have some more, sir?” faces.

It’s uncanny: the first two years are an insane amount of learning, and I swear 90% of it is “what are the buttons and how can I push them?”
a cartoon cat is wearing a black beanie and standing in front of a sign that says push the button
ALT: a cartoon cat is wearing a black beanie and standing in front of a sign that says push the button
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jdpereira.bsky.social
Why I despise refunds:

- they happen 2 months after the fact.
- you’re paying interest while you wait
- if you get a wire transfer you actually may pay fees.

It sucks.

It is predating on our young, and it sucks.

Did I mention it sucks?

Sigh.
a donkey from shrek is standing in the dirt and says nope on the bottom
ALT: a donkey from shrek is standing in the dirt and says nope on the bottom
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jdpereira.bsky.social
Honestly, the Gurdon is so special, and a great part of that is/was John.

To this day, it is the one place I would go back to.
jdpereira.bsky.social
www.cam.ac.uk/research/new...

I am shocked.

I know, 92, I shouldn’t be.

But Sir John Gurdon was so full of life!

I recall a conversation over breakfast at the Gurdon Institute, where Sir John, about 80 at the time, was complaining about not quite being able to do figure 8s ice-skating.

Goals.
Nobel Laureate Professor Sir John Gurdon dies aged 92
It is with great sadness that the University shares the news of the death of Professor Sir John Gurdon, founder of the Gurdon Institute.
www.cam.ac.uk
jdpereira.bsky.social
It was not directed at any of the grown ups :P
jdpereira.bsky.social
Hey, iPSC folk - anyone have some cool Rett syndrome iPSC lines with isogenic controls they are willing to part with?

Asking for…. Well, me.

We have found something cool in another model we would love to test :)
a groundhog is standing on a rock with its mouth open and saying hey ! hey ! hey !
ALT: a groundhog is standing on a rock with its mouth open and saying hey ! hey ! hey !
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jdpereira.bsky.social
“What did you do today?”

“Well I finished a readable draft of my specific aims for an R01, and sent it to a bunch of people so they can absolutely trash it before I have to show it to another group of people so they can trash it.”

“Academia is fun, right?”

“Right.”
a man in a suit and tie is talking to a woman and the words sureeeee are visible
ALT: a man in a suit and tie is talking to a woman and the words sureeeee are visible
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jdpereira.bsky.social
Thanks. Definitely mixed emotions here.
jdpereira.bsky.social
I dunno, I’ll let you know how it goes.
jdpereira.bsky.social
I once had an uncle that was a famous, talented painter. I was very, very proud of him.

He was not a good person, at least not to us.

And I haven’t spoken to him in 24 years.

And now I don’t have an uncle that was a famous painter anymore and I don’t know how I feel.
a woman says honestly i don 't know in a netflix ad
ALT: a woman says honestly i don 't know in a netflix ad
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jdpereira.bsky.social
Far beyond my meager skills.
jdpereira.bsky.social
I did this with mine last year (her third grade!) it was actually a lot of fun!
jdpereira.bsky.social
My dude, is that the king knighting a queen?
jdpereira.bsky.social
I was helping spouse with some website issues.

Babies want to go their cribs.

Now, they only do that when they want to jump and down and dance.

Everyone, turns out my 19 month twins unlocked my phone, turned on YouTube music, and managed to put on Kuduro.

Which I promise, we don’t play. Ever.
two south park characters standing next to each other with the words yeah but how
ALT: two south park characters standing next to each other with the words yeah but how
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jdpereira.bsky.social
Girls watch a random show on Netflix.

Theme song plays.

Wait. I know that song.

I’ve heard it.

But I don’t know the cartoon, how do I know the song?

It was from something… something cool, but I don’t reme.. oh.

OH.

So that’s the cartoon that goes with it.

Huh. Wouldn’t have thunk it.
a red cat mascot is playing drums on a stage .
Alt: a red cat mascot is playing drums on a stage . Insanely well.
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jdpereira.bsky.social
Oh yes, I do that all the time ;)