Jordy Cohen
@jordybc.bsky.social
Nephrologist, epidemiologist, methods nerd, climber, hypertension, MedEd, @ PennKidney
https://dbei.med.upenn.edu/staff/jordana-cohen-md-msce/
https://dbei.med.upenn.edu/staff/jordana-cohen-md-msce/
Reposted by Jordy Cohen
Agree with your comments
It mostly seems an extension/explanation of the ridiculous 2023 ESH guidelines (not to be confused with the superb 2024 ESC guidelines www.escardio.org/Guidelines/C...)
A whole section to renal denervation 🤔
And such strong language against BP < 120
It mostly seems an extension/explanation of the ridiculous 2023 ESH guidelines (not to be confused with the superb 2024 ESC guidelines www.escardio.org/Guidelines/C...)
A whole section to renal denervation 🤔
And such strong language against BP < 120
ESC Guidelines for the management of elevated blood pressure and hypertension
ESC Clinical Practice Guidelines aim to present all the relevant evidence to help physicians weigh the benefits and risks of a particular diagnostic or therapeutic procedure for the management of ele...
www.escardio.org
November 23, 2025 at 3:58 PM
Agree with your comments
It mostly seems an extension/explanation of the ridiculous 2023 ESH guidelines (not to be confused with the superb 2024 ESC guidelines www.escardio.org/Guidelines/C...)
A whole section to renal denervation 🤔
And such strong language against BP < 120
It mostly seems an extension/explanation of the ridiculous 2023 ESH guidelines (not to be confused with the superb 2024 ESC guidelines www.escardio.org/Guidelines/C...)
A whole section to renal denervation 🤔
And such strong language against BP < 120
Reposted by Jordy Cohen
@jordybc.bsky.social this you?
Looks like an issue of JACC that needs to be read!
Looks like an issue of JACC that needs to be read!
November 21, 2025 at 5:42 AM
@jordybc.bsky.social this you?
Looks like an issue of JACC that needs to be read!
Looks like an issue of JACC that needs to be read!
Reposted by Jordy Cohen
There you go:
www.ahajournals.org/doi/10.1161/...
@ahascience.bsky.social statement from HT heavyweights
www.ahajournals.org/doi/10.1161/...
@ahascience.bsky.social statement from HT heavyweights
The Management of Elevated Blood Pressure in the Acute Care Setting: A Scientific Statement From the American Heart Association | Hypertension
Over the past 3 decades, a substantial body of high-quality evidence has guided the
diagnosis and management of elevated blood pressure (BP) in the outpatient setting.
In contrast, there is a lack of ...
www.ahajournals.org
September 29, 2025 at 12:22 AM
There you go:
www.ahajournals.org/doi/10.1161/...
@ahascience.bsky.social statement from HT heavyweights
www.ahajournals.org/doi/10.1161/...
@ahascience.bsky.social statement from HT heavyweights
Reposted by Jordy Cohen
High blood pressure often shows no symptoms, but raises risk of stroke, heart disease, kidney damage, and dementia.
New American Heart Association guidelines: treat it early with diet & exercise.
“If you catch it early, you can gain many more years of healthy life,” says Penn’s Dr. Jordana Cohen.
New American Heart Association guidelines: treat it early with diet & exercise.
“If you catch it early, you can gain many more years of healthy life,” says Penn’s Dr. Jordana Cohen.
The silent killer increases your risk of stroke and dementia. Here's how to control it
New recommendations for early treatment of hypertension to prevent strokes, heart attacks and dementia come as an experimental medication is shown to lower blood pressure in hard-to-treat patients.
www.npr.org
September 18, 2025 at 4:20 PM
High blood pressure often shows no symptoms, but raises risk of stroke, heart disease, kidney damage, and dementia.
New American Heart Association guidelines: treat it early with diet & exercise.
“If you catch it early, you can gain many more years of healthy life,” says Penn’s Dr. Jordana Cohen.
New American Heart Association guidelines: treat it early with diet & exercise.
“If you catch it early, you can gain many more years of healthy life,” says Penn’s Dr. Jordana Cohen.
Reposted by Jordy Cohen
And that’s a wrap!
In summary: screen carefully, stratify by risk, account for kidney health, and individualize therapy.
For nephrology, the wins are undeniable: albuminuria testing is mainstream, CKD visibility is heightened, and aldosterone is on the radar.
#NephJC
In summary: screen carefully, stratify by risk, account for kidney health, and individualize therapy.
For nephrology, the wins are undeniable: albuminuria testing is mainstream, CKD visibility is heightened, and aldosterone is on the radar.
#NephJC
September 17, 2025 at 1:54 AM
And that’s a wrap!
In summary: screen carefully, stratify by risk, account for kidney health, and individualize therapy.
For nephrology, the wins are undeniable: albuminuria testing is mainstream, CKD visibility is heightened, and aldosterone is on the radar.
#NephJC
In summary: screen carefully, stratify by risk, account for kidney health, and individualize therapy.
For nephrology, the wins are undeniable: albuminuria testing is mainstream, CKD visibility is heightened, and aldosterone is on the radar.
#NephJC
Reposted by Jordy Cohen
T4l
1️⃣2️⃣No aggressive IV treatment for severe asymptomatic HTN - avoid acute inpatient lowering if no target-organ damage (COR III: Harm, LOE C-LD).
📝Treat the patient (situation) not the number for acute HTN during hospitalization. I have trouble convincing nocturnists of this. #NephJC
1️⃣2️⃣No aggressive IV treatment for severe asymptomatic HTN - avoid acute inpatient lowering if no target-organ damage (COR III: Harm, LOE C-LD).
📝Treat the patient (situation) not the number for acute HTN during hospitalization. I have trouble convincing nocturnists of this. #NephJC
September 17, 2025 at 1:51 AM
T4l
1️⃣2️⃣No aggressive IV treatment for severe asymptomatic HTN - avoid acute inpatient lowering if no target-organ damage (COR III: Harm, LOE C-LD).
📝Treat the patient (situation) not the number for acute HTN during hospitalization. I have trouble convincing nocturnists of this. #NephJC
1️⃣2️⃣No aggressive IV treatment for severe asymptomatic HTN - avoid acute inpatient lowering if no target-organ damage (COR III: Harm, LOE C-LD).
📝Treat the patient (situation) not the number for acute HTN during hospitalization. I have trouble convincing nocturnists of this. #NephJC
Reposted by Jordy Cohen
T4j
🔟CKD with albuminuria - ACEi/ARB strongly recommended to delay CKD progression and reduce CVD (COR I, LOE A).
📝Still only 35-50% of eligible patients get them. How do we move the needle on this? #NephJC
🔟CKD with albuminuria - ACEi/ARB strongly recommended to delay CKD progression and reduce CVD (COR I, LOE A).
📝Still only 35-50% of eligible patients get them. How do we move the needle on this? #NephJC
September 17, 2025 at 1:49 AM
T4j
🔟CKD with albuminuria - ACEi/ARB strongly recommended to delay CKD progression and reduce CVD (COR I, LOE A).
📝Still only 35-50% of eligible patients get them. How do we move the needle on this? #NephJC
🔟CKD with albuminuria - ACEi/ARB strongly recommended to delay CKD progression and reduce CVD (COR I, LOE A).
📝Still only 35-50% of eligible patients get them. How do we move the needle on this? #NephJC
Reposted by Jordy Cohen
T4i
9️⃣Cognitive protection🧠 - treat to SBP <130 to prevent mild cognitive impairment/dementia (COR I, LOE B-R).
📝Do you think BP control has a significant role in dementia? #NephJC
9️⃣Cognitive protection🧠 - treat to SBP <130 to prevent mild cognitive impairment/dementia (COR I, LOE B-R).
📝Do you think BP control has a significant role in dementia? #NephJC
September 17, 2025 at 1:48 AM
T4i
9️⃣Cognitive protection🧠 - treat to SBP <130 to prevent mild cognitive impairment/dementia (COR I, LOE B-R).
📝Do you think BP control has a significant role in dementia? #NephJC
9️⃣Cognitive protection🧠 - treat to SBP <130 to prevent mild cognitive impairment/dementia (COR I, LOE B-R).
📝Do you think BP control has a significant role in dementia? #NephJC
Reposted by Jordy Cohen
September 17, 2025 at 1:42 AM
Reposted by Jordy Cohen
I would dare to say many people: if too young, if single pill combo is not enough to control BP. PA is more common than we are used to think. Usually, for us nephrologists is even harder to screen when pts are already on 4-5meds #nephjc
www.nephjc.com/news/primary...
www.nephjc.com/news/primary...
Undercover Aldosterone — NephJC
This week, we will discuss the origins of primary hyperaldosteronism in normotensive patients. Could this undetected anomaly be the cause of idiopathic hypertension and CKD?
www.nephjc.com
September 17, 2025 at 1:30 AM
I would dare to say many people: if too young, if single pill combo is not enough to control BP. PA is more common than we are used to think. Usually, for us nephrologists is even harder to screen when pts are already on 4-5meds #nephjc
www.nephjc.com/news/primary...
www.nephjc.com/news/primary...
Reposted by Jordy Cohen
T0b
Is HTN still a problem worth our attention? Haven’t we conquered this ‘Silent Killer’ yet? Answers: YES it’s a problem, NO we’ve not conquered it.
#NephJC
Is HTN still a problem worth our attention? Haven’t we conquered this ‘Silent Killer’ yet? Answers: YES it’s a problem, NO we’ve not conquered it.
#NephJC
September 17, 2025 at 1:10 AM
T0b
Is HTN still a problem worth our attention? Haven’t we conquered this ‘Silent Killer’ yet? Answers: YES it’s a problem, NO we’ve not conquered it.
#NephJC
Is HTN still a problem worth our attention? Haven’t we conquered this ‘Silent Killer’ yet? Answers: YES it’s a problem, NO we’ve not conquered it.
#NephJC
Reposted by Jordy Cohen
T0c
Check out these sobering stats:
➡️More than 1.3 billion with HTN globally, 1.2 billion without control
➡️46.7 % HTN prevalence in the US from 2017 to 2020
➡️Leading cause of death and disability worldwide
#NephJC
Check out these sobering stats:
➡️More than 1.3 billion with HTN globally, 1.2 billion without control
➡️46.7 % HTN prevalence in the US from 2017 to 2020
➡️Leading cause of death and disability worldwide
#NephJC
September 17, 2025 at 1:11 AM
T0c
Check out these sobering stats:
➡️More than 1.3 billion with HTN globally, 1.2 billion without control
➡️46.7 % HTN prevalence in the US from 2017 to 2020
➡️Leading cause of death and disability worldwide
#NephJC
Check out these sobering stats:
➡️More than 1.3 billion with HTN globally, 1.2 billion without control
➡️46.7 % HTN prevalence in the US from 2017 to 2020
➡️Leading cause of death and disability worldwide
#NephJC
Jordy Cohen from University of Pennsylvania here for what’s certain to be an exciting #nephjc!
I’m perhaps biased as a member of the writing committee of the 2025 AHA/ACC BP guideline…
No other COIs
I’m perhaps biased as a member of the writing committee of the 2025 AHA/ACC BP guideline…
No other COIs
a stuffed animal wearing a hockey helmet and a beard
Alt: Gritty giving two peace signs
media.tenor.com
September 17, 2025 at 1:08 AM
Jordy Cohen from University of Pennsylvania here for what’s certain to be an exciting #nephjc!
I’m perhaps biased as a member of the writing committee of the 2025 AHA/ACC BP guideline…
No other COIs
I’m perhaps biased as a member of the writing committee of the 2025 AHA/ACC BP guideline…
No other COIs
Reposted by Jordy Cohen
⏰2 hours until #NephJC chat
🔍 Tonight we are talking about the 2025 ACC/AHA Blood Pressure guidelines! Eight years have passed since the last update. What’s different? What’s the same? Tonight we tackle it all!
🔍 Tonight we are talking about the 2025 ACC/AHA Blood Pressure guidelines! Eight years have passed since the last update. What’s different? What’s the same? Tonight we tackle it all!
2025 AHA/ACC/AANP/AAPA/ABC/ACCP/ACPM/AGS/AMA/ASPC/NMA/PCNA/SGIM Guideline for the Prevention, Detection, Evaluation and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines | Hypertension
AIM: The “2025 AHA/ACC/AANP/AAPA/ABC/ACCP/ACPM/AGS/AMA/ASPC/NMA/PCNA/SGIM Guideline for
the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults”
retires and replaces the “2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline
for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in
Adults.” METHODS: A comprehensive literature search was conducted from December 2023 to June 2024 to
identify clinical studies, reviews, and other evidence performed on human subjects
that were published since February 2015 in English from MEDLINE (through PubMed),
EMBASE, the Cochrane Library, the Agency for Healthcare Research and Quality, and
other selected databases relevant to this guideline. STRUCTURE: The focus of this clinical practice guideline is to create a living, working document
updating current knowledge in the field of high blood pressure aimed at all practicing
primary care and specialty clinicians who manage patients with hypertension.
www.ahajournals.org
September 16, 2025 at 11:00 PM
⏰2 hours until #NephJC chat
🔍 Tonight we are talking about the 2025 ACC/AHA Blood Pressure guidelines! Eight years have passed since the last update. What’s different? What’s the same? Tonight we tackle it all!
🔍 Tonight we are talking about the 2025 ACC/AHA Blood Pressure guidelines! Eight years have passed since the last update. What’s different? What’s the same? Tonight we tackle it all!
Reposted by Jordy Cohen
Congratulations @robynwei.bsky.social RD/ PhD candidate for her poster #Hypertension25 highlighting underutilization of salt substitute use in the US @giaconajohn.bsky.social details in AHA News release newsroom.heart.org/news/u-s-sur... @ahascience.bsky.social
September 5, 2025 at 1:05 PM
Congratulations @robynwei.bsky.social RD/ PhD candidate for her poster #Hypertension25 highlighting underutilization of salt substitute use in the US @giaconajohn.bsky.social details in AHA News release newsroom.heart.org/news/u-s-sur... @ahascience.bsky.social
Reposted by Jordy Cohen
Dr Karol Watson starts with impactful message top 10 take away message #Hypertension25 high BP as predictor dementia and treatment reduces cognitive decline or dementia by 15% . Once you hit 120/80 , trajectory to high BP is steep. Don’t sit on high BP! @ahascience.bsky.social
September 5, 2025 at 2:41 PM
Dr Karol Watson starts with impactful message top 10 take away message #Hypertension25 high BP as predictor dementia and treatment reduces cognitive decline or dementia by 15% . Once you hit 120/80 , trajectory to high BP is steep. Don’t sit on high BP! @ahascience.bsky.social
Reposted by Jordy Cohen
Congratulations @ahascience.bsky.social @accintouch.bsky.social 2025 #BloodPressure #GLs Writing TaskForce incl @jordybc.bsky.social @drwanpen.bsky.social @daichishimbo.bsky.social @ycommodore.bsky.social
♥️ format #GLs 🔦 are presented with #patient case Hx & mgt 🥇
#Hypertension25
♥️ format #GLs 🔦 are presented with #patient case Hx & mgt 🥇
#Hypertension25
September 4, 2025 at 12:59 PM
Congratulations @ahascience.bsky.social @accintouch.bsky.social 2025 #BloodPressure #GLs Writing TaskForce incl @jordybc.bsky.social @drwanpen.bsky.social @daichishimbo.bsky.social @ycommodore.bsky.social
♥️ format #GLs 🔦 are presented with #patient case Hx & mgt 🥇
#Hypertension25
♥️ format #GLs 🔦 are presented with #patient case Hx & mgt 🥇
#Hypertension25
Reposted by Jordy Cohen
Beta blockers remain overused for #hypertension in the VA (though the tens line is going down, very slowly)
jamanetwork.com/journals/jam... in @jama.com from @jordybc.bsky.social et al
OTOH: I think ESRD should count as a somewhat compelling indication? Almost all HD pts here are on bisoprolol
jamanetwork.com/journals/jam... in @jama.com from @jordybc.bsky.social et al
OTOH: I think ESRD should count as a somewhat compelling indication? Almost all HD pts here are on bisoprolol
September 3, 2025 at 10:26 PM
Beta blockers remain overused for #hypertension in the VA (though the tens line is going down, very slowly)
jamanetwork.com/journals/jam... in @jama.com from @jordybc.bsky.social et al
OTOH: I think ESRD should count as a somewhat compelling indication? Almost all HD pts here are on bisoprolol
jamanetwork.com/journals/jam... in @jama.com from @jordybc.bsky.social et al
OTOH: I think ESRD should count as a somewhat compelling indication? Almost all HD pts here are on bisoprolol
Reposted by Jordy Cohen
Up next!
New AHA/ACC hypertension guidelines #NephJC
@ahascience.bsky.social @accintouch.bsky.social
New AHA/ACC hypertension guidelines #NephJC
@ahascience.bsky.social @accintouch.bsky.social
2025 AHA/ACC/AANP/AAPA/ABC/ACCP/ACPM/AGS/AMA/ASPC/NMA/PCNA/SGIM Guideline for the Prevention, Detection, Evaluation and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines | Circulation
AIM: The “2025 AHA/ACC/AANP/AAPA/ABC/ACCP/ACPM/AGS/AMA/ASPC/NMA/PCNA/SGIM Guideline for
the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults”
retires and replaces the “2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline
for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in
Adults.” METHODS: A comprehensive literature search was conducted from December 2023 to June 2024 to
identify clinical studies, reviews, and other evidence performed on human subjects
that were published since February 2015 in English from MEDLINE (through PubMed),
EMBASE, the Cochrane Library, the Agency for Healthcare Research and Quality, and
other selected databases relevant to this guideline. STRUCTURE: The focus of this clinical practice guideline is to create a living, working document
updating current knowledge in the field of high blood pressure aimed at all practicing
primary care and specialty clinicians who manage patients with hypertension.
www.ahajournals.org
September 3, 2025 at 1:54 AM
Up next!
New AHA/ACC hypertension guidelines #NephJC
@ahascience.bsky.social @accintouch.bsky.social
New AHA/ACC hypertension guidelines #NephJC
@ahascience.bsky.social @accintouch.bsky.social
Reposted by Jordy Cohen
The era of ASIs is slowly dawning
www.nejm.org/doi/full/10....
(Yeah spironolactone is just as good and cheaper)
Disclosure: we recruited patients for this one
www.nejm.org/doi/full/10....
(Yeah spironolactone is just as good and cheaper)
Disclosure: we recruited patients for this one
Efficacy and Safety of Baxdrostat in Uncontrolled and Resistant Hypertension | NEJM
Aldosterone dysregulation plays an important pathogenic role in hard-to-control hypertension.
In several studies, baxdrostat, an aldosterone synthase inhibitor, reduced the seated
systolic blood pr...
www.nejm.org
August 30, 2025 at 2:39 PM
The era of ASIs is slowly dawning
www.nejm.org/doi/full/10....
(Yeah spironolactone is just as good and cheaper)
Disclosure: we recruited patients for this one
www.nejm.org/doi/full/10....
(Yeah spironolactone is just as good and cheaper)
Disclosure: we recruited patients for this one
Reposted by Jordy Cohen
❓What’s new in BP care?
🎥 Watch the #TargetBP webinar on the 2025 @AHAScience / @ACCinTouch Hypertension Guidelines w/ @drwanpen.bsky.social , @jordybc.bsky.social , Keith Ferdinand, & Dan Jones 👉 targetbp.org
🎥 Watch the #TargetBP webinar on the 2025 @AHAScience / @ACCinTouch Hypertension Guidelines w/ @drwanpen.bsky.social , @jordybc.bsky.social , Keith Ferdinand, & Dan Jones 👉 targetbp.org
August 28, 2025 at 6:54 PM
❓What’s new in BP care?
🎥 Watch the #TargetBP webinar on the 2025 @AHAScience / @ACCinTouch Hypertension Guidelines w/ @drwanpen.bsky.social , @jordybc.bsky.social , Keith Ferdinand, & Dan Jones 👉 targetbp.org
🎥 Watch the #TargetBP webinar on the 2025 @AHAScience / @ACCinTouch Hypertension Guidelines w/ @drwanpen.bsky.social , @jordybc.bsky.social , Keith Ferdinand, & Dan Jones 👉 targetbp.org
Reposted by Jordy Cohen
Fascinating piece on the issues with AI slop in the mathematical research world (spoiler: it's a massive problem). Ping @carlbergstrom.com open.substack.com/pub/bristoli...
End of the peer show
I would not be convicted by a jury of my peers, still crazy after all these years
open.substack.com
August 23, 2025 at 11:36 PM
Fascinating piece on the issues with AI slop in the mathematical research world (spoiler: it's a massive problem). Ping @carlbergstrom.com open.substack.com/pub/bristoli...
Reposted by Jordy Cohen
Join us @jordybc.bsky.social , Keith Ferdinand, and Dan Jones unpacking 2025 AHA/ACC guidelines on Thursday Aug 28 bit.ly/Guideline25W... @UTSWInternalMed @utswheart
August 19, 2025 at 11:39 PM
Join us @jordybc.bsky.social , Keith Ferdinand, and Dan Jones unpacking 2025 AHA/ACC guidelines on Thursday Aug 28 bit.ly/Guideline25W... @UTSWInternalMed @utswheart
Reposted by Jordy Cohen
Thanks for sharing. So many great recommendations!
The devil is in the details, i.e. adoption/implementation. For starters, I suspect very few of the routine lab tests for new diagnosis of HTN are being ordered.
The devil is in the details, i.e. adoption/implementation. For starters, I suspect very few of the routine lab tests for new diagnosis of HTN are being ordered.
August 17, 2025 at 5:01 PM
Thanks for sharing. So many great recommendations!
The devil is in the details, i.e. adoption/implementation. For starters, I suspect very few of the routine lab tests for new diagnosis of HTN are being ordered.
The devil is in the details, i.e. adoption/implementation. For starters, I suspect very few of the routine lab tests for new diagnosis of HTN are being ordered.
Reposted by Jordy Cohen
The AHA/ACC have released the 2025 High Blood Pressure Guideline, emphasizing prevention and early treatment to reduce cardiovascular disease risk.
Read the Guideline in #Hypertension & #Circulation and check out our hub with commentaries and more:
www.ahajournals.org/guidelines/h...
#Cardiosky
Read the Guideline in #Hypertension & #Circulation and check out our hub with commentaries and more:
www.ahajournals.org/guidelines/h...
#Cardiosky
August 14, 2025 at 6:53 PM
The AHA/ACC have released the 2025 High Blood Pressure Guideline, emphasizing prevention and early treatment to reduce cardiovascular disease risk.
Read the Guideline in #Hypertension & #Circulation and check out our hub with commentaries and more:
www.ahajournals.org/guidelines/h...
#Cardiosky
Read the Guideline in #Hypertension & #Circulation and check out our hub with commentaries and more:
www.ahajournals.org/guidelines/h...
#Cardiosky