Jorge Lozano-Juste
jorgetwe.bsky.social
Jorge Lozano-Juste
@jorgetwe.bsky.social
180 followers 460 following 670 posts
Chemical Biology - Plant hormone signaling - Drug Discovery - Targeted Protein Degradation
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Had an awesome time at the Medicinal and Crop Protection Chemistry Meeting in Como, Italy 🇮🇹! Great to share our work at this unique event bridging pharma and agro drug discovery. Huge thanks to the organizers for an amazing lineup of speakers from academia and industry! 👏🌿💊
Reposted by Jorge Lozano-Juste
Algal pyrenoids—condensates that mediate ~1/3 of Earth’s CO2 fixation—change size and number as cells divide. Our data suggest a simple control mechanism: a kinase that continuously ejects material from the condensate! ☀️🌍🔬💧 #Biophysics #Photosynthesis
www.biorxiv.org/content/10.1...
Thanks again for the invitation! It was great to see you all and discuss our work with you. Kudos to the organizers for their perfect job!
Reposted by Jorge Lozano-Juste
📢 Don’t miss the upcoming seminar: ‘Drug discovery for thirsty plants’🌱, given by Dr Jorge Lozano Juste, Instituto de Biología Molecular y Celular de Plantas (@ibmcp.bsky.social ). Valencia.

🗓️26 September
🕛12:00h
📍CNB Lecture Hall
Reposted by Jorge Lozano-Juste
«Entre las demandas principales destacan la aprobación de un Estatuto del Personal de Investigación, la simplificación de trámites administrativos y el incremento de la inversión pública en I+D+i hasta alcanzar el 3% del PIB.»
www.larazon.es/ciencia/cien... vía @larazonlr.bsky.social
Científicos exigen este domingo el cumplimiento del Pacto por la Ciencia firmado en 2023
Varias plataformas convocan concentraciones en Madrid, Barcelona y Valencia para exigir que el Pacto por la Ciencia "no sea papel mojado"
www.larazon.es
Reposted by Jorge Lozano-Juste
'The rise of Chinese pharmaceutical innovation is reflected in the number of new drugs that were approved in China before being approved in any other country, which increased from 9 in 2018 to 45 — not including 3 traditional Chinese medicines — in 2024' www.nejm.org/doi/full/10....
Reposted by Jorge Lozano-Juste
S4.1. Molecular genetic mechanisms of plant development, evolution and adaptation

📢 Multisensory integration during plant terrestrialization - Miguel Blazquez @IBMCP 

#47congresosebbm
Reposted by Jorge Lozano-Juste
Delighted to share our work on cellular ubiquitination of drug-like compounds by HUWE1 - a surprising journey! Kudos to all contributors & first authors, Barbara Orth and Pavel Pohl. Sincere thanks to @ireserra.bsky.social#NatCommun for expertly guiding the winding publishing path.
rdcu.be/eDzPk
Selective ubiquitination of drug-like small molecules by the ubiquitin ligase HUWE1
Nature Communications - Ubiquitination is a versatile modification system in eukaryotic cells. Here, the authors unveil that the ubiquitin ligase HUWE1 can modify drug-like small-molecule...
rdcu.be
Reposted by Jorge Lozano-Juste
Reposted by Jorge Lozano-Juste
We are hiring the second cohort of EvoReSt PhD students. If you are interested in deep evolutionary questions, checkout:
www.uni-goettingen.de/de/687607.html
Apply here:
obp.uni-goettingen.de/de-de/OBF/In...
Reposted by Jorge Lozano-Juste
In the new book Labwork to Leadership, chemist Jen Heemstra offers actionable leadership advice to principal investigators.

Read the #ScienceBooks Review: https://scim.ag/4mljVr1
Why so expensive now? I got mine 3 years ago for 1/3 of that
Reposted by Jorge Lozano-Juste
Introducing the 1,000 Flower Collection 🧬🌹

I’m creating 1,000 genetically designed flowers each crafted with new colors, patterns, and shapes.

Here’s how I’m making it happen… and how you can join me on this journey 🧵(1/7)
Reposted by Jorge Lozano-Juste
(1/7)
Training biomolecular foundation models shouldn't be so hard. And open-source structure prediction is important. So today we're releasing two software packages: AtomWorks and RosettaFold3 (RF3)

[https://www.biorxiv.org/content/10.1101/2025.08.14.670328v2](www.biorxiv.org/content/10.1...)
Accelerating Biomolecular Modeling with AtomWorks and RF3
Deep learning methods trained on protein structure databases have revolutionized biomolecular structure prediction, but developing and training new models remains a considerable challenge. To facilita...
www.biorxiv.org
Reposted by Jorge Lozano-Juste
This review summarizes advancements in solubility and controllable aggregation tags for recombinant protein purification, highlighting design strategies, on-demand cleavage, and emerging production challenges.
#HM #protein #purification #tags #proteases
www.sciltp.com/journals/hm/...
Totally! I didn't think about that. Looks great btw
Reposted by Jorge Lozano-Juste
RosettaFold 3 is here! 🧬🚀

AtomWorks (the foundational data pipeline powering it) is perhaps the really most exciting part of this release!

Congratulations @simonmathis.bsky.social and team!!! ❤️

bioRxiv preprint: www.biorxiv.org/content/10.1...
Naive question: would it be better with black parts for the root system?
Reposted by Jorge Lozano-Juste
Congrats!! 👏🏼👏🏼
Reposted by Jorge Lozano-Juste
🍀🔬

Split-YFP-coupled interaction–dependent TurboID identifies new functions of basal cell polarity in Arabidopsis @pnas.org from Juan Dong's lab.

www.pnas.org/doi/10.1073/...
Reposted by Jorge Lozano-Juste
Hey all!
We have been awarded a Spanish national grant to keep researching. Best of all is we have a full PhD contract assigned. We are looking for candidates interested in molecular biology and evolution of (plant) transcription factors, please spread the word!!
Check our web for more information.