Juan Antonio Rodríguez
@jrotwitguez.bsky.social
MSCA Researcher @ Globe Institute (Copenhagen)
A cocktail of 3D genomes 🧬, GWAS, evolution and sprinkles of randomness.
Metagenomics and microbial things, lately. 🦠
Reposts with pH under 7, sometimes.
📍 Cedeira sempre, now in 🇩🇰
A cocktail of 3D genomes 🧬, GWAS, evolution and sprinkles of randomness.
Metagenomics and microbial things, lately. 🦠
Reposts with pH under 7, sometimes.
📍 Cedeira sempre, now in 🇩🇰
Pinned
New paper out! 📄
My first adventures in (ancient) metagenomics. 🦠
“Exploring DNA degradation in situ and in museum storage through genomics and metagenomics” www.nature.com/articles/s42...
Curious about the water color painting (see ALT text)? 🦌
Thread (Bluetorial?) with findings!
🧶👇 (1/n)
My first adventures in (ancient) metagenomics. 🦠
“Exploring DNA degradation in situ and in museum storage through genomics and metagenomics” www.nature.com/articles/s42...
Curious about the water color painting (see ALT text)? 🦌
Thread (Bluetorial?) with findings!
🧶👇 (1/n)
It was an amazing day-in-3D! Happy to have shar3D some insights on how to look at the genome from a different perspective
🧶🧬
(Thanks #MSCA @ec.europa.eu for funding through #POPARCH)
🧶🧬
(Thanks #MSCA @ec.europa.eu for funding through #POPARCH)
🧬3D genome workshop 🧬
🤩 Yesterday @jrotwitguez.bsky.social tought an awesome full day workshop on #3D #genomics to a full classroom @ucph.bsky.social
@dg.dk
🤩 Yesterday @jrotwitguez.bsky.social tought an awesome full day workshop on #3D #genomics to a full classroom @ucph.bsky.social
@dg.dk
November 22, 2025 at 3:02 PM
It was an amazing day-in-3D! Happy to have shar3D some insights on how to look at the genome from a different perspective
🧶🧬
(Thanks #MSCA @ec.europa.eu for funding through #POPARCH)
🧶🧬
(Thanks #MSCA @ec.europa.eu for funding through #POPARCH)
Reposted by Juan Antonio Rodríguez
The Genomic Kaleidoscope: On the Hidden Dimensions of Within-Species Genomic Diversity academic.oup.com/gbe/article/... 🧬🖥️🧪
November 15, 2025 at 5:00 PM
The Genomic Kaleidoscope: On the Hidden Dimensions of Within-Species Genomic Diversity academic.oup.com/gbe/article/... 🧬🖥️🧪
Reposted by Juan Antonio Rodríguez
O vodka Pascual Veiga é o bum cerebral co que hoxe non contabas.
November 15, 2025 at 12:29 PM
O vodka Pascual Veiga é o bum cerebral co que hoxe non contabas.
Reposted by Juan Antonio Rodríguez
👏 It really shows how powerful meetings can be for sparking ideas and collaborations —and when those turn into joint efforts like this, even greater! Thank you all for this fun adventure!
@mbrasovives.bsky.social @diegoharta.bsky.social @jrotwitguez.bsky.social @theafrogers.bsky.social et al
@mbrasovives.bsky.social @diegoharta.bsky.social @jrotwitguez.bsky.social @theafrogers.bsky.social et al
So, it all started after we organised a symposium at the @official-smbe.bsky.social meeting in 2024, in Puerto Vallarta, Mexico 🇲🇽.
Together with all the speakers (all in the picture), we joined forces to write this Perspective for GBE, summarising the key ideas and results presented there.
(3/n)
Together with all the speakers (all in the picture), we joined forces to write this Perspective for GBE, summarising the key ideas and results presented there.
(3/n)
November 14, 2025 at 4:35 PM
👏 It really shows how powerful meetings can be for sparking ideas and collaborations —and when those turn into joint efforts like this, even greater! Thank you all for this fun adventure!
@mbrasovives.bsky.social @diegoharta.bsky.social @jrotwitguez.bsky.social @theafrogers.bsky.social et al
@mbrasovives.bsky.social @diegoharta.bsky.social @jrotwitguez.bsky.social @theafrogers.bsky.social et al
Reposted by Juan Antonio Rodríguez
Read the whole paper and more information about my research and ongoing projects at:
emiliomarmol.academicwebsite.com
www.cell.com/cell/fulltex...
emiliomarmol.academicwebsite.com
www.cell.com/cell/fulltex...
Emilio Marmol Sanchez | Ancient RNA
Researcher exploring ancient RNA, epigenetics and 3D genomics in extinct and extant species. View my CV, highlights, and contact information.
emiliomarmol.academicwebsite.com
November 14, 2025 at 4:08 PM
Read the whole paper and more information about my research and ongoing projects at:
emiliomarmol.academicwebsite.com
www.cell.com/cell/fulltex...
emiliomarmol.academicwebsite.com
www.cell.com/cell/fulltex...
Reposted by Juan Antonio Rodríguez
🦣🧬🦣🤯💥We are pleased to share our new paper about ancient RNA expression profiles from the Woolly Mammoth, now published in Cell @cellpress.bsky.social
www.cell.com/cell/fulltex...
If you want to know more, read the 🧵 below:
www.cell.com/cell/fulltex...
If you want to know more, read the 🧵 below:
November 14, 2025 at 4:08 PM
🦣🧬🦣🤯💥We are pleased to share our new paper about ancient RNA expression profiles from the Woolly Mammoth, now published in Cell @cellpress.bsky.social
www.cell.com/cell/fulltex...
If you want to know more, read the 🧵 below:
www.cell.com/cell/fulltex...
If you want to know more, read the 🧵 below:
🔊New perspective piece out @genomebiolevol.bsky.social.
"The Genomic Kaleidoscope: On the Hidden Dimensions of Within-Species Genomic Diversity" 💡🌀🌈
doi.org/10.1093/gbe/...
Co-led with @mbrasovives.bsky.social and @diegoharta.bsky.social
Check out our thread! 🧵👇 (1/n)
"The Genomic Kaleidoscope: On the Hidden Dimensions of Within-Species Genomic Diversity" 💡🌀🌈
doi.org/10.1093/gbe/...
Co-led with @mbrasovives.bsky.social and @diegoharta.bsky.social
Check out our thread! 🧵👇 (1/n)
Validate User
doi.org
November 14, 2025 at 9:11 AM
🔊New perspective piece out @genomebiolevol.bsky.social.
"The Genomic Kaleidoscope: On the Hidden Dimensions of Within-Species Genomic Diversity" 💡🌀🌈
doi.org/10.1093/gbe/...
Co-led with @mbrasovives.bsky.social and @diegoharta.bsky.social
Check out our thread! 🧵👇 (1/n)
"The Genomic Kaleidoscope: On the Hidden Dimensions of Within-Species Genomic Diversity" 💡🌀🌈
doi.org/10.1093/gbe/...
Co-led with @mbrasovives.bsky.social and @diegoharta.bsky.social
Check out our thread! 🧵👇 (1/n)
Reposted by Juan Antonio Rodríguez
We have 🐟 herring pre print!
Our new study reveals that ancient gene flow between Pacific and Atlantic herring played a key role in helping Atlantic herring adapt to the brackish waters of the Baltic Sea.
www.biorxiv.org/content/10.1...
Our new study reveals that ancient gene flow between Pacific and Atlantic herring played a key role in helping Atlantic herring adapt to the brackish waters of the Baltic Sea.
www.biorxiv.org/content/10.1...
www.biorxiv.org
November 7, 2025 at 9:13 PM
We have 🐟 herring pre print!
Our new study reveals that ancient gene flow between Pacific and Atlantic herring played a key role in helping Atlantic herring adapt to the brackish waters of the Baltic Sea.
www.biorxiv.org/content/10.1...
Our new study reveals that ancient gene flow between Pacific and Atlantic herring played a key role in helping Atlantic herring adapt to the brackish waters of the Baltic Sea.
www.biorxiv.org/content/10.1...
Reposted by Juan Antonio Rodríguez
Really grateful to see our work featured by @quantamagazine.bsky.social in this piece on the evolution of genome regulation. Huge thanks to @philipcball.bsky.social for such a beautifully written article.
I adored writing this piece. It brings together several of the things preoccupying me right now, like chromatin organization and gene regulation. There's so much more to be said on that. Also, these marine critters look gorgeous.
www.quantamagazine.org/loops-of-dna...
www.quantamagazine.org/loops-of-dna...
Loops of DNA Equipped Ancient Life To Become Complex | Quanta Magazine
New work shows that physical folding of the genome to control genes located far away may have been an early evolutionary development.
www.quantamagazine.org
October 8, 2025 at 8:49 PM
Really grateful to see our work featured by @quantamagazine.bsky.social in this piece on the evolution of genome regulation. Huge thanks to @philipcball.bsky.social for such a beautifully written article.
Reposted by Juan Antonio Rodríguez
Are you interested in microRNAs 🧬 and goats 🐐? We are!!
Then have a look at our preprint on how microRNA mutations segregate worldwide 🌍 in goat populations and the potentially derived consequences of prolonged inbreeding and geographical isolation.
www.biorxiv.org/content/10.1...
Then have a look at our preprint on how microRNA mutations segregate worldwide 🌍 in goat populations and the potentially derived consequences of prolonged inbreeding and geographical isolation.
www.biorxiv.org/content/10.1...
The variability of goat microRNA genes is strongly shaped by functional constraints
Background MicroRNAs (miRNAs) are a type of small non-coding RNAs involved in the post-transcriptional repression of target mRNA transcripts, and responsible for the fine-tuning of numerous molecular ...
www.biorxiv.org
October 3, 2025 at 7:20 AM
Are you interested in microRNAs 🧬 and goats 🐐? We are!!
Then have a look at our preprint on how microRNA mutations segregate worldwide 🌍 in goat populations and the potentially derived consequences of prolonged inbreeding and geographical isolation.
www.biorxiv.org/content/10.1...
Then have a look at our preprint on how microRNA mutations segregate worldwide 🌍 in goat populations and the potentially derived consequences of prolonged inbreeding and geographical isolation.
www.biorxiv.org/content/10.1...
Reposted by Juan Antonio Rodríguez
You can keep on gatekeeping us small fish, but know that we do good science and we will fight to keep publishing our good science. But also note that your gatekeeping has now cost Anais her whole career. If you're an Editor that did this - you kinda did that dude/dudette.
September 15, 2025 at 6:42 PM
You can keep on gatekeeping us small fish, but know that we do good science and we will fight to keep publishing our good science. But also note that your gatekeeping has now cost Anais her whole career. If you're an Editor that did this - you kinda did that dude/dudette.
Reposted by Juan Antonio Rodríguez
I particularly liked this.
"To create a true drug discovery engine, he believes we need half a dozen AlphaFold-level breakthroughs."
I mean, we *could* alternatively just do more science - but hell no, let's assume we just need to throw more AI at it.
"To create a true drug discovery engine, he believes we need half a dozen AlphaFold-level breakthroughs."
I mean, we *could* alternatively just do more science - but hell no, let's assume we just need to throw more AI at it.
September 10, 2025 at 12:27 PM
I particularly liked this.
"To create a true drug discovery engine, he believes we need half a dozen AlphaFold-level breakthroughs."
I mean, we *could* alternatively just do more science - but hell no, let's assume we just need to throw more AI at it.
"To create a true drug discovery engine, he believes we need half a dozen AlphaFold-level breakthroughs."
I mean, we *could* alternatively just do more science - but hell no, let's assume we just need to throw more AI at it.
Reposted by Juan Antonio Rodríguez
🚨 The #SMBE2026 website is live! 🚨
The call for symposia is now open ➡️ smbe2026.org/symposia/
📅 Opens: Sept 1, 2025
📅 Closes: Oct 15, 2025
📢 Results: Nov 3, 2025
We can’t wait to welcome you to beautiful #Copenhagen 🌍✨
@official-smbe.bsky.social
#evolution #science
The call for symposia is now open ➡️ smbe2026.org/symposia/
📅 Opens: Sept 1, 2025
📅 Closes: Oct 15, 2025
📢 Results: Nov 3, 2025
We can’t wait to welcome you to beautiful #Copenhagen 🌍✨
@official-smbe.bsky.social
#evolution #science
Symposia - SMBE 2026 - Copenhagen Denmark
SMBE 2026 Symposia Check deadlines and important dates below. Days Hours Minutes Seconds Conference Symposia We are now accepting proposals for symposium for the 2026 Annual meeting taking place in C...
smbe2026.org
September 3, 2025 at 3:08 PM
🚨 The #SMBE2026 website is live! 🚨
The call for symposia is now open ➡️ smbe2026.org/symposia/
📅 Opens: Sept 1, 2025
📅 Closes: Oct 15, 2025
📢 Results: Nov 3, 2025
We can’t wait to welcome you to beautiful #Copenhagen 🌍✨
@official-smbe.bsky.social
#evolution #science
The call for symposia is now open ➡️ smbe2026.org/symposia/
📅 Opens: Sept 1, 2025
📅 Closes: Oct 15, 2025
📢 Results: Nov 3, 2025
We can’t wait to welcome you to beautiful #Copenhagen 🌍✨
@official-smbe.bsky.social
#evolution #science
Happy to have contributed to this beautiful paper! 🪶
August 26, 2025 at 1:34 PM
Happy to have contributed to this beautiful paper! 🪶
Reposted by Juan Antonio Rodríguez
Please repost at #eseb2025 so people will be more careful.
Hi #eseb2025 folks. Last night my laptopbag was taken /picked pocketed from me at outdoor seating at a restaurant. Close to the conference centre. Please keep your belongings close even in not crowded places. I was with 7 other people and no one saw it happening. cCTV did.
August 20, 2025 at 8:22 AM
Please repost at #eseb2025 so people will be more careful.
Reposted by Juan Antonio Rodríguez
@hologenomics.bsky.social is well represented at this #ESEB2025 week!
Today @hernmoral.bsky.social and @jrotwitguez.bsky.social presented their exciting research!!
#hologenomics
Today @hernmoral.bsky.social and @jrotwitguez.bsky.social presented their exciting research!!
#hologenomics
August 19, 2025 at 1:55 PM
@hologenomics.bsky.social is well represented at this #ESEB2025 week!
Today @hernmoral.bsky.social and @jrotwitguez.bsky.social presented their exciting research!!
#hologenomics
Today @hernmoral.bsky.social and @jrotwitguez.bsky.social presented their exciting research!!
#hologenomics
Reposted by Juan Antonio Rodríguez
Wonderful wrap up for a great symposium #ESEB2025 - thank you to all parcitipants for their high quality presentations, talks and posters (here most of the female contributors, but there were more 😉)
August 19, 2025 at 10:11 PM
Wonderful wrap up for a great symposium #ESEB2025 - thank you to all parcitipants for their high quality presentations, talks and posters (here most of the female contributors, but there were more 😉)
As the father of the baby, I support this. ✨😁
#ESEB2025
#ESEB2025
Navigating #motherhood and academia:
Attending our 1st conference #ESEB2025 as a family with our 10mo baby.
I am disappointed with the organization for not providing childcare for <3yo babies.
Academia should do better for the ✨inclusivity✨ of (lactant) mothers.
See you in P03.148 on thursday!
Attending our 1st conference #ESEB2025 as a family with our 10mo baby.
I am disappointed with the organization for not providing childcare for <3yo babies.
Academia should do better for the ✨inclusivity✨ of (lactant) mothers.
See you in P03.148 on thursday!
📌 Museomics symposium
Claudia Fontsere — Poster P03.148 (Thu)
From almost extinct to rescued? Temporal dynamics of genomic erosion after demographic recovery
Claudia Fontsere — Poster P03.148 (Thu)
From almost extinct to rescued? Temporal dynamics of genomic erosion after demographic recovery
August 18, 2025 at 9:13 AM
As the father of the baby, I support this. ✨😁
#ESEB2025
#ESEB2025
Reposted by Juan Antonio Rodríguez
Happy to share that our Perspective on how genome editing could restore lost diversity and help species adapt to climate or disease is out in @natrevbiodiv.nature.com
We discuss potential, unknowns and risks
tinyurl.com/33nm48vd
Free access here: rdcu.be/ewMBq
#consgen #popgen #Biodiversity
We discuss potential, unknowns and risks
tinyurl.com/33nm48vd
Free access here: rdcu.be/ewMBq
#consgen #popgen #Biodiversity
Genome engineering in biodiversity conservation and restoration - Nature Reviews Biodiversity
This Perspective argues for the use of genome engineering for restoring species genetic diversity and increase species resilience to environmental change. Genome engineering could be combined with tra...
tinyurl.com
July 18, 2025 at 12:23 PM
Happy to share that our Perspective on how genome editing could restore lost diversity and help species adapt to climate or disease is out in @natrevbiodiv.nature.com
We discuss potential, unknowns and risks
tinyurl.com/33nm48vd
Free access here: rdcu.be/ewMBq
#consgen #popgen #Biodiversity
We discuss potential, unknowns and risks
tinyurl.com/33nm48vd
Free access here: rdcu.be/ewMBq
#consgen #popgen #Biodiversity
Reposted by Juan Antonio Rodríguez
How to represent genomes in 3D?
In this paper (and video), we propose Geometric Diagrams of Genomes (GDG)—a visual grammar that aims at emulating the effect ribbon diagrams (Richardson et al 1981) had in protein structural biology. Time will tell.😅
👉🏼 genomebiology.biomedcentral.com/articles/10....
In this paper (and video), we propose Geometric Diagrams of Genomes (GDG)—a visual grammar that aims at emulating the effect ribbon diagrams (Richardson et al 1981) had in protein structural biology. Time will tell.😅
👉🏼 genomebiology.biomedcentral.com/articles/10....
June 27, 2025 at 8:13 AM
How to represent genomes in 3D?
In this paper (and video), we propose Geometric Diagrams of Genomes (GDG)—a visual grammar that aims at emulating the effect ribbon diagrams (Richardson et al 1981) had in protein structural biology. Time will tell.😅
👉🏼 genomebiology.biomedcentral.com/articles/10....
In this paper (and video), we propose Geometric Diagrams of Genomes (GDG)—a visual grammar that aims at emulating the effect ribbon diagrams (Richardson et al 1981) had in protein structural biology. Time will tell.😅
👉🏼 genomebiology.biomedcentral.com/articles/10....
Reposted by Juan Antonio Rodríguez
🚀 En route to #ICCB2025!
Excited to be part of Symposium 122: "Applying Genomics to Biodiversity Conservation"
📅 Wednesday, June 18 | 🕑 2:00 PM | 📍 Room M9
Joining forces with Carolyn Hogg, Christina Hwilson & Laura Bertola. See you there! #ConservationGenomics #ConsGen
Excited to be part of Symposium 122: "Applying Genomics to Biodiversity Conservation"
📅 Wednesday, June 18 | 🕑 2:00 PM | 📍 Room M9
Joining forces with Carolyn Hogg, Christina Hwilson & Laura Bertola. See you there! #ConservationGenomics #ConsGen
June 13, 2025 at 4:44 PM
🚀 En route to #ICCB2025!
Excited to be part of Symposium 122: "Applying Genomics to Biodiversity Conservation"
📅 Wednesday, June 18 | 🕑 2:00 PM | 📍 Room M9
Joining forces with Carolyn Hogg, Christina Hwilson & Laura Bertola. See you there! #ConservationGenomics #ConsGen
Excited to be part of Symposium 122: "Applying Genomics to Biodiversity Conservation"
📅 Wednesday, June 18 | 🕑 2:00 PM | 📍 Room M9
Joining forces with Carolyn Hogg, Christina Hwilson & Laura Bertola. See you there! #ConservationGenomics #ConsGen
Reposted by Juan Antonio Rodríguez
if the wheels had come off this thing any faster it'd be a Cybertruck
June 5, 2025 at 8:21 PM
if the wheels had come off this thing any faster it'd be a Cybertruck
Reposted by Juan Antonio Rodríguez
Por lo menos en los años 20 antes del nazismo y las guerras hubo unas vanguardias, un terremoto cultural del copón bendito.
Nosotros nos vamos a comer lo mismo 100 años después pero con reguetón y libros escritos por influencers.
Este siglo es una reputísima mierda pinchá en un palo.
Nosotros nos vamos a comer lo mismo 100 años después pero con reguetón y libros escritos por influencers.
Este siglo es una reputísima mierda pinchá en un palo.
May 18, 2025 at 12:33 PM
Por lo menos en los años 20 antes del nazismo y las guerras hubo unas vanguardias, un terremoto cultural del copón bendito.
Nosotros nos vamos a comer lo mismo 100 años después pero con reguetón y libros escritos por influencers.
Este siglo es una reputísima mierda pinchá en un palo.
Nosotros nos vamos a comer lo mismo 100 años después pero con reguetón y libros escritos por influencers.
Este siglo es una reputísima mierda pinchá en un palo.
Reposted by Juan Antonio Rodríguez
devastated to discover Cheddar Man was lactose intolerant
May 13, 2025 at 6:39 AM
devastated to discover Cheddar Man was lactose intolerant
Reposted by Juan Antonio Rodríguez
I’m very excited to share our work on the early evolution of animal regulatory genome architecture - the main project of my postdoc, carried out across two wonderful and inspirational labs of @arnausebe.bsky.social and @mamartirenom.bsky.social. www.nature.com/articles/s41...
Chromatin loops are an ancestral hallmark of the animal regulatory genome - Nature
The physical organization of the genome in non-bilaterian animals and their closest unicellular relatives is characterized; comparative analysis shows chromatin looping is a conserved feature of ...
www.nature.com
May 7, 2025 at 3:23 PM
I’m very excited to share our work on the early evolution of animal regulatory genome architecture - the main project of my postdoc, carried out across two wonderful and inspirational labs of @arnausebe.bsky.social and @mamartirenom.bsky.social. www.nature.com/articles/s41...