Lightnews — Scholar-powered news

Juan Antonio Rodríguez

@jrotwitguez.bsky.social

280 followers 490 following 45 posts

MSCA Researcher @ Globe Institute (Copenhagen) A cocktail of 3D genomes 🧬, GWAS, evolution and sprinkles of randomness. Metagenomics and microbial things, lately. 🦠 Reposts with pH under 7, sometimes. 📍 Cedeira sempre, now in 🇩🇰

Posts Media Videos Starter Packs

Pinned

Juan Antonio Rodríguez @jrotwitguez.bsky.social · Feb 12

New paper out! 📄
My first adventures in (ancient) metagenomics. 🦠

“Exploring DNA degradation in situ and in museum storage through genomics and metagenomics” www.nature.com/articles/s42...

Curious about the water color painting (see ALT text)? 🦌

Thread (Bluetorial?) with findings!
🧶👇 (1/n)

Caption by professor B Gronnow.

Water color by Nuka Konrad Godtfredsen (2021). Copyright: The National Museum of Denmark.

"Hunting a herd of swimming caribou from kayak at the site, Aasivissuit, in the early 18th century West Greenland as interpreted by the Greenlandic artist, Nuka Godtfredsen. Through communal drive hunts the Inuit secured large amounts of caribou meat and fat for consumption as well as hide and antler for raw materials and trade. Large heaps of bones from the butchering of the animals piled up as waste in the midden area of the settlement, Three centuries later archaeologists excavated the bones, which were analyzed, including studies of preservation conditions of ancient DNA contained in the bones and soil."

1 19 56

Reposted by Juan Antonio Rodríguez

Iana V. Kim @ianakim.bsky.social · 14h

Really grateful to see our work featured by @quantamagazine.bsky.social in this piece on the evolution of genome regulation. Huge thanks to @philipcball.bsky.social for such a beautifully written article.

Philip Ball @philipcball.bsky.social · 21h

I adored writing this piece. It brings together several of the things preoccupying me right now, like chromatin organization and gene regulation. There's so much more to be said on that. Also, these marine critters look gorgeous.
www.quantamagazine.org/loops-of-dna...

Loops of DNA Equipped Ancient Life To Become Complex | Quanta Magazine

New work shows that physical folding of the genome to control genes located far away may have been an early evolutionary development.

www.quantamagazine.org

2 16 30

Reposted by Juan Antonio Rodríguez

Emilio Mármol Sánchez @marmole6.bsky.social · 6d

Are you interested in microRNAs 🧬 and goats 🐐? We are!!

Then have a look at our preprint on how microRNA mutations segregate worldwide 🌍 in goat populations and the potentially derived consequences of prolonged inbreeding and geographical isolation.

www.biorxiv.org/content/10.1...

The variability of goat microRNA genes is strongly shaped by functional constraints

Background MicroRNAs (miRNAs) are a type of small non-coding RNAs involved in the post-transcriptional repression of target mRNA transcripts, and responsible for the fine-tuning of numerous molecular ...

www.biorxiv.org

1 3

Reposted by Juan Antonio Rodríguez

Dr. Arun Sethuraman @arunsethuraman.bsky.social · 23d

You can keep on gatekeeping us small fish, but know that we do good science and we will fight to keep publishing our good science. But also note that your gatekeeping has now cost Anais her whole career. If you're an Editor that did this - you kinda did that dude/dudette.

1 8

Reposted by Juan Antonio Rodríguez

Philip Ball @philipcball.bsky.social · 28d

I particularly liked this.
"To create a true drug discovery engine, he believes we need half a dozen AlphaFold-level breakthroughs."
I mean, we *could* alternatively just do more science - but hell no, let's assume we just need to throw more AI at it.

1 6 34

Reposted by Juan Antonio Rodríguez

Hernán E. Morales @hernmoral.bsky.social · Sep 3

🚨 The #SMBE2026 website is live! 🚨
The call for symposia is now open ➡️ smbe2026.org/symposia/
📅 Opens: Sept 1, 2025
📅 Closes: Oct 15, 2025
📢 Results: Nov 3, 2025
We can’t wait to welcome you to beautiful #Copenhagen 🌍✨
@official-smbe.bsky.social
#evolution #science

Symposia - SMBE 2026 - Copenhagen Denmark

SMBE 2026 Symposia Check deadlines and important dates below. Days Hours Minutes Seconds Conference Symposia We are now accepting proposals for symposium for the 2026 Annual meeting taking place in C...

smbe2026.org

12 25

Juan Antonio Rodríguez @jrotwitguez.bsky.social · Aug 26

Happy to have contributed to this beautiful paper! 🪶

Clàudia Fontserè @claudiafontsere.bsky.social · Aug 26

This is now published at #MolecularEcology onlinelibrary.wiley.com/doi/10.1111/...

Check it out!

Reposted by Juan Antonio Rodríguez

Lee Hsiang Liow （廖珕庠） @lhliow.bsky.social · Aug 20

Please repost at #eseb2025 so people will be more careful.

Lee Hsiang Liow （廖珕庠） @lhliow.bsky.social · Aug 20

Hi #eseb2025 folks. Last night my laptopbag was taken /picked pocketed from me at outdoor seating at a restaurant. Close to the conference centre. Please keep your belongings close even in not crowded places. I was with 7 other people and no one saw it happening. cCTV did.

2 1

Reposted by Juan Antonio Rodríguez

Center for Evolutionary Hologenomics @hologenomics.bsky.social · Aug 19

@hologenomics.bsky.social is well represented at this #ESEB2025 week!

Today @hernmoral.bsky.social and @jrotwitguez.bsky.social presented their exciting research!!

#hologenomics

1 3

Reposted by Juan Antonio Rodríguez

Aurora Ruiz-Herrera @aruizherrera.bsky.social · Aug 19

Wonderful wrap up for a great symposium #ESEB2025 - thank you to all parcitipants for their high quality presentations, talks and posters (here most of the female contributors, but there were more 😉)

7 19

Juan Antonio Rodríguez @jrotwitguez.bsky.social · Aug 18

As the father of the baby, I support this. ✨😁
#ESEB2025

Clàudia Fontserè @claudiafontsere.bsky.social · Aug 18

Navigating #motherhood and academia:
Attending our 1st conference #ESEB2025 as a family with our 10mo baby.
I am disappointed with the organization for not providing childcare for <3yo babies.
Academia should do better for the ✨inclusivity✨ of (lactant) mothers.
See you in P03.148 on thursday!

Hernán E. Morales @hernmoral.bsky.social · Aug 17

📌 Museomics symposium
Claudia Fontsere — Poster P03.148 (Thu)
From almost extinct to rescued? Temporal dynamics of genomic erosion after demographic recovery

Reposted by Juan Antonio Rodríguez

Hernán E. Morales @hernmoral.bsky.social · Jul 18

Happy to share that our Perspective on how genome editing could restore lost diversity and help species adapt to climate or disease is out in @natrevbiodiv.nature.com
We discuss potential, unknowns and risks
tinyurl.com/33nm48vd
Free access here: rdcu.be/ewMBq
#consgen #popgen #Biodiversity

Genome engineering in biodiversity conservation and restoration - Nature Reviews Biodiversity

This Perspective argues for the use of genome engineering for restoring species genetic diversity and increase species resilience to environmental change. Genome engineering could be combined with tra...

tinyurl.com

1 9 36

Reposted by Juan Antonio Rodríguez

Marc A. Marti-Renom @mamartirenom.bsky.social · Jun 27

How to represent genomes in 3D?

In this paper (and video), we propose Geometric Diagrams of Genomes (GDG)—a visual grammar that aims at emulating the effect ribbon diagrams (Richardson et al 1981) had in protein structural biology. Time will tell.😅

👉🏼 genomebiology.biomedcentral.com/articles/10....

2 19 44

Reposted by Juan Antonio Rodríguez

Hernán E. Morales @hernmoral.bsky.social · Jun 13

🚀 En route to #ICCB2025!
Excited to be part of Symposium 122: "Applying Genomics to Biodiversity Conservation"
📅 Wednesday, June 18 | 🕑 2:00 PM | 📍 Room M9
Joining forces with Carolyn Hogg, Christina Hwilson & Laura Bertola. See you there! #ConservationGenomics #ConsGen

2 12 42

Reposted by Juan Antonio Rodríguez

Deontological Warfare But She's A Skeleton Or Something @clockworklady.bsky.social · Jun 5

if the wheels had come off this thing any faster it'd be a Cybertruck

96 1.9K 12K

Reposted by Juan Antonio Rodríguez

HermanosPelaez @pelaez.bsky.social · May 18

Por lo menos en los años 20 antes del nazismo y las guerras hubo unas vanguardias, un terremoto cultural del copón bendito.
Nosotros nos vamos a comer lo mismo 100 años después pero con reguetón y libros escritos por influencers.
Este siglo es una reputísima mierda pinchá en un palo.

34 220 880

Reposted by Juan Antonio Rodríguez

depths of wikipedia @depthsofwikipedia.bsky.social · May 13

devastated to discover Cheddar Man was lactose intolerant

Analysis of Cheddar Man's nuclear DNA indicates that he was a typical member of the Western European hunter-gatherer population at the time, with a most likely phenotype of blue-green eyes, dark brown or black hair, and dark or dark-to-black skin, with no genetic adaption for lactase persistence into adulthood

31 220 1.5K

Juan Antonio Rodríguez @jrotwitguez.bsky.social · May 7

Congrats Iana and the team! Super interesting work! 🥳👏

1 4

Reposted by Juan Antonio Rodríguez

Iana V. Kim @ianakim.bsky.social · May 7

I’m very excited to share our work on the early evolution of animal regulatory genome architecture - the main project of my postdoc, carried out across two wonderful and inspirational labs of @arnausebe.bsky.social and @mamartirenom.bsky.social. www.nature.com/articles/s41...

Chromatin loops are an ancestral hallmark of the animal regulatory genome - Nature

The physical organization of the genome in non-bilaterian animals and their closest unicellular relatives is characterized; comparative analysis shows chromatin looping is a conserved feature of ...

www.nature.com

13 120 270

Juan Antonio Rodríguez @jrotwitguez.bsky.social · May 2

Haha… 🍔🦣 the “McMammoth with cheese” is the final goal.

Reposted by Juan Antonio Rodríguez

Juan Antonio Rodríguez @jrotwitguez.bsky.social · Apr 24

With @hologenomics.bsky.social, we sampled each step of the process to see how microbial communities evolve.

Spoiler alert: Even in a stable, well-behaved system, we found some surprises... 👀 (3/7)

1 2 3

Reposted by Juan Antonio Rodríguez

Clàudia Fontserè @claudiafontsere.bsky.social · May 1

I'll be teaching in the SIBE Summer School in Ferrara, from the 7th to 11th of September.
Great place to learn about PopGen, comparative genomics and ✨Conservation Genomics✨
🚨Deadline to apply: 11th of May🚨
sites.google.com/view/sibesum...

See you there!

SIBE summer school

SIBE SUMMER SCHOOL 2025 7th − 11th September 2025 FERRARA (ITALY) Overview The analysis of genomic data has become increasingly feasible, even in non-model organisms, thanks to the “omics” revolution...

sites.google.com

8 8

Reposted by Juan Antonio Rodríguez

Svetlana Ugarcina Perovic @svetlanaup.bsky.social · Apr 30

New #MicrobiomeDigest: microbiomedigest.com/2025/04/30/a...

•Herrgårds cheese @jrotwitguez.bsky.social‬
•Asian Skin Microbiome Program @cherrychengchenli.bsky.social ‬
•long-read assemblers @floriantrigodet.bsky.social
•argNorm @vedanthramji.bsky.social

CU next week at @microbiomevif.bsky.social!

April 30, 2025

See you next week at MVIF! Skin microbiome Large-scale skin metagenomics reveals extensive prevalence, coordination, and functional adaptation of skin microbiome dermotypes across body sites – Che…

microbiomedigest.com

5 4

Reposted by Juan Antonio Rodríguez

Jorge García @jgarcia-cal.bsky.social · Apr 24

I am delighted to share with you some new insights into the selection processes that shaped the Spanish population!

This work has been led by @ebosch1972.bsky.social @francesccalafell.bsky.social ( @upf.edu ) in collaboration with Rafael de Cid ( @igtp.bsky.social ) and @sabiagini.bsky.social

⬇️⬇️⬇️

Inferring past demography and genetic adaptation in Spain using the GCAT cohort - Scientific Reports

Scientific Reports - Inferring past demography and genetic adaptation in Spain using the GCAT cohort

www.nature.com

1 12 17

Juan Antonio Rodríguez @jrotwitguez.bsky.social · Apr 24

🎯 Finally, we tried something new: using K-mer counting on raw sequencing reads + Hill numbers to predict microbiome variability across trials.
This could help detect contamination early and stop batches before spoilage. (7/7)

Juan Antonio Rodríguez @jrotwitguez.bsky.social · Apr 24

😬 Clostridium tyrobutyricum—the culprit behind “baby vomit” off-flavor (butyric acid)—was completely absent after microfiltration. (The holes in the picture? That’s them.) (6/7)

1 2