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Reposted by Jorge García

David Castellano @castellanoed.bsky.social · 1d

Working link: academic.oup.com/mbe/advance-...

Interpreting supervised machine learning inferences in population genomics using haplotype matrix permutations

Abstract. Supervised machine learning methods, such as convolutional neural networks (CNNs), that use haplotype matrices as input data have become powerful

academic.oup.com

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Reposted by Jorge García

Ana Ignatieva @anaignatieva.bsky.social · 5d

Delighted that our paper about the distribution of genomic spans of clades/edges in genealogies (ARGs), and using this for detecting inversions and other SVs (and other phenomena that cause local disruption of recombination) is out in MBE academic.oup.com/mbe/article/... (1/n)

The Length of Haplotype Blocks and Signals of Structural Variation in Reconstructed Genealogies

Abstract. Recent breakthroughs have enabled the accurate inference of large-scale genealogies. Through modelling the impact of recombination on the correla

academic.oup.com

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Reposted by Jorge García

bioRxiv Evolutionary Biology @biorxiv-evobio.bsky.social · 7d

A maternal-fetal PIEZO1 incompatibility as a barrier to Neanderthal-modern human admixture https://www.biorxiv.org/content/10.1101/2025.09.29.679417v1

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Reposted by Jorge García

bioRxiv Evolutionary Biology @biorxiv-evobio.bsky.social · 7d

Bridging forward-in-time and coalescent simulations using pyslim https://www.biorxiv.org/content/10.1101/2025.09.30.679676v1

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Reposted by Jorge García

POPGROUP59 @popgroup2026.bsky.social · 9d

Exciting news!
The next #PopGroup meeting will take place in Lille 🍟, France, 7–9 January 2026 – just 1 hour by train from London, Brussels, and Paris.

This year, PopGroup will also host ALPHY, the annual meeting of Evolutionary Genomics.

More info: populationgeneticsgroup.org.uk

See you there !

Population Genetics group 59

populationgeneticsgroup.org.uk

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Reposted by Jorge García

IHPST | University of Toronto @ihpst-uoft.bsky.social · 9d

📢 Register for the Dialectical Biologist anniversary event to explore different perspectives on the intersections of biology, philosophy, and politics. Available in-person or online. Reserve your spot today!

Dialectical Biology Today: Legacies of Richard Lewontin -- Conference Registration

A hybrid conference on the 40th anniversary of Richard Levins and Richard Lewontin's The Dialectical Biologist, to be held in person at the University of Toronto and online via zoom. Registration is…

docs.google.com

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Reposted by Jorge García

Chris Stringer @chrisbstringer.bsky.social · 13d

My explainer about the Yunxian 2 study

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Reposted by Jorge García

Robin Hofmeister @rjhfmstr.bsky.social · 12d

🚨 New preprint out!
We reconstructed parental haplotypes in >440k individuals (UK & Estonian biobanks) to estimate assortative mating directly in the parental generation.
This reveals intensified assortment in recent generations.
www.biorxiv.org/content/10.1...

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Reposted by Jorge García

Stefan Ruhl 🦷💧🦠 @spit-lab.bsky.social · 12d

What have 🦷🦷 #TEETH 🦷🦷, 🥛 #MILK 🥛, and💧💧 #SALIVA 💧💧to do with each other? Ask PetarPajic, Luane Landau, and Omer Gokcumen @gokcumenlab.bsky.social ❗️

academic.oup.com/gbe/article-...

Saliva Protein Genes in Humans were Shaped During Primate Evolution

Abstract. Genes within the secretory calcium-binding phosphoprotein locus diversified along with the formation of a calcified skeleton in vertebrates, the

academic.oup.com

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Jorge García @jgarcia-cal.bsky.social · 14d

Something that I was thinking during the SMBE congress. Expected a high variance between methods to detect introgression, but so high?

Wondering if there are significant differences between methods using human and archaic outgroups

bioRxiv Evolutionary Biology @biorxiv-evobio.bsky.social · 14d

Comparing Neanderthal introgression maps reveals core agreement but substantial heterogeneity https://www.biorxiv.org/content/10.1101/2025.09.23.678138v1

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Reposted by Jorge García

Charikleia Karageorgiou (Clio) @evobioclio.bsky.social · 15d

DNA shape and epigenomics distinguish the mechanistic origin of human genomic structural variations

The recent advent of long-read whole genome sequencing has enabled us to create an accurate telomere-to-telomere reference genome, construct pangenome graphs, and compile precise catalogs of genomic s...

www.biorxiv.org

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Reposted by Jorge García

Dr. Arun Sethuraman @arunsethuraman.bsky.social · 17d

De-extinction be like.

Oded Rechavi @odedrechavi.bsky.social · 17d

CRISPR is amazing

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Reposted by Jorge García

Sasha Gusev @sashagusevposts.bsky.social · 18d

Massive sibling regression study finds that human traits are largely environmentally driven (average heritability = 0.3)

Within-family heritability estimates for behavioural and disease phenotypes from 500,000 sibling pairs of diverse ancestries

Quantification of the direct effect of genetic variation on human behavioural traits is important for understanding between-individual variation in socio-economic and health outcomes but estimates of ...

www.medrxiv.org

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Reposted by Jorge García

Konrad @konradjk.bsky.social · 20d

A project many years in the process, we’re pleased to present our work on multi-ancestry meta-analysis across a boatload of traits in the UK Biobank: www.nature.com/articles/s41...

Pan-UK Biobank genome-wide association analyses enhance discovery and resolution of ancestry-enriched effects - Nature Genetics

Genome-wide analyses for 7,266 traits leveraging data from several genetic ancestry groups in UK Biobank identify new associations and enhance resources for interpreting risk variants across diverse p...

www.nature.com

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Reposted by Jorge García

Torsten Günther @trstngnthr.bsky.social · 21d

I have funding for a 2-year dry-lab postdoc to join our team @humanevouu.bsky.social 🧪 (Deadline Oct 21st)

The project will utilize modern and #aDNA data from humans and sheep to study environmental adaptation (including method development and simulations).

Please share!
www.uu.se/en/about-uu/...

Postdoctoral position in Population Genomics - Uppsala University

Postdoctoral position in Population Genomics, Department of Organismal Biology, Uppsala University

www.uu.se

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Reposted by Jorge García

Jeffrey Ross-Ibarra @jrossibarra.bsky.social · 22d

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Reposted by Jorge García

Jas Rees @jasminrees.bsky.social · 22d

1/ So pleased to share our paper on genetic adaptation to micronutrients in humans! Our biggest conclusion? Trace minerals in the diet have shaped human evolution far more than previously appreciated 🧬🌍👇
www.cell.com/ajhg/fulltex...

https://www.cell.com/ajhg/fulltext/S0002-9297(25)00315-5

t.co

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Reposted by Jorge García

Pedro @hjorvik.bsky.social · 23d

I totally recommend this position on @trstngnthr.bsky.social lab. Great place to do science, and amazing people to do it with! #aDNA 🧪 www.uu.se/en/about-uu/...

Postdoctoral position in Population Genomics - Uppsala University

Postdoctoral position in Population Genomics, Department of Organismal Biology, Uppsala University

www.uu.se

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Reposted by Jorge García

David Serrano @ddserrano.bsky.social · 24d

ORGULLO de país 🇵🇸

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Reposted by Jorge García

EvolDir @evoldir.bsky.social · 25d

PhD scholarship in Palaeogenomics and Bioinformatics at DTU Health Tech, Denmark. Focus on genomic analyses of degraded DNA. Apply by 24 October 2025. Details: tinyurl.com/BioExtPhD #phd

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Reposted by Jorge García

Graciela Cabana @gscabana.bsky.social · 26d

If you are post-PhD 🎓 and interested in biological anthropology 🧬🦠🦴💀, consider becoming a "Faculty Scholar" in the AABA IDEAS Program!

IDEAS = Increasing Diversity in Evolutionary Biological Anthropology

Check out the link below 👇

The IDEAS Program - AABA

AABA 2026 IDEAS PROGRAM The AABA IDEAS Program provides a team, a space, and a suite of activities to engage issues of scholarship, professional preparation, […]

bioanth.org

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Reposted by Jorge García

Mick Westbury @mick2474.bsky.social · 26d

☠️🧬 2-yr Postdoc in in Genomic Simulations and Extinction Risk Modelling!
Let's figure out the Genomic signs of Extinction @DTU in Denmark.

Start: Feb 2026 (flexible)
Application deadline: 24 Oct 2025

For details click here: tinyurl.com/BioExtPD

Reposts appreciated 😁

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Reposted by Jorge García

Yun S. Song @yun-s-song.bsky.social · 28d

SINGER, our ARG inference method, is finally published and freely available online:

doi.org/10.1038/s415...

It was a long journey – 16 months from initial submission to acceptance. Is it just me, or has peer review gotten more arduous lately? 4+ rounds of review isn't so unusual these days...

Robust and accurate Bayesian inference of genome-wide genealogies for hundreds of genomes - Nature Genetics

SINGER is a method for creating ancestral recombination graphs to understand the genealogical history of genomes. The method has increased speed, and thus scalability, without sacrificing accuracy.

doi.org

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Reposted by Jorge García

Aida Andres @aidaandres.bsky.social · 28d

Jasmin Rees PhD chapter as a paper just out at the AJHG @ajhgnews.bsky.social, with Sergi Castellano, who first envisioned the study. Jas investigated signatures of human local genetic adaptation in hundreds of micronutrient-associated genes.

The American Journal of Human Genetics @ajhgnews.bsky.social · 28d

📣New from @aidaandres.bsky.social & co
📄Global impact of micronutrients in modern human evolution

Global impact of micronutrients in modern human evolution

In this study, Rees et al. evaluate the role of dietary micronutrients in driving local genetic adaptation and population differentiation in humans. The authors find evidence that micronutrient-associ...

www.cell.com

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Reposted by Jorge García

Maud Tenaillon @maudtenaillon.bsky.social · 29d

📢 Postdoc Opportunity – Université Paris-Saclay
🌾🧬💻 Reproductive isolation between crops and their wild relatives
Candidates with PhD in evolutionary genomics & programming skills.
👉 Full description & how to apply: [https://moulon.inrae.fr/en/]
#Postdoc #EvolutionaryGenomics #Speciation

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