Kasper D Hansen
@kasperdhansen.bsky.social
Professor @ JHU, statistical genomics, www.hansenlab.org
How about porting Linux to Rust?
February 4, 2026 at 5:10 PM
How about porting Linux to Rust?
Reposted by Kasper D Hansen
I wrote this song on Saturday, recorded it yesterday and released it to you today in response to the state terror being visited on the city of Minneapolis. It’s dedicated to the people of Minneapolis, our innocent immigrant neighbors and in memory of Alex Pretti and Renee Good.
Stay free
Stay free
Bruce Springsteen - Streets Of Minneapolis (Official Audio)
YouTube video by Bruce Springsteen
youtu.be
January 28, 2026 at 5:02 PM
I wrote this song on Saturday, recorded it yesterday and released it to you today in response to the state terror being visited on the city of Minneapolis. It’s dedicated to the people of Minneapolis, our innocent immigrant neighbors and in memory of Alex Pretti and Renee Good.
Stay free
Stay free
I have not tested it. I strongly think action=error should be default.
January 6, 2026 at 3:32 PM
I have not tested it. I strongly think action=error should be default.
Reposted by Kasper D Hansen
Glad to share our benchmark study in Genome Biology on highly variable gene (HVG) selection methods for single-cell RNA-seq. We show that a hybrid strategy performs best, now implemented in the mixhvg R package. rdcu.be/eUfjt
A systematic evaluation of highly variable gene selection methods for single-cell RNA-sequencing
rdcu.be
December 19, 2025 at 10:21 PM
Glad to share our benchmark study in Genome Biology on highly variable gene (HVG) selection methods for single-cell RNA-seq. We show that a hybrid strategy performs best, now implemented in the mixhvg R package. rdcu.be/eUfjt
Reposted by Kasper D Hansen
Gift link, probably the funniest thing the Wall Street Journal has done this year.
We Let AI Run Our Office Vending Machine. It Lost Hundreds of Dollars.
An AI agent ran a snack operation in the WSJ newsroom. It gave away a free PlayStation, ordered a live fish—and taught us lessons about the future of AI.
www.wsj.com
December 18, 2025 at 3:48 PM
Gift link, probably the funniest thing the Wall Street Journal has done this year.
Reposted by Kasper D Hansen
This is shocking stuff. John Quackenbush has been brilliant since forever. www.statnews.com/2025/12/05/r...
His lab was humming with discovery. After one year under Trump, it’s almost silent
John Quackenbush built a lab that is at the forefront of human genetics research and bioinformatics. Trump administration cuts have put it in danger of collapse.
www.statnews.com
December 10, 2025 at 7:37 AM
This is shocking stuff. John Quackenbush has been brilliant since forever. www.statnews.com/2025/12/05/r...
Reposted by Kasper D Hansen
This is real x.com/grok/status/.... Yangtze record swim times but in LLM form
November 20, 2025 at 1:58 PM
This is real x.com/grok/status/.... Yangtze record swim times but in LLM form
Reposted by Kasper D Hansen
Oops. Ooooooooooooops.
I do hope that nobody has been given or denied a job/promotion based on their SpringerNature citation counts in the past 15 years.
arxiv.org/pdf/2511.01675
h/t @nathlarigaldie.bsky.social
I do hope that nobody has been given or denied a job/promotion based on their SpringerNature citation counts in the past 15 years.
arxiv.org/pdf/2511.01675
h/t @nathlarigaldie.bsky.social
November 7, 2025 at 2:02 PM
Oops. Ooooooooooooops.
I do hope that nobody has been given or denied a job/promotion based on their SpringerNature citation counts in the past 15 years.
arxiv.org/pdf/2511.01675
h/t @nathlarigaldie.bsky.social
I do hope that nobody has been given or denied a job/promotion based on their SpringerNature citation counts in the past 15 years.
arxiv.org/pdf/2511.01675
h/t @nathlarigaldie.bsky.social
Reposted by Kasper D Hansen
Will definitely include this example in my next talk on how to name files!
✅ Full marks for "make it easy to guess what the heck something is, based on it name".
✅ Full marks for "make it easy to guess what the heck something is, based on it name".
Genuinely delighted to download a PhD thesis from a university repository where the author has neglected to remove the words "BITCH THIS IS YOUR THESIS" from the filename.
October 31, 2025 at 8:46 PM
Will definitely include this example in my next talk on how to name files!
✅ Full marks for "make it easy to guess what the heck something is, based on it name".
✅ Full marks for "make it easy to guess what the heck something is, based on it name".
Reposted by Kasper D Hansen
🚀 Bioconductor 3.22 is released!
Thanks to all developers and community members for contributing to the project!
🔗 Please see the full release announcement here: bioconductor.org/news/bioc_3_...
Thanks to all developers and community members for contributing to the project!
🔗 Please see the full release announcement here: bioconductor.org/news/bioc_3_...
Bioconductor - Bioconductor 3.22 Released
The Bioconductor project aims to develop and share open source software for precise and repeatable analysis of biological data. We foster an inclusive and collaborative community of developers and…
bioconductor.org
October 31, 2025 at 7:56 AM
🚀 Bioconductor 3.22 is released!
Thanks to all developers and community members for contributing to the project!
🔗 Please see the full release announcement here: bioconductor.org/news/bioc_3_...
Thanks to all developers and community members for contributing to the project!
🔗 Please see the full release announcement here: bioconductor.org/news/bioc_3_...
Reposted by Kasper D Hansen
We are hiring for a PhD-level Staff Scientist to join our teams in the Translational Neuroscience Division @lieberinstitute.bsky.social. This is an exciting opportunity to work at the intersection of human 🧠 neuroanatomy and molecular neuroscience
recruiting.paylocity.com/recruiting/j...
recruiting.paylocity.com/recruiting/j...
Lieber Institute For Brain Development - Staff Scientist I, Translational Neuroscience
A little about us:The Lieber Institute for Brain Development (LIBD) was established in 2010 to plot a new course in biomedical research that would change the lives of individuals affected with develop...
recruiting.paylocity.com
October 29, 2025 at 4:03 PM
We are hiring for a PhD-level Staff Scientist to join our teams in the Translational Neuroscience Division @lieberinstitute.bsky.social. This is an exciting opportunity to work at the intersection of human 🧠 neuroanatomy and molecular neuroscience
recruiting.paylocity.com/recruiting/j...
recruiting.paylocity.com/recruiting/j...
Yes, that is weird. I for one would rank NAR above Nature Communications if we just focus on journal name.
October 28, 2025 at 2:46 PM
Yes, that is weird. I for one would rank NAR above Nature Communications if we just focus on journal name.
Reposted by Kasper D Hansen
This 1980s anti-drug ad, but about screen time
a close up of a young man 's face with headphones on .
ALT: a close up of a young man 's face with headphones on .
media.tenor.com
October 24, 2025 at 2:11 PM
This 1980s anti-drug ad, but about screen time
Reposted by Kasper D Hansen
Today at #ASHG25 I will talk about the work of a talented graduate student Dev Raj Bhattarai on cell type-specific isoform expression in Alzheimer's disease at the @nanoporetech.com Education Session (12pm Rm 153). Dev will also present his work today at poster 9228T.
October 16, 2025 at 12:30 PM
Today at #ASHG25 I will talk about the work of a talented graduate student Dev Raj Bhattarai on cell type-specific isoform expression in Alzheimer's disease at the @nanoporetech.com Education Session (12pm Rm 153). Dev will also present his work today at poster 9228T.
Today at #ASHG2025 Adam Davidovich will talk about our work on inheritance of DNA methylation patterns in mice with some interesting biology, including (to our knowledge) the first paramutation naturally occurring in mammals.
Room 210C at 11am.
Room 210C at 11am.
October 16, 2025 at 11:50 AM
Today at #ASHG2025 Adam Davidovich will talk about our work on inheritance of DNA methylation patterns in mice with some interesting biology, including (to our knowledge) the first paramutation naturally occurring in mammals.
Room 210C at 11am.
Room 210C at 11am.
It’s the time of the year where 98% of my feed will become posts from @michaelhoffman.bsky.social on ASHG
October 14, 2025 at 9:47 PM
It’s the time of the year where 98% of my feed will become posts from @michaelhoffman.bsky.social on ASHG
Reposted by Kasper D Hansen
New tool "bwt-svg" for making illustrations of the BWT and the many auxiliary arrays and other structures related to it. Pyodide-based no-installation-necessary interface here: benlangmead.github.io/bwt-svg/. (H/t to @robert.bio for pointing me to pyodide!) Full repo: github.com/benlangmead/....
October 14, 2025 at 8:48 PM
New tool "bwt-svg" for making illustrations of the BWT and the many auxiliary arrays and other structures related to it. Pyodide-based no-installation-necessary interface here: benlangmead.github.io/bwt-svg/. (H/t to @robert.bio for pointing me to pyodide!) Full repo: github.com/benlangmead/....
Reposted by Kasper D Hansen
Looking forward to presenting duoNovo at ASHG this week.
We use long-read sequencing to detect de novo variants without having to sequence both parents. It's conceptually straightforward, and performs very accurately among variants likely to be clinically relevant.
www.medrxiv.org/content/10.1...
We use long-read sequencing to detect de novo variants without having to sequence both parents. It's conceptually straightforward, and performs very accurately among variants likely to be clinically relevant.
www.medrxiv.org/content/10.1...
Identification of de novo variants from parent-proband duos via long-read sequencing
While de novo variants cause many Mendelian disorders, their detection currently requires sequencing of the proband and both biological parents. This is not feasible when only one parent is available,...
www.medrxiv.org
October 11, 2025 at 7:33 PM
Looking forward to presenting duoNovo at ASHG this week.
We use long-read sequencing to detect de novo variants without having to sequence both parents. It's conceptually straightforward, and performs very accurately among variants likely to be clinically relevant.
www.medrxiv.org/content/10.1...
We use long-read sequencing to detect de novo variants without having to sequence both parents. It's conceptually straightforward, and performs very accurately among variants likely to be clinically relevant.
www.medrxiv.org/content/10.1...
Reposted by Kasper D Hansen
RcppArmadillo 15 CRAN Transition: Offering Office Hours
Offering office hours to help in updating #rstats CRAN packages to RcppArmadillo 15.0.2 given CRAN 'Deadlines' for a number of the reverse-dependency packages. Details and booking link at blog post.
dirk.eddelbuettel.com/blog/2025/10...
Offering office hours to help in updating #rstats CRAN packages to RcppArmadillo 15.0.2 given CRAN 'Deadlines' for a number of the reverse-dependency packages. Details and booking link at blog post.
dirk.eddelbuettel.com/blog/2025/10...
October 10, 2025 at 2:34 PM
RcppArmadillo 15 CRAN Transition: Offering Office Hours
Offering office hours to help in updating #rstats CRAN packages to RcppArmadillo 15.0.2 given CRAN 'Deadlines' for a number of the reverse-dependency packages. Details and booking link at blog post.
dirk.eddelbuettel.com/blog/2025/10...
Offering office hours to help in updating #rstats CRAN packages to RcppArmadillo 15.0.2 given CRAN 'Deadlines' for a number of the reverse-dependency packages. Details and booking link at blog post.
dirk.eddelbuettel.com/blog/2025/10...
Amazing opportunity for help if you're using RcppArmadillo in a CRAN package.
October 10, 2025 at 2:42 PM
Amazing opportunity for help if you're using RcppArmadillo in a CRAN package.
Thanks for posting. This was an amazing read.
October 9, 2025 at 1:35 AM
Thanks for posting. This was an amazing read.
This is an important limitation and something we should absolutely work on solving.
September 25, 2025 at 1:42 PM
This is an important limitation and something we should absolutely work on solving.
I enjoyed reading the Introduction.
Despite the fact that the cover features neither a dragon, nor a spaceship, I have ordered a copy.
Despite the fact that the cover features neither a dragon, nor a spaceship, I have ordered a copy.
September 18, 2025 at 4:06 PM
I enjoyed reading the Introduction.
Despite the fact that the cover features neither a dragon, nor a spaceship, I have ordered a copy.
Despite the fact that the cover features neither a dragon, nor a spaceship, I have ordered a copy.
How can we know if it is worth reading without seeing the cover? I hope it has either a dragon or a space ship.
www.penny-arcade.com/comic/2022/0...
www.penny-arcade.com/comic/2022/0...
Books And Their Covers - Penny Arcade
Videogaming-related online strip by Mike Krahulik and Jerry Holkins. Includes news and commentary.
www.penny-arcade.com
August 20, 2025 at 1:38 PM
How can we know if it is worth reading without seeing the cover? I hope it has either a dragon or a space ship.
www.penny-arcade.com/comic/2022/0...
www.penny-arcade.com/comic/2022/0...