@katammp.bsky.social
Computational microbiologist working with antimicrobial resistance. Department of Computation, University of Turku
Reposted
Our latest article examines the sulfonamide resistance gene sul4. By using long-read metagenomics and methylation patterns, we show that sul4 appears in diverse genetic contexts and hosts, expanding our understanding of its environmental distribution.
doi.org/10.1128/spec...
#AntibioticResistance
doi.org/10.1128/spec...
#AntibioticResistance
Sulfonamide resistance gene sul4 is hosted by common wastewater sludge bacteria and found in various newly described contexts and hosts | Microbiology Spectrum
Antibiotic resistance is an ancient phenomenon and a common trait of many environmental
bacteria. However, human activities in the post-antibiotic era, coupled with the bacteria’s
ability to exchange ...
doi.org
November 19, 2025 at 2:18 PM
Our latest article examines the sulfonamide resistance gene sul4. By using long-read metagenomics and methylation patterns, we show that sul4 appears in diverse genetic contexts and hosts, expanding our understanding of its environmental distribution.
doi.org/10.1128/spec...
#AntibioticResistance
doi.org/10.1128/spec...
#AntibioticResistance
The Relationship Between Gut Microbiota During Pregnancy and the Level of Postpartum Adiposity - Houttu - 2025 - MicrobiologyOpen - Wiley Online Library onlinelibrary.wiley.com/doi/10.1002/...
The Relationship Between Gut Microbiota During Pregnancy and the Level of Postpartum Adiposity
Postpartum adiposity is associated with maternal α-diversity and several bacterial species. These findings highlight the mediating role of the gut microbiota during pregnancy in influencing the overw...
onlinelibrary.wiley.com
November 13, 2025 at 2:16 PM
The Relationship Between Gut Microbiota During Pregnancy and the Level of Postpartum Adiposity - Houttu - 2025 - MicrobiologyOpen - Wiley Online Library onlinelibrary.wiley.com/doi/10.1002/...
Using wastewater surveillance to investigate community-level differences in antibacterial resistance in a major urban center, USA | Applied and Environmental Microbiology journals-asm-org.ezproxy.utu.fi:2443/doi/10.1128/...
journals-asm-org.ezproxy.utu.fi
November 11, 2025 at 1:21 PM
Using wastewater surveillance to investigate community-level differences in antibacterial resistance in a major urban center, USA | Applied and Environmental Microbiology journals-asm-org.ezproxy.utu.fi:2443/doi/10.1128/...
Reposted
And it is (finally) accepted to be published in Microbiology Spectrum.
Our work on the sulfonamide resistance gene, sul4, is (finally) available as preprint. Thanks to an excellent PhD student Melina Markkanen. Hopefully soon it will be also peer-reviewed and published. After the first desk rejection, we are looking for another journal.
doi.org/10.1101/2025...
doi.org/10.1101/2025...
Sulfonamide resistance gene sul4 is hosted by common wastewater sludge bacteria and found in various newly described contexts and hosts including clinically relevant species
The introduction of the first broad-spectrum antibiotics, sulfonamide drugs fundamentally revolutionized medicine in the 1930s. Shortly after and ever since sulfonamide resistance genes (sul genes) ha...
doi.org
October 25, 2025 at 2:54 PM
And it is (finally) accepted to be published in Microbiology Spectrum.
Nice paper on the temporal dynamics of early infancy. Once again, it was shown that Escherichia & Klebsiella correlate with higher ARG load, and their abundance is in turn negatively associated with Bifidos. Kudos to the authors for the excellent paper!
rdcu.be/eDRPa
rdcu.be/eDRPa
Temporal dynamics and microbial interactions shaping the gut resistome in early infancy
Nature Communications - Here the authors show that antibiotic resistance genes peak in the gut at the age of 6 months, and that beneficial bifidobacteria produce aromatic lactic acids that actively...
rdcu.be
September 3, 2025 at 8:39 AM
Nice paper on the temporal dynamics of early infancy. Once again, it was shown that Escherichia & Klebsiella correlate with higher ARG load, and their abundance is in turn negatively associated with Bifidos. Kudos to the authors for the excellent paper!
rdcu.be/eDRPa
rdcu.be/eDRPa
Reposted
Proud of our group's newest publication!
Variation and prognostic potential of the gut antibiotic resistome in a population-based cohort www.nature.com/articles/s41...
We look at the risks and sociodemographic aspects of antimicrobial resistance, and its association with recent global urbanization and middle-class growth.
We look at the risks and sociodemographic aspects of antimicrobial resistance, and its association with recent global urbanization and middle-class growth.
July 9, 2025 at 12:43 AM
Proud of our group's newest publication!
Reposted
Great thread from @antagomir.bsky.social about our latest collaborative study led by the brilliant @katammp.bsky.social on the antibiotic resistome in a representative Finnish population of n>6,500 individuals and factors associated with carriage.
Link to study: doi.org/10.1038/s414...
Link to study: doi.org/10.1038/s414...
July 15, 2025 at 5:00 PM
Great thread from @antagomir.bsky.social about our latest collaborative study led by the brilliant @katammp.bsky.social on the antibiotic resistome in a representative Finnish population of n>6,500 individuals and factors associated with carriage.
Link to study: doi.org/10.1038/s414...
Link to study: doi.org/10.1038/s414...
Reposted
Read the study: doi.org/10.1038/s414... - /w @katammp.bsky.social @begia.bsky.social Guilhem Sommeria-Klein, Ville Laitinen, Pyry Kantanen, @gmeric.bsky.social @gazollavolpiano.bsky.social Michael Inouye, Rob Knight, Veikko Salomaa, Aki S. Havulinna, Teemu Niiranen, @antagomir.bsky.social
Variation and prognostic potential of the gut antibiotic resistome in the FINRISK 2002 cohort - Nature Communications
Here, in a representative cohort of 7,095 Finnish adults, the authors reveal that gut antibiotic resistance is shaped not only by antibiotic use but also by the microbiome, diet, lifestyle, household ...
doi.org
July 15, 2025 at 2:46 PM
Read the study: doi.org/10.1038/s414... - /w @katammp.bsky.social @begia.bsky.social Guilhem Sommeria-Klein, Ville Laitinen, Pyry Kantanen, @gmeric.bsky.social @gazollavolpiano.bsky.social Michael Inouye, Rob Knight, Veikko Salomaa, Aki S. Havulinna, Teemu Niiranen, @antagomir.bsky.social
Reposted
Variation and prognostic potential of the gut antibiotic resistome in a population-based cohort www.nature.com/articles/s41...
We look at the risks and sociodemographic aspects of antimicrobial resistance, and its association with recent global urbanization and middle-class growth.
We look at the risks and sociodemographic aspects of antimicrobial resistance, and its association with recent global urbanization and middle-class growth.
July 5, 2025 at 9:43 AM
Variation and prognostic potential of the gut antibiotic resistome in a population-based cohort www.nature.com/articles/s41...
We look at the risks and sociodemographic aspects of antimicrobial resistance, and its association with recent global urbanization and middle-class growth.
We look at the risks and sociodemographic aspects of antimicrobial resistance, and its association with recent global urbanization and middle-class growth.
Thank you #ASMicrobe 2025 for an excellent conference in Los Angeles! It was great to meet new people and present our team's recent work with #AMR
June 24, 2025 at 1:51 PM
Thank you #ASMicrobe 2025 for an excellent conference in Los Angeles! It was great to meet new people and present our team's recent work with #AMR
Reposted
International comparison reveals gender differences in antimicrobial resistance - an analysis of more than 14,000 open gut metagenomes indicates that in high-income countries women had more antibiotic resistance than men www.utu.fi/en/news/pres... /w @katammp.bsky.social @mahkamehsalehi.bsky.social
International comparison reveals gender differences in antimicrobial resistance
A recent study led by the University of Turku, Finland, analysed the DNA map of more than 14,000 gut metagenomes in a global dataset and found that there are differences in antibiotic resistance be
www.utu.fi
June 22, 2025 at 8:51 AM
International comparison reveals gender differences in antimicrobial resistance - an analysis of more than 14,000 open gut metagenomes indicates that in high-income countries women had more antibiotic resistance than men www.utu.fi/en/news/pres... /w @katammp.bsky.social @mahkamehsalehi.bsky.social
Reposted
🦠🌍 Antibiotic resistance differs by gender
A global study of 14,000+ gut samples found women in high-income countries have 9% more antibiotic resistance genes than men.
In lower-income countries, patterns flip – but context matters.
🔗 www.nature.com/articles/s41...
#SciComm #AMR 🧪
A global study of 14,000+ gut samples found women in high-income countries have 9% more antibiotic resistance genes than men.
In lower-income countries, patterns flip – but context matters.
🔗 www.nature.com/articles/s41...
#SciComm #AMR 🧪
Gender differences in global antimicrobial resistance - npj Biofilms and Microbiomes
npj Biofilms and Microbiomes - Gender differences in global antimicrobial resistance
www.nature.com
June 18, 2025 at 8:17 PM
🦠🌍 Antibiotic resistance differs by gender
A global study of 14,000+ gut samples found women in high-income countries have 9% more antibiotic resistance genes than men.
In lower-income countries, patterns flip – but context matters.
🔗 www.nature.com/articles/s41...
#SciComm #AMR 🧪
A global study of 14,000+ gut samples found women in high-income countries have 9% more antibiotic resistance genes than men.
In lower-income countries, patterns flip – but context matters.
🔗 www.nature.com/articles/s41...
#SciComm #AMR 🧪
Kansainvälinen vertailu paljasti antibiooteille vastustuskykyisten bakteerien erot sukupuolten välillä www.utu.fi/fi/ajankohta...
Kansainvälinen vertailu paljasti antibiooteille vastustuskykyisten bakteerien erot sukupuolten välillä
Tuoreessa Turun yliopiston johtamassa tutkimuksessa analysoitiin yli 14 000 ulostemikrobiston DNA-karttaa ja havaittiin, että antibioottien vastustuskyvyssä eli resistenssissä on eroja sukupuolten
www.utu.fi
June 11, 2025 at 8:13 AM
Kansainvälinen vertailu paljasti antibiooteille vastustuskykyisten bakteerien erot sukupuolten välillä www.utu.fi/fi/ajankohta...
Reposted
Take home message! Recognizing gender and age-specific differences in AMR is essential for research and for creating fair healthcare strategies. For more details, data, and code, read the full study with @katammp.bsky.social et al. here: www.nature.com/articles/s41...
Gender differences in global antimicrobial resistance - npj Biofilms and Microbiomes
npj Biofilms and Microbiomes - Gender differences in global antimicrobial resistance
www.nature.com
May 22, 2025 at 6:55 AM
Take home message! Recognizing gender and age-specific differences in AMR is essential for research and for creating fair healthcare strategies. For more details, data, and code, read the full study with @katammp.bsky.social et al. here: www.nature.com/articles/s41...
Reposted
Age and geography were significant factors associated with resistome composition, with infants and the elderly showing higher ARG loads and diversity. This pattern underscores the impact of life stages on AMR.
May 22, 2025 at 6:55 AM
Age and geography were significant factors associated with resistome composition, with infants and the elderly showing higher ARG loads and diversity. This pattern underscores the impact of life stages on AMR.
Reposted
Genders share similar ARGs despite the difference in their abundance. Region and age explained far more variation in ARG composition than gender.
May 22, 2025 at 6:55 AM
Genders share similar ARGs despite the difference in their abundance. Region and age explained far more variation in ARG composition than gender.
Reposted
Gender differences in ARG abundance emerged in adulthood, indicating that gender-associated lifestyle, biological, or healthcare-related factors in adulthood may be linked to antibiotic resistance.
May 22, 2025 at 6:55 AM
Gender differences in ARG abundance emerged in adulthood, indicating that gender-associated lifestyle, biological, or healthcare-related factors in adulthood may be linked to antibiotic resistance.
Reposted
In LMICs, limited data indicated that when accounting for confounding factors such as age and socio-economics, the difference between men and women was not significant.
May 22, 2025 at 6:55 AM
In LMICs, limited data indicated that when accounting for confounding factors such as age and socio-economics, the difference between men and women was not significant.
Reposted
Women in HICs also showed slightly higher ARG diversity than men, suggesting a broader range of resistance genes present in their gut microbiomes.
May 22, 2025 at 6:55 AM
Women in HICs also showed slightly higher ARG diversity than men, suggesting a broader range of resistance genes present in their gut microbiomes.
Reposted
In high-income countries (HICs), women had 9% higher ARG abundance compared to men. This suggests that women in HICs may be more exposed to or carry more antibiotic-resistant bacteria. In low-income countries (LMICs), the trend was reversed. www.nature.com/articles/s41...
Gender differences in global antimicrobial resistance - npj Biofilms and Microbiomes
npj Biofilms and Microbiomes - Gender differences in global antimicrobial resistance
www.nature.com
May 22, 2025 at 6:55 AM
In high-income countries (HICs), women had 9% higher ARG abundance compared to men. This suggests that women in HICs may be more exposed to or carry more antibiotic-resistant bacteria. In low-income countries (LMICs), the trend was reversed. www.nature.com/articles/s41...
Reposted
Antimicrobial resistance #AMR is a major #globalhealth threat. How does it vary between genders? We analyzed 14,641 open human gut #metagenomes from 32 countries to investigate gender differences in #antibioticResistance genes (ARGs). www.nature.com/articles/s41...
Gender differences in global antimicrobial resistance - npj Biofilms and Microbiomes
npj Biofilms and Microbiomes - Gender differences in global antimicrobial resistance
www.nature.com
May 22, 2025 at 6:55 AM
Antimicrobial resistance #AMR is a major #globalhealth threat. How does it vary between genders? We analyzed 14,641 open human gut #metagenomes from 32 countries to investigate gender differences in #antibioticResistance genes (ARGs). www.nature.com/articles/s41...
Reposted
Did you know that the female #microbiome is unique in many ways, and antibiotic resistance in the gut microbiome varies between genders? See npj Biofilms and Microbiomes special issue, Women and their microbes, to learn more! www.nature.com/collections/...
Women and their microbes
This collection invites research on all aspects of women’s health involving the microbiome from different body sites and its interplay with fertility, ...
www.nature.com
May 22, 2025 at 6:55 AM
Did you know that the female #microbiome is unique in many ways, and antibiotic resistance in the gut microbiome varies between genders? See npj Biofilms and Microbiomes special issue, Women and their microbes, to learn more! www.nature.com/collections/...