Lab of Fish Immunology
@labfishimmunol.bsky.social
Scientific group of enthusiastic fish immunologists 🐟🐟🔬🧫led by
Dr. Tomas Korytar at BiologyCentre BC CAS 🇨🇿
https://sites.google.com/view/korytarlab/domovsk%C3%A1-str%C3%A1nka
Dr. Tomas Korytar at BiologyCentre BC CAS 🇨🇿
https://sites.google.com/view/korytarlab/domovsk%C3%A1-str%C3%A1nka
Pinned
KORYTAR LAB
Welcome to the Lab of Fish Immunology at the Biology Centre CAS
sites.google.com
Today we launched new lab webpage please check for any info
sites.google.com/view/korytar...
sites.google.com/view/korytar...
Wonderful evening while visiting our colleagues at Nihon Uni in Tokyo — great company, warm hospitality, and amazing food. Thank you so much for having us. 🙏🙂
November 15, 2025 at 4:05 AM
Wonderful evening while visiting our colleagues at Nihon Uni in Tokyo — great company, warm hospitality, and amazing food. Thank you so much for having us. 🙏🙂
Reposted by Lab of Fish Immunology
And then there is this preprint @biorxivpreprint.bsky.social, one I’m pretty excited about. A single cell sequencing atlas of a salmonid immune system, from brown trout. Weird B-cell/Neutrophil crossover cluster - what do immunologists think?
🐟 🔬 🧬 🦠 🧫 🌎
www.biorxiv.org/content/10.1...
🐟 🔬 🧬 🦠 🧫 🌎
www.biorxiv.org/content/10.1...
Single-cell RNA sequencing reveals influences of rearing environment on cellular immunity in brown trout (Salmo trutta)
The ability to profile gene expression at the single cell level can offer unprecedented insight into the vertebrate immune system. While such profiling of non-model organisms can present unique challe...
www.biorxiv.org
May 10, 2025 at 8:13 PM
And then there is this preprint @biorxivpreprint.bsky.social, one I’m pretty excited about. A single cell sequencing atlas of a salmonid immune system, from brown trout. Weird B-cell/Neutrophil crossover cluster - what do immunologists think?
🐟 🔬 🧬 🦠 🧫 🌎
www.biorxiv.org/content/10.1...
🐟 🔬 🧬 🦠 🧫 🌎
www.biorxiv.org/content/10.1...
Having a great time at the 5th ISFSI in Tainan, Taiwan! 🌏✨ Fantastic talks, inspiring science, and wonderful people — already looking forward to the next one! 🇹🇼🐟 #ISFSI2025 #Tainan #FisheriesScience #Aquaculture
November 7, 2025 at 7:48 AM
Having a great time at the 5th ISFSI in Tainan, Taiwan! 🌏✨ Fantastic talks, inspiring science, and wonderful people — already looking forward to the next one! 🇹🇼🐟 #ISFSI2025 #Tainan #FisheriesScience #Aquaculture
Reposted by Lab of Fish Immunology
Nature research paper: Diverging fish biodiversity trends in cold and warm rivers and streams
go.nature.com/42JFObR
go.nature.com/42JFObR
Diverging fish biodiversity trends in cold and warm rivers and streams - Nature
In the past three decades, fish abundance, richness and uniqueness have diverged across cold and warm streams, and the effects on native fish communities of stream warming and increases in introduced fishes have magnified each other.
go.nature.com
September 25, 2025 at 4:59 PM
Nature research paper: Diverging fish biodiversity trends in cold and warm rivers and streams
go.nature.com/42JFObR
go.nature.com/42JFObR
Great vibes at yesterday's project meeting with our awesome colleagues @CatrinUP @IFrebort
and @JihoceskaUni💡🧬 So many sparks flying already-this is gonna be fun! Go Barley go! 🚀🌾
and @JihoceskaUni💡🧬 So many sparks flying already-this is gonna be fun! Go Barley go! 🚀🌾
September 12, 2025 at 7:32 AM
Great vibes at yesterday's project meeting with our awesome colleagues @CatrinUP @IFrebort
and @JihoceskaUni💡🧬 So many sparks flying already-this is gonna be fun! Go Barley go! 🚀🌾
and @JihoceskaUni💡🧬 So many sparks flying already-this is gonna be fun! Go Barley go! 🚀🌾
Just having a great time at EAFP2025 in Crete ✈️. Talks delivered, briliant food, people, colleagues. Can't wait for the next one. 🇮🇸
September 3, 2025 at 3:21 PM
Just having a great time at EAFP2025 in Crete ✈️. Talks delivered, briliant food, people, colleagues. Can't wait for the next one. 🇮🇸
We were delighted to welcome our colleagues visiting us from 🇯🇵
Nihon Uni in Tokio
and Fukui Prefectural Uni
🤓 ありがとう ございま. It was a pleasure having you here with us. See u soon in Japan guys ✈️
Nihon Uni in Tokio
and Fukui Prefectural Uni
🤓 ありがとう ございま. It was a pleasure having you here with us. See u soon in Japan guys ✈️
August 26, 2025 at 10:06 AM
We were delighted to welcome our colleagues visiting us from 🇯🇵
Nihon Uni in Tokio
and Fukui Prefectural Uni
🤓 ありがとう ございま. It was a pleasure having you here with us. See u soon in Japan guys ✈️
Nihon Uni in Tokio
and Fukui Prefectural Uni
🤓 ありがとう ございま. It was a pleasure having you here with us. See u soon in Japan guys ✈️
Reposted by Lab of Fish Immunology
An automated tool (EPP) identifies distinct cell phenotypes in flow cytometry data through optimized 2D gating as shown in 4 published datasets. EPP\u2019s C++ code integrates with any software, as demonstrated in MATLAB with FlowJo.
@black-softail.net
www.nature.com/articles/s42...
@black-softail.net
www.nature.com/articles/s42...
Automatic phenotyping using exhaustive projection pursuit - Communications Biology
An automated tool (EPP) identifies distinct cell phenotypes in flow cytometry data through optimized 2D gating as shown in 4 published datasets. EPP’ C++ code integrates with any software, as demonstr...
www.nature.com
August 14, 2025 at 11:45 AM
An automated tool (EPP) identifies distinct cell phenotypes in flow cytometry data through optimized 2D gating as shown in 4 published datasets. EPP\u2019s C++ code integrates with any software, as demonstrated in MATLAB with FlowJo.
@black-softail.net
www.nature.com/articles/s42...
@black-softail.net
www.nature.com/articles/s42...
Reposted by Lab of Fish Immunology
Did you ever wonder what insights hide in the multiplets that are usually discarded in flow cytometry? 🫧 Find out in the first publication of my PhD, now out in Nature Methods! www.nature.com/articles/s41... (1/4)
August 7, 2025 at 8:48 PM
Did you ever wonder what insights hide in the multiplets that are usually discarded in flow cytometry? 🫧 Find out in the first publication of my PhD, now out in Nature Methods! www.nature.com/articles/s41... (1/4)
Reposted by Lab of Fish Immunology
Thanks Sheena it’s great to get some clearly explained immunology out into the world
I thought it might be helpful to do a more general immunology explainer which I can then build on for example when I discuss specific papers or political actions. Do let me know if its useful and other topics if so. This first one is a general one about how we tackle infections... 🧪 #ImmunoSky
Fundamental immunology 101: the basics of an immune response
Tackling infections
open.substack.com
August 5, 2025 at 8:35 AM
Thanks Sheena it’s great to get some clearly explained immunology out into the world
Reposted by Lab of Fish Immunology
Policarpo et al. use phylogenetic and synteny data to identify 19 teleost-to-teleost horizontal gene transfers, involving genes linked to immunity or pore formation; this suggests eukaryote-to-eukaryote HGT has shaped teleost evolution.
🔗 doi.org/10.1093/molbev/msaf107
#evolbio #molbio #fish
🔗 doi.org/10.1093/molbev/msaf107
#evolbio #molbio #fish
Multiple Horizontal Transfers of Immune Genes Between Distantly Related Teleost Fishes
Abstract. Horizontal gene transfer (HGT) is less frequent in eukaryotes than in prokaryotes, yet can have strong functional implications and was proposed a
doi.org
May 28, 2025 at 9:14 AM
Policarpo et al. use phylogenetic and synteny data to identify 19 teleost-to-teleost horizontal gene transfers, involving genes linked to immunity or pore formation; this suggests eukaryote-to-eukaryote HGT has shaped teleost evolution.
🔗 doi.org/10.1093/molbev/msaf107
#evolbio #molbio #fish
🔗 doi.org/10.1093/molbev/msaf107
#evolbio #molbio #fish
Reposted by Lab of Fish Immunology
Our latest paper is now out. A long standing collaboration with the Sunyer lab where our teams show the requirement for secretory IgM in the gut mucosa to control microbiota homeostasis and metabolism. Enjoy! #sIgM #mucosalimmunology www.nature.com/articles/s41...
Secretory IgM regulates gut microbiota homeostasis and metabolism - Nature Microbiology
Rainbow trout with depleted secretory IgM reveal interesting insights into the elusive role of this immunoglobulin in maintaining gut microbiota.
www.nature.com
May 27, 2025 at 3:57 AM
Our latest paper is now out. A long standing collaboration with the Sunyer lab where our teams show the requirement for secretory IgM in the gut mucosa to control microbiota homeostasis and metabolism. Enjoy! #sIgM #mucosalimmunology www.nature.com/articles/s41...
Reposted by Lab of Fish Immunology
From Genes to Pathways: A Curated Gene Approach to Accurate Pathway Reconstruction in Teleost Fish Transcriptomics
Hererra et al. 2025
Presents a curated gene list tailored for teleost fish transcriptomics
doi.org/10.1002/jez....
Hererra et al. 2025
Presents a curated gene list tailored for teleost fish transcriptomics
doi.org/10.1002/jez....
From Genes to Pathways: A Curated Gene Approach to Accurate Pathway Reconstruction in Teleost Fish Transcriptomics
A curated gene list for teleost fish transcriptomics enhances the interpretation of high volumes of data by focusing on key biological processes. This resource bridges gaps in automated annotations, ....
doi.org
May 2, 2025 at 10:21 AM
From Genes to Pathways: A Curated Gene Approach to Accurate Pathway Reconstruction in Teleost Fish Transcriptomics
Hererra et al. 2025
Presents a curated gene list tailored for teleost fish transcriptomics
doi.org/10.1002/jez....
Hererra et al. 2025
Presents a curated gene list tailored for teleost fish transcriptomics
doi.org/10.1002/jez....
Reposted by Lab of Fish Immunology
My Bioinformatics Bootcamp turned blog! Enjoy this collection of free #zebrafish resources, now posted on @the-node.bsky.social. While not comprehensive, it gives an assortment of cools tools available to researchers. Feedback would be appreciated! thenode.biologists.com/bioinformati...
May 18, 2025 at 12:18 PM
Reposted by Lab of Fish Immunology
Hiding in plain sight: A new lymphoid organ discovered in #zebrafish. Mohamed Bakr and David Langenau discuss new work from @zebrafish007.bsky.social @zebrafishmk.bsky.social and colleagues (rupress.org/jem/article/...) in Insights: rupress.org/jem/article/...
April 25, 2025 at 2:05 PM
Hiding in plain sight: A new lymphoid organ discovered in #zebrafish. Mohamed Bakr and David Langenau discuss new work from @zebrafish007.bsky.social @zebrafishmk.bsky.social and colleagues (rupress.org/jem/article/...) in Insights: rupress.org/jem/article/...
Three research groups@fbndummerstorf Uni of Vet in Hannover and Faculty of Fisheries from Vodňany met in our lab to do some science together. Such a great moments a lot of sampling we did 🐟🧪🧪🧪🫡 and also became TV stars 😅😅
March 25, 2025 at 8:31 PM
Three research groups@fbndummerstorf Uni of Vet in Hannover and Faculty of Fisheries from Vodňany met in our lab to do some science together. Such a great moments a lot of sampling we did 🐟🧪🧪🧪🫡 and also became TV stars 😅😅
Truly amazing 👏👏👏👏 Deep-tissue transcriptomics and subcellular imaging at high spatial resolution | Science www.science.org/doi/10.1126/...
Deep-tissue transcriptomics and subcellular imaging at high spatial resolution
Limited color channels in fluorescence microscopy have long constrained spatial analysis in biological specimens. Here, we introduce cycle Hybridization Chain Reaction (HCR), a method that integrates ...
www.science.org
March 11, 2025 at 8:12 PM
Truly amazing 👏👏👏👏 Deep-tissue transcriptomics and subcellular imaging at high spatial resolution | Science www.science.org/doi/10.1126/...
Today we launched new lab webpage please check for any info
sites.google.com/view/korytar...
sites.google.com/view/korytar...
KORYTAR LAB
Welcome to the Lab of Fish Immunology at the Biology Centre CAS
sites.google.com
March 6, 2025 at 3:00 PM
Today we launched new lab webpage please check for any info
sites.google.com/view/korytar...
sites.google.com/view/korytar...
Just having a great time full of hard work at Friedrich Loeffler Institute
🏢. Fish cells are the best 🐟🐟🐟🧪🧪🧪
🏢. Fish cells are the best 🐟🐟🐟🧪🧪🧪
February 27, 2025 at 1:03 PM
Just having a great time full of hard work at Friedrich Loeffler Institute
🏢. Fish cells are the best 🐟🐟🐟🧪🧪🧪
🏢. Fish cells are the best 🐟🐟🐟🧪🧪🧪
Reposted by Lab of Fish Immunology
There is a disconnect between the current molecular, morphological and functional descriptions of cells in most nervous systems
https://go.nature.com/4jUeXRq
https://go.nature.com/4jUeXRq
Does a cell’s gene expression always reflect its function?
Transcriptionally similar neurons can be functionally diverse.
go.nature.com
February 12, 2025 at 6:36 PM
There is a disconnect between the current molecular, morphological and functional descriptions of cells in most nervous systems
https://go.nature.com/4jUeXRq
https://go.nature.com/4jUeXRq
Reposted by Lab of Fish Immunology
February issue now online: www.nature.com/nri/volumes/...
Cover image inspired by the Perspective 'Understanding vertebrate immunity through comparative immunology' bit.ly/3EoZqJ1 by Thomas Boehm
#immunosky #immunology
Cover image inspired by the Perspective 'Understanding vertebrate immunity through comparative immunology' bit.ly/3EoZqJ1 by Thomas Boehm
#immunosky #immunology
February 4, 2025 at 11:01 AM
February issue now online: www.nature.com/nri/volumes/...
Cover image inspired by the Perspective 'Understanding vertebrate immunity through comparative immunology' bit.ly/3EoZqJ1 by Thomas Boehm
#immunosky #immunology
Cover image inspired by the Perspective 'Understanding vertebrate immunity through comparative immunology' bit.ly/3EoZqJ1 by Thomas Boehm
#immunosky #immunology
Reposted by Lab of Fish Immunology
Cool work, very smart are these macrophage guys 👏👏
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Innate Immune Memory is Stimulus Specific
Innate immune memory (also termed trained immunity) is defined in part by its ability to cross-protect against heterologous pathogens, and can be generated by many different stimuli, suggesting a “uni...
www.biorxiv.org
February 3, 2025 at 10:04 PM
Cool work, very smart are these macrophage guys 👏👏
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Lab of Fish Immunology
B cell subsets have different capacities for phagocytosis and subsequent presentation of antigen to cognate T cells https://www.biorxiv.org/content/10.1101/2025.01.28.635276v1
February 2, 2025 at 3:17 AM
B cell subsets have different capacities for phagocytosis and subsequent presentation of antigen to cognate T cells https://www.biorxiv.org/content/10.1101/2025.01.28.635276v1
Went for "shopping" samples downstairs to @FishProtLab
at the Biology Centre CAS 😅🛒🛒 #movingstuff to 🆕lab...
at the Biology Centre CAS 😅🛒🛒 #movingstuff to 🆕lab...
January 31, 2025 at 11:08 PM
Went for "shopping" samples downstairs to @FishProtLab
at the Biology Centre CAS 😅🛒🛒 #movingstuff to 🆕lab...
at the Biology Centre CAS 😅🛒🛒 #movingstuff to 🆕lab...