For this who are unaware, the reason NIH now posts these data habitually on the data book site is… Jeremy Berg. He pioneered this openness as NIGMS Director.

🧠New paper alert!
We define PI-2620 tau PET cutpoints in a diverse cohort — summary of 🗝️ findings below ⬇️
675 adults:
• AB+ cognitively impaired (CI)
• AB– cognitively unimpaired (CU)
• 28% Hispanic, 31% NH Black, 41% NH White
🔗 Read it here:
(bit.ly/44RLVwe)
@victoriatennant.bsky.social

Did you control for how many users you have on both platforms?

🎉Congrats to PhD student, Amaryllis Tsiknia, who led our new paper bit.ly/3ZndVVh studying how diabetes relates to cortical thickness in Hispanic & non-Hispanic Black & White older adults!

Read more here: bit.ly/3GS0Ddj
More on our findings soon...

Blood-based biomarkers of Alzheimer’s disease and incident dementia in the community

Increased p-tau181, p-tau217, NfL, and GFAP demonstrated strong predictive performance (area under the curve ranging from 70.9% to 82.6%) for 10-year all-cause and AD dementia

www.nature.com/articles/s41...

The crush of new grant cancellations hasn't let up.

If your grant was terminated (or your app was pulled) please use this Google Form👇 to submit details for tracking purposes.

Multiple advocacy efforts are moving forward, but we must must must know more about what grants were cancelled and why.

Some good-ish news from NIH

“Federal Register notices for study sections run by CSR (but not those by ICs) will start being permitted again”

As far as I know, the timing for this is not clear, but I will be checking the Federal Register.

41/47 (87%) of NIH study sections are cancelled this week

Frustrating to see all this good research stalled (& not funded)

You can search for study sections that ‘did not meet as scheduled’ here with ones with * ⤵️
www.csr.nih.gov/RevPanelsAnd...

What can we do to get Science Magazine to drop their paywall for a while, while all this critically important news is being reported on? The public needs to know. Great journalists are covering these stories. where will they and the magazine be without the scientists and the research?

These cases are just incredible

I just wanted to share that I received the NoA for the second year of my R21 today. I know people are feeling anxious and I just hope some good news from the NIH can help. Hang in there - we'll get through this! ❤️

“The impact of the collective executive orders and directives appears devastating.” scim.ag/40ureTO

I got a lot of insights into how AI might work in scientific research from this convo:
www.theatlantic.com/podcasts/arc...

The importance of sleep microarchitecture- in addition to total sleep time - for cognition

academic.oup.com/sleep/articl...

Welcome!

Survival bias? Those who can no longer navigate drop out of these professions as they get older?

A Nature Aging paper identifies 13 proteins linked to brain aging. Changes in the concentrations of these blood proteins may peak at 57, 70, and 78 years old, and suggest that these ages may be important for potential interventions in the brain aging process. https://go.nature.com/3ZvGLSy 🧪

Agree that the current system sucks, but how would this work in practice?
1) Paying a flat rate per paper may incentivize rejections.
2) Paying for each step in the review process may incentivize more revisions.

Just watched the full House hearing & testimony of NIH Director Dr. Monica Bertignolli.

A few takeaways:
• the proposed budget, in addition to not increasing for inflation, wants to condense NIH from 27 to 15 institutes. The NIH does not think this is a good idea.

🧵1/?

Hi, please add me as well. Thank you!

Hi, please add me